Paid Clinical Trials in Columbus, OH

As of September 2026, 1,367 paid clinical trials are recruiting in Columbus, Ohio. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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1,221 clinical trials

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

Sites in Columbus +39 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting·Listed Jul 2025

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Repeat Ablation of Persistent Atrial Fibrillation, Including Mitral Isthmus Catheter Ablation, With the FARAPULSE Pulsed Field Ablation System

for Persistent Atrial Fibrillation

Sites in Columbus, Cincinnati +31 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT06735534·Recruiting·Listed Dec 2024

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

Sites in Columbus, Beavercreek +272 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting·Listed Sep 2025

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A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

for Cancer Harboring BRAF Alterations

Sites in Columbus, Maumee +27 more locations

Sponsor: Fore Biotherapeutics

Sex: All·Age: 8+

Code: NCT05503797·Phase 2·Recruiting·Listed Aug 2022

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Efficacy & Safety of Olvi-Vec and Platinum-doublet + Bevacizumab Compared to Physician's Choice of Chemotherapy and Bevacizumab in Platinum-Resistant/Refractory Ovarian Cancer (PRROC) (OnPrime, GOG-3076)

for Platinum-resistant Ovarian Cancer

Drug: Bevacizumab

Sites in Columbus, Kettering +31 more locations

Sponsor: Genelux Corporation

Sex: Female·Age: 18+

Code: NCT05281471·Phase 3·Recruiting·Listed Mar 2022

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A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer

for Neoplasms

Sites in Columbus +24 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 1 - 39

Code: NCT05999994·Phase 2·Recruiting·Listed Aug 2023

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A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

for Myelofibrosis

Sites in Columbus +29 more locations

Sponsor: Sumitomo Pharma America, Inc.

Sex: All·Age: 18+

Code: NCT04176198·Phase 1, Phase 2·Recruiting·Listed Nov 2019

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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

Sites in Columbus, Cincinnati +72 more locations

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting·Listed Jul 2023

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Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer

for Low-grade NMIBC

Sites in Columbus, Springfield +34 more locations

Sponsor: Tyra Biosciences, Inc

Sex: All·Age: 18+

Code: NCT06995677·Phase 2·Recruiting·Listed May 2025

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

Sites in Columbus, Cincinnati +44 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting·Listed Sep 2019

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Columbus +25 more locations

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting·Listed Nov 2024

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

Sites in Columbus, Cincinnati +54 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024

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Pompe Disease Registry Protocol

for Glycogen Storage Disease Type II

Sites in Columbus, Dublin +72 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00231400·Recruiting·Listed Oct 2005

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A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer

for Non-muscle Invasive Bladder Cancer With Carcinoma in Situ

Drug: Nadofaragene Firadenovec

Sites in Columbus, Cincinnati +37 more locations

Sponsor: Ferring Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06545955·Phase 3·Recruiting·Listed Aug 2024

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First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

for Breast Cancer

Sites in Columbus, Cleveland +22 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT05768139·Phase 1, Phase 2·Recruiting·Listed Mar 2023

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Columbus +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

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Fabry Disease Registry & Pregnancy Sub-registry

for Fabry Disease

Sites in Columbus, Dublin +72 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00196742·Recruiting·Listed Sep 2005

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Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

Sites in Columbus, Cincinnati +30 more locations

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting·Listed Mar 2023

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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

for Generalized Anxiety Disorder (GAD)

Sites in Columbus, Cincinnati +45 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 65

Code: NCT06846320·Phase 2·Recruiting·Listed Feb 2025

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DALY II USA/ MB-CART2019.1 for DLBCL

for Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Sites in Columbus +27 more locations

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT04792489·Phase 2·Recruiting·Listed Mar 2021

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Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

Sites in Columbus, Cincinnati +31 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting·Listed Jul 2025

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ARTIST: Aortic Regurgitation Trial Investigating Surgery Versus Trilogy™

for Aortic Regurgitation

Sites in Columbus, Cincinnati +27 more locations

Sponsor: JenaValve Technology, Inc.

Sex: All·Age: All ages

Code: NCT06608823·Recruiting·Listed Sep 2024

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TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis With Cardiomyopathy

Drug: Nucresiran

Sites in Columbus, Cleveland +40 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18 - 85

Code: NCT07052903·Phase 3·Recruiting·Listed Jul 2025

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Phase 2, Efficacy and Safety Study of ACP-204 in Lewy Body Dementia Psychosis

for Lewy Body Dementia Psychosis

Sites in Columbus, Cleveland +26 more locations

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 55 - 84

Code: NCT07029581·Phase 2·Recruiting·Listed Jun 2025

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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

for Psychosis Associated With Alzheimer's Disease

Drug: KarXT

Sites in Columbus, Shaker Heights +84 more locations

Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

Sex: All·Age: 55 - 90

Code: NCT05980949·Phase 3·Recruiting·Listed Aug 2023

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Sites in Columbus, Dayton +131 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting·Listed May 2024

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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in Columbus +22 more locations

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06701903·Phase 2·Recruiting·Listed Nov 2024

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A Study to Assess Growth in Children With Idiopathic Short Stature

for Idiopathic Short Stature

Sites in Columbus, Cincinnati +28 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 2 - 16

Code: NCT06309979·Recruiting·Listed Mar 2024

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A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

Sites in Columbus, Centerville +106 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting·Listed May 2024

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Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

for Metastatic Non Small Cell Lung Cancer

Sites in Columbus, Cincinnati +19 more locations

Sponsor: Iovance Biotherapeutics, Inc.

Sex: All·Age: 18 - 70

Code: NCT04614103·Phase 2·Recruiting·Listed Nov 2020

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A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

for Treatment Resistant Depression

Sites in Columbus, Garfield Heights +51 more locations

Sponsor: LivaNova

Sex: All·Age: 18+

Code: NCT03887715·Recruiting·Listed Mar 2019

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

Sites in Columbus, Cincinnati +92 more locations

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting·Listed Jan 2025

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PINNACLE

for Macular Edema Secondary to Inflammation

Sites in Columbus, Cleveland +51 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06996080·Phase 3·Recruiting·Listed May 2025

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Study of the Long-Term Safety and Outcomes of Treating Pulmonary Embolism With the Indigo Aspiration System

for Pulmonary Embolism

Sites in Columbus, Kettering +53 more locations

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT04798261·Recruiting·Listed Mar 2021

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A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

for Macular Edema Secondary to Inflammation

Sites in Columbus, Cleveland +51 more locations

Sponsor: Kodiak Sciences Inc

Sex: All·Age: 18+

Code: NCT06990399·Phase 3·Recruiting·Listed May 2025

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Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia

for Hypertriglyceridemia

Drug: Plozasiran

Sites in Columbus, Vandalia +6 more locations

Sponsor: Arrowhead Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06822790·Phase 3·Recruiting·Listed Feb 2025

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Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

for Parkinson's Disease

Sites in Columbus +17 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT02071134·Recruiting·Listed Feb 2014

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Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation

for Metastatic Breast Cancer

Sites in Columbus, Cleveland +29 more locations

Sponsor: LeonaBio

Sex: All·Age: 18+

Code: NCT05696626·Phase 3·Recruiting·Listed Jan 2023

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A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in Columbus, Cincinnati +30 more locations

Sponsor: Dianthus Therapeutics

Sex: All·Age: 18 - 75

Code: NCT06858579·Phase 3·Recruiting·Listed Mar 2025

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Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

Sites in Columbus, Bexley +91 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06855498·Phase 3·Recruiting·Listed Mar 2025

Apply to this trial