Clinical Trials at UT Southwestern Medical Center

As of September 2026, 167 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 21, 2026.

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169 clinical trials at UT Southwestern Medical Center

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Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials

for NPH (Normal Pressure Hydrocephalus)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 60 - 99

Code: NCT07494812·Recruiting·Listed Mar 2026

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Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)

for PSC

Sites in Dallas +10 more locations

Sponsor: PSC Partners Seeking a Cure

Sex: All·Age: 18 - 75

Code: NCT06297993·Recruiting·Listed Mar 2024

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A Randomized Multicenter Study for Isolated Skin Vasculitis

for Primary Cutaneous Vasculitis

Sites in Dallas +3 more locations

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02939573·Phase 2·Recruiting·Listed Oct 2016

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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials

for Stroke

Sites in Dallas, Houston +38 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05338697·Recruiting·Listed Apr 2022

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Treatment of Inflammatory Myelitis and Optic Neuritis With Early vs Rescue Plasma Exchange (TIMELY-PLEX)

for Optic Neuritis

Sites in Dallas +28 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT07100990·Phase 3·Recruiting·Listed Aug 2025

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A-LiNK: Improving Outcomes in Autoimmune Liver Disease

for Autoimmune Hepatitis

Sites in Dallas +7 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: All ages

Code: NCT05750498·Recruiting·Listed Mar 2023

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Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM)

for Small Cell Lung Cancer Extensive Stage

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07139990·Phase 1·Recruiting·Listed Aug 2025

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Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer

for Bladder Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06394570·Phase 1, Phase 2·Recruiting·Listed May 2024

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Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for Non-muscle-invasive Bladder Cancer

Sites in Dallas +7 more locations

Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT05796375·Phase 2·Recruiting·Listed Apr 2023

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Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

for Obstructive Sleep Apnea

Sites in Dallas, Houston +4 more locations

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT05508971·Recruiting·Listed Aug 2022

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Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

for Prostate Cancer Screening

Sites in Dallas +1 more location

Sponsor: University of Alberta

Sex: Male·Age: 50 - 70·Accepts healthy volunteers

Code: NCT06626022·Phase 3·Recruiting·Listed Oct 2024

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Dallas, Austin +32 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

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Accelerated rTMS for Substance Use Disorder and Depression

for Stimulant Use

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65

Code: NCT06424184·Recruiting·Listed May 2024

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Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

for AL Amyloidosis

Drug: Belantamab mafodotin

Sites in Dallas +2 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05145816·Phase 1, Phase 2·Recruiting·Listed Dec 2021

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Dallas, Bellaire +25 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Dallas, Houston +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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Polypill for Prevention of Cardiomyopathy

for Type 2 Diabetes

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 100

Code: NCT06143566·Phase 1, Phase 2·Recruiting·Listed Nov 2023

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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sites in Dallas, San Antonio +18 more locations

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting·Listed May 2024

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Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections

for Recurrent UTIs

Sites in Dallas +1 more location

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 18 - 85

Code: NCT06907199·Phase 1·Recruiting·Listed Apr 2025

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Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia

for Type 1 Hyperlipoprotenemia

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 8+

Code: NCT05816343·Phase 2·Recruiting·Listed Apr 2023

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Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

Sites in Dallas, Houston +27 more locations

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting·Listed Apr 2024

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Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

for Unspecified Adult Solid Tumor, Protocol Specific

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00992303·Recruiting·Listed Oct 2009

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Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

for Postural Orthostatic Tachycardia Syndrome

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT06292104·Recruiting·Listed Mar 2024

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CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for HER2-negative Breast Cancer

Sites in Dallas, San Antonio +3 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05029999·Phase 1·Recruiting·Listed Sep 2021

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Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

for Treatment Resistant Depression

1 location in Dallas

Sponsor: Nader Pouratian

Sex: All·Age: 21 - 70

Code: NCT03952962·Recruiting·Listed May 2019

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Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Sites in Dallas, Houston +1 more location

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting·Listed Feb 2014

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Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

for Traumatic Brain Injury With Loss of Consciousness

3 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 80

Code: NCT06480838·Recruiting·Listed Jun 2024

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MTOR Inhibitors in Older Adults

for Aging

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT06727305·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

Sites in Dallas +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting·Listed Jan 2025

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Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

for Prostate Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 40 - 89

Code: NCT03769766·Phase 3·Recruiting·Listed Dec 2018

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Patients With and Without Phonotrauma

for Phonotrauma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05625191·Recruiting·Listed Nov 2022

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Deep Brain Stimulation for Psychosis

for Treatment-Refractory Schizophrenia

1 location in Dallas

Sponsor: Bradley Lega

Sex: All·Age: 22 - 70

Code: NCT06257056·Recruiting·Listed Feb 2024

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CLOZAPINE Response in Biotype-1

for Schizophrenia

Sites in Dallas +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting·Listed Oct 2020

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Dallas, Plano +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

for Renal Cell Carcinoma

Drug: Nivolumab

Sites in Dallas, Houston +4 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06053658·Phase 2·Recruiting·Listed Sep 2023

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Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

for Calcium Phosphate Kidney Stones

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 21 - 99

Code: NCT06003348·Phase 4·Recruiting·Listed Aug 2023

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The Unlocking PrEP Study: Integration of Peer Health Navigation Into Comprehensive Re-entry Services

for HIV Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07292792·Recruiting·Listed Dec 2025

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Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery

for Stage II Rectal Cancer

1 location in Dallas

Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: All·Age: 18 - 80

Code: NCT03051464·Phase 2, Phase 3·Recruiting·Listed Feb 2017

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Motor Network Physiology

for Parkinson Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 89

Code: NCT04957095·Recruiting·Listed Jul 2021

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Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

for Post Operative Pain

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06158620·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial