Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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International CRDS Registry

for Calcium Release Deficiency Syndrome

Sites in San Francisco +3 more locations

Sponsor: Population Health Research Institute

Sex: All·Age: All ages

Code: NCT06508164·Recruiting·Listed Jul 2024

Apply to this trial

A Dose Escalation Study of Levetiracetam in the Treatment of Neonatal Seizures

for Neonatal Seizure

Sites in San Diego +1 more location

Sponsor: University of California, San Diego

Sex: All·Age: Up to 1 Month

Code: NCT05610085·Phase 2·Recruiting·Listed Nov 2022

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Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease

for Rhabdomyosarcoma

Drug: Irinotecan

Sites in Palo Alto +2 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: Up to 22

Code: NCT06023641·Phase 2·Recruiting·Listed Sep 2023

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Alzheimer's Tau Platform: Master Protocol

for Preclinical Alzheimer's Disease

1 location in San Francisco

Sponsor: Paul S. Aisen

Sex: All·Age: 50 - 80

Code: NCT06957418·Phase 2·Recruiting·Listed May 2025

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Sacramento +8 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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Study EHR Risk Stratification Tools

for Prediabetes

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 65+

Code: NCT06995378·Recruiting·Listed May 2025

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Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06996119·Phase 1·Recruiting·Listed May 2025

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Evaluation of Dipyridamole in Preventing Post-Transplant Hypophosphatemia in Kidney Transplant Recipients

for Hypophosphatemia

1 location in Stanford

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06824454·Phase 2·Recruiting·Listed Feb 2025

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Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

for Anatomic Stage I Breast Cancer AJCC v8

Sites in La Jolla, Duarte & Riverside

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT06763328·Phase 3·Recruiting·Listed Jan 2025

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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

Drug: Cemiplimab

Sites in Orange, Irvine +4 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06980038·Phase 2·Recruiting·Listed May 2025

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Effect of Daily Mixed Spice Consumption on Memory Function

for Memory

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 50 - 80·Accepts healthy volunteers

Code: NCT06889961·Recruiting·Listed Mar 2025

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Breast Cancer Screening Adherence for Women at Moderate Risk for Breast Cancer

for Breast Carcinoma

2 locations in Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 30 - 75·Accepts healthy volunteers

Code: NCT07076147·Recruiting·Listed Jul 2025

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Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

for Heart Failure

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT06877169·Recruiting·Listed Mar 2025

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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sites in Palo Alto, Irvine +16 more locations

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting·Listed May 2024

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Losartan + Sunitinib in Treatment of Osteosarcoma

for Osteosarcoma

Sites in Los Angeles +3 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 10+

Code: NCT03900793·Phase 1·Recruiting·Listed Apr 2019

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Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

for Pain, Postoperative

Sites in Redwood City +1 more location

Sponsor: Stanford University

Sex: All·Age: 45+

Code: NCT04676802·Phase 2·Recruiting·Listed Dec 2020

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Probiotic Administration for Adolescent Depression

for Depression

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 15 - 24

Code: NCT06898788·EARLY_Phase 1·Recruiting·Listed Mar 2025

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Tranexamic Acid for Second Trimester Dilation and Evacuation and Bleeding Outcomes

for Abortion

Sites in San Diego +2 more locations

Sponsor: University of California, San Diego

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06820177·Phase 4·Recruiting·Listed Feb 2025

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Palo Alto +24 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

for Autoimmune Disease

Drug: Nivolumab

Sites in Sacramento +40 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03816345·Phase 1·Recruiting·Listed Jan 2019

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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for Multiple Myeloma

Sites in Duarte, Irvine +9 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225738·Recruiting·Listed Nov 2025

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Time Restricted Eating in Patients With Microalbuminuria

for Type 2 Diabetes Mellitus (T2DM)

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 75

Code: NCT06884059·Phase 1·Recruiting·Listed Mar 2025

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Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

for Locally Advanced Rectal Adenocarcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06834126·Phase 1·Recruiting·Listed Feb 2025

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Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy

for Psoriatic Arthritis

Drug: Guselkumab

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: All ages

Code: NCT06586281·Recruiting·Listed Sep 2024

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Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

for HIV-1-infection

Sites in San Diego +9 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06071767·Phase 1, Phase 2·Recruiting·Listed Oct 2023

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5-Day Preoperative Radiation for Soft Tissue Sarcoma

for Soft Tissue Sarcoma

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT06087861·Phase 2·Recruiting·Listed Oct 2023

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Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

for Metastatic Urothelial Carcinoma

Sites in La Jolla, Duarte +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06439836·Phase 1·Recruiting·Listed Jun 2024

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Trigeminal Nerve Stimulation for Children With Prenatal Alcohol Exposure

for Fetal Alcohol Spectrum Disorders

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 8 - 12

Code: NCT06847165·Recruiting·Listed Feb 2025

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BElumosudil for Bronchiolitis Obliterans Prevention/Therapy (BEBOP)

for Bronchiolitis Obliterans Syndrome

Sites in Stanford +5 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT05922761·Phase 2·Recruiting·Listed Jun 2023

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Antibiotic Cement Bead Pouch Versus Negative Pressure Wound Therapy

for Open tíbia Fracture

Sites in Los Angeles, Orange +25 more locations

Sponsor: University of Maryland, Baltimore

Sex: All·Age: 18+

Code: NCT05615844·Phase 3·Recruiting·Listed Nov 2022

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Telehealth vs In-Person Evaluation of Addiction Treatment After Visiting the Emergency Department

for Opioid Use Disorder

Sites in Sacramento, Sylmar & El Centro

Sponsor: University of California, Davis

Sex: All·Age: 18+

Code: NCT06961058·Recruiting·Listed May 2025

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LDL-C Optimization Using Inclisiran in Patients in Which Drug-Drug Interactions Limit LDL Lowering

for Drug Interactions

Drug: Inclisiran

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 85

Code: NCT06865885·Phase 4·Recruiting·Listed Mar 2025

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Building Resilient Families

for Adverse Childhood Experiences

1 location in Loma Linda

Sponsor: Loma Linda University

Sex: All·Age: 3 - 11·Accepts healthy volunteers

Code: NCT05388864·Recruiting·Listed May 2022

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

Sites in San Francisco +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting·Listed Jan 2025

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DoD AtMS for Posttraumatic Peripheral Neuropathic Pain

for Posttraumatic Peripheral Neuropathic Pain

1 location in San Diego

Sponsor: Veterans Medical Research Foundation

Sex: All·Age: 18+

Code: NCT07301177·Recruiting·Listed Dec 2025

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Duvelisib and Venetoclax in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

for T-cell-prolymphocytic Leukemia

Drug: Venetoclax

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06810778·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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A Randomized Pilot rTMS Trial for Knee Arthritis Pain and Depression

for Knee Osteoarthritis

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 50 - 95

Code: NCT06906939·EARLY_Phase 1·Recruiting·Listed Apr 2025

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Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery

for Clear Cell Renal Cell Carcinoma

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07037004·Phase 2·Recruiting·Listed Jun 2025

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Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

for Differentiated Thyroid Cancer

Sites in San Francisco +3 more locations

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: 2 - 25

Code: NCT06458036·Phase 2·Recruiting·Listed Jun 2024

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Abemaciclib Before 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer

for Castration-Resistant Prostate Carcinoma

1 location in San Francisco

Sponsor: Vadim S Koshkin

Sex: All·Age: 18+

Code: NCT05113537·Phase 1, Phase 2·Recruiting·Listed Nov 2021

Apply to this trial