Clinical Trials at University Hospitals Cleveland Medical Center

As of July 2026, 144 paid clinical trials are recruiting at University Hospitals Cleveland Medical Center, located at 11100 EUCLID AVE, CLEVELAND, OH 44106-1716, phone (216) 844-8447 in Cleveland, Ohio. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

View the full facility profile →

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 19, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

149 clinical trials at University Hospitals Cleveland Medical Center

·Clear filters·↓ Download CSV

CERAMENT™| Bone Void Filler Device Registry

for Orthopedic Disorder

Sites in Cleveland +10 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT04244942·Recruiting·Listed Jan 2020

Apply to this trial

AltaValve Pivotal Trial

for Mitral Regurgitation

Sites in Cleveland +19 more locations

Sponsor: 4C Medical Technologies, Inc.

Sex: All·Age: 18+

Code: NCT06465745·Recruiting·Listed Jun 2024

Apply to this trial

Study of AVZO-021 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Cleveland +10 more locations

Sponsor: Avenzo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05867251·Phase 1, Phase 2·Recruiting·Listed May 2023

Apply to this trial

PANTHER Study of Terumo Aortic Knitted and Woven Grafts, and Cardiovascular Patches

for Aneurysm

Sites in Cleveland, Columbus +8 more locations

Sponsor: Vascutek Ltd.

Sex: All·Age: 18+

Code: NCT04545502·Recruiting·Listed Sep 2020

Apply to this trial

A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)

for T Cell Malignancies

Sites in Cleveland +5 more locations

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07465835·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer

for Relapsed/Refractory Small Cell Lung Cancer

Sites in Cleveland +4 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07325136·Phase 1, Phase 2·Recruiting·Listed Jan 2026

Apply to this trial

A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

for Prostatic Neoplasms

Drug: Pasritamig

Sites in Cleveland +2 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07319871·Phase 1·Recruiting·Listed Jan 2026

Apply to this trial

Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

for Large Cell Neuroendocrine Carcinoma

Sites in Cleveland +4 more locations

Sponsor: Molecular Partners AG

Sex: All·Age: 18+

Code: NCT07278479·Phase 1, Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

for Prostatic Neoplasms

Sites in Cleveland +3 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07082920·Phase 1·Recruiting·Listed Jul 2025

Apply to this trial

L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

for Acute Myeloid Leukaemia (AML)

Sites in Cleveland +5 more locations

Sponsor: Moleculin Biotech, Inc.

Sex: All·Age: 18 - 80

Code: NCT06788756·Phase 2, Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

for Solid Tumors

1 location in Cleveland

Sponsor: Spectrum Pharmaceuticals, Inc

Sex: All·Age: 1 Month - 17

Code: NCT04570423·Phase 2·Recruiting·Listed Sep 2020

Apply to this trial

A Study to Evaluate Preventive Treatments for GPRC5D-related Oral Events

for Multiple Myeloma

Sites in Cleveland +8 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06500884·Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Substudy 01A: Safety and Efficacy of Opevesostat (MK-5684)-Based Treatment Combinations or Opevesostat Alone in Participants With Metastatic Castration-resistant Prostate Cancer (mCRPC) (MK-5684-01A)

for Prostatic Neoplasms, Castration-Resistant

Sites in Cleveland +4 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06353386·Phase 1, Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

for Glomerulonephritis, IGA

Drug: Iptacopan

Sites in Cleveland, Columbus +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 99

Code: NCT06797518·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

PrProfile: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ION717

for Prion Disease

Sites in Cleveland +2 more locations

Sponsor: Ionis Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06153966·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

SLV-324 Treatment of Metastatic Solid Tumors

for Metastatic Solid Tumors

Sites in Cleveland +6 more locations

Sponsor: Solve Therapeutics

Sex: All·Age: 18+

Code: NCT07108114·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

A Study to Evaluate the Impact of Upadacitinib on Spondyloarthritis Outcomes in Patients With Active Psoriatic Arthritis

for Psoriatic Arthritis

Drug: Upadacitinib

Sites in Cleveland +2 more locations

Sponsor: CARE ARTHRITIS LTD.

Sex: All·Age: 18+

Code: NCT06454188·Phase 4·Recruiting·Listed Jun 2024

Apply to this trial

Pelvic Health Electrically Evoked Recording (PEER) 2 Study

for Overactive Bladder

Sites in Cleveland, Hilliard +3 more locations

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT05200923·Recruiting·Listed Jan 2022

Apply to this trial

Study of ISM6331 in Participants With Advanced/Metastatic Malignant Mesothelioma or Other Solid Tumors

for Malignant Mesothelioma

Sites in Cleveland +5 more locations

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06566079·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

Auryon Atherectomy System With Standard Balloon Angioplasty Versus Standard Balloon Angioplasty Alone

for Peripheral Arterial Diseases

Sites in Cleveland +8 more locations

Sponsor: Angiodynamics, Inc.

Sex: All·Age: All ages

Code: NCT06777901·Phase 4·Recruiting·Listed Jan 2025

Apply to this trial

CERAMENT G Device Registry

for Chronic Osteomyelitis

Sites in Cleveland +2 more locations

Sponsor: BONESUPPORT AB

Sex: All·Age: 18+

Code: NCT06010433·Recruiting·Listed Aug 2023

Apply to this trial

Phase 1 Study Evaluating BA3182 in Patients With Advanced Adenocarcinoma.

for Advanced Adenocarcinoma

Sites in Cleveland, Cincinnati +7 more locations

Sponsor: BioAtla, Inc.

Sex: All·Age: 18+

Code: NCT05808634·Phase 1·Recruiting·Listed Apr 2023

Apply to this trial

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

for Relapsed/Refractory B-cell Malignancies

Sites in Cleveland, Columbus +6 more locations

Sponsor: Accutar Biotechnology Inc

Sex: All·Age: 18+

Code: NCT05780034·Phase 1·Recruiting·Listed Mar 2023

Apply to this trial

The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study

for Mitral Valve Insufficiency

Sites in Cleveland +4 more locations

Sponsor: Half Moon Medical

Sex: All·Age: 21 - 95

Code: NCT04343313·Recruiting·Listed Apr 2020

Apply to this trial

ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)

for Coronary Artery Disease

Sites in Cleveland +16 more locations

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT07559903·Recruiting·Listed Apr 2026

Apply to this trial

PrP-targeting siRNA Safety & Mechanism Study

for Prion Disease

Sites in Cleveland +4 more locations

Sponsor: Broad Institute of MIT and Harvard

Sex: All·Age: 18+

Code: NCT07444580·Phase 1·Recruiting·Listed Mar 2026

Apply to this trial

Rectus Abdominis Detrusor Myoplasty for Urinary Retention

for Urinary Retention

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 75

Code: NCT07379814·Recruiting·Listed Jan 2026

Apply to this trial

Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Cleveland +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

Apply to this trial

Gender Affirming Vaginoplasty With Tubularized Augmented Peritoneal Cap (TAPCap) Utilizing Fish Skin Xenograft (Kerecis™)

for Gender Dysphoria, Adult

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Male·Age: 19 - 99

Code: NCT07286123·Recruiting·Listed Dec 2025

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Cleveland +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

Apply to this trial

Application of a Prediction Model for Directing Antibiotic Use in the Treatment of Urinary Tract Infection in an Ambulatory Setting

for Urinary Tract Infections

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18+

Code: NCT06976125·Recruiting·Listed May 2025

Apply to this trial

Innovating Physical Therapy: A Pilot Study on Band Connect's Impact on Compliance, Satisfaction, and Revenue

for Rotator Cuff Tears

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 89

Code: NCT06733480·Recruiting·Listed Dec 2024

Apply to this trial

Use of Thermal Imaging Camera to Assess Perfusion Before and After Vascular Intervention

for Peripheral Arterial Disease

Sites in Cleveland, Parma & Beachwood

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18 - 99

Code: NCT06544135·Recruiting·Listed Aug 2024

Apply to this trial

Narrow Excision Versus Wide Excision for the Treatment of Adults With Invasive Cutaneous Melanoma, ICEMAN Trial

for Clinical Stage IA Cutaneous Melanoma AJCC v8

Sites in Cleveland +4 more locations

Sponsor: OHSU Knight Cancer Institute

Sex: All·Age: 18+

Code: NCT06673095·Recruiting·Listed Nov 2024

Apply to this trial

BELIEVE Trial: Bulking vErsus sLing for Treating Stress Urinary IncontinEnce at the Time of Vaginal prolapsE Repair (BELIEVE)

for Stress Urinary Incontinence

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: Female·Age: 18+

Code: NCT06754046·Recruiting·Listed Dec 2024

Apply to this trial

Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block

for Pain

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 21 - 75

Code: NCT07174440·Recruiting·Listed Sep 2025

Apply to this trial

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

for Stage III Ovarian Cancer

Drug: Niraparib

Sites in Cleveland, Westlake +57 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05659381·Phase 3·Recruiting·Listed Dec 2022

Apply to this trial

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for Non-muscle-invasive Bladder Cancer

Sites in Cleveland +7 more locations

Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT05796375·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Using Mindfulness in an Enhanced Recovery After Surgery Protocol to Support Recovery After Colorectal Surgery

for Pain After Surgery

1 location in Cleveland

Sponsor: University Hospitals Cleveland Medical Center

Sex: All·Age: 18+

Code: NCT07026786·Recruiting·Listed Jun 2025

Apply to this trial

Obeticholic Acid for Prevention in Barrett's Esophagus

for Barrett Esophagus

Sites in Cleveland +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04939051·Phase 2·Recruiting·Listed Jun 2021

Apply to this trial