Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Menopausal HT for Women Living With HIV (HoT)

for HIV Infection

Sites in Los Angeles, San Francisco +21 more locations

Sponsor: Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

Sex: Female·Age: 40 - 60

Code: NCT06856174·Phase 4·Recruiting·Listed Mar 2025

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Intermittent Fasting on Body Fat and Quality of Life

for Healthy

1 location in Loma Linda

Sponsor: Loma Linda University

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06307275·Recruiting·Listed Mar 2024

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Positive Affect Treatment for Adolescents With Early Life Adversity

for Depression

1 location in Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 12 - 16·Accepts healthy volunteers

Code: NCT06273137·Recruiting·Listed Feb 2024

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Treating Anemia in Myelofibrosis With Repurposed Drugs (Nelfinavir) That Restore Iron Delivery to the Bone Marrow

for Myelofibrosis

1 location in Orange

Sponsor: University of California, Irvine

Sex: All·Age: 18+

Code: NCT07281781·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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Precise Infliximab Exposure and Pharmacodynamic Control

for Crohn Disease

Sites in Los Angeles, San Diego +9 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 6 - 22

Code: NCT05660746·Phase 2, Phase 3·Recruiting·Listed Dec 2022

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Maintenance rTMS for Depression (Maitr-De)

for Major Depressive Disorder

Sites in San Diego +1 more location

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 80

Code: NCT06938841·Recruiting·Listed Apr 2025

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Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

Sites in Los Angeles, Beverly Hills +17 more locations

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting·Listed Jul 2023

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Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Cemiplimab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06860815·Phase 2·Recruiting·Listed Mar 2025

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Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

for Chronic Graft Versus Host Disease

Sites in Duarte +4 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05996627·Phase 2·Recruiting·Listed Aug 2023

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LPFC Organization in Emotion-Duration Difference Estimation

for Healthy

1 location in Santa Barbara

Sponsor: University of California, Santa Barbara

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT06276400·Recruiting·Listed Feb 2024

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Personalized Escalation of Consolidation Treatment Following Chemoradiotherapy and Immunotherapy in Stage III NSCLC in Stage III NSCLC

for Non Small Cell Lung Cancer

1 location in Stanford

Sponsor: Maximilian Diehn

Sex: All·Age: 18+

Code: NCT04585490·Phase 3·Recruiting·Listed Oct 2020

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Stanford Pragmatic Effectiveness Comparison

for Chronic Pain

1 location in Redwood City

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT04441034·Phase 4·Recruiting·Listed Jun 2020

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Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

for Borderline Resectable Pancreatic Adenocarcinoma

1 location in Los Angeles

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05688215·Phase 1, Phase 2·Recruiting·Listed Jan 2023

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Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

for LAMA2-MD \(Merosin Deficient Congenital Muscular Dystrophy, MDC1A\)

Sites in Los Angeles, Stanford +12 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 5

Code: NCT06503367·Recruiting·Listed Jul 2024

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Los Angeles, San Francisco +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

Sites in Duarte +8 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting·Listed Dec 2021

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A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate

for Prostate Cancer (Adenocarcinoma)

Sites in Duarte +6 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 18+

Code: NCT06844383·Phase 2·Recruiting·Listed Feb 2025

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Multisite Implementation of COMPRENDO

for Pediatric Cancer

Sites in San Francisco, San Diego +2 more locations

Sponsor: University of California, San Diego

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06055296·Recruiting·Listed Sep 2023

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ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

for Corneal Transplant Failure

Sites in Los Angeles, San Francisco +10 more locations

Sponsor: Massachusetts Eye and Ear Infirmary

Sex: All·Age: 18+

Code: NCT06753916·Phase 2·Recruiting·Listed Dec 2024

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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

for Type2Diabetes

Sites in Los Angeles +35 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 40 - 80

Code: NCT05390892·Phase 4·Recruiting·Listed May 2022

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Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors

for Advanced Solid Tumor

1 location in San Francisco

Sponsor: Robert Bok, MD, PhD

Sex: All·Age: 18+

Code: NCT05599048·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03728335·Phase 2·Recruiting·Listed Nov 2018

