Paid Clinical Trials in Charleston, SC

As of July 2026, 683 paid clinical trials are recruiting in Charleston, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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608 clinical trials

An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH

for Pulmonary Hypertension

Sites in Charleston +7 more locations

Sponsor: Liquidia Technologies, Inc.

Sex: All·Age: 18 - 80

Code: NCT06129240·Recruiting·Listed Nov 2023

Apply to this trial

A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment

for Primary Biliary Cholangitis

Drug: Elafibranor

Sites in Charleston +18 more locations

Sponsor: Ipsen

Sex: All·Age: All ages

Code: NCT06447168·Recruiting·Listed Jun 2024

Apply to this trial

4D-710 in Adult Patients With Cystic Fibrosis

for Cystic Fibrosis Lung

Sites in Charleston +17 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 18+

Code: NCT05248230·Phase 2·Recruiting·Listed Feb 2022

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A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema

for Eczema

Sites in Charleston, Greenville +9 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT06807268·Phase 3·Recruiting·Listed Feb 2025

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A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

for Colitis Ulcerative

Drug: SAR441566

Sites in Charleston +18 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06867094·Phase 2·Recruiting·Listed Mar 2025

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A Study to Compare the Efficacy and Safety of BMS-986393 Versus Standard Regimens in Adult Participants With Relapsed or Refractory and Lenalidomide-exposed Multiple Myeloma (QUINTESSENTIAL-2)

for Relapsed or Refractory Multiple Myeloma (RRMM)

Sites in Charleston +19 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06615479·Phase 3·Recruiting·Listed Sep 2024

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A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Crohn's Disease.

for Crohn's Disease

Drug: SAR441566

Sites in Charleston +18 more locations

Sponsor: Sanofi

Sex: All·Age: 18 - 75

Code: NCT06637631·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

A Study of Modified Release RTN-001 In Patients With Uncontrolled Hypertension

for Uncontrolled Hypertension

Sites in Charleston +21 more locations

Sponsor: Retension Pharmaceuticals. Inc.

Sex: All·Age: 18 - 70

Code: NCT07142356·Phase 2·Recruiting·Listed Aug 2025

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A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Charleston +16 more locations

Sponsor: Rein Therapeutics

Sex: All·Age: 40+

Code: NCT06968845·Phase 2·Recruiting·Listed May 2025

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Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

for Atrial Fibrillation (AF)

Sites in Charleston +17 more locations

Sponsor: Arga Medtech SA

Sex: All·Age: 18 - 80

Code: NCT06784466·Recruiting·Listed Jan 2025

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Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)

for Treatment Resistant Depression

Sites in Charleston +23 more locations

Sponsor: Abbott Medical Devices

Sex: All·Age: 22 - 70

Code: NCT06423430·Recruiting·Listed May 2024

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

Sites in Charleston, Greenville +11 more locations

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 74

Code: NCT07085104·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

A Long-Term Extension Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis (UC) or Crohn's Disease (CD)

for Ulcerative Colitis

Sites in Charleston +13 more locations

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT06405087·Phase 3·Recruiting·Listed May 2024

Apply to this trial

Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for NSCLC Stage IV

Sites in Charleston +16 more locations

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 90

Code: NCT06745908·Phase 3·Recruiting·Listed Dec 2024

Apply to this trial

PULSED AF Post-Approval Study

for Atrial Fibrillation

Sites in Charleston, Anderson +15 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18+

Code: NCT06578104·Recruiting·Listed Aug 2024

Apply to this trial

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Charleston +13 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18 - 89

Code: NCT06253130·Phase 1, Phase 2·Recruiting·Listed Feb 2024

Apply to this trial

Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

for Regional Citrate Anticoagulation (RCA)

Sites in Charleston +7 more locations

Sponsor: Vantive Health LLC

Sex: All·Age: 18+

Code: NCT05399537·Phase 3·Recruiting·Listed Jun 2022

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A Study of ZL-1310 in Subjects With Small Cell Lung Cancer

for SCLC

Sites in Charleston +10 more locations

Sponsor: Zai Lab (Shanghai) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06179069·Phase 1·Recruiting·Listed Dec 2023

Apply to this trial

This Study Will Evaluate the Effectiveness of NTX-001, a Surgical Nerve Repair Product When Used in People With Upper Extremity Nerve Lacerations.

for Peripheral Nerve Injury Upper Limb

Sites in Charleston +23 more locations

Sponsor: Neuraptive Therapeutics Inc.

Sex: All·Age: 18 - 80

Code: NCT06616025·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

WRAP North America

for Venous Stenosis

Sites in Charleston, Orangeburg +13 more locations

Sponsor: Merit Medical Systems, Inc.

Sex: All·Age: 18+

Code: NCT06807099·Recruiting·Listed Feb 2025

Apply to this trial

Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis

for Cystic Fibrosis

Sites in Charleston +11 more locations

Sponsor: Arcturus Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06747858·Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

for Insomnia

Sites in Charleston +10 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18 - 70

Code: NCT06655883·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

A Long-Term Study to Learn About The Study Medicine Called Ritlecitinib in Children With Severe Alopecia Areata.

for Severe Alopecia Areata

Drug: Ritlecitinib

Sites in Charleston +17 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 14

Code: NCT07029828·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

for Solid Tumors

Sites in Charleston +14 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT06953089·Phase 2·Recruiting·Listed May 2025

Apply to this trial

A Study of Vonicog Alfa (rVWF) in Children With Severe Von Willebrand Disease (vWD)

for Von Willebrand Disease (VWD)

Sites in Charleston +10 more locations

Sponsor: Takeda

Sex: All·Age: Up to 17

Code: NCT05582993·Phase 3·Recruiting·Listed Oct 2022

Apply to this trial

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

for Myelodysplastic Syndromes

Drug: Venetoclax

Sites in Charleston +21 more locations

Sponsor: Taiho Oncology, Inc.

Sex: All·Age: 18+

Code: NCT04256317·Phase 2, Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Charleston +18 more locations

Sponsor: Cabaletta Bio

Sex: All·Age: 18 - 65

Code: NCT06121297·Phase 1, Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF

for Heart Failure With Preserved Ejection Fraction (HFpEF

Sites in Charleston +12 more locations

Sponsor: Axon Therapies, Inc.

Sex: All·Age: 40+

Code: NCT04592445·Recruiting·Listed Oct 2020

Apply to this trial

Clinical Safety and Efficacy of the VDyne Transcatheter Tricuspid Valve Replacement System for the Treatment of Tricuspid Regurgitation ( VISTA-US)

for Tricuspid Regurgitation

Sites in Charleston +9 more locations

Sponsor: VDyne, Inc.

Sex: All·Age: 18+

Code: NCT05848284·Recruiting·Listed May 2023

Apply to this trial

Helix Research Network

for Genetic Predisposition to Disease

Sites in Charleston +13 more locations

Sponsor: Helix, Inc

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06057181·Recruiting·Listed Sep 2023

Apply to this trial

Cryoablation for Monomorphic Ventricular Tachycardia

for Sustained VT

Sites in Charleston +12 more locations

Sponsor: Adagio Medical

Sex: All·Age: 18+

Code: NCT05675865·Recruiting·Listed Jan 2023

Apply to this trial

A Non-interventional, Post-authorisation Safety Study of Patients Treated With Efgartigimod Alfa

for Myasthenia Gravis

Sites in Charleston +16 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06298565·Recruiting·Listed Mar 2024

Apply to this trial

A Dose Escalation Study of AV-380 in Cancer Patients With Cachexia

for Cachexia

Sites in Charleston +11 more locations

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05865535·Phase 1·Recruiting·Listed May 2023

Apply to this trial

A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions

for Narcolepsy Type 1

Sites in Charleston, Columbia +17 more locations

Sponsor: Takeda

Sex: All·Age: 16 - 70

Code: NCT05816382·Phase 2, Phase 3·Recruiting·Listed Apr 2023

Apply to this trial

A Study of Nipocalimab Administered to Adults With Generalized Myasthenia Gravis

for Myasthenia Gravis

Drug: Nipocalimab

Sites in Charleston +10 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04951622·Phase 3·Recruiting·Listed Jul 2021

Apply to this trial

VALOR: Vaginal Atrophy & Long-term Observation of Recovery

for Atrophic Vaginitis

Sites in Charleston, West Columbia +11 more locations

Sponsor: Stratpharma AG

Sex: Female·Age: 18+

Code: NCT05953090·Recruiting·Listed Jul 2023

Apply to this trial

Melodi Matrix™ in Breast Reconstruction

for Breast Reconstruction

Sites in Charleston +9 more locations

Sponsor: Melodi Health, Inc.

Sex: Female·Age: 22+

Code: NCT06027996·Recruiting·Listed Sep 2023

Apply to this trial

Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

Sites in Charleston, Greenville +22 more locations

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting·Listed Nov 2022

Apply to this trial

Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

for Head and Neck Squamous Cell Carcinoma

Sites in Charleston +14 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT04429542·Phase 1·Recruiting·Listed Jun 2020

Apply to this trial

(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis

for Advanced Systemic Mastocytosis (AdvSM)

Sites in Charleston +8 more locations

Sponsor: Cogent Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT04996875·Phase 2·Recruiting·Listed Aug 2021

Apply to this trial