Paid Clinical Trials in Detroit, MI

As of September 2026, 708 paid clinical trials are recruiting in Detroit, Michigan. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

654 clinical trials

Get a weekly email when new trials open in Detroit, MI.

Follow-up Visit of High Risk Infants

for Infant, Newborn

Sites in Detroit +18 more locations

Sponsor: NICHD Neonatal Research Network

Sex: All·Age: 18 Months - 26 Months

Code: NCT00009633·Recruiting·Listed Feb 2001

Apply to this trial

Family Intervention for Black Teens With Type 1 Diabetes

for Type 1 Diabetes

Sites in Detroit +3 more locations

Sponsor: Wayne State University

Sex: All·Age: 10 - 14

Code: NCT06275412·Recruiting·Listed Feb 2024

Apply to this trial

ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Detroit +75 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

Apply to this trial

Sleep Apnea in Elderly

for Sleep Apnea

1 location in Detroit

Sponsor: VA Office of Research and Development

Sex: All·Age: 60 - 89·Accepts healthy volunteers

Code: NCT02703220·Phase 4·Recruiting·Listed Mar 2016

Apply to this trial

Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)

for Patient Satisfaction

Sites in Detroit +5 more locations

Sponsor: Minneapolis Heart Institute Foundation

Sex: All·Age: 18+

Code: NCT04077762·Recruiting·Listed Sep 2019

Apply to this trial

Prevention of Bleeding in Patients With Moderate and Severe Hemophilia A Playing Sports: A Comparison Between Factor VIII and Emicizumab Prophylaxis

for Hemophilia A

Sites in Detroit +9 more locations

Sponsor: Wayne State University

Sex: All·Age: 6 - 19

Code: NCT05022459·Recruiting·Listed Aug 2021

Apply to this trial

Anterior Cruciate Ligament Recovery With Virtual Psychological Intervention

for Depression

1 location in Detroit

Sponsor: Henry Ford Health System

Sex: All·Age: 13+

Code: NCT05965310·Recruiting·Listed Jul 2023

Apply to this trial

Integrating the Youth Nominated Support Team (YST) With CBT for Black Youth With Acute Suicide Risk: Aim 2b

for Suicide Prevention

2 locations in Detroit

Sponsor: University of Michigan

Sex: All·Age: 12+

Code: NCT07506460·Recruiting·Listed Apr 2026

Apply to this trial

FOCUS ON US: Adapting the FOCUS Program for Sexual and Gender Minority (SGM) Cancer Patients and Caregivers

for Cancer Support

Sites in Detroit +1 more location

Sponsor: Charles Kamen

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT06800053·Recruiting·Listed Jan 2025

Apply to this trial

The Fourth Left Atrial Appendage Occlusion Study

for Atrial Fibrillation

Sites in Detroit, Ann Arbor +45 more locations

Sponsor: Hamilton Health Sciences Corporation

Sex: All·Age: 18+

Code: NCT05963698·Recruiting·Listed Jul 2023

Apply to this trial

Clarifying the Optimal Application of SLT Therapy Trial

for Glaucoma and Ocular Hypertension

Sites in Detroit, Ann Arbor +25 more locations

Sponsor: University of Pittsburgh

Sex: All·Age: 18+

Code: NCT04967989·Phase 3·Recruiting·Listed Jul 2021

Apply to this trial

Mild Intermittent Hypoxia: A Prophylactic for Autonomic Dysfunction in Individuals With Spinal Cord Injuries

for Spinal Cord Injuries

1 location in Detroit

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 60

Code: NCT05351827·Recruiting·Listed Apr 2022

Apply to this trial

Metformin Combined With Chemotherapy and/or Immunotherapy in Solid Malignancies

for Advanced Solid Tumor

Sites in Detroit, Macomb +8 more locations

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All·Age: 18+

Code: NCT07098299·Phase 1·Recruiting·Listed Aug 2025

Apply to this trial

S1703 Serum Tumor Marker Directed Disease Monitoring in Patients With Hormone Receptor Positive Her2 Negative Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Detroit, Warren +584 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03723928·Recruiting·Listed Oct 2018

Apply to this trial

Gemcitabine, Nab-paclitaxel Plus the TheraBionic P1 (an Amplitude-Modulated Radiofrequency Electromagnetic Fields) Device to Treat Metastatic Pancreatic Cancer

for Metastatic Pancreatic Adenocarcinoma

Sites in Detroit, Clarkston +5 more locations

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All·Age: 18+

Code: NCT06576115·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Detroit, Ann Arbor +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

Apply to this trial

SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

for Oropharyngeal Cancer

Sites in Detroit, Ann Arbor +21 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT05451004·Phase 3·Recruiting·Listed Jul 2022

Apply to this trial

Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Detroit, Ann Arbor +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

