Paid Clinical Trials in California

California has 6,384 paid clinical trials enrolling now across cities including Los Angeles, San Francisco and San Diego. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in California include Stanford Medicine, UCLA Health and UCSF, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 25, 2026.

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5,286 clinical trials

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Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Drug: Sonrotoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06859008·Phase 1·Recruiting·Listed Mar 2025

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Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Venetoclax

Sites in Duarte +3 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03523975·Phase 1, Phase 2·Recruiting·Listed May 2018

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The Peri-OPerative COlchicine to Reduce Negative Events (POPCORN) Trial

for Coronary Artery Disease

Sites in Long Beach +8 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05618353·Phase 4·Recruiting·Listed Nov 2022

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Reactive Driven Support for Treatment, Adherence, Resilience, and Thriving (reSTART) Clinical Trial

for Behavioral Intervention

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18 - 70

Code: NCT07125235·Recruiting·Listed Aug 2025

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SDM POSSIBLE: A Breast Cancer Treatment Decision Aid for Women 70+ With Low-Risk Stage I Breast Cancers

for Breast Cancer

Sites in Los Angeles +10 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06896474·Recruiting·Listed Mar 2025

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Los Angeles, San Diego +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Better Breaks: Strength Breaks vs Walk Breaks for Sedentary Behavior Breaks

for Sedentary Employees

1 location in Palo Alto

Sponsor: Stanford University

Sex: All·Age: 30+·Accepts healthy volunteers

Code: NCT06909097·Recruiting·Listed Apr 2025

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Transcranial Photobiomodulation (tPBM) in Alzheimer's Disease Study

for Alzheimer's Disease

1 location in Los Angeles

Sponsor: Cedars-Sinai Medical Center

Sex: All·Age: 55 - 89

Code: NCT07224607·Recruiting·Listed Nov 2025

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A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

for Acute HIV Infection

Sites in Los Angeles, San Francisco +30 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 70

Code: NCT05719441·Phase 2·Recruiting·Listed Feb 2023

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Brief Behavioral Treatment for Insomnia in Veterans With Posttraumatic Stress Disorder

for Posttraumatic Stress Disorder

1 location in San Francisco

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT05780177·Recruiting·Listed Mar 2023

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Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617

for Prostate Cancer

1 location in San Francisco

Sponsor: Thomas Hope

Sex: Male·Age: 18+

Code: NCT07054346·Phase 1·Recruiting·Listed Jul 2025

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Efficacy of Rifaximin With NAC in IBS-D

for IBS (Irritable Bowel Syndrome)

1 location in Los Angeles

Sponsor: Mark Pimentel, MD

Sex: All·Age: 18+

Code: NCT06727422·Phase 2·Recruiting·Listed Dec 2024

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Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services

for Autism Spectrum Disorder

Sites in San Diego +1 more location

Sponsor: San Diego State University

Sex: All·Age: 6 - 99·Accepts healthy volunteers

Code: NCT06651086·Recruiting·Listed Oct 2024

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Reinvigorating TNBC Response to Immunotherapy With Combination Myeloid Inhibition and Radiation

for TNBC - Triple-Negative Breast Cancer

1 location in Los Angeles

Sponsor: Stephen Shiao

Sex: Female·Age: 18+

Code: NCT05491226·Phase 2·Recruiting·Listed Aug 2022

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The da Vinci Single Port Robotic System for Use in Abdominal and Pelvic Surgical Procedures

for Disease or Disorder

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672368·Phase 2·Recruiting·Listed Jan 2023

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Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for Metastatic Small Intestinal Adenocarcinoma

Sites in Los Angeles, San Diego +397 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04205968·Phase 2·Recruiting·Listed Dec 2019

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Real-Time Diagnosis of Life-Threatening Necrotizing Soft Tissue Infections (NSTI) Using Indocyanine Green (ICG) Kinetic Modeling

for Necrotizing Fascitis

Sites in Los Angeles, Stanford +6 more locations

Sponsor: Eric R. Henderson

Sex: All·Age: 18+

Code: NCT06877793·Recruiting·Listed Mar 2025

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Neural Bases of Vocal Sensorimotor Impairment in Aphasia

for Aphasia

Sites in Irvine +2 more locations

Sponsor: The University of Texas at Dallas

Sex: All·Age: 21 - 75·Accepts healthy volunteers

Code: NCT04742894·Recruiting·Listed Feb 2021

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Language Control Across Modalities

for Healthy

1 location in San Diego

Sponsor: University of California, San Diego

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07226921·Recruiting·Listed Nov 2025

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Women Focused Encounters for Resilience Independence Strength and Eudaimonia

for HIV Infections

1 location in San Diego

Sponsor: University of California, San Diego

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06216600·Recruiting·Listed Jan 2024

