Clinical Trials at UT Southwestern Medical Center

As of September 2026, 167 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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169 clinical trials at UT Southwestern Medical Center

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Immune Modulation During Palynziq® Treatment in Adults (IMPALA)

for Phenylketonuria

Sites in Dallas +11 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 18 - 65

Code: NCT07477691·Phase 4·Recruiting·Listed Mar 2026

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Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer

for Gastric Cancer

Sites in Dallas, Tyler +13 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06731478·Phase 3·Recruiting·Listed Dec 2024

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A Clinical Study to Find the Optimal Dose of an Investigational Treatment Called BNT323 When Used in Combination With Another Investigational Treatment, BNT327, and to Test if That Combination Treatment is Safe and Beneficial for Patients With Advanced Breast Cancer

for Locally Advanced Breast Cancer

Sites in Dallas, San Antonio +25 more locations

Sponsor: BioNTech SE

Sex: All·Age: 18+

Code: NCT06827236·Phase 1, Phase 2·Recruiting·Listed Feb 2025

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

Sites in Dallas, Fort Worth +19 more locations

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting·Listed Sep 2023

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

Sites in Dallas +20 more locations

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting·Listed Jan 2025

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Efficacy and Safety of 4F-PCC (4-Factor Prothrombin Complex Concentrate) in Adult Patients Undergoing Complex Cardiovascular Surgery With Cardiopulmonary Bypass (CPB)

for Complex Cardiovascular Surgery With Cardiopulmonary Bypass

Sites in Dallas +15 more locations

Sponsor: CSL Behring

Sex: All·Age: 18+

Code: NCT07094087·Phase 3·Recruiting·Listed Jul 2025

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A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer

for Gastric Adenocarcinoma

Sites in Dallas +9 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT05365581·Phase 1·Recruiting·Listed May 2022

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A Study to Learn About the Treatment LTP001 in Healthy Participants (Part A) and in Participants With PAH (Part B)

for Healthy Volunteers, Pulmonary Arterial Hypertension

Sites in Dallas, Austin +18 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06649110·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Study to Assess the Impact of the Urine Test Cxbladder Triage Plus on the Number of Cystoscopies Performed on Patients With Invisible Blood in Their Urine.

for Hematuria - Cause Not Known

Sites in Dallas, Austin +16 more locations

Sponsor: Pacific Edge Limited

Sex: All·Age: 18 - 88

Code: NCT06394869·Recruiting·Listed May 2024

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MEASuRE: Metreleptin Effectiveness And Safety Registry

for Generalised Lipodystrophy

Sites in Dallas +8 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: All ages

Code: NCT02325674·Recruiting·Listed Dec 2014

Apply to this trial

Galvanize Prospective/Retrospective Pulsed Electric Field Device Registry

for Soft Tissue Lesion

Sites in Dallas, Tyler +9 more locations

Sponsor: Galvanize Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05851430·Recruiting·Listed May 2023

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Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

for IC-MPGN

Drug: Iptacopan

Sites in Dallas, Temple +20 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT05755386·Phase 3·Recruiting·Listed Mar 2023

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

Sites in Dallas, Houston +17 more locations

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting·Listed Jan 2019

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A Long Term, Post-marketing Study of Immune Response in Patients Receiving Palynziq Treatment for PKU (PALisade)

for Phenylketonuria (PKU)

Sites in Dallas +10 more locations

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: All ages

Code: NCT06305234·Recruiting·Listed Mar 2024

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Study of ONO-4685 in Patients With Relapsed or Refractory T Cell Lymphoma

for Relapsed or Refractory T Cell Lymphoma

Sites in Dallas, Houston +17 more locations

Sponsor: Ono Pharmaceutical Co., Ltd.

Sex: All·Age: 18+

Code: NCT05079282·Phase 1·Recruiting·Listed Oct 2021

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A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

for Muscular Diseases

Sites in Dallas, Houston +11 more locations

Sponsor: Arcellx, Inc.

Sex: All·Age: 18+

Code: NCT06626919·Phase 1·Recruiting·Listed Oct 2024

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Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

for Motor Function

Sites in Dallas +7 more locations

Sponsor: Guerbet

Sex: All·Age: 18 - 64

Code: NCT04373564·Phase 4·Recruiting·Listed May 2020

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US National OCS Liver Perfusion (OLP) Registry

for Liver Transplant

Sites in Dallas, Houston +20 more locations

Sponsor: TransMedics

Sex: All·Age: All ages

Code: NCT05940857·Recruiting·Listed Jul 2023

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uTRACT Jelmyto Registry: A Registry of Patients With Upper Tract Urothelial Cancer (UTUC) Treated With Jelmyto

for Urothelial Carcinoma

Sites in Dallas, Houston +20 more locations

Sponsor: UroGen Pharma Ltd.

