Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

for Metastatic Malignant Solid Neoplasm

Sites in Los Angeles, San Diego +16 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05687110·Phase 1·Recruiting·Listed Jan 2023

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A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma

for Neuroblastoma Recurrent

Sites in San Francisco +3 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 30

Code: NCT07085338·Phase 2·Recruiting·Listed Jul 2025

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for Metastatic Colorectal Carcinoma

Sites in Orange, Irvine +11 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05803382·Phase 1·Recruiting·Listed Apr 2023

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Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)

for Delirium

Sites in Los Angeles, San Francisco +12 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 60+

Code: NCT06192615·Phase 3·Recruiting·Listed Jan 2024

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Evaluation of Clinical Outcomes and Acceptability of an Anatomical Classification for Placenta Accreta Spectrum

for Placenta Accreta

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: Female·Age: 18 - 55

Code: NCT07283042·Recruiting·Listed Dec 2025

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Blood Flow Restriction Training as a Targeted Intervention for Rowers With Back Pain.

for Low Back Pain

1 location in Loma Linda

Sponsor: Loma Linda University

Sex: All·Age: 13 - 20·Accepts healthy volunteers

Code: NCT07130812·Recruiting·Listed Aug 2025

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Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in Sacramento, Santa Rosa +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

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PSMA PET for the Staging and Management of Hepatocellular Carcinoma

for Hepatocellular Carcinoma (HCC)

Sites in West Los Angeles +1 more location

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT07019844·Recruiting·Listed Jun 2025

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Embryonal Tumor With Multilayered Rosettes

for Embryonal Tumor With Multilayered Rosettes

Sites in San Francisco +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: All ages

Code: NCT06861244·Phase 2·Recruiting·Listed Mar 2025

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CTSN Embolic Protection Trial

for Delirium

Sites in Los Angeles +18 more locations

Sponsor: Icahn School of Medicine at Mount Sinai

Sex: All·Age: 60+

Code: NCT06027788·Recruiting·Listed Sep 2023

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An International Observational Study of Adults With Acute Infection

for Infectious Disease

Sites in San Francisco, Palo Alto +18 more locations

Sponsor: University of Minnesota

Sex: All·Age: 18+

Code: NCT07069400·Recruiting·Listed Jul 2025

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Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90

for Hepatocellular Carcinoma (HCC)

1 location in Palo Alto

Sponsor: Palo Alto Veterans Institute for Research

Sex: All·Age: 18+

Code: NCT07303712·Recruiting·Listed Dec 2025

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Gastroschisis Outcomes of Delivery (GOOD) Study

for Gastroschisis

Sites in Stanford, Loma Linda +34 more locations

Sponsor: Medical College of Wisconsin

Sex: Female·Age: 18+

Code: NCT02774746·Recruiting·Listed May 2016

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Childhood Cancer Survivor Study

for Cancer

Sites in Los Angeles, San Francisco +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer

for Metastatic Prostate Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT07145177·Phase 1·Recruiting·Listed Aug 2025

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Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies

for Soft-tissue Sarcoma

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07064018·Phase 1, Phase 2·Recruiting·Listed Jul 2025

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SARC046: A Phase II Trial of Nab-Sirolimus in Patients With Progressing or Symptomatic Epithelioid Hemangioendothelioma

for Epithelioid Hemangioendothelioma (EHE)

Sites in Stanford +5 more locations

Sponsor: Sarcoma Alliance for Research through Collaboration

Sex: All·Age: 18+

Code: NCT07104331·Phase 2·Recruiting·Listed Aug 2025

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Los Angeles, San Francisco +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Training Reward Responsiveness Through Virtual Reality

for Positive Affect

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 18+

Code: NCT07219875·Phase 2·Recruiting·Listed Oct 2025

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Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

for Spinal Fusion

Sites in San Francisco, Sacramento +6 more locations

Sponsor: AO Foundation, AO Spine

Sex: All·Age: 45+

Code: NCT06368245·Recruiting·Listed Apr 2024

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in Los Angeles, San Francisco +643 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

Sites in Los Angeles, San Francisco +11 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting·Listed Jun 2024

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Vascular Optimized Radiotherapy Tuned to Critical Structures for Erectile Function Using High-Precision X-Ray Treatment

for Prostate Cancer

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Male·Age: 18+

Code: NCT07293585·Phase 3·Recruiting·Listed Dec 2025

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SB-4826 in Adult Participants With Locally Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphomas

for Non Hodgkin Lymphoma

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT07222631·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Chronic Infections and Inflammation in ME/CFS: An Observational Study

for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07227441·Recruiting·Listed Nov 2025

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Nephrotic Syndrome Study Network

for Minimal Change Disease (MCD)

Sites in Los Angeles, San Francisco +32 more locations

Sponsor: University of Michigan

Sex: All·Age: Up to 80

Code: NCT01209000·Recruiting·Listed Sep 2010

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Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

for Myotonic Dystrophy 1

Sites in Los Angeles, La Jolla +8 more locations

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18 - 70

Code: NCT03981575·Recruiting·Listed Jun 2019

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Automated Insulin for Management of Intrapartum Glycemia

for Type 1 Diabetes (T1D)

Sites in Los Angeles, San Francisco & San Diego

Sponsor: University of California, San Francisco

Sex: Female·Age: 18 - 55

Code: NCT06883344·Recruiting·Listed Mar 2025

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Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein β-Catenin, The SAPHIRE Trial

for Advanced Hepatocellular Carcinoma

Drug: Cabozantinib

Sites in Orange, Irvine +2 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06811116·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

Sites in Los Angeles, San Diego +15 more locations

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting·Listed May 2023

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IA Lidocaine and Methylprednisolone for Headache Associated With Subarachnoid Hemorrhage

for Headaches Associated With Subarachnoid Hemorrhage (SAH)

1 location in San Francisco

Sponsor: Daniel Raper, MBBS

Sex: All·Age: 18+

Code: NCT07054801·Phase 2·Recruiting·Listed Jul 2025

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Advanced SPinal Innovations With Robotics and Enabling Technology Registry

for Spine Deformity

Sites in Los Angeles +9 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 21·Accepts healthy volunteers

Code: NCT05071144·Recruiting·Listed Oct 2021

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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

Sites in San Diego, Palo Alto +38 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting·Listed Oct 2022

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Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)

for PSC

Sites in San Francisco, Sacramento +9 more locations

Sponsor: PSC Partners Seeking a Cure

Sex: All·Age: 18 - 75

Code: NCT06297993·Recruiting·Listed Mar 2024

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PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors

for Refractory Solid Tumors

Sites in Los Angeles, San Francisco +5 more locations

Sponsor: Theodore Laetsch

Sex: All·Age: 1 - 30

Code: NCT06721689·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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Glofitamab With Pirtobrutinib for Relapsed or Refractory Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Los Angeles, San Francisco & Davis

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06252675·Phase 2·Recruiting·Listed Feb 2024

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Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

for Liver Transplant

Sites in San Francisco +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06280950·Phase 2·Recruiting·Listed Feb 2024

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Promoting Physical Activity in Older Hispanic/Latino(a) Adults

for Sedentary Behavior

Sites in San Diego +1 more location

Sponsor: Kaiser Permanente

Sex: All·Age: 55 - 89·Accepts healthy volunteers

Code: NCT06362824·Recruiting·Listed Apr 2024

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Multimodal Profiling of Response to Pediatric Comprehensive Behavioral Intervention for Tics

for Tourette Syndrome

Sites in San Diego +1 more location

Sponsor: University of Minnesota

Sex: All·Age: 10 - 17

Code: NCT06194305·Phase 2·Recruiting·Listed Jan 2024

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Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children

for Hemorrhagic Shock

Sites in Sacramento +19 more locations

Sponsor: Philip Spinella

Sex: All·Age: Up to 17

Code: NCT06070350·Phase 3·Recruiting·Listed Oct 2023

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