Clinical Trials at University Hospitals Cleveland Medical Center

As of July 2026, 144 paid clinical trials are recruiting at University Hospitals Cleveland Medical Center, located at 11100 EUCLID AVE, CLEVELAND, OH 44106-1716, phone (216) 844-8447 in Cleveland, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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149 clinical trials at University Hospitals Cleveland Medical Center

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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

for Pneumonia

Sites in Cleveland, Beachwood +37 more locations

Sponsor: Pfizer

Sex: All·Age: 65+

Code: NCT05452941·Recruiting·Listed Jul 2022

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

Sites in Cleveland +32 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS (Master Record)

for Acute Respiratory Distress Syndrome (ARDS)

Sites in Cleveland, Toledo +37 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06703073·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort C: Bevacizumab

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Bevacizumab

Sites in Cleveland, Toledo +37 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701656·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort B: Paridiprubart

for Acute Respiratory Distress Syndrome (ARDS)

Drug: Cohort B: paridiprubart

Sites in Cleveland, Toledo +37 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701669·Phase 2·Recruiting·Listed Nov 2024

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JUST BREATHE, Breathing Life Into Innovative Therapies for ARDS- Cohort A: Vilobelimab

for Acute Respiratory Distress Syndrome (ARDS)

Sites in Cleveland, Toledo +37 more locations

Sponsor: PPD Development, LP

Sex: All·Age: 18+

Code: NCT06701682·Phase 2·Recruiting·Listed Nov 2024

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

Sites in Cleveland, Dublin +68 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

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Prevail Global Study

for Coronary Artery Disease

Sites in Cleveland, Columbus +49 more locations

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting·Listed Aug 2024

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SELUTION4BTK Trial

for Peripheral Arterial Disease

Sites in Cleveland +24 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05055297·Recruiting·Listed Sep 2021

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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

Sites in Cleveland +7 more locations

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting·Listed Apr 2022

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A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

for Carcinoma, Non-Small-Cell Lung

Sites in Cleveland +24 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT05208762·Phase 1·Recruiting·Listed Jan 2022

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A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

for Myelodysplastic Syndrome

Sites in Cleveland, Columbus +40 more locations

Sponsor: Seagen, a wholly owned subsidiary of Pfizer

Sex: All·Age: 18+

Code: NCT04227847·Phase 1·Recruiting·Listed Jan 2020

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Cleveland, Columbus +42 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023

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Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

for Arterial Disease of Legs

Sites in Cleveland, Cincinnati +27 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 21+

Code: NCT06182397·Recruiting·Listed Dec 2023

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Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

for Neurotrophic Keratopathy

Sites in Cleveland +23 more locations

Sponsor: ReGenTree, LLC

Sex: All·Age: 18+

Code: NCT05555589·Phase 3·Recruiting·Listed Sep 2022

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A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

for Parkinson Disease

Sites in Cleveland, Canton +25 more locations

Sponsor: Impax Laboratories, LLC

Sex: All·Age: 18+

Code: NCT06765668·Phase 4·Recruiting·Listed Jan 2025

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Symbiotic-Lung-04: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Extensive-Stage Small Cell Lung Cancer

for Small Cell Lung Cancer (SCLC)

Drug: PF-08634404

Sites in Cleveland +23 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07226999·Phase 2, Phase 3·Recruiting·Listed Nov 2025

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A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

for Advanced or Metastatic Solid Tumors

Sites in Cleveland +14 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT07205718·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

for Small Cell Lung Cancer

Drug: Atezolizumab

Sites in Cleveland +9 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07155174·Phase 2·Recruiting·Listed Sep 2025

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Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

for Epilepsy

Sites in Cleveland +15 more locations

Sponsor: Epiminder America, Inc.

Sex: All·Age: 18 - 75

Code: NCT07110454·Recruiting·Listed Aug 2025

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

Sites in Cleveland +10 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025

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Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen

for Carcinoid Syndrome

Sites in Cleveland +16 more locations

Sponsor: Crinetics Pharmaceuticals Inc.

