Clinical Trials at UT Southwestern Medical Center

As of July 2026, 159 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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162 clinical trials at UT Southwestern Medical Center

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Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

for Single Ventricle Heart Disease

Sites in Dallas, Houston +35 more locations

Sponsor: Mezzion Pharma Co. Ltd

Sex: All·Age: 12 - 18

Code: NCT05918211·Phase 3·Recruiting·Listed Jun 2023

Apply to this trial

Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

Sites in Dallas +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

Apply to this trial

Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

Sites in Dallas, Tyler +13 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting·Listed Dec 2024

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Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

for Hematuria - Cause Not Known

Sites in Dallas, Austin +16 more locations

Sponsor: Pacific Edge Limited

Sex: All·Age: 18 - 88

Code: NCT06394869·Recruiting·Listed May 2024

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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

for Healthy Volunteers, Pulmonary Arterial Hypertension

Sites in Dallas, Austin +18 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06649110·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

Sites in Dallas +20 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

for Soft Tissue Lesion

Sites in Dallas, Tyler +9 more locations

Sponsor: Galvanize Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05851430·Recruiting·Listed May 2023

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

Sites in Dallas, Fort Worth +20 more locations

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023

Apply to this trial

MEASuRE: Metreleptin Effectiveness And Safety Registry

for Generalised Lipodystrophy

Sites in Dallas +8 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: All ages

Code: NCT02325674·Recruiting·Listed Dec 2014

Apply to this trial

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

Sites in Dallas, Temple +20 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting·Listed Mar 2023

Apply to this trial

A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

Sites in Dallas +9 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting·Listed May 2022

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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

for Complex Cardiovascular Surgery With Cardiopulmonary Bypass

Sites in Dallas +9 more locations

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07094087·Phase 3·Recruiting·Listed Jul 2025

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

Sites in Dallas, Houston +17 more locations

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting·Listed Jan 2019

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A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

for Phenylketonuria (PKU)

Sites in Dallas +10 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT06305234·Recruiting·Listed Mar 2024

Apply to this trial

Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

Sites in Dallas, Houston +17 more locations

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting·Listed Oct 2021

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

Sites in Dallas, Houston +11 more locations

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting·Listed Oct 2024

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A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

for Cystic Fibrosis

Sites in Dallas +12 more locations

Sponsor: ReCode Therapeutics

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT06237335·Phase 2·Recruiting·Listed Feb 2024

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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

for Motor Function

Sites in Dallas +7 more locations

Sponsor: Guerbet

Sex: All·Age: 18 - 64

Code: NCT04373564·Phase 4·Recruiting·Listed May 2020

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A Study of Ocular Toxicity Evaluation and Mitigation During Treatment With Mirvetuximab Soravtansine in Participants With Recurrent Ovarian Cancer With High Folate Receptor-Alpha Expression

for Recurrent Ovarian Cancer

Sites in Dallas +6 more locations

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06365853·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

Sites in Dallas, Houston +20 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting·Listed Jul 2023

Apply to this trial

uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Dallas, Houston +20 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

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A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

for Higher-risk Myelodysplastic Syndromes

Sites in Dallas +13 more locations

Sponsor: Akeso

Sex: All·Age: 18+

Code: NCT06196203·Phase 2·Recruiting·Listed Jan 2024

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Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

for Generalized Lipodystrophy

Sites in Dallas +1 more location

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 2+

Code: NCT07220785·Phase 3·Recruiting·Listed Oct 2025

Apply to this trial

Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

for Familial Partial Lipodystrophy

Sites in Dallas +6 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 13+

Code: NCT06679270·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Infant Formula in Infants and Children With Cow's Milk Allergy

for Cow's Milk Allergy

Sites in Dallas +7 more locations

Sponsor: Abbott Nutrition

Sex: All·Age: 3 Months - 12

Code: NCT06456541·Recruiting·Listed Jun 2024

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Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease

for Metastatic Breast Cancer in the Liver

Sites in Dallas +3 more locations

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06875128·Phase 2·Recruiting·Listed Mar 2025

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A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for Adenocarcinoma of Lung

Sites in Dallas +4 more locations

Sponsor: Lantern Pharma Inc.

Sex: All·Age: 18+

Code: NCT05456256·Phase 2·Recruiting·Listed Jul 2022

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Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

for Severe Hemophilia A

1 location in Dallas

Sponsor: Octapharma

Sex: Male·Age: 12+

Code: NCT05935358·Phase 4·Recruiting·Listed Jul 2023

Apply to this trial

Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

for IGF1 Deficiency

Sites in Dallas +4 more locations

Sponsor: Esteve Pharmaceuticals, S.A.

Sex: All·Age: 2 - 18

Code: NCT00903110·Recruiting·Listed May 2009

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A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

for Advanced Solid Tumor

Sites in Dallas +3 more locations

Sponsor: FBD Biologics Limited

Sex: All·Age: 18+

Code: NCT05892718·Phase 1·Recruiting·Listed Jun 2023

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A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel

for Cerebral Adrenoleukodystrophy (CALD)

Sites in Dallas +2 more locations

Sponsor: Genetix Biotherapeutics Inc.

Sex: Male·Age: All ages

Code: NCT06224413·Recruiting·Listed Jan 2024

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The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

for Lower Respiratory Tract Infection

Sites in Dallas +7 more locations

Sponsor: MeMed Diagnostics Ltd.

Sex: All·Age: 18 - 99

Code: NCT05762302·Recruiting·Listed Mar 2023

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Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Dallas +1 more location

Sponsor: Secretome Therapeutics

Sex: All·Age: 18+

Code: NCT06560762·Phase 1·Recruiting·Listed Aug 2024

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Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

for Glioma

Sites in Dallas, San Antonio +1 more location

Sponsor: Plus Therapeutics

Sex: All·Age: 18+

Code: NCT01906385·Phase 1, Phase 2·Recruiting·Listed Jul 2013

Apply to this trial

Longitudinal Bladder Cancer Study for Tumour Recurrence

for Urothelial Bladder Cancer

Sites in Dallas +5 more locations

Sponsor: Pacific Edge Limited

Sex: All·Age: 18+

Code: NCT05080998·Recruiting·Listed Oct 2021

Apply to this trial

The Return of Cardiovascular Information Trial (RECITE)

for Health Curiosity

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT07613853·Recruiting·Listed May 2026

Apply to this trial

Duchenne Electronic Health Record Study

for Duchenne Muscular Dystrophy (DMD)

Sites in Dallas +9 more locations

Sponsor: The Duchenne Registry

Sex: All·Age: All ages

Code: NCT07609394·Recruiting·Listed May 2026

Apply to this trial

FOCUS Bipolar: Families Opening Conversations for Understanding Signs

for Bipolar Disorder (BD)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07622927·Recruiting·Listed Jun 2026

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Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials

for NPH (Normal Pressure Hydrocephalus)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 60 - 99

Code: NCT07494812·Recruiting·Listed Mar 2026

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Dallas +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

Apply to this trial