Paid Clinical Trials in Cleveland, OH

As of September 2026, 1,261 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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1,129 clinical trials

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Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1

for Focal Seizure

Sites in Cleveland +10 more locations

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 75

Code: NCT07563881·Phase 3·Recruiting·Listed May 2026

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EXACT Study: A Blinded Study in Patients With Alport Syndrome to Evaluate Exaluren Efficacy and Safety

for Alport Syndrome, X-Linked

Sites in Cleveland +7 more locations

Sponsor: Eloxx Pharmaceuticals, Inc.

Sex: All·Age: 12+

Code: NCT07523581·Phase 2·Recruiting·Listed Apr 2026

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A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma

for Metastatic Pancreatic Ductal Adenocarcinoma

Sites in Cleveland +7 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07490301·Phase 2, Phase 3·Recruiting·Listed Mar 2026

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Post Approval Effectiveness and Durability Evaluation of the Altaviva™ Tibial Device

for Urge Urinary Incontinence

Sites in Cleveland, Gahanna +11 more locations

Sponsor: MedtronicNeuro

Sex: All·Age: 18+

Code: NCT07456865·Recruiting·Listed Mar 2026

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A Study of ELA026 in Participants With Relapsed/Refractory (R/R) T/NK Cell Malignancies (TCMs)

for T Cell Malignancies

Sites in Cleveland +5 more locations

Sponsor: Electra Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT07465835·Phase 1·Recruiting·Listed Mar 2026

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Self Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD)

for Angina Pectoris

Sites in Cleveland, Cincinnati +1 more location

Sponsor: VahatiCor, Inc.

Sex: All·Age: 18+

Code: NCT07449325·Recruiting·Listed Mar 2026

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A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

for Prostatic Neoplasms

1 location in Cleveland

Sponsor: Bayer

Sex: Male·Age: 18+

Code: NCT07406282·Recruiting·Listed Feb 2026

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A Study to Assess the Safety and Tolerability of BMS-986525 Alone and in Combination Therapy in Participants With Relapsed/Refractory Small Cell Lung Cancer

for Relapsed/Refractory Small Cell Lung Cancer

Sites in Cleveland +4 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07325136·Phase 1, Phase 2·Recruiting·Listed Jan 2026

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A Study of Pasritamig (JNJ-78278343) in Combination With JNJ-86974680 for Treatment of Prostate Cancer

for Prostatic Neoplasms

Drug: Pasritamig

Sites in Cleveland +2 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07319871·Phase 1·Recruiting·Listed Jan 2026

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EncompaSSc: Evaluation of MTX-474 in Participants With Diffuse Cutaneous Systemic Sclerosis (dcSSc)

for Diffuse Cutaneous Systemic Sclerosis

Sites in Cleveland +22 more locations

Sponsor: Mediar Therapeutics

Sex: All·Age: 18+

Code: NCT07287670·Phase 2·Recruiting·Listed Dec 2025

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Ambulatory Long Length URodynamics Evaluation

for Urology

Sites in Cleveland +6 more locations

Sponsor: Bright Uro

Sex: All·Age: 22+

Code: NCT07425015·Recruiting·Listed Feb 2026

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KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04)

for Bladder Cancer

Sites in Cleveland +3 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07232602·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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A Randomized Placebo-procedure Controlled Trial of the Enhancor System (PULmonary Artery Denervation) to Evaluate Safety and Efficacy in Patients With Combined Pre- and Post-capillary Pulmonary Hypertension Associated With Left Heart Disease

for Pulmonary Hypertension

Sites in Cleveland +5 more locations

Sponsor: Pulnovo Medical, Inc.

Sex: All·Age: 18 - 85

Code: NCT07214376·Recruiting·Listed Oct 2025

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An Open-label Dose Escalation and Expansion, Followed by a Phase II Study of Tulmimetostat (DZR123) and JSB462 (Luxdegalutamide) in Patients With Progressive Metastatic Castrate Resistant Prostate Cancer (mCRPC) (TulmiSTAR-01)

for Progressive Metastatic Castrate Resistant Prostate Cancer

Drug: Tulmimetostat

Sites in Cleveland +7 more locations

Sponsor: Novartis Pharmaceuticals

Sex: Male·Age: 18+

Code: NCT07206056·Phase 1, Phase 2·Recruiting·Listed Oct 2025

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A Phase Ⅰ/Ⅱa Study of HMPL-A251 in Participants With Advanced or Metastatic HER2-expressing Solid Tumors

for Solid Tumors, Adult

Sites in Cleveland +7 more locations

Sponsor: Hutchmed

Sex: All·Age: 18+

Code: NCT07228247·Phase 1, Phase 2·Recruiting·Listed Nov 2025

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L19IL2 or L19TNF or L19IL2/TNF in Patients With Basal Cell Carcinoma (BCC)

for Locally Advanced Basal Cell Carcinoma

Sites in Cleveland, Columbus +4 more locations

Sponsor: Philogen S.p.A.

Sex: All·Age: 18+

Code: NCT07227350·Phase 2·Recruiting·Listed Nov 2025

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Glycogen Storage Disease Type Ia (GSDIa) Disease Monitoring Program

for Glycogen Storage Disease Type Ia

Sites in Cleveland +8 more locations

Sponsor: Ultragenyx Pharmaceutical Inc

Sex: All·Age: 2+

Code: NCT06636383·Recruiting·Listed Oct 2024

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Study of [212Pb]Pb-DOTAM-MAM279 ([212Pb]Pb-MP0712) in Patients With Small Cell Lung Cancer and Other DLL3 Expressing Solid Tumors

for Large Cell Neuroendocrine Carcinoma

Sites in Cleveland +4 more locations

Sponsor: Molecular Partners AG

Sex: All·Age: 18+

Code: NCT07278479·Phase 1, Phase 2·Recruiting·Listed Dec 2025

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A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

for Catecholaminergic Polymorphic Ventricular Tachycardia

Sites in Cleveland +3 more locations

Sponsor: Solid Biosciences Inc.

Sex: All·Age: 7+

Code: NCT07148089·Phase 1·Recruiting·Listed Aug 2025

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Study of ISM6331 in Participants With Advanced/Metastatic Mesothelioma or Other Advanced Solid Tumors

for Malignant Mesothelioma

Sites in Cleveland +5 more locations

Sponsor: InSilico Medicine Hong Kong Limited

Sex: All·Age: 18+

Code: NCT06566079·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

for Prostatic Neoplasms

Sites in Cleveland +3 more locations

Sponsor: Janssen Research & Development, LLC

Sex: Male·Age: 18+

Code: NCT07082920·Phase 1·Recruiting·Listed Jul 2025

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Phase 1 Study of Intratumoral Administration of VAX014 With Expansion in Combination With a Checkpoint Inhibitor in Subjects With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Cleveland +7 more locations

Sponsor: Vaxiion Therapeutics

Sex: All·Age: 18+

Code: NCT05901285·Phase 1·Recruiting·Listed Jun 2023

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Actinium Therapy for Late-stage Aggressive Sarcomas

for Advanced Soft Tissue Sarcoma

Sites in Cleveland +4 more locations

Sponsor: Ratio Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07156565·Phase 1·Recruiting·Listed Sep 2025

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A Study to Evaluate Efficacy and Safety of Ciltacabtagene Autoleucel

for Multiple Myeloma

Sites in Cleveland +1 more location

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18 - 80

Code: NCT07149857·Phase 2·Recruiting·Listed Sep 2025

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A Clinical Trial to Test if an Investigational Combination Therapy With BNT326 and BNT327 is Safe and Potentially Beneficial for People With Advanced Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Sites in Cleveland +10 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT07111520·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability up to 6 Years of Intravenous (i.v.) Secukinumab in Pediatric Participants With Juvenile Psoriatic Arthritis (JPsA).

for Juvenile Psoriatic Arthritis

Drug: Secukinumab

Sites in Cleveland, Cincinnati +9 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 2 - 17

