Paid Clinical Trials in Cleveland, OH

As of September 2026, 1,261 paid clinical trials are recruiting in Cleveland, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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1,129 clinical trials

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Tracking Results of Ablations to Combat AF Registry Generation 2

for Atrial Fibrillation

Sites in Cleveland +25 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT05111015·Recruiting·Listed Nov 2021

Apply to this trial

PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III

for Heart Failure NYHA Class II

Sites in Cleveland, Cincinnati +43 more locations

Sponsor: Endotronix, Inc.

Sex: All·Age: 18+

Code: NCT05934487·Recruiting·Listed Jul 2023

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

Sites in Cleveland, Columbus +51 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting·Listed May 2025

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Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for Metastatic Breast Cancer

Sites in Cleveland, Columbus +29 more locations

Sponsor: LeonaBio

Sex: All·Age: 18+

Code: NCT05696626·Phase 3·Recruiting·Listed Jan 2023

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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Cleveland, Columbus +69 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

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A Study to Test How Effective Belumosudil Tablets Are for Treating Adult Participants With Chronic Lung Allograft Dysfunction

for Lung Transplant Rejection

Sites in Cleveland, Columbus +30 more locations

Sponsor: Sanofi

Sex: All·Age: 18+

Code: NCT06082037·Phase 3·Recruiting·Listed Oct 2023

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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

for Pneumonia

Sites in Cleveland, Beachwood +37 more locations

Sponsor: Pfizer

Sex: All·Age: 65+

Code: NCT05452941·Recruiting·Listed Jul 2022

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

Sites in Cleveland, Columbus +31 more locations

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Idiopathic Hypersomnia

for Idiopathic Hypersomnia

Drug: ALKS 2680

Sites in Cleveland, Canton +32 more locations

Sponsor: Alkermes, Inc.

Sex: All·Age: 18 - 70

Code: NCT06843590·Phase 2·Recruiting·Listed Feb 2025

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Study to Check the Safety of Fazirsiran and Learn if Fazirsiran Can Help People With Liver Disease and Scarring (Fibrosis) Due to an Abnormal Version of Alpha-1 Antitrypsin Protein

for Alpha1-Antitrypsin Deficiency

Sites in Cleveland +32 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT05677971·Phase 3·Recruiting·Listed Jan 2023

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The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

for Aortoiliac Occlusive Disease

Sites in Cleveland, Ashland +21 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT05811364·Recruiting·Listed Apr 2023

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The PREDICT Registry:

for DCIS

Sites in Cleveland, Akron +28 more locations

Sponsor: PreludeDx

Sex: Female·Age: 30 - 85

Code: NCT03448926·Recruiting·Listed Feb 2018

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A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

for Graft-versus-host Disease (GVHD)

Drug: Ruxolitinib

Sites in Cleveland, Columbus +28 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06615050·Phase 3·Recruiting·Listed Sep 2024

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

Sites in Cleveland, Dublin +68 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

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Prevail Global Study

for Coronary Artery Disease

Sites in Cleveland, Columbus +49 more locations

Sponsor: Medtronic Vascular

Sex: All·Age: 18+

Code: NCT06535854·Recruiting·Listed Aug 2024

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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

Sites in Cleveland +30 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06428019·Phase 3·Recruiting·Listed May 2024

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SELUTION4BTK Trial

for Peripheral Arterial Disease

Sites in Cleveland +24 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05055297·Recruiting·Listed Sep 2021

Apply to this trial

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR

for Functional Mitral Regurgitation

Sites in Cleveland, Columbus +49 more locations

Sponsor: Cardiac Dimensions, Inc.

Sex: All·Age: 18+

Code: NCT03142152·Recruiting·Listed May 2017

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MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

Sites in Cleveland, Columbus +35 more locations

Sponsor: Intellia Therapeutics

Sex: All·Age: 18 - 90

Code: NCT06128629·Phase 3·Recruiting·Listed Nov 2023

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MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

for Multiple Myeloma

Drug: Elranatamab

Sites in Cleveland, Cincinnati +91 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06152575·Phase 3·Recruiting·Listed Nov 2023

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PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

for Critical Limb Ischemia

Sites in Cleveland +7 more locations

Sponsor: LimFlow, Inc.