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Maralixibat in Patients With Cystic Fibrosis and Constipation

for Constipation Chronic Idiopathic

1 location in Los Angeles

Sponsor: Children's Hospital Los Angeles

Sex: All·Age: 1 - 18

Code: NCT06413368·Phase 2, Phase 3·Recruiting·Listed May 2024

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Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

for Urologic Diseases

Sites in San Francisco +1 more location

Sponsor: Wake Forest University Health Sciences

Sex: Male·Age: 21 - 75

Code: NCT03258658·Phase 1·Recruiting·Listed Aug 2017

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Wearable Activity Tracking to Curb Hospitalizations

for Hematopoietic Neoplasm

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06587100·Recruiting·Listed Sep 2024

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Glaucoma Screening to Enhance At-Risk Californians' Health

for Glaucoma

Sites in San Francisco & Oakland

Sponsor: University of California, San Francisco

Sex: All·Age: 50+·Accepts healthy volunteers

Code: NCT06854198·Recruiting·Listed Mar 2025

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Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

for Castrate Resistant Prostate Cancer

1 location in San Francisco

Sponsor: University of California, San Francisco

Sex: Male·Age: 18+

Code: NCT05766371·Phase 2·Recruiting·Listed Mar 2023

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Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 65+

Code: NCT06042569·Phase 2·Recruiting·Listed Sep 2023

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DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma

for High Grade Glioma

Sites in Los Angeles, San Francisco +3 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06504381·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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My Life and My Experiences Project

for Stress and Memory in Adolescence

1 location in Irvine

Sponsor: University of California, Irvine

Sex: All·Age: 12 - 18·Accepts healthy volunteers

Code: NCT06821178·Recruiting·Listed Feb 2025

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Study of Personalized Cancer Therapy to Determine Response and Toxicity

for Cancer

Sites in San Diego, La Jolla & Rancho Mirage

Sponsor: Shu Mei Kato

Sex: All·Age: 7+

Code: NCT02478931·Recruiting·Listed Jun 2015

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A Primary Care Based Intervention to Prevent Childhood Obesity Among Low-income Latino Children

for Obesity, Childhood

Sites in San Francisco & Sunnyvale

Sponsor: University of California, San Francisco

Sex: All·Age: 7 Days - 2 Months

Code: NCT06398509·Recruiting·Listed May 2024

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HIFU for Focal Ablation of Prostate Tissue: An Observational Study

for Prostate Cancer

1 location in Los Angeles

Sponsor: University of California, Los Angeles

Sex: Male·Age: 40 - 85

Code: NCT03620786·Recruiting·Listed Aug 2018

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Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell Disease

for Sickle Cell Disease

Sites in Los Angeles & Oakland

Sponsor: Mark Walters, MD

Sex: All·Age: 12 - 35

Code: NCT04774536·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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Levonorgestrel 52 mg IUD for Emergency Contraception and Same-Day Start

for Contraception

Sites in San Jose +6 more locations

Sponsor: University of Utah

Sex: Female·Age: 16 - 35

Code: NCT05444582·Phase 4·Recruiting·Listed Jul 2022

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Prehospital Analgesia INtervention Trial (PAIN)

for Traumatic Injury

Sites in San Francisco, San Diego +8 more locations

Sponsor: Jason Sperry

Sex: All·Age: 18+

Code: NCT05437575·Phase 3·Recruiting·Listed Jun 2022

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The Effects of Patient and Visit Characteristics on Health Outcomes in Knee Osteoarthritis

for Knee Osteoarthritis

1 location in Sacramento

Sponsor: University of California, Davis

Sex: All·Age: 50+

Code: NCT06574191·Recruiting·Listed Aug 2024

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CMV CTLs in Neonates With CMV Infection

for Congenital Cytomegaloviral (CMV) Disease

Sites in Los Angeles +3 more locations

Sponsor: New York Medical College

Sex: All·Age: 0 Days - 21 Days

Code: NCT05564598·Phase 2·Recruiting·Listed Oct 2022

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Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients

for Metastatic Castration-resistant Prostate Cancer (mCRPC)

1 location in Los Angeles

Sponsor: Charles Drew University of Medicine and Science

Sex: Male·Age: 18+

Code: NCT06615752·Phase 1, Phase 2·Recruiting·Listed Sep 2024

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Development, Attention, and Inhibition Study

for The Ability to Delay Gratification

1 location in Davis

Sponsor: University of California, Davis

Sex: All·Age: 4 - 7·Accepts healthy volunteers

Code: NCT06605001·Recruiting·Listed Sep 2024

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Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma

for Childhood Fibrolamellar Carcinoma

Sites in Los Angeles, San Francisco +19 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 39

Code: NCT06620302·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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TB006 for Autism Spectrum Disorder

for Autism Spectrum Disorder

Sites in Aliso Viejo +1 more location

Sponsor: Rossignol Medical Center

Sex: All·Age: 18 - 35

Code: NCT06500637·Phase 2·Recruiting·Listed Jul 2024

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