Sex: All·Age: 18+

Code: NCT07087054·Phase 3·Recruiting·Listed Jul 2025

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

for Metastatic Solid Tumor

Drug: LY4052031

Sites in Cleveland +16 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06465069·Phase 1·Recruiting·Listed Jun 2024

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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

Sites in Cleveland +17 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting·Listed Oct 2024

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A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Adult Participants With Previously Untreated Follicular Lymphoma

for Follicular Lymphoma (FL)

Drug: Odronextamab

Sites in Cleveland +13 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091254·Phase 3·Recruiting·Listed Oct 2023

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A Study to Learn More About the Effects and Safety of Felzartamab Infusions in Adults With Primary Membranous Nephropathy (PMN)

for Primary Membranous Nephropathy

Sites in Cleveland +14 more locations

Sponsor: Biogen

Sex: All·Age: 18 - 80

Code: NCT06962800·Phase 3·Recruiting·Listed May 2025

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A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

for Diffuse Large B-cell Lymphoma (DLBCL)

Drug: Odronextamab

Sites in Cleveland +16 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06091865·Phase 3·Recruiting·Listed Oct 2023

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Onyx™ Liquid Embolic IDE Clinical Study

for Peripheral Arterial Hemorrhage

Sites in Cleveland, Columbus +16 more locations

Sponsor: Medtronic Endovascular

Sex: All·Age: 22+

Code: NCT06742801·Recruiting·Listed Dec 2024

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SLV-154 Treatment of Metastatic Solid Tumors

for Squamous Cell Cancer of Head and Neck (SCCHN)

Sites in Cleveland +9 more locations

Sponsor: Solve Therapeutics

Sex: All·Age: 18+

Code: NCT06771219·Phase 1·Recruiting·Listed Jan 2025

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The Ailliance Post-Market Clinical Study

for Spinal Deformity

Sites in Cleveland, Columbus +21 more locations

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting·Listed May 2023

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TTVR Early Feasibility Study

for Tricuspid Regurgitation

Sites in Cleveland, Columbus +17 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT04433065·Recruiting·Listed Jun 2020

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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

for Ulcerative Colitis

Sites in Cleveland +19 more locations

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT05287126·Phase 2·Recruiting·Listed Mar 2022

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A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

for Metastatic Castration-Resistant Prostate Cancer

Sites in Cleveland +19 more locations

Sponsor: Kyntra Bio

Sex: Male·Age: 18+

Code: NCT06842498·Phase 2·Recruiting·Listed Feb 2025

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A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

for Crohn's Disease (CD)

Sites in Cleveland +14 more locations

Sponsor: Takeda

Sex: All·Age: 2 - 17

Code: NCT04779320·Phase 3·Recruiting·Listed Mar 2021

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Clinical Trial of N-803 Plus Tislelizumab or Prior Failed Immune Checkpoint Inhibitor and Docetaxel Versus Docetaxel Monotherapy in Participants With Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Acquired Resistance to Immune Checkpoint In

for NSCLC Stage IV

Sites in Cleveland, Cincinnati +17 more locations

Sponsor: ImmunityBio, Inc.

Sex: All·Age: 18 - 90

Code: NCT06745908·Phase 3·Recruiting·Listed Dec 2024

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A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia

for Primary Immune Thrombocytopenia (ITP)

Sites in Cleveland, Columbus +15 more locations

Sponsor: argenx

Sex: All·Age: 18+

Code: NCT06544499·Phase 3·Recruiting·Listed Aug 2024

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Efficacy and Safety of Subcutaneous Dupilumab in Participants With Asthma/Asthmatic Wheeze Aged 2 to <6 Years (LIBERTY ASTHMA TREKIDS)

for Wheezing

Drug: Dupilumab

Sites in Cleveland, Cincinnati +12 more locations

Sponsor: Sanofi

Sex: All·Age: 2 - 5

Code: NCT06191315·Phase 3·Recruiting·Listed Jan 2024

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Study to Learn About the Safety of Fazirsiran and if it Can Help People With Alpha-1 Antitrypsin Liver Disease With Mild Liver Scarring (Fibrosis)

for Alpha1-Antitrypsin Deficiency

Sites in Cleveland +19 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06165341·Phase 3·Recruiting·Listed Dec 2023

Apply to this trial

A Study of HC-7366 in Combination With Belzutifan (WELIREG™) in Patients With Renal Cell Carcinoma

for Renal Cell Carcinoma

Sites in Cleveland +19 more locations

Sponsor: HiberCell, Inc.

Sex: All·Age: 18+

Code: NCT06234605·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

CERAMENT™| Bone Void Filler Device Registry

for Orthopedic Disorder

Sites in Cleveland +10 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT04244942·Recruiting·Listed Jan 2020

Apply to this trial