Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.

for Degenerative Disc Disease

Sites in Sacramento +1 more location

Sponsor: Highridge Medical

Sex: All·Age: 22 - 69

Code: NCT06485206·Recruiting·Listed Jul 2024

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Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis

for Osteoarthritis

Sites in Valencia +1 more location

Sponsor: Healeon Medical Inc

Sex: All·Age: 18 - 90

Code: NCT04238143·Recruiting·Listed Jan 2020

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Prospective Study on Power Prenatal Vitamins for Males on YO Score At-home Sperm Test Results

for Spermatogenesis and Semen Disorders

1 location in Encino

Sponsor: The Bird and Be Co Inc

Sex: Male·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05951075·Recruiting·Listed Jul 2023

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Computer-Assisted Hair Restoration Study Using ARTAS System

for Androgenic Alopecia

1 location in San Jose

Sponsor: Venus Concept

Sex: Male·Age: 20 - 70

Code: NCT05938569·Recruiting·Listed Jul 2023

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CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

for Advanced Clear Cell Renal Cell Carcinoma

Drug: Ipilimumab

1 location in Duarte

Sponsor: Osel, Inc.

Sex: All·Age: 18+

Code: NCT06399419·Phase 1·Recruiting·Listed May 2024

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AETOS Shoulder System

for Shoulder Osteoarthritis

Sites in San Francisco +4 more locations

Sponsor: Smith & Nephew, Inc.

Sex: All·Age: 18+

Code: NCT06319911·Recruiting·Listed Mar 2024

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Safety and Feasibility of Umbilical Cord Wharton's Jelly Allograft Injections for Lumbar Pain

for Low Back Pain

Sites in Beverly Hills +3 more locations

Sponsor: R3 Stem Cell

Sex: All·Age: 20+

Code: NCT06361485·Phase 1·Recruiting·Listed Apr 2024

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Development and Analysis of a Stool Bank for Cancer Patients

for Carcinoma, Non-Small-Cell Lung

Sites in Fountain Valley +1 more location

Sponsor: Persephone Biosciences

Sex: All·Age: 18+

Code: NCT04291755·Recruiting·Listed Mar 2020

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xPedite: A Study to Expedite DIPG and DMG Research

for Oncology

1 location in Los Altos

Sponsor: xCures

Sex: All·Age: All ages

Code: NCT06140719·Recruiting·Listed Nov 2023

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A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABSK112 in Patients With Non-Small Cell Lung Cancer

for Non-Small Cell Lung Cancer

1 location in Beverly Hills

Sponsor: Abbisko Therapeutics Co, Ltd

Sex: All·Age: 18+

Code: NCT06225804·Phase 1·Recruiting·Listed Jan 2024

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Physica System Total Knee Replacement Registry Study

for Osteoarthritis, Knee

Sites in Rancho Mirage +2 more locations

Sponsor: Limacorporate S.p.a

Sex: All·Age: 22+

Code: NCT03048201·Recruiting·Listed Feb 2017

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Phase I Human Analytics (HALO) Study

for Cardiovascular Diseases

1 location in Indian Wells

Sponsor: HALO Diagnostics

Sex: Male·Age: 45 - 90

Code: NCT05423860·Recruiting·Listed Jun 2022

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Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

for Autoimmune Diseases

1 location in Culver City

Sponsor: Thomas Advanced Medical LLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04684602·Phase 1, Phase 2·Recruiting·Listed Dec 2020

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An Adaptive Phase II/III, Two-Part, Double-Blind, Randomized, Placebo-controlled, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen®, as an Add-on Therapy With Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults

for Refractory Schizophrenia

1 location in Pasadena

Sponsor: SyneuRx International (Taiwan) Corp

Sex: All·Age: 18 - 55

Code: NCT03094429·Phase 2, Phase 3·Recruiting·Listed Mar 2017

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A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

for Multiple System Atrophy

Sites in Los Angeles +5 more locations

Sponsor: Dasher Neuroscience Inc.

Sex: All·Age: 30+

Code: NCT06848231·Phase 2·Recruiting·Listed Feb 2025

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Padeliporfin VTP Treatment for Unresectable Pancreatic Adenocarcinoma

for Locally Advanced Unresectable Pancreatic Adenocarcinoma

Sites in Duarte & Irvine

Sponsor: Impact Biotech Ltd

Sex: All·Age: 18+

Code: NCT05919238·Phase 1·Recruiting·Listed Jun 2023

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Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome

for Netherton Syndrome

1 location in Palo Alto

Sponsor: Azitra Inc.

Sex: All·Age: 18+

Code: NCT06137157·Phase 1·Recruiting·Listed Nov 2023

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Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.

for Acute Respiratory Distress Syndrome

Sites in Newport Beach +4 more locations

Sponsor: Vasomune Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05123755·Phase 2·Recruiting·Listed Nov 2021

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In Vivo Cross-Modal Imaging of Skin

for Skin

1 location in Mountain View

Sponsor: Gabriel Sanchez

Sex: All·Age: 2 - 90·Accepts healthy volunteers

Code: NCT07188948·Recruiting·Listed Sep 2025

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A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder

for Social Anxiety Disorder

Sites in Walnut Creek, Sherman Oaks +5 more locations

Sponsor: VistaGen Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT06809179·Phase 2·Recruiting·Listed Feb 2025

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Isunakinra Alone and in Combination With Pembrolizumab in Patients With Colorectal Cancer (MSS)

for Colorectal Cancer Metastatic

Sites in Los Angeles & Newport Beach

Sponsor: Buzzard Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06634875·Phase 2·Recruiting·Listed Oct 2024

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Early Feasibility Study of "HyperQureTM RDN System", Laparoscopic Renal Denervation Therapy, in Patients With Resistant Hypertension

for Resistant Hypertension

Sites in Orange, Stanford +3 more locations

Sponsor: DeepQure Inc.

Sex: All·Age: 22 - 80

Code: NCT06526858·Recruiting·Listed Jul 2024

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Acute Partial Thickness Burn Study Comparing Transforming Powder Dressing to Standard of Care Dressing

for Wounds and Injuries

Sites in Orange +5 more locations

Sponsor: ULURU Inc.

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05424354·Phase 4·Recruiting·Listed Jun 2022

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Remote Electrical Stimulation as a Long-term Intervention for Endometriosis Flare Ups

for Endometriosis

1 location in San Francisco

Sponsor: Samphire Group, Inc.

Sex: Female·Age: 22 - 45

Code: NCT06974773·Recruiting·Listed May 2025

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A Phase II, Placebo Controlled, Clinical Trial of Topical TolaSure Targeting Aggregated Mutant Keratin in Epidermolysis Bullosa Simplex

for Epidermolysis Bullosa Simplex

Sites in Palo Alto +1 more location

Sponsor: BioMendics, LLC

Sex: All·Age: 4+

Code: NCT07027345·Phase 2·Recruiting·Listed Jun 2025

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A Multicenter Study in Bronchoscopy Combining Stimulated Raman Histology With Artificial Intelligence for Rapid Lung Cancer Detection - The ON-SITE Study

for Lung Biopsy

Sites in San Diego +4 more locations

Sponsor: Invenio Imaging Inc.

Sex: All·Age: 22+

Code: NCT07045103·Recruiting·Listed Jul 2025

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Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

for Cirrhosis, Liver

Sites in Coronado +8 more locations

Sponsor: PharmaIN

Sex: All·Age: 18 - 75

Code: NCT05490888·Phase 1·Recruiting·Listed Aug 2022

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Safety and Tolerability of IMM01-STEM in Patients With Muscle Atrophy Related to Knee Osteoarthritis.

for Muscle Atrophy

1 location in Irvine

Sponsor: Immunis, Inc.

