Oncology Clinical Trials in Cincinnati, OH

As of September 2026, 179 paid clinical trials are recruiting for Oncology in Cincinnati, Ohio. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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179 clinical trials for Oncology

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Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Sites in Cincinnati, Columbus +9 more locations

Sponsor: Stichting Hemato-Oncologie voor Volwassenen Nederland

Sex: All·Age: 18+

Code: NCT07223814·Phase 3·Recruiting·Listed Nov 2025

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

for Acute Lymphoblastic Leukemia

Sites in Cincinnati, Dayton +154 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: Up to 22

Code: NCT04726241·Phase 1, Phase 2·Recruiting·Listed Jan 2021

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Cincinnati, Dayton +200 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

for Ganglioneuroblastoma

Sites in Cincinnati, Dayton +141 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 30

Code: NCT03126916·Phase 3·Recruiting·Listed Apr 2017

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Testing the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable Cancers

for Metastatic Colorectal Carcinoma

Sites in Cincinnati, West Chester +13 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05803382·Phase 1·Recruiting·Listed Apr 2023

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Targeted Pediatric High-Grade Glioma Therapy

for High Grade Glioma

Sites in Cincinnati, Columbus +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05839379·Recruiting·Listed May 2023

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Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

for Head and Neck Squamous Cell Carcinoma

Drug: Cemiplimab

Sites in Cincinnati, West Chester +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06980038·Phase 2·Recruiting·Listed May 2025

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A Phase 1b Study of Menin Inhibitor SNDX- 5613 in Combination With Daunorubicin and Cytarabine in Newly Diagnosed Patients With Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype or MLL/KMT2A Rearranged or NUP98 Alterations Disease

for Acute Myeloid Leukemia

Sites in Cincinnati, West Chester +19 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 75

Code: NCT05886049·Phase 1·Recruiting·Listed Jun 2023

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PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

for High Grade Glioma

Sites in Cincinnati, Columbus +11 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 3 - 39

Code: NCT05096481·Phase 2·Recruiting·Listed Oct 2021

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A Study to Find the Highest Dose of Cedazuridine and Decitabine Combination With Filgrastim as a Treatment Option After Hematopoietic Stem Cell Transplant in Children With High-Risk Acute Myeloid Leukemia

for Acute Myeloid Leukemia Post Cytotoxic Therapy

Sites in Cincinnati +11 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: Up to 21

Code: NCT07012044·Phase 1·Recruiting·Listed Jun 2025

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Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

for Refractory Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Cincinnati +9 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: 1 - 30

Code: NCT06177067·Phase 1·Recruiting·Listed Dec 2023

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A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Cincinnati, Columbus +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

for Colorectal Carcinoma

Sites in Cincinnati +18 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 12 Months - 30

Code: NCT04851119·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

Sites in Cincinnati, West Chester +101 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting·Listed Jan 2024

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Lutathera for Treatment of Recurrent or Progressive High-Grade CNS Tumors

for High Grade Glioma

Sites in Cincinnati, Columbus +1 more location

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 4 - 39

Code: NCT05278208·Phase 1, Phase 2·Recruiting·Listed Mar 2022

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Study of Letrozole in Recurrent Gliomas

for Brain Tumor

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT03122197·EARLY_Phase 1·Recruiting·Listed Apr 2017

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NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial

for Neuroblastoma

Drug: Irinotecan

Sites in Cincinnati, Columbus +11 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 1 - 31

Code: NCT06450041·Phase 2·Recruiting·Listed Jun 2024

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Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

for Multiple Myeloma

Drug: Teclistamab

Sites in Cincinnati, Columbus +39 more locations

Sponsor: European Myeloma Network B.V.

Sex: All·Age: 18+

Code: NCT05243797·Phase 3·Recruiting·Listed Feb 2022

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Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma

for Head and Neck Cancer

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT07213934·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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Collection of Research Data and Samples From Patients Treated With Immunotherapy to Study Its Side Effects

for Hematopoietic and Lymphoid Cell Neoplasm

Sites in Cincinnati, Franklin +392 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting·Listed Jan 2020

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Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion

for High Grade Glioma

Sites in Cincinnati, Columbus +8 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 - 21·Accepts healthy volunteers

Code: NCT06333899·EARLY_Phase 1·Recruiting·Listed Mar 2024

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Outpatient Administration of Teclistamab or Talquetamab for Multiple Myeloma

for Multiple Myeloma

Drug: Talquetamab

Sites in Cincinnati +15 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 18+

Code: NCT05972135·Phase 2·Recruiting·Listed Aug 2023

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Pharmacokinetic Study of Venetoclax Tablets Crushed and Dissolved Into a Solution

for Hematologic Malignancy

Drug: Venetoclax

Sites in Cincinnati +4 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 0 - 38

Code: NCT06131801·Recruiting·Listed Nov 2023

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VITAS: Atezolizumab in Combination With Chemotherapy for Pediatric Relapsed/Refractory Solid Tumors

for Solid Tumor

Drug: Atezolizumab

Sites in Cincinnati +6 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 6 Months - 30

Code: NCT04796012·Phase 1, Phase 2·Recruiting·Listed Mar 2021

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Registry Study for Radiation Therapy Outcomes

for Neoplasms

Sites in Cincinnati +28 more locations

Sponsor: Proton Collaborative Group

Sex: All·Age: All ages

Code: NCT01255748·Recruiting·Listed Dec 2010

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Comparing Cooling and/or Compression Approaches of Limbs for Prevention of Chemotherapy-Induced Peripheral Neuropathy

for Malignant Solid Neoplasm

Sites in Cincinnati +32 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05642611·Phase 3·Recruiting·Listed Dec 2022

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Cincinnati +8 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

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Novel, One Stop, Affordable, Point of Care and AI Supported System of Screening, Triage and Treatment Selection for Cervical Cancer in LMICs

for Cervical Cancer

1 location in Cincinnati

Sponsor: International Agency for Research on Cancer

Sex: Female·Age: 25 - 49

Code: NCT06042543·Recruiting·Listed Sep 2023

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

Sites in Cincinnati +131 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting·Listed Apr 2023

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Sacituzumab Govitecan +/- Pembrolizumab in Metastatic TNBC

for Breast Cancer

Sites in Cincinnati, Columbus +13 more locations

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT04468061·Phase 2·Recruiting·Listed Jul 2020

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

Sites in Cincinnati, West Chester +338 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting·Listed Aug 2020

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A Study of Selinexor in People With Wilms Tumors and Other Solid Tumors

for Wilms Tumor

Drug: Selinexor

Sites in Cincinnati +15 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 12 Months+

Code: NCT05985161·Phase 2·Recruiting·Listed Aug 2023

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Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

for High Grade Glioma

Drug: Ribociclib

Sites in Cincinnati, Columbus +9 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT05843253·Phase 2·Recruiting·Listed May 2023

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Promoting Immunotherapy Efficacy With Low-Dose Liver RT

for Low-Dose Liver Radiation (LD-LRT)

1 location in Cincinnati

Sponsor: Jordan Kharofa

Sex: All·Age: 18+

Code: NCT07225036·Recruiting·Listed Nov 2025

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Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors

for Cancer

1 location in Cincinnati

Sponsor: University of Cincinnati

Sex: All·Age: 18+

Code: NCT06416007·Phase 2·Recruiting·Listed May 2024

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Neuroblastoma Biology Study

for Neuroblastoma

Sites in Cincinnati, Columbus +12 more locations

Sponsor: New Approaches to Neuroblastoma Therapy Consortium

Sex: All·Age: 31 Days - 99

Code: NCT01587300·Recruiting·Listed Apr 2012

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A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion

for High Grade Glioma

Sites in Cincinnati, Columbus +7 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: Up to 21

Code: NCT04655404·EARLY_Phase 1·Recruiting·Listed Dec 2020

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Cytokine-Induced Memory-Like Natural Killer Cells (CIML-NK) for Relapsed & Refractory Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2+

Code: NCT05580601·Phase 1, Phase 2·Recruiting·Listed Oct 2022

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Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

for Hepatocellular Carcinoma, Childhood

Sites in Cincinnati +4 more locations

Sponsor: Allison O'Neill, MD

Sex: All·Age: 0 - 30

Code: NCT04134559·Phase 2·Recruiting·Listed Oct 2019

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Venetoclax Combined With Vyxeos (CPX-351) for Participants With Relapsed or Refractory Acute Leukemia

for Leukemia

Drug: Venetoclax

1 location in Cincinnati

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 1 - 39

Code: NCT03826992·Phase 1·Recruiting·Listed Feb 2019

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Conditions in Oncology (Cincinnati, OH)

Solid tumor· 24 Non-small cell lung cancer (NSCLC)· 23 Breast cancer· 14 Acute myeloid leukemia (AML)· 13 Multiple myeloma· 11 Colorectal cancer· 10 Ovarian cancer· 10 Prostate cancer· 9 Non-Hodgkin lymphoma· 9 Endometrial cancer· 8 Chronic lymphocytic leukemia (CLL)· 8 Melanoma· 8 Cancer (any)· 8 Glioma· 7 Diffuse large B-cell lymphoma (DLBCL)· 7 Head and neck cancer· 7 Neuroblastoma· 7 Pancreatic cancer· 6 Leukemia (other)· 6 Hematologic malignancy· 6 Metastatic prostate cancer· 5 Glioblastoma· 5 Small lymphocytic lymphoma· 5 Myelofibrosis· 4 Osteosarcoma· 4 Triple-negative breast cancer· 3 Small cell lung cancer· 3 Gastric cancer· 3 Esophageal cancer· 3 Bladder cancer· 3 Fallopian tube cancer· 3 Brain cancer· 3 Myeloproliferative neoplasm· 3 Hodgkin lymphoma· 3 Follicular lymphoma· 3 Sarcoma· 3 Lung cancer· 2 Metastatic colorectal cancer· 2 Gastroesophageal junction cancer· 2 Biliary tract cancer· 2 Gastrointestinal cancer· 2 Kidney cancer· 2 Cervical cancer· 2 Acute lymphoblastic leukemia· 2 Myelodysplastic syndromes (MDS)· 2 Mantle cell lymphoma· 2 Marginal zone lymphoma· 2 Ewing sarcoma· 2 Metastatic breast cancer· 1 Rectal cancer· 1 Liver cancer· 1 Burkitt lymphoma· 1 Rhabdomyosarcoma· 1 Neuroendocrine tumors· 1