Paid Clinical Trials in Columbus, OH

As of September 2026, 1,368 paid clinical trials are recruiting in Columbus, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,221 clinical trials

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Impact of Behavior Modification Interventions and Lung Cancer Screening on Smoking Cessation in People Living With HIV: A Feasibility Study

for HIV Infection

Sites in Columbus +10 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 45 - 80

Code: NCT04949464·Recruiting·Listed Jul 2021

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A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for Autoimmune Hepatitis

Sites in Columbus, Cincinnati +6 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05750498·Recruiting·Listed Mar 2023

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Testing the Addition of Abemaciclib to Olaparib for Women With Recurrent Ovarian Cancer

for Recurrent Ovarian High Grade Serous Adenocarcinoma

Sites in Columbus +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT04633239·Phase 1·Recruiting·Listed Nov 2020

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

Sites in Columbus, Gahanna +586 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting·Listed May 2021

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Testing Teclistamab (TECVAYLI) in Combination With Iberdomide for Relapsed or Refractory Multiple Myeloma

for Recurrent Multiple Myeloma

Drug: Teclistamab

Sites in Columbus +13 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06465316·Phase 1·Recruiting·Listed Jun 2024

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Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

for Metastatic Colorectal Carcinoma

Sites in Columbus, Youngstown +52 more locations

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT05863195·Phase 3·Recruiting·Listed May 2023

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Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome

for Acute Respiratory Distress Syndrome

Sites in Columbus, Cincinnati +31 more locations

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06066502·Phase 3·Recruiting·Listed Oct 2023

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Once Weekly Infant Corticosteroid Trial for DMD

for Duchenne Muscular Dystrophy

Sites in Columbus, Cincinnati +2 more locations

Sponsor: Anne M. Connolly

Sex: Male·Age: 1 Month - 30 Months

Code: NCT05412394·Phase 4·Recruiting·Listed Jun 2022

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Cord Clamping Among Neonates With Congenital Heart Disease

for Congenital Heart Disease (CHD)

Sites in Columbus +17 more locations

Sponsor: Carl Backes, MD

Sex: All·Age: 37 Weeks - 42 Weeks

Code: NCT06153459·Recruiting·Listed Dec 2023

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Implementation of TBI-RECOVER in Substance Use Treatment

for Traumatic Brain Injury

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07215221·Recruiting·Listed Oct 2025

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The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

for Ischemic Heart Disease (IHD)

Sites in Columbus, Cleveland +11 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 35 - 85

Code: NCT06854458·Recruiting·Listed Mar 2025

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Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

for Cystic Fibrosis

Sites in Columbus, Dayton +57 more locations

Sponsor: Chris Goss

Sex: All·Age: 6+

Code: NCT05548283·Phase 4·Recruiting·Listed Sep 2022

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The Baby Duchenne Study: Characterizing Developmental and Clinical Outcomes in the First Three Years in Children With Duchenne Muscular Dystrophy

for Duchenne Muscular Dystrophy (DMD)

Sites in Columbus, Cincinnati +2 more locations

Sponsor: University of Rochester

Sex: Male·Age: 0 Days - 3

Code: NCT07092540·Recruiting·Listed Jul 2025

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

Sites in Columbus, Troy +101 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting·Listed Jan 2024

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Columbus, Cleveland +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

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Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia

for Recurrent Chronic Lymphocytic Leukemia

Drug: Mirdametinib

Sites in Columbus +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07061951·Phase 2·Recruiting·Listed Jul 2025

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Columbus, Grove City +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control

for Myopia

Sites in Columbus +16 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 5 - 11

Code: NCT07095894·Phase 3·Recruiting·Listed Jul 2025

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ACT001 for the Treatment of Diffuse Intrinsic Pontine Gliomas and H3K27-altered High Grade Gliomas

for Diffuse Intrinsic Pontine Gliomas (DIPG)

Sites in Columbus, Cincinnati +10 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 12 Months - 39

Code: NCT06838676·Phase 2·Recruiting·Listed Feb 2025

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Testing the Anti-cancer Drug, Glofitamab, in Patients With Mantle Cell Lymphoma (A Type of Blood Cancer) Whose Disease Returned After CAR-T Cell Therapy

for Recurrent Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Columbus, Cleveland +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07003295·Phase 2·Recruiting·Listed Jun 2025

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Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)

for Pregnancy, High Risk

1 location in Columbus

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT07293715·Phase 4·Recruiting·Listed Dec 2025