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Normal-weight Diabetes: Adipocyte-directed Therapy With Pioglitazone or Tirzepatide

for Diabetes Mellitus, Type 2

Drug: Tirzepatide

Sites in Palo Alto & Stanford

Sponsor: Stanford University

Sex: All·Age: 30 - 70·Accepts healthy volunteers

Code: NCT06657209·Phase 4·Recruiting·Listed Oct 2024

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A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy

for Recurrent Childhood Acute Myeloid Leukemia

Sites in San Francisco, Orange +17 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 18

Code: NCT06247787·Phase 1·Recruiting·Listed Feb 2024

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Assessing Improvements in Mood and Sleep Trial

for Depression

Sites in Los Angeles +2 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 55+

Code: NCT06639477·Recruiting·Listed Oct 2024

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A2-ESO-1 TCR-Engineered T Cells for Relapsed/Refractory Advanced or Metastatic NY-ESO-1 Overexpression Positive Triple Negative Breast Cancer

for Triple Negative Breast Cancer

1 location in Los Angeles

Sponsor: University of Southern California

Sex: Female·Age: 18+

Code: NCT05989828·Phase 1·Recruiting·Listed Aug 2023

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Tarlatamab in Advanced Delta-like 3 (DLL3)-Expressing Tumors Including Neuroendocrine Neoplasms

for DLL3-expressing Tumors

Drug: Tarlatamab

Sites in Los Angeles, San Francisco +3 more locations

Sponsor: Jonsson Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT06788938·Phase 2·Recruiting·Listed Jan 2025

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Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

for Neurofibromatosis 1

Drug: Selumetinib

Sites in Los Angeles, Palo Alto +13 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 1 - 8

Code: NCT06188741·Phase 2·Recruiting·Listed Jan 2024

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Adjuvant Hypofractionated Stereotactic Radiosurgery for Intermediate-risk Meningioma

for Meningioma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06557512·Recruiting·Listed Aug 2024

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06287944·Phase 1·Recruiting·Listed Mar 2024

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Hyperpolarized Pyruvate (13C) MR Imaging in Monitoring Patients With Prostate Cancer on Active Surveillance

for Prostate Adenocarcinoma

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT03933670·Phase 2·Recruiting·Listed May 2019

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Milk-Tot Study: Impact of Whole Versus Low-fat Milk on Child Health

for Obesity

1 location in Oakland

Sponsor: University of California, Davis

Sex: All·Age: 23 Months - 48 Months·Accepts healthy volunteers

Code: NCT06230510·Recruiting·Listed Jan 2024

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Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

for Preterm Delivery

Sites in San Francisco +13 more locations

Sponsor: The George Washington University Biostatistics Center

Sex: Female·Age: 14+·Accepts healthy volunteers

Code: NCT06980025·Phase 3·Recruiting·Listed May 2025

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Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab

for Hepatocellular Carcinoma

Drug: Tremelimumab

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18+

Code: NCT06710223·Phase 1·Recruiting·Listed Nov 2024

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Single Versus Dual Implant Fixation of Distal Femur Fractures

for Articular Fractures

Sites in Los Angeles +15 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06286670·Recruiting·Listed Feb 2024

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Care in Multiple Sclerosis (MS)

for Multiple Sclerosis

Sites in San Francisco +5 more locations

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT07011914·Recruiting·Listed Jun 2025

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Platform of Randomized Adaptive Clinical Trials in Critical Illness

for Respiratory Insufficiency

Sites in Los Angeles, San Francisco +24 more locations

Sponsor: University Health Network, Toronto

Sex: All·Age: 18+

Code: NCT05440851·Recruiting·Listed Jul 2022

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Campath/Fludarabine/Melphalan Transplant Conditioning for Non-Malignant Diseases

for Metabolic Disorders

Sites in San Diego, Orange +10 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: Up to 20

Code: NCT00920972·Phase 1, Phase 2·Recruiting·Listed Jun 2009

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Food is Medicine Prospective Study

for Wounds and Injuries

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 18+

Code: NCT07169448·Recruiting·Listed Sep 2025

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Brain Mechanisms Supporting Cannabis-induced Pain Relief

for Sciatica

1 location in La Jolla

Sponsor: University of California, San Diego

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT04982965·EARLY_Phase 1·Recruiting·Listed Jul 2021

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