Apply to this trial

Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers

for Post Traumatic Stress Disorder

Sites in Detroit, Ann Arbor +9 more locations

Sponsor: University of Michigan

Sex: All·Age: 18+

Code: NCT05751473·Recruiting·Listed Mar 2023

Apply to this trial

Vascular Trial Associated Registry Pilot

for Peripheral Arterial Disease

Sites in Detroit & Grand Rapids

Sponsor: Corewell Health West

Sex: All·Age: 45+

Code: NCT07076082·Phase 4·Recruiting·Listed Jul 2025

Apply to this trial

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

Sites in Detroit, Dearborn +241 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment

for Sleep Disordered Breathing

1 location in Detroit

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04118387·Phase 4·Recruiting·Listed Oct 2019

Apply to this trial

UPBEAT: Using Polygenic Scores to Guide BB Therapy in HF With Mildly Reduced EF

for Heart Failure

1 location in Detroit

Sponsor: David Lanfear

Sex: All·Age: 18 - 89

Code: NCT07054489·Recruiting·Listed Jul 2025

Apply to this trial

The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

Sites in Detroit +6 more locations

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting·Listed Apr 2021

Apply to this trial

Safety and Efficacy of Epcoritamab With Gemcitabine, Dexamethasone, and Cisplatin (GDP) Salvage Chemotherapy in Relapsed Refractory Large B-cell Lymphoma

for Large Cell Lymphoma, Diffuse

Drug: Epcoritamab

Sites in Detroit +3 more locations

Sponsor: Dipenkumar Modi

Sex: All·Age: 18+

Code: NCT05852717·Phase 2·Recruiting·Listed May 2023

Apply to this trial

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

for Colorectal Cancer Stage II

Sites in Detroit, Warren +373 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07018869·Phase 3·Recruiting·Listed Jun 2025

Apply to this trial

Efficacy of Ketorolac for Postoperative Pain Management in Hip Arthroscopy

for Femoracetabular Impingement

1 location in Detroit

Sponsor: Henry Ford Health System

Sex: All·Age: 18 - 89

Code: NCT07037888·Phase 4·Recruiting·Listed Jun 2025

Apply to this trial

ONC201 Plus Weekly Paclitaxel in Patients With Platinum Refractory or Resistant Ovarian Cancer

for Malignant Ovarian Epithelial Tumor

Sites in Detroit & Flint

Sponsor: Ira Winer

Sex: Female·Age: 18+

Code: NCT04055649·Phase 2·Recruiting·Listed Aug 2019

Apply to this trial

International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

Sites in Detroit +34 more locations

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting·Listed May 2017

Apply to this trial

Project 4: ACHIEVE PATHFINDER

for Heart Failure

1 location in Detroit

Sponsor: Henry Ford Health System

Sex: All·Age: 18+

Code: NCT06070428·Recruiting·Listed Oct 2023

Apply to this trial

Treatment of Sleep Apnea in Patients With Cervical Spinal Cord Injury

for Sleep Apnea

1 location in Detroit

Sponsor: John D. Dingell VA Medical Center

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT02922894·Phase 4·Recruiting·Listed Oct 2016

Apply to this trial

Sleep Disordered Breathing With Opioid Use

for Sleep Apnea

1 location in Detroit

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT05589753·Phase 1, Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

for Arrythmia

Sites in Detroit +18 more locations

Sponsor: University of Rochester

Sex: All·Age: 18+

Code: NCT05034432·Phase 4·Recruiting·Listed Sep 2021

Apply to this trial

DapagliFLOzin in Renal AL Amyloidosis (FLORAL)

for Renal AL Amyloidosis

Drug: Dapagliflozin

1 location in Detroit

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All·Age: 18+

Code: NCT06420167·Phase 2·Recruiting·Listed May 2024

Apply to this trial

Dietary Reporting In The Amyloidoses

for Amyloidosis

1 location in Detroit

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All·Age: 18+

Code: NCT05738005·Recruiting·Listed Feb 2023

Apply to this trial

Iberdomide and Daratumumab as Maintenance Therapy After an Autologous Stem Cell Transplant for Multiple Myeloma

for Multiple Myeloma

Drug: Daratumumab

Sites in Detroit & Lansing

Sponsor: Barbara Ann Karmanos Cancer Institute

Sex: All·Age: 18+

Code: NCT06107738·Phase 2·Recruiting·Listed Oct 2023

Apply to this trial

The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery

for Anesthesia

Sites in Detroit, Ann Arbor +7 more locations

Sponsor: University of California, San Francisco

Sex: All·Age: 18+

Code: NCT06802224·Phase 4·Recruiting·Listed Jan 2025

Apply to this trial

A Comparison of Radical Prostatectomy and Precision Prostatectomy in Low- and Intermediate-risk Prostate Cancers.

for Prostatectomy

1 location in Detroit

Sponsor: Henry Ford Health System

Sex: Male·Age: All ages

Code: NCT07348367·Recruiting·Listed Jan 2026

Apply to this trial

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Detroit, Warren +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

ALS/MND Natural History Study Data Repository

for ALS

Sites in Detroit, Grand Rapids +12 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT05966038·Recruiting·Listed Jul 2023

Apply to this trial