Sex: All·Age: 18 - 95

Code: NCT05313165·Recruiting·Listed Apr 2022

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Neoadjuvant Darovasertib in Primary Uveal Melanoma

for Uveal Melanoma

Sites in Cleveland, Columbus +33 more locations

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT07015190·Phase 3·Recruiting·Listed Jun 2025

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A Phase Ⅲ Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer

for Gastroesophageal-junction Cancer

Sites in Cleveland +28 more locations

Sponsor: Shanghai Henlius Biotech

Sex: All·Age: 18+

Code: NCT06532006·Phase 3·Recruiting·Listed Aug 2024

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Zenith® Fenestrated+ Clinical Study

for Aortic Aneurysm, Abdominal

Sites in Cleveland +29 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT04875429·Recruiting·Listed May 2021

Apply to this trial

Registry for Stage 2 Type 1 Diabetes

for Type 1 Diabetes

Sites in Cleveland, Columbus +35 more locations

Sponsor: Sanofi

Sex: All·Age: All ages

Code: NCT06481904·Recruiting·Listed Jul 2024

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Endovascular AAA Intervention Using the GORE® EXCLUDER® Conformable AAA Endoprosthesis or Iliac Branch Endoprosthesis

for AAA - Abdominal Aortic Aneurysm

Sites in Cleveland +55 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT06218875·Recruiting·Listed Jan 2024

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A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants

for Hypothyroidism

Sites in Cleveland, Canton +128 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06345339·Phase 2, Phase 3·Recruiting·Listed Apr 2024

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A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Cleveland, Columbus +42 more locations

Sponsor: Kura Oncology, Inc.

Sex: All·Age: 18+

Code: NCT05735184·Phase 1·Recruiting·Listed Feb 2023

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A Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

for Narcolepsy Type 1

Drug: ORX750

Sites in Cleveland, Dublin +27 more locations

Sponsor: Centessa Pharmaceuticals (UK) Limited

Sex: All·Age: 18 - 65

Code: NCT06752668·Phase 2·Recruiting·Listed Dec 2024

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EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)

for Breast Cancer

Sites in Cleveland, Canton +51 more locations

Sponsor: Exact Sciences Corporation

Sex: All·Age: 18+

Code: NCT06401421·Recruiting·Listed May 2024

Apply to this trial

Caris Biorepository Research Protocol

for Cancer

Sites in Cleveland, Boardman +36 more locations

Sponsor: Caris Science, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01499394·Recruiting·Listed Dec 2011

Apply to this trial

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

Sites in Cleveland, Columbus +24 more locations

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

Sirolimus Coated BALloon Versus Standard Balloon Angioplasty in The Treatment of Below The Knee Arterial Disease

for Arterial Disease of Legs

Sites in Cleveland, Cincinnati +27 more locations

Sponsor: Concept Medical Inc.

Sex: All·Age: 21+

Code: NCT06182397·Recruiting·Listed Dec 2023

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Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

for Lupus Nephritis

Sites in Cleveland +13 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100

Code: NCT05268289·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

for Acute Decompensated Heart Failure

Sites in Cleveland, Columbus +35 more locations

Sponsor: Reprieve Cardiovascular, Inc

Sex: All·Age: 22+

Code: NCT06898515·Phase 3·Recruiting·Listed Mar 2025

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Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

Sites in Cleveland, Independence +56 more locations

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting·Listed Jun 2024

Apply to this trial

PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

Sites in Cleveland, Cincinnati +27 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting·Listed Dec 2016

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A Phase 3B Study to Evaluate Bone Mineral Density With Long-Term Use of Relugolix Combination Tablet in Women With Uterine Fibroids or Endometriosis

for Uterine Fibroids

Drug: Relugolix

Sites in Cleveland, Dublin +118 more locations

Sponsor: Sumitomo Pharma Switzerland GmbH

Sex: Female·Age: 18 - 50

Code: NCT05862272·Phase 3·Recruiting·Listed May 2023

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CA-4948-101: Open-Label, Dose Escalation and Expansion Trial of Emavusertib (CA-4948) in Relapsed or Refractory Primary Central Nervous System Lymphoma (R/R PCNSL)

for Relapsed Hematologic Malignancy

Drug: Emavusertib

Sites in Cleveland +17 more locations

Sponsor: Curis, Inc.

Sex: All·Age: 18+

Code: NCT03328078·Phase 1, Phase 2·Recruiting·Listed Nov 2017

Apply to this trial

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

Sites in Cleveland, Columbus +35 more locations

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial