Oncology Clinical Trials in Duarte, CA

As of September 2026, 276 paid clinical trials are recruiting for Oncology in Duarte, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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280 clinical trials for Oncology

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cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

for Brain Cancer

Sites in Duarte +15 more locations

Sponsor: Adela, Inc

Sex: All·Age: 40+·Accepts healthy volunteers

Code: NCT05366881·Recruiting·Listed May 2022

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A Study of BH-30236 in Relapsed/ Refractory Acute Myelogenous Leukemia and Higher Risk Myelodysplastic Syndrome

for Leukemia

Sites in Duarte, Los Angeles +11 more locations

Sponsor: BlossomHill Therapeutics

Sex: All·Age: 18+

Code: NCT06501196·Phase 1·Recruiting·Listed Jul 2024

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Cevostamab in Combination With Pomalidomide and Dexamethasone Versus Standard of Care in Participants With Previously Treated Multiple Myeloma

for Multiple Myeloma

Sites in Duarte, Irvine +5 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT07555938·Phase 3·Recruiting·Listed Apr 2026

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A Phase 1 Study Evaluating DISP-10 in Participants With Advanced Gastrointestinal Cancers

for Colorectal Cancer

Sites in Duarte, Newport Beach +3 more locations

Sponsor: Dispatch Biotherapeutics

Sex: All·Age: 18+

Code: NCT07544589·Phase 1·Recruiting·Listed Apr 2026

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Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung

for Lung Cancer

Sites in Duarte, Newport Beach +6 more locations

Sponsor: Vergent Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT07499674·Phase 3·Recruiting·Listed Mar 2026

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Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Duarte, Irvine +2 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07476287·Phase 2·Recruiting·Listed Mar 2026

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A Study to Evaluate Adverse Events, Change in Disease Activity, Tolerability, and How Intravenous ABBV-438 Moves Through the Body in Adult Participants With Multiple Myeloma (MM)

for Multiple Myeloma

Drug: ABBV-438

Sites in Duarte, Irvine +4 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT07409246·Phase 1·Recruiting·Listed Feb 2026

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A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

for Colorectal Cancer

Sites in Duarte, Los Angeles +8 more locations

Sponsor: Cartography Biosciences

Sex: All·Age: 18+

Code: NCT07321106·Phase 1·Recruiting·Listed Jan 2026

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Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2)

for Solid Tumor

Drug: Givastomig

Sites in Duarte +2 more locations

Sponsor: I-Mab Biopharma US Limited

Sex: All·Age: 18+

Code: NCT07432295·Phase 2·Recruiting·Listed Feb 2026

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A Study to Learn About the Study Medicine Called PF-08032562 in People With Advanced or Metastatic Solid Tumors

for Advanced Breast Cancer

Sites in Duarte +12 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07318805·Phase 1·Recruiting·Listed Jan 2026

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A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

for Chronic Lymphocytic Leukemia

Drug: Sonrotoclax

Sites in Duarte, Orange +11 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07277231·Phase 3·Recruiting·Listed Dec 2025

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A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis

for Secondary AML

Sites in Duarte, San Diego & Sacramento

Sponsor: Aspera Biomedicines, Inc.

Sex: All·Age: 18+

Code: NCT07250646·Phase 1·Recruiting·Listed Nov 2025

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A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

Sites in Duarte, La Jolla +6 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting·Listed Sep 2025

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A Study to Evaluate the Safety, Pharmacokinetics, and Anti-Tumor Activity of VVD-133214 as Monotherapy and in Combination in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Duarte, Los Angeles +13 more locations

Sponsor: Vividion Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06004245·Phase 1·Recruiting·Listed Aug 2023

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Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19)

for B-cell Acute Lymphoblastic Leukemia

Sites in Duarte, Los Angeles +9 more locations

Sponsor: Vironexis Biotherapeutics Inc.

Sex: All·Age: 13 - 90

Code: NCT06533579·Phase 1, Phase 2·Recruiting·Listed Aug 2024

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A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

for Advanced Solid Tumors

Sites in Duarte, Newport Beach +4 more locations

Sponsor: SEED Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07197554·Phase 1·Recruiting·Listed Sep 2025

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A Study to Assess the Safety, Tolerability, and Antileukemic Activity of Debio 1562M in Participants With Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Sites in Duarte +6 more locations

Sponsor: Debiopharm International SA

Sex: All·Age: 18+

Code: NCT06969430·Phase 1, Phase 2·Recruiting·Listed May 2025

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A Study of BG-C477 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Duarte +8 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06596473·Phase 1·Recruiting·Listed Sep 2024

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A Study of Elritercept to Treat Anemia in Adults With Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)

for Myelodysplastic Syndromes

Sites in Duarte +8 more locations

Sponsor: Takeda

Sex: All·Age: 18+

Code: NCT04419649·Phase 2·Recruiting·Listed Jun 2020

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A First-in-human Study to Learn About the Safety of BAY 3547926 and How Well it Works in Participants With Advanced Liver Cancer

for Hepatocellular Carcinoma

Sites in Duarte +1 more location

Sponsor: Bayer

Sex: All·Age: 18+

Code: NCT06764316·Phase 1·Recruiting·Listed Jan 2025

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A Study to Assess Change in Disease Activity and Adverse Events (AE)s in Adult Participants With Multiple Myeloma Receiving T Cell Engaging Bi/Tri-specific Antibodies Intravenously (IV)/Subcutaneously (SC) Alone or in Combinations

for Multiple Myeloma

Sites in Duarte, Irvine +12 more locations

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06892522·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

for Hepatocellular Carcinoma

Sites in Duarte +4 more locations

Sponsor: Eureka Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT04864054·Phase 1, Phase 2·Recruiting·Listed Apr 2021

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First-In-Human Study of STX-721/PFL-721 in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Harboring EGFR or HER2 Exon 20 Insertion Mutations

for Non-Small Cell Lung Cancer

Sites in Duarte, Huntington Beach +7 more locations

Sponsor: Pierre Fabre Medicament

Sex: All·Age: 18+

Code: NCT06043817·Phase 1, Phase 2·Recruiting·Listed Sep 2023

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LYL273 for Patients With Relapsed or Refractory mCRC

for Colorectal Cancer

Sites in Duarte, San Francisco +2 more locations

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05319314·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Duarte, Los Angeles +7 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05981703·Phase 1·Recruiting·Listed Aug 2023

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Study With [225Ac]Ac-FL-020 in mCRPC Participants

for Metastatic Castration-resistant Prostate Cancer

Sites in Duarte, Irvine +3 more locations

Sponsor: Full-Life Technologies UK Limited

Sex: Male·Age: 18+

Code: NCT06492122·Phase 1·Recruiting·Listed Jul 2024

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Preliminary Clinical Activity of RO7673396 in Participants With Advanced Solid Tumors Harboring Rat Sarcoma Viral Oncogene Homolog (RAS) Mutation(s)

for Neoplasms

Sites in Duarte +5 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT06884618·Phase 1·Recruiting·Listed Mar 2025

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A Study of Carmustine With and Without Ethanol in Subjects With Lymphoma

for Lymphoma

Sites in Duarte +3 more locations

Sponsor: VIVUS LLC

Sex: All·Age: 18+

Code: NCT06915246·Phase 2·Recruiting·Listed Apr 2025

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Safety and Immunogenicity of Innocell Autologous Cellular Immunotherapy for Recurrent Epithelial Ovarian Cancer

for Ovarian Cancer

1 location in Duarte

Sponsor: PhotonPharma, Inc.

Sex: Female·Age: 18+

Code: NCT06366490·Phase 1·Recruiting·Listed Apr 2024

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A Study of Selinexor Monotherapy in Subjects With JAK Inhibitor-naïve Myelofibrosis and Moderate Thrombocytopenia

for Myelofibrosis

Drug: Selinexor

Sites in Duarte +6 more locations

Sponsor: Karyopharm Therapeutics Inc

Sex: All·Age: 18+

Code: NCT05980806·Phase 2·Recruiting·Listed Aug 2023

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A Study of KK2269 in Adult Participants With Solid Tumors

for Advanced Solid Tumor

Sites in Duarte, Newport Beach +5 more locations

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18+

Code: NCT06266299·Phase 1·Recruiting·Listed Feb 2024

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BI-1808 as a Single Agent and With Pembrolizumab (KEYTRUDA® ) in Treatment of Advanced Malignancies(Keynote-D20)

for Advanced Malignancies

Sites in Duarte +2 more locations

Sponsor: BioInvent International AB

Sex: All·Age: 18+

Code: NCT04752826·Phase 1, Phase 2·Recruiting·Listed Feb 2021

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A Dose Randomization Study of Bulumtatug Fuvedotin in TNBC Patients Previously Treated With ADCs

for Triple Negative Breast Cancer

Sites in Duarte, La Jolla +4 more locations

Sponsor: Mabwell (Shanghai) Bioscience Co., Ltd.