Sex: All·Age: 18+

Code: NCT05874921·Recruiting·Listed May 2023

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A Study of AK117 in Combination With Azacitidine in Patients With Myelodysplastic Syndromes

for Higher-risk Myelodysplastic Syndromes

Sites in Dallas +13 more locations

Sponsor: Akeso

Sex: All·Age: 18+

Code: NCT06196203·Phase 2·Recruiting·Listed Jan 2024

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An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)

for Pulmonary Arterial Hypertension

Sites in Dallas +14 more locations

Sponsor: Inhibikase Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07365332·Phase 3·Recruiting·Listed Jan 2026

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Efficacy and Safety of Mibavademab in Adult and Pediatric Patients With Generalized Lipodystrophy

for Generalized Lipodystrophy

Sites in Dallas +1 more location

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 2+

Code: NCT07220785·Phase 3·Recruiting·Listed Oct 2025

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Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU

for Non Hodgkin Lymphoma

Sites in Dallas +10 more locations

Sponsor: Miltenyi Biomedicine GmbH

Sex: All·Age: 18+

Code: NCT06116110·Recruiting·Listed Nov 2023

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Open-label Extension Study to Evaluate Metreleptin in Patients With Partial Lipodystrophy

for Familial Partial Lipodystrophy

Sites in Dallas +6 more locations

Sponsor: Chiesi Farmaceutici S.p.A.

Sex: All·Age: 13+

Code: NCT06679270·Phase 3·Recruiting·Listed Nov 2024

Apply to this trial

Infant Formula in Infants and Children With Cow's Milk Allergy

for Cow's Milk Allergy

Sites in Dallas +7 more locations

Sponsor: Abbott Nutrition

Sex: All·Age: 3 Months - 12

Code: NCT06456541·Recruiting·Listed Jun 2024

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A Study of Lonitoclax (ZE50-0134) in Relapsed or Refractory B-cell Malignancies

for CLL / SLL

Sites in Dallas +4 more locations

Sponsor: Lomond Therapeutics Holdings, Inc.

Sex: All·Age: 18+

Code: NCT06708897·Phase 1·Recruiting·Listed Nov 2024

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Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Breast Cancer w/Liver Dominant Disease

for Metastatic Breast Cancer in the Liver

Sites in Dallas +3 more locations

Sponsor: Delcath Systems Inc.

Sex: All·Age: 18+

Code: NCT06875128·Phase 2·Recruiting·Listed Mar 2025

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A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

for Adenocarcinoma of Lung

Sites in Dallas +4 more locations

Sponsor: Lantern Pharma Inc.

Sex: All·Age: 18+

Code: NCT05456256·Phase 2·Recruiting·Listed Jul 2022

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Global Patient Registry to Monitor Long-term Safety and Effectiveness of Increlex® in Children and Adolescents With Severe Primary Insulin-like Growth Factor-1 Deficiency (SPIGFD).

for IGF1 Deficiency

Sites in Dallas +4 more locations

Sponsor: Esteve Pharmaceuticals, S.A.

Sex: All·Age: 2 - 18

Code: NCT00903110·Recruiting·Listed May 2009

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A Safety and Efficacy Study of HCB101, Fc-fusion Protein Targeting SIRPα-CD47 Pathway, in Solid or Hematological Tumors

for Advanced Solid Tumor

Sites in Dallas +3 more locations

Sponsor: FBD Biologics Limited

Sex: All·Age: 18+

Code: NCT05892718·Phase 1·Recruiting·Listed Jun 2023

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A Study of Participants With Cerebral Adrenoleukodystrophy (CALD) Treated With Elivaldogene Autotemcel

for Cerebral Adrenoleukodystrophy (CALD)

Sites in Dallas +2 more locations

Sponsor: Genetix Biotherapeutics Inc.

Sex: Male·Age: All ages

Code: NCT06224413·Recruiting·Listed Jan 2024

Apply to this trial

Nuwiq for Perioperative Management Of Patients With Haemophilia A on Emicizumab Regular Prophylaxis Study

for Severe Hemophilia A

1 location in Dallas

Sponsor: Octapharma

Sex: Male·Age: 12+

Code: NCT05935358·Phase 4·Recruiting·Listed Jul 2023

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The Impact of MeMed BV® on Management of Patients With Suspected Lower Respiratory Tract Infections (LRTI) in the Emergency Department (ED) and Urgent Care Center (UCC) ("JUPITER" TRIAL)

for Lower Respiratory Tract Infection

Sites in Dallas +7 more locations

Sponsor: MeMed Diagnostics Ltd.

Sex: All·Age: 18 - 99

Code: NCT05762302·Recruiting·Listed Mar 2023

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Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Dallas +1 more location

Sponsor: Secretome Therapeutics

Sex: All·Age: 18+

Code: NCT06560762·Phase 1·Recruiting·Listed Aug 2024

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Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

for Glioma

Sites in Dallas, San Antonio +1 more location

Sponsor: Cerenome

Sex: All·Age: 18+

Code: NCT01906385·Phase 1, Phase 2·Recruiting·Listed Jul 2013

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Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer

for Bladder Cancer

1 location in Dallas

Sponsor: Convergent Genomics, Inc.

Sex: All·Age: 18+

Code: NCT07673016·Recruiting·Listed Jun 2026

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Prospective Investigation of Cirrhotic Cardiomyopathy in Humans

for Cirrhotic Cardiomyopathy

Sites in Dallas +1 more location

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: 18+

Code: NCT07658222·Recruiting·Listed Jun 2026

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The Return of Cardiovascular Information Trial (RECITE)

for Health Curiosity

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 35+·Accepts healthy volunteers

Code: NCT07613853·Recruiting·Listed May 2026

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FOCUS Bipolar: Families Opening Conversations for Understanding Signs

for Bipolar Disorder (BD)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07622927·Recruiting·Listed Jun 2026

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Duchenne Electronic Health Record Study

for Duchenne Muscular Dystrophy (DMD)

Sites in Dallas +9 more locations

Sponsor: The Duchenne Registry

Sex: All·Age: All ages

Code: NCT07609394·Recruiting·Listed May 2026

Apply to this trial