Clinical Trials at UT Southwestern Medical Center

As of July 2026, 159 paid clinical trials are recruiting at UT Southwestern Medical Center, located at UT Southwestern Medical Center: Research Department, 6000 Harry Hines Blvd, Dallas, TX 75235, phone (214) 633-0022 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

162 clinical trials at UT Southwestern Medical Center

·Clear filters·

Chronic Subdural Hematoma Treatment With Embolization Versus Surgery Study

for Chronic Subdural Hematoma

Sites in Dallas, Houston +27 more locations

Sponsor: The University of Texas Medical Branch, Galveston

Sex: All·Age: 40 - 90

Code: NCT06347796·Recruiting·Listed Apr 2024

Apply to this trial

Bionic Pancreas in CFRD

for Cystic Fibrosis-related Diabetes

Sites in Dallas, Houston +13 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 14+

Code: NCT06449677·Phase 3·Recruiting·Listed Jun 2024

Apply to this trial

Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)

for PSC

Sites in Dallas +10 more locations

Sponsor: PSC Partners Seeking a Cure

Sex: All·Age: 18 - 75

Code: NCT06297993·Recruiting·Listed Mar 2024

Apply to this trial

Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Dallas, Houston +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

Apply to this trial

CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer

for HER2-negative Breast Cancer

Sites in Dallas, San Antonio +3 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05029999·Phase 1·Recruiting·Listed Sep 2021

Apply to this trial

The Unlocking PrEP Study: Integration of Peer Health Navigation Into Comprehensive Re-entry Services

for HIV Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07292792·Recruiting·Listed Dec 2025

Apply to this trial

Daily Nitrofurantoin Versus Bladder Fulguration Plus Daily Nitrofurantoin for Women With Recurrent Urinary Tract Infections

for Recurrent UTIs

Sites in Dallas +1 more location

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 18 - 85

Code: NCT06907199·Phase 1·Recruiting·Listed Apr 2025

Apply to this trial

Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sites in Dallas, San Antonio +16 more locations

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting·Listed May 2024

Apply to this trial

Long Term Efficacy and Safety of Orlistat for Type 1 Hyperlipoproteinemia

for Type 1 Hyperlipoprotenemia

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 8+

Code: NCT05816343·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)

for Postural Orthostatic Tachycardia Syndrome

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 14+·Accepts healthy volunteers

Code: NCT06292104·Recruiting·Listed Mar 2024

Apply to this trial

Collecting Tissue Samples From Patients With Cancer Undergoing Radiation Therapy and Healthy Participants

for Unspecified Adult Solid Tumor, Protocol Specific

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00992303·Recruiting·Listed Oct 2009

Apply to this trial

Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Dallas, Bellaire +23 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Study of Orally Administered AG-120 in Subjects With Advanced Hematologic Malignancies With an IDH1 Mutation

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

Sites in Dallas, Houston +1 more location

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT02074839·Phase 1·Recruiting·Listed Feb 2014

Apply to this trial

Tractography Guided Subcallosal Cingulate Deep Brain Stimulation for Treatment Resistant Depression

for Treatment Resistant Depression

1 location in Dallas

Sponsor: Nader Pouratian

Sex: All·Age: 21 - 70

Code: NCT03952962·Recruiting·Listed May 2019

Apply to this trial

Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

for Obstructive Sleep Apnea

Sites in Dallas, Houston +4 more locations

Sponsor: Oregon Health and Science University

Sex: All·Age: 2 - 17

Code: NCT05508971·Recruiting·Listed Aug 2022

Apply to this trial

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

Sites in Dallas +8 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting·Listed Jan 2025

Apply to this trial

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

for Traumatic Brain Injury With Loss of Consciousness

3 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 80

Code: NCT06480838·Recruiting·Listed Jun 2024

Apply to this trial

MTOR Inhibitors in Older Adults

for Aging

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT06727305·Phase 1, Phase 2·Recruiting·Listed Dec 2024

Apply to this trial

Trial of Curcumin to Prevent Progression of Low-risk Prostate Cancer Under Active Surveillance

for Prostate Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 40 - 89

Code: NCT03769766·Phase 3·Recruiting·Listed Dec 2018

Apply to this trial

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Dallas, Plano +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

Apply to this trial

CLOZAPINE Response in Biotype-1

for Schizophrenia

Sites in Dallas +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting·Listed Oct 2020

Apply to this trial

Patients With and Without Phonotrauma

for Phonotrauma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT05625191·Recruiting·Listed Nov 2022

Apply to this trial

Deep Brain Stimulation for Psychosis

for Treatment-Refractory Schizophrenia

1 location in Dallas

Sponsor: Bradley Lega

Sex: All·Age: 22 - 70

Code: NCT06257056·Recruiting·Listed Feb 2024

Apply to this trial

Phase 2 Study of Combination Tivozanib and Nivolumab in Advanced Non-Clear Cell Renal Cell Carcinoma

for Renal Cell Carcinoma

Drug: Nivolumab

Sites in Dallas, Houston +4 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06053658·Phase 2·Recruiting·Listed Sep 2023

Apply to this trial

Screening for Prostate Cancer Using High Resolution Micro-ultrasound Versus Multiparametric Magnetic Resonance Imaging.

for Prostate Cancer Screening

Sites in Dallas +1 more location

Sponsor: University of Alberta

Sex: Male·Age: 50 - 70·Accepts healthy volunteers

Code: NCT06626022·Phase 3·Recruiting·Listed Oct 2024

Apply to this trial

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

for Calcium Phosphate Kidney Stones

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 21 - 99

Code: NCT06003348·Phase 4·Recruiting·Listed Aug 2023

Apply to this trial

Randomizing Two Radiotherapy Boost Options to Avoid Rectal Cancer Surgery

for Stage II Rectal Cancer

1 location in Dallas

Sponsor: Sir Mortimer B. Davis - Jewish General Hospital

Sex: All·Age: 18 - 80

Code: NCT03051464·Phase 2, Phase 3·Recruiting·Listed Feb 2017

Apply to this trial

Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone Disease

for Post Operative Pain

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06158620·Phase 1, Phase 2·Recruiting·Listed Dec 2023

Apply to this trial

Multiple System Atrophy Multidisciplinary Clinic

for Multiple System Atrophy (MSA)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT03811808·Recruiting·Listed Jan 2019

Apply to this trial

The Role of Sirolimus in Preventing Functional Decline in Older Adults

for Aging

1 location in Dallas

Sponsor: Irina Timofte

Sex: All·Age: 65 - 80·Accepts healthy volunteers

Code: NCT05237687·Phase 2·Recruiting·Listed Feb 2022

Apply to this trial

Lupus Landmark Study: A Prospective Registry and Biorepository

for Systemic Lupus Erythematosus (SLE)

Sites in Dallas +18 more locations

Sponsor: Lupus Research Alliance

Sex: All·Age: 18 - 110

Code: NCT05934149·Recruiting·Listed Jul 2023

Apply to this trial

Motor Network Physiology

for Parkinson Disease

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 89

Code: NCT04957095·Recruiting·Listed Jul 2021

Apply to this trial

Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes

for Heart Failure

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages

Code: NCT06593314·Recruiting·Listed Sep 2024

Apply to this trial

Phase 1/2a Study of Belantamab Mafodotin in Relapsed or Refractory AL Amyloidosis

for AL Amyloidosis

Drug: Belantamab mafodotin

Sites in Dallas +2 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT05145816·Phase 1, Phase 2·Recruiting·Listed Dec 2021

Apply to this trial

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

for Heart Failure With Preserved Ejection Fraction

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 55 - 90·Accepts healthy volunteers

Code: NCT05723679·Recruiting·Listed Feb 2023

Apply to this trial

Replacing Invasive Cystoscopy With Urine Testing for Non-muscle Invasive Bladder Cancer Surveillance

for Non-muscle-invasive Bladder Cancer

Sites in Dallas +7 more locations

Sponsor: White River Junction Veterans Affairs Medical Center

Sex: All·Age: 18+

Code: NCT05796375·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Study of Pembrolizumab and Lenvatinib in Metastatic and Recurrent Cervix Cancer (LenPem Cervix)

for Cervix Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 18+

Code: NCT06266338·Phase 2·Recruiting·Listed Feb 2024

Apply to this trial

Markers of Osteoporosis in Cystic Fibrosis

for Cystic Fibrosis

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT03921060·Phase 4·Recruiting·Listed Apr 2019

Apply to this trial

Multiparametric Image Analysis and Correlation With Outcomes in Lung Cancer Screening and Early Stage Lung Cancer

for Lung Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT03563976·Recruiting·Listed Jun 2018

Apply to this trial

Invert-Prospective Phase II Randomized Trial of Involved Nodal Versus Elective Neck RadioTherapy

for Head and Neck Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT06477692·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial