Oncology Clinical Trials in Cincinnati, OH

As of September 2026, 179 paid clinical trials are recruiting for Oncology in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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179 clinical trials for Oncology

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Clinical Utility of Management of Patients With Pulmonary Nodules Using the Percepta Nasal Swab Classifier

for Pulmonary Nodule, Solitary

Sites in Cincinnati, Toledo +20 more locations

Sponsor: Veracyte, Inc.

Sex: All·Age: 29 - 85

Code: NCT06426628·Recruiting·Listed May 2024

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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for Multiple Myeloma

Sites in Cincinnati +8 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07555938·Phase 3·Recruiting·Listed Apr 2026

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A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for Colorectal Cancer

Sites in Cincinnati +4 more locations

Sponsor: Dispatch Biotherapeutics

Sex: All·Age: 18+

Code: NCT07544589·Phase 1·Recruiting·Listed Apr 2026

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A Study to Access Intravenous (IV) Telisotuzumab Adizutecan in Combination With IV Bevacizumab Compared to Standard of Care IV Bevacizumabin Combination With Oral Trifluridine and Tipiracil in Adult Participants With Refractory Metastatic Colorectal Cancer

for Colorectal Cancer

Drug: Bevacizumab

Sites in Cincinnati +16 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07525206·Phase 3·Recruiting·Listed Apr 2026

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A Phase III Trial of BNT324 Versus Docetaxel in Metastatic Castration-resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Cincinnati +16 more locations

Sponsor: BioNTech SE

Sex: Male·Age: 18+

Code: NCT07365995·Phase 3·Recruiting·Listed Jan 2026

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A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)

for Bladder Cancer

Sites in Cincinnati +11 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07419295·Phase 3·Recruiting·Listed Feb 2026

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A Study of Pirtobrutinib (LY3527727) in Participants With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

for Chronic Lymphocytic Leukemia

Sites in Cincinnati +8 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07218341·Phase 4·Recruiting·Listed Oct 2025

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FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

for Ovarian Cancer

Sites in Cincinnati, Columbus +18 more locations

Sponsor: Tubulis GmbH

Sex: All·Age: 18+

Code: NCT06303505·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Study of Trastuzumab Deruxtecan Versus Standard of Care Chemotherapy for HER2-Expressing (IHC 3+/2+) Endometrial Cancer

for Endometrial Cancer

Sites in Cincinnati +9 more locations

Sponsor: Daiichi Sankyo

Sex: Female·Age: 18+

Code: NCT07022483·Phase 3·Recruiting·Listed Jun 2025

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A Study of DB-1324 in Advanced/Metastatic Gastrointestinal Tumors

for Gastrointestinal Cancer

Sites in Cincinnati +3 more locations

Sponsor: DualityBio Inc.

Sex: All·Age: 18+

Code: NCT07263594·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for Multiple Myeloma

Sites in Cincinnati, Columbus +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06892522·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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A Study to Assess Change in Disease Activity and Adverse Events in Adult Participants With Gynecologic Cancers Receiving Intravenous Infusion of IMGN151 as Monotherapy or in Combination With Other Therapies

for Gynecologic Cancers

Sites in Cincinnati +7 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT07024784·Phase 2·Recruiting·Listed Jun 2025

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Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

for Non Hodgkin Lymphoma

Sites in Cincinnati, Columbus +6 more locations

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 13+

Code: NCT04771572·Phase 1·Recruiting·Listed Feb 2021

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Study of Oral Administration of LP-168 in Patients With Relapsed or Refractory B-cell Malignancies.

for CLL/SLL

Sites in Cincinnati, Columbus +2 more locations

Sponsor: Newave Pharmaceutical Inc

Sex: All·Age: 18+

Code: NCT04775745·Phase 1·Recruiting·Listed Mar 2021

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A Study of LM-24C5 For Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Cincinnati +5 more locations

Sponsor: LaNova Medicines Limited

Sex: All·Age: 18+

Code: NCT06187402·Phase 1, Phase 2·Recruiting·Listed Jan 2024

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64Cu-LNTH-1363S in Patients With Sarcoma or Gastrointestinal Tract Cancer

for Metastatic Sarcoma

Sites in Cincinnati +4 more locations

Sponsor: Lantheus Medical Imaging

Sex: All·Age: 15+

Code: NCT06298916·Phase 1, Phase 2·Recruiting·Listed Mar 2024

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Pan-RAS Inhibitor YL-17231 in Patients With Advanced Solid Tumors Harboring Mutations in KRAS, HRAS, or NRAS

for Advanced Solid Tumors

Sites in Cincinnati +2 more locations

Sponsor: Shanghai YingLi Pharmaceutical Co. Ltd.

Sex: All·Age: 18+

Code: NCT06096974·Phase 1·Recruiting·Listed Oct 2023

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Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Cincinnati, Canton +2 more locations

Sponsor: Telios Pharma, Inc.

Sex: All·Age: 18+

Code: NCT05280509·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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Study of VIP943 in Subjects With Advanced CD123+ Hematologic Malignancies

for Acute Myeloid Leukemia

Sites in Cincinnati +4 more locations

Sponsor: Vincerx Pharma, Inc.

