Clinical Trials at University of Texas Southwestern Medical Center

As of July 2026, 163 paid clinical trials are recruiting at University of Texas Southwestern Medical Center, located at 5323 HARRY HINES BLVD, DALLAS, TX 75390, phone (214) 648-7833 in Dallas, Texas. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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164 clinical trials at University of Texas Southwestern Medical Center

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A Trial of Robotic Versus Open Hysterectomy Surgery in Cervix Cancer

for Cervical Cancer

Sites in Dallas, Bedford +115 more locations

Sponsor: GOG Foundation

Sex: Female·Age: 18+

Code: NCT04831580·Recruiting·Listed Apr 2021

Apply to this trial

Phosphate Assessment in Chronic Kidney Disease Patients Study

for Chronic Kidney Disease (Stage 3-4)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07368946·Recruiting·Listed Jan 2026

Apply to this trial

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

for Hematologic Malignancies

Sites in Dallas, Fort Worth +111 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: All ages

Code: NCT01351545·Recruiting·Listed May 2011

Apply to this trial

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

for Liver Transplant

Sites in Dallas +16 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT06075745·Phase 2·Recruiting·Listed Oct 2023

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Accelerometer Measured Early Recovery After Prolapse Surgery

for Pelvic Organ Prolapse

Sites in Dallas +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 18 - 99

Code: NCT07218016·Recruiting·Listed Oct 2025

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Ocrelizumab Discontinuation in Relapsing Multiple Sclerosis

for Multiple Sclerosis

Sites in Dallas, Houston +11 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 55

Code: NCT05285891·Phase 4·Recruiting·Listed Mar 2022

Apply to this trial

Intrathecal Gene Therapy For SLC13A5 Citrate Transporter Disorder

for SLC13A5 Citrate Transporter Disorder

1 location in Dallas

Sponsor: TESS Research Foundation

Sex: All·Age: 2 - 20

Code: NCT07102524·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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Trametinib and Everolimus for Treatment of Pediatric and Young Adult Patients With Recurrent Gliomas (PNOC021)

for Recurrent World Health Organization (WHO) Grade II Glioma

Drug: Trametinib

Sites in Dallas +14 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 1 - 25

Code: NCT04485559·Phase 1·Recruiting·Listed Jul 2020

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A Polypill for Acute Coronary Syndrome

for Acute Coronary Syndrome

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT07032389·Phase 2·Recruiting·Listed Jun 2025

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Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

for Small Bowel Adenocarcinoma

Sites in Dallas +6 more locations

Sponsor: Tiago Biachi de Castria

Sex: All·Age: 18+

Code: NCT06835387·Phase 2·Recruiting·Listed Feb 2025

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Extending Outcomes for Pancreas Cancer Patients With Nominal Oligometastatic Disease (EXPAND): A Randomized Phase III Trial

for Pancreas Cancer

Sites in Dallas, Houston +2 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06593431·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial

UTSW NORC Pilot Spinal Cord Injury Dietary Program

for Obesity and Obesity-related Medical Conditions

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65

Code: NCT06924177·Recruiting·Listed Apr 2025

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Cancer Clinical Trials Financial Reimbursement Program

for Cancer Clinical Trials

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: All ages

Code: NCT05402033·Recruiting·Listed Jun 2022

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Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

for Mild Cognitive Impairment

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 55+

Code: NCT05446584·Phase 2·Recruiting·Listed Jul 2022

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Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

for Large Cell Lymphoma, Diffuse

Drug: Epcoritamab

Sites in Dallas +3 more locations

Sponsor: Dipenkumar Modi

Sex: All·Age: 18+

Code: NCT05852717·Phase 2·Recruiting·Listed May 2023

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Zanubrutinib, Bendamustine, Rituximab Prev. Untreated WM

for Waldenstrom Macroglobulinemia

Drug: Rituximab

Sites in Dallas +4 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06561347·Phase 2·Recruiting·Listed Aug 2024

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CEUS vs. AMRI for HCC Detection in Patients With Indeterminate Liver Nodules

for HCC

Sites in Dallas +1 more location

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06184152·Recruiting·Listed Dec 2023

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Feasibility Study of Personalized Ultra-fractionated Stereotactic Ablative Radiotherapy (PULSAR) for Cancers of the Central Lung

for Cancer, Lung

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06712745·EARLY_Phase 1·Recruiting·Listed Dec 2024