Sex: All·Age: 18+

Code: NCT06908928·Phase 1·Recruiting·Listed Apr 2025

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Safety and Preliminary Efficacy of MT-601 in Patients With Relapsed/Refractory Lymphoma

for Non-Hodgkin Lymphoma, Adult

Sites in Duarte +6 more locations

Sponsor: Marker Therapeutics, Inc.

Sex: All·Age: 18 - 100

Code: NCT05798897·Phase 1·Recruiting·Listed Apr 2023

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A Long Term Follow-up Study of TScan TCR-T Products

for AML

Sites in Duarte +1 more location

Sponsor: TScan Therapeutics, Inc.

Sex: All·Age: 18 - 110

Code: NCT06976736·Recruiting·Listed May 2025

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Daily Adaptive Radiation Therapy Using an Individualized Approach for Prostate Cancer

for Prostate Cancer

Sites in Duarte, Irvine +1 more location

Sponsor: Varian, a Siemens Healthineers Company

Sex: Male·Age: 18+

Code: NCT05804318·Recruiting·Listed Apr 2023

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A Study of GLB-001 in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Relapsed or Refractory Higher Risk Myelodysplastic Syndromes

for Acute Myeloid Leukemia

Sites in Duarte +2 more locations

Sponsor: GluBio Therapeutics Inc.

Sex: All·Age: 18+

Code: NCT06146257·Phase 1·Recruiting·Listed Nov 2023

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CBM588 Capsules in Combination With Nivolumab and Ipilimumab for the Treatment of Advanced Stage Kidney Cancer

for Advanced Clear Cell Renal Cell Carcinoma

Drug: Ipilimumab

1 location in Duarte

Sponsor: Osel, Inc.

Sex: All·Age: 18+

Code: NCT06399419·Phase 1·Recruiting·Listed May 2024

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Prospective Data Registry and Quality of Life Assessment of Patients Undergoing Radiotherapy With the RefleXion Medical Radiotherapy System

for Cancer

Sites in Duarte, Palo Alto +3 more locations

Sponsor: RefleXion Medical

Sex: All·Age: All ages

Code: NCT05406167·Recruiting·Listed Jun 2022

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This is a Study to Evaluate the Safety and Tolerability of ABL503, and to Determine the Maximum Tolerated Dose (MTD) and Recommended Phase 2 Dose (RP2D) of ABL503 in Subjects with Any Progressive Locally Advanced or Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Duarte, Los Angeles +3 more locations

Sponsor: ABL Bio, Inc.

Sex: All·Age: 18+

Code: NCT04762641·Phase 1·Recruiting·Listed Feb 2021

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Conditions in Oncology (Duarte, CA)

Solid tumor· 50 Acute myeloid leukemia (AML)· 30 Non-small cell lung cancer (NSCLC)· 29 Breast cancer· 26 Hematologic malignancy· 26 Myelodysplastic syndromes (MDS)· 25 Colorectal cancer· 19 Prostate cancer· 18 Ovarian cancer· 17 Pancreatic cancer· 15 Multiple myeloma· 14 Non-Hodgkin lymphoma· 14 Cancer (any)· 14 Metastatic breast cancer· 13 Gastric cancer· 13 Esophageal cancer· 13 Head and neck cancer· 13 Endometrial cancer· 11 Acute lymphoblastic leukemia· 11 Bladder cancer· 10 Diffuse large B-cell lymphoma (DLBCL)· 10 Chronic lymphocytic leukemia (CLL)· 9 Leukemia (other)· 9 Lung cancer· 8 Kidney cancer· 8 Myelofibrosis· 8 Mantle cell lymphoma· 8 Melanoma· 8 Cervical cancer· 7 Hodgkin lymphoma· 7 Gastroesophageal junction cancer· 6 Liver cancer· 6 Biliary tract cancer· 6 Triple-negative breast cancer· 5 Metastatic prostate cancer· 5 Glioblastoma· 5 Myeloproliferative neoplasm· 5 Marginal zone lymphoma· 5 Small lymphocytic lymphoma· 5 Follicular lymphoma· 4 Sarcoma· 4 Small cell lung cancer