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Studying the Health Perceptions and Social Behaviors of Graduate Students at the Ohio State University for the Development of Effective Oral Nicotine Pouch Addictive Risk Communication

for Tobacco-Related Carcinoma

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07346092·Recruiting·Listed Jan 2026

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Columbus +18 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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Letrozole in Uterine Leiomyosarcoma

for Uterine Leiomyosarcoma

Sites in Columbus, Marion +32 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT05649956·Phase 2·Recruiting·Listed Dec 2022

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SPIRIT Club Chronic Brain Injury Exercise Platform

for Chronic Brain Injury

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT07169370·Recruiting·Listed Sep 2025

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Humidity in Incubators for Tiny Infants

for Extremely Premature Infant

Sites in Columbus +8 more locations

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 Days - 1 Day

Code: NCT06399861·Recruiting·Listed May 2024

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SR & Abemaciclib With/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases

for Brain Metastases

1 location in Columbus

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT04923542·Phase 1, Phase 2·Recruiting·Listed Jun 2021

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Randomized Trial on Mobile Technology and Young Drivers' Cellphone Use

for Cell Phone Use

1 location in Columbus

Sponsor: Motao Zhu

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT05163119·Recruiting·Listed Dec 2021

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Testing for Safety and Colorectal Cancer Preventive Effects of ONC201

for Colorectal Adenomatous Polyp

Sites in Columbus, Cleveland +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05630794·Phase 1·Recruiting·Listed Nov 2022

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Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

for Acute Lymphocytic Leukemia

Sites in Columbus, Cleveland +2 more locations

Sponsor: Leland Metheny

Sex: All·Age: 16 - 75

Code: NCT03104491·Phase 1, Phase 2·Recruiting·Listed Apr 2017

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A Study of Venoarterial ECMO vs Off-Pump Bilateral Orthotopic Lung Transplantation

for Lung Transplant

Sites in Columbus +8 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT05547698·Recruiting·Listed Sep 2022

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Building Social and Structural Connections for the Prevention of Opioid Use Disorder Among Youth Experiencing Homelessness

for Opioid Use Disorder

2 locations in Columbus

Sponsor: Ohio State University

Sex: All·Age: 14 - 24

Code: NCT06311838·Recruiting·Listed Mar 2024

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Targeting Aging With a Ketone Ester for Function in Frailty

for Frail Elderly

Sites in Columbus +2 more locations

Sponsor: Buck Institute for Research on Aging

Sex: All·Age: 65+·Accepts healthy volunteers

Code: NCT06645847·Recruiting·Listed Oct 2024

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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)

for Hairy Cell Leukemia

Drug: Rituximab

Sites in Columbus +9 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT06561360·Phase 2·Recruiting·Listed Aug 2024

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Vyxeos for Re-induction Treatment of Acute Myeloid Leukemia Patients With Persistent Disease After Induction

for Blasts More Than 5 Percent of Bone Marrow Nucleated Cells

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18 - 75

Code: NCT04049539·Phase 1, Phase 2·Recruiting·Listed Aug 2019

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DECIDE: A Comparative Effectiveness Trial of Metformin Versus Insulin for the Treatment of Gestational Diabetes

for Gestational Diabetes Mellitus

Sites in Columbus, Kettering +19 more locations

Sponsor: Ohio State University

Sex: Female·Age: 18+

Code: NCT06445946·Phase 4·Recruiting·Listed Jun 2024

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Cardiothoracic Critical Care as Subspecialty and Its Core Competencies

for Consensus Development

1 location in Columbus

Sponsor: Ohio State University

Sex: All·Age: All ages

Code: NCT06370338·Recruiting·Listed Apr 2024

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Rett Syndrome Registry

for Rett Syndrome

Sites in Columbus, Cincinnati +17 more locations

Sponsor: International Rett Syndrome Foundation

Sex: All·Age: 0 - 99

Code: NCT05432349·Recruiting·Listed Jun 2022

Apply to this trial

Third Party Viral Specific T-cells (VSTs)

for Viral Infection

Sites in Columbus, Cincinnati & Akron

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 2 Days+

Code: NCT02532452·Phase 2·Recruiting·Listed Aug 2015

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Studying Off Label Insurance Coverage for Patients With Cutaneous Cancers a "Filter" Observational Study

for Clinical Stage II Cutaneous Merkel Cell Carcinoma AJCC v8

1 location in Columbus

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT07215988·Recruiting·Listed Oct 2025

Apply to this trial