As of September 2026, 1,261 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Cleveland offers studies at sites including Cleveland Clinic for conditions such as Heart Failure, Breast Cancer, Advanced Solid Tumor, Cardiovascular Diseases. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Researchers run research studies in Cleveland, OH at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Cleveland Clinic | Heart Failure, Cardiovascular Diseases, Colorectal Cancer | 363 |
| University Hospitals Cleveland Medical Center | ARDS, ARDS (Acute Respiratory Distress Syndrome), Acute Respiratory Distress Syndrome | 157 |
| Cleveland Clinic Foundation | Heart Failure, COPD, Stroke | 141 |
| Case Western Reserve University | Acute Myeloid Leukemia, Stage IV Lung Cancer AJCC v8, Dementia | 76 |
| MetroHealth Medical Center | Spinal Cord Injuries, Spinal Cord Injury Cervical, Stage IVB Prostate Cancer AJCC v8 | 35 |
| The Cleveland Clinic Foundation | Heart Diseases, Aortic Valve Insufficiency, Cardiovascular Diseases | 27 |
| Rainbow Babies and Childrens Hospital | Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia, Down Syndrome | 26 |
| Louis Stokes VA Medical Center, Cleveland, OH | Spinal Cord Injury, Diabetes, Parkinson's Disease | 24 |
| Cleveland Clinic Main Campus | Breast Cancer, Abdominal Wall Hernia, Blood Pressure | 18 |
| The Cleveland Clinic | Depression / Major Depressive Disorder, Hopelessness, Suicidal Ideation | 17 |
| Cleveland Clinic Cancer Center/Fairview Hospital | Ovarian Carcinoma, Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer | 13 |
| University Hospitals | B Cell Lymphoma, Bladder Pain Syndrome, CLL | 12 |
| UH Cleveland Medical Center | Breast Cancer, Acute Decompensated Heart Failure, Atrial Fibrillation | 11 |
| University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center | Acute Lymphocytic Leukemia, Bile Duct Cancer, Brain Metastases | 11 |
| University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center | Pancreatic Cancer, Adenocarcinoma of the Colon, Adenocarcinoma of the Rectum | 10 |
| University Hospitals of Cleveland | Advanced Solid Tumors, Aortic Aneurysm, Aortic Dissection | 9 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation Taussig Cancer Institute | Amyloid Light-chain Amyloidosis, B-cell Non Hodgkin Lymphoma, Basal Cell Carcinoma | 8 |
| Cleveland Clinic Taussig Cancer Center | Glioma, Advanced Solid Tumor, Barrett Esophagus | 8 |
| The MetroHealth System | AV Block, COVID-19, Coronavirus Infections | 8 |
| University Hospitals Cleveland | 1st Line NSCLC, Abdominal Aortic Aneurysm, Advanced Solid Tumor | 8 |
| Cleveland Clinic Fairview Hospital | HPV Infection, Pre-Cancerous Dysplasia, Bleeding | 7 |
| Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center | Acute Myeloid Leukemia, Cyst of Pancreas, Cytokine Release Syndrome | 7 |
| Louis Stokes Cleveland VA Medical Center | Multiple Sclerosis, Stroke, Adenocarcinoma of the Colon | 7 |
| MetroHealth | Acute Kidney Injury, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8 | 7 |
| Case Comprehensive Cancer Center, Cleveland Clinic Foundation | Head and Neck Cancer, Oral Cancer, Cancer | 6 |
Recruiting trials in Cleveland grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
There are approximately 1,261 recruiting clinical trials in Cleveland, Ohio listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Most recruiting trials in Cleveland compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
The most common conditions under active study in Cleveland include Heart Failure (29), Breast Cancer (19), Advanced Solid Tumor (18), Cardiovascular Diseases (17), among many others. Browse the list above to explore every recruiting trial.
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Cleveland on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Recruiting research sites in Cleveland include Cleveland Clinic, University Hospitals Cleveland Medical Center, Cleveland Clinic Foundation, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
The largest active categories in Cleveland are Cancer & tumors (376), Cardiovascular (105), Neurology & pain (85). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.