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MINT Conditioning to Improve Gait

for Stroke

Sites in Dallas +1 more location

Sponsor: Northwestern University

Sex: All·Age: 18 - 85

Code: NCT07041775·Recruiting·Listed Jun 2025

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Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

for Amyloidosis, Hereditary

Sites in Dallas +2 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 30 - 80

Code: NCT05489549·Recruiting·Listed Aug 2022

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Dallas, Austin +85 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Single Cell Immune and Non-immune Correlates of Response to Neoadjuvant Abemaciclib

for Breast Cancer

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Female·Age: 18+

Code: NCT04614194·Phase 2·Recruiting·Listed Nov 2020

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Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

Sites in Dallas +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting·Listed Jun 2024

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Neoadjuvant Zanzalintinib Plus Nivolumab in Patients With Locally Advanced and/or Inoperable Clear Cell Renal Cell Carcinoma With or Without Non-measurable Metastasis

for Locally Advanced Renal Cell Carcinoma

Drug: Nivolumab

Sites in Dallas +2 more locations

Sponsor: Qian Qin

Sex: All·Age: 18+

Code: NCT06794229·Phase 2·Recruiting·Listed Jan 2025

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External Lumbar Drainage to Reduce ICP in Severe TBI: a Phase 1 Clinical Trial

for Severe Traumatic Brain Injury

Sites in Dallas, Houston +4 more locations

Sponsor: Brain Trauma Foundation

Sex: All·Age: 18 - 65

Code: NCT05889650·Recruiting·Listed Jun 2023

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Identification of Metabolic Phenotypes Associated With Melanoma Metastasis

for Melanoma (Skin)

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06400550·Recruiting·Listed May 2024

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A Randomized Phase 2 Trial of Nivolumab, Relatlimab Plus Ipilimumab vs. Nivolumab Plus Ipilimumab in First-line Advanced Renal Cell Carcinoma (RCC)

for Renal Cell Carcinoma, Clear Cell

Drug: Ipilimumab

Sites in Dallas, Houston +4 more locations

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: 18+

Code: NCT06708949·Phase 2·Recruiting·Listed Nov 2024

Apply to this trial

Home-based Cardiac Rehabilitation in Heart Failure

for Heart Failure

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06349941·Phase 3·Recruiting·Listed Apr 2024

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Comparison of Uncomplicated Candidemia Therapy Duration in Children

for Invasive Candidiasis

Sites in Dallas, Austin +19 more locations

Sponsor: Arkansas Children's Hospital Research Institute

Sex: All·Age: 120 Days+

Code: NCT05763251·Recruiting·Listed Mar 2023

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Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

for Drug Allergy

Sites in Dallas +5 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 70

Code: NCT06406114·Phase 2·Recruiting·Listed May 2024

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IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

for Non Hodgkin Lymphoma

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT06768905·Phase 1, Phase 2·Recruiting·Listed Jan 2025

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JoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung Cancer

for Non-Small Cell Lung Cancer

Sites in Dallas +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT02468024·Phase 3·Recruiting·Listed Jun 2015

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Deep Brain Stimulation for Refractory Obsessive-Compulsive Disorder

for Obsessive-Compulsive Disorder

1 location in Dallas

Sponsor: Nader Pouratian

Sex: All·Age: 22 - 75

Code: NCT06660225·Recruiting·Listed Oct 2024

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Cool Prime Comparative Effectiveness Study for Mild HIE

for Mild Hypoxic Ischemic Encephalopathy of Newborn

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 36 Weeks+

Code: NCT04621279·Recruiting·Listed Nov 2020

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Sickle Cell Kidney Biorepository

for Sickle Cell Trait

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07064174·Recruiting·Listed Jul 2025

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Metabolic Biomarkers in Thoracic Cancers

for Lung Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18+

Code: NCT02095808·Recruiting·Listed Mar 2014

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Bladder Cancer Screening Trial

for Bladder Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 50+

Code: NCT05646485·Recruiting·Listed Dec 2022

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Database Registry for Neural Network Biomarkers in Psychosis

for Schizophrenia

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT01409109·Recruiting·Listed Aug 2011

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A Phase 2a, Single-dose, Open-label Study to Evaluate Diagnostic Performance and Safety of Pegsitacianine, an Intraoperative Fluorescence Imaging Agent for the Detection of Cancer, in Patients With Unknown Primary Head and Neck Cancer (ILLUMINATE STUDY)

for Head and Neck Cancer

1 location in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 99

Code: NCT05576974·Phase 2·Recruiting·Listed Oct 2022

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PSMA PET Response Guided SabR in High Risk Pca

for Prostate Adenocarcinoma

2 locations in Dallas

Sponsor: University of Texas Southwestern Medical Center

Sex: Male·Age: 18 - 99

Code: NCT06044857·Phase 1·Recruiting·Listed Sep 2023

Apply to this trial