Sex: All·Age: 18+

Code: NCT06034275·Phase 1·Recruiting·Listed Sep 2023

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Haploidentical Donor Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Neuroblastoma

for Neuroblastoma

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT07635056·Phase 2·Recruiting·Listed Jun 2026

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Intraoperative Neuromonitoring (IONM) and Bipolar Electrocautery (BE) During Axillary Lymph Node Dissection (ALND)

for Breast Cancer

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18 - 70

Code: NCT07528638·Recruiting·Listed Apr 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Cincinnati, Franklin +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

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Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

for Head and Neck Squamous Cell Carcinoma

Sites in Cincinnati, West Chester +461 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT02734537·Phase 2·Recruiting·Listed Apr 2016

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

Sites in Cincinnati, Franklin +612 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

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Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

for Advanced Malignant Solid Neoplasm

Sites in Cincinnati, Franklin +427 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: All ages

Code: NCT05564377·Phase 2·Recruiting·Listed Oct 2022

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TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

for Lymphoma, Non-Hodgkin

Sites in Cincinnati, West Chester +144 more locations

Sponsor: American Society of Clinical Oncology

Sex: All·Age: 12+

Code: NCT02693535·Phase 2·Recruiting·Listed Feb 2016

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

Sites in Cincinnati, Franklin +301 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting·Listed Aug 2020

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Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Trial

for Metastatic Renal Cell Carcinoma

Sites in Cincinnati, West Chester +278 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05327686·Phase 2·Recruiting·Listed Apr 2022

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Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

for Fallopian Tube Endometrioid Adenocarcinoma

Drug: Bevacizumab

Sites in Cincinnati, Dublin +653 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06580314·Phase 3·Recruiting·Listed Aug 2024

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

Sites in Cincinnati, Columbus +276 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting·Listed Jun 2020

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Cincinnati, West Chester +479 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

Sites in Cincinnati, Dayton +170 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 6 Months - 21

Code: NCT04293562·Phase 3·Recruiting·Listed Mar 2020

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E-Mindfulness Approaches for Living After Breast Cancer

for Breast Cancer

Sites in Cincinnati, West Chester +372 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18 - 50

Code: NCT06748222·Phase 3·Recruiting·Listed Dec 2024

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Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

for Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in Cincinnati, West Chester +144 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT06532279·Phase 2·Recruiting·Listed Aug 2024

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Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

for High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements

Sites in Cincinnati, West Chester +80 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06649812·Phase 2·Recruiting·Listed Oct 2024

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

Sites in Cincinnati, Dayton +185 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting·Listed May 2019

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Early Pelvic Floor Physical Therapy for Women Undergoing Pelvic Radiation for Gynecologic Malignancies

for Cervical Cancer

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: Female·Age: 18+

Code: NCT07447895·Recruiting·Listed Mar 2026

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Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

for Ganglioneuroblastoma, Nodular

Sites in Cincinnati, Dayton +152 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 30

Code: NCT06172296·Phase 3·Recruiting·Listed Dec 2023

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Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Cincinnati, Dayton +225 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Trastuzumab Deruxtecan (DS-8201a) for the Treatment of Recurrent or Refractory Osteosarcoma, Wilms Tumor, and Desmoplastic Small Round Cell Tumor

for Desmoplastic Small Round Cell Tumor

Sites in Cincinnati +17 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 12 - 39

Code: NCT04616560·Phase 2·Recruiting·Listed Nov 2020

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Conditions in Oncology (Cincinnati, OH)

Solid tumor· 24 Non-small cell lung cancer (NSCLC)· 23 Breast cancer· 14 Acute myeloid leukemia (AML)· 13 Multiple myeloma· 11 Colorectal cancer· 10 Ovarian cancer· 10 Prostate cancer· 9 Non-Hodgkin lymphoma· 9 Endometrial cancer· 8 Chronic lymphocytic leukemia (CLL)· 8 Melanoma· 8 Cancer (any)· 8 Glioma· 7 Diffuse large B-cell lymphoma (DLBCL)· 7 Head and neck cancer· 7 Neuroblastoma· 7 Pancreatic cancer· 6 Leukemia (other)· 6 Hematologic malignancy· 6 Metastatic prostate cancer· 5 Glioblastoma· 5 Small lymphocytic lymphoma· 5 Myelofibrosis· 4 Osteosarcoma· 4 Triple-negative breast cancer· 3 Small cell lung cancer· 3 Gastric cancer· 3 Esophageal cancer· 3 Bladder cancer· 3 Fallopian tube cancer· 3 Brain cancer· 3 Myeloproliferative neoplasm· 3 Hodgkin lymphoma· 3 Follicular lymphoma· 3 Sarcoma· 3 Lung cancer· 2 Metastatic colorectal cancer· 2 Gastroesophageal junction cancer· 2 Biliary tract cancer· 2 Gastrointestinal cancer· 2 Kidney cancer· 2 Cervical cancer· 2 Acute lymphoblastic leukemia· 2 Myelodysplastic syndromes (MDS)· 2 Mantle cell lymphoma· 2 Marginal zone lymphoma· 2 Ewing sarcoma· 2 Metastatic breast cancer· 1 Rectal cancer· 1 Liver cancer· 1 Burkitt lymphoma· 1 Rhabdomyosarcoma· 1 Neuroendocrine tumors· 1