Sex: All·Age: 50 - 75·Accepts healthy volunteers

Code: NCT05211986·Phase 1, Phase 2·Recruiting·Listed Jan 2022

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Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

for Diabetic Foot Ulcer

Sites in Santa Rosa +6 more locations

Sponsor: Cellution Biologics

Sex: All·Age: 18+

Code: NCT07014176·Phase 4·Recruiting·Listed Jun 2025

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Safety and Device Performance of the Uriprene® Degradable Temporary Ureteral Stent Following Uncomplicated Ureteroscopy

for Ureteral Diseases

Sites in Los Angeles +3 more locations

Sponsor: Adva-Tec

Sex: All·Age: 21 - 80

Code: NCT04565795·Recruiting·Listed Sep 2020

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A Study of LM-24C5 For Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Los Angeles +5 more locations

Sponsor: LaNova Medicines Limited

Sex: All·Age: 18+

Code: NCT06187402·Phase 1, Phase 2·Recruiting·Listed Jan 2024

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Phase 1b/2a Randomized Double-blind Study to Investigate Safety Tolerability PK PD Preliminary Efficacy of Oral Administration of SNIPR001 in Patients With Hematologic Malignancy Scheduled for Allogeneic Hematopoietic Stem-Cell Transplant Receiving FQ Prophylaxis & Harboring FQR Ecoli Pre-Transplant

for E Coli Infections

Sites in San Francisco, Duarte +6 more locations

Sponsor: SNIPR Biome Aps.

Sex: All·Age: 18+

Code: NCT06938867·Phase 1, Phase 2·Recruiting·Listed Apr 2025

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Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for Cancer

Sites in Palo Alto, Duarte +3 more locations

Sponsor: RefleXion Medical

Sex: All·Age: All ages

Code: NCT05406167·Recruiting·Listed Jun 2022

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A Study of Tegavivint (BC2059) in Patients With Advanced Hepatocellular Carcinoma

for Advanced Hepatocellular Carcinoma

Sites in Duarte +6 more locations

Sponsor: Iterion Therapeutics

Sex: All·Age: 18+

Code: NCT05797805·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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A Research Study to Evaluate the Safety of NNC4004-0002 When Given to Participants With Asymptomatic Hyperuricemia

for Healthy Volunteers

Sites in Glendale +1 more location

Sponsor: Novo Nordisk A/S

Sex: All·Age: 35 - 75·Accepts healthy volunteers

Code: NCT06859073·Phase 1·Recruiting·Listed Mar 2025

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Plexaa For Preconditioning: Gender Affirming Mastectomy

for Nipple Necrosis

1 location in Palo Alto

Sponsor: Plexaa Ltd

Sex: Female·Age: 18+

Code: NCT06502353·Recruiting·Listed Jul 2024

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Safety Study for a Gamma Delta T Cell Product Used With Low Dose Radiotherapy in Patients With Locally Advanced or Metastatic NSCLC or Solid Tumors With Bone Metastases

for Carcinoma, Non-Small-Cell Lung Cancer

Sites in Beverly Hills +4 more locations

Sponsor: Kiromic BioPharma Inc.

Sex: All·Age: 18+

Code: NCT06069570·Phase 1·Recruiting·Listed Oct 2023

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Observe Change in Nasal Swab DRD2 Gene Expression in Restless Legs Syndrome (RLS) Patients on Prolonged Dopamine Agonist Treatment

for Restless Leg Syndrome (RLS)

1 location in San Francisco

Sponsor: HBC Immunology Inc

Sex: All·Age: 18 - 60

Code: NCT06726785·Recruiting·Listed Dec 2024

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Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)

for Diabetic Foot Infection

Sites in Vista & Corona

Sponsor: MicuRx

Sex: All·Age: 18+

Code: NCT05369052·Phase 3·Recruiting·Listed May 2022

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MSC EVs in Dystrophic Epidermolysis Bullosa

for Dystrophic Epidermolysis Bullosa

Sites in Los Angeles +2 more locations

Sponsor: Aegle Therapeutics

Sex: All·Age: 6 Months+

Code: NCT04173650·Phase 1, Phase 2·Recruiting·Listed Nov 2019

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