Code: NCT06751238·Phase 1·Recruiting·Listed Dec 2024

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Safety and Preliminary Efficacy of SA53-OS in Patients With Locally Advanced or Metastatic Solid Tumors

for Solid Tumor

Sites in Cleveland & Canton

Sponsor: Lamassu Bio Inc

Sex: All·Age: 18+

Code: NCT06578624·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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SW-682 in Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Cleveland +7 more locations

Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06251310·Phase 1·Recruiting·Listed Feb 2024

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A Study to Evaluate the Safety and Pharmacokinetics of Eflapegrastim in Pediatric Participants With Solid Tumors or Lymphomas and Treated With Myelosuppressive Chemotherapy

for Solid Tumors

1 location in Cleveland

Sponsor: Spectrum Pharmaceuticals, Inc

Sex: All·Age: 1 Month - 17

Code: NCT04570423·Phase 2·Recruiting·Listed Sep 2020

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L-Annamycin for Injection in Combination With Cytarabine Injection as Second Line Therapy for Remission Induction in Adult Subjects With Refractory/Relapsed AML

for Acute Myeloid Leukaemia (AML)

Sites in Cleveland +7 more locations

Sponsor: Moleculin Biotech, Inc.

Sex: All·Age: 18 - 80

Code: NCT06788756·Phase 2, Phase 3·Recruiting·Listed Jan 2025

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Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

for Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Sites in Cleveland +7 more locations

Sponsor: Amgen

Sex: Male·Age: 18+

Code: NCT07140900·Phase 1·Recruiting·Listed Aug 2025

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Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

for Ventricular Tachycardia (VT)

Sites in Cleveland +5 more locations

Sponsor: Medtronic Cardiac Ablation Solutions

Sex: All·Age: 18 - 85

Code: NCT06703489·Recruiting·Listed Nov 2024

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The WiSE®-UP Study (The WiSE System Utilization & Performance Study)

for Heart Failure

Sites in Cleveland +11 more locations

Sponsor: EBR Systems, Inc.

Sex: All·Age: 22+

Code: NCT07098858·Recruiting·Listed Aug 2025

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Visugromab in Cachexia International Trial

for Cancer-associated Cachexia

Sites in Cleveland, Mayfield Heights +8 more locations

Sponsor: CatalYm GmbH

Sex: All·Age: 18+

Code: NCT07112196·Phase 2, Phase 3·Recruiting·Listed Aug 2025

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A Study of REC-1245 in Participants With Unresectable, Locally Advanced, or Metastatic Cancer

for Unresectable

Sites in Cleveland +3 more locations

Sponsor: Recursion Pharmaceuticals Inc.

Sex: All·Age: 12+

Code: NCT06678659·Phase 1, Phase 2·Recruiting·Listed Nov 2024

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Z1 Hip System: Post-Market Clinical Follow Up Study

for Hip Osteoarthritis

Sites in Cleveland +3 more locations

Sponsor: Zimmer Biomet

Sex: All·Age: 18+

Code: NCT07104279·Recruiting·Listed Aug 2025

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Investigational Trial to Evaluate XC001 Delivered Via an Cardiac Catheter in Subjects With Chronic Angina.

for Refractory Angina

Sites in Cleveland, Columbus +12 more locations

Sponsor: XyloCor Therapeutics, Inc.

Sex: All·Age: 18 - 85

Code: NCT07048808·Phase 2·Recruiting·Listed Jul 2025

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STimulation to Activate RespIration

for ARDS (Moderate or Severe)

Sites in Cleveland +5 more locations

Sponsor: Lungpacer Medical Inc.

Sex: All·Age: 18+

Code: NCT06832306·Recruiting·Listed Feb 2025

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Endo-SPONGE for Treatment of Anastomotic or Hartmann's Stump Leakages in Lower Pelvic Area

for Anastomotic Leaks

Sites in Cleveland +9 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07035431·Recruiting·Listed Jun 2025

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Study of Olverembatinib (HQP1351) in Patients With CML-CP

for Chronic Myeloid Leukemia

Sites in Cleveland, Mayfield Heights +48 more locations

Sponsor: Ascentage Pharma Group Inc.

Sex: All·Age: 18+

Code: NCT06423911·Phase 3·Recruiting·Listed May 2024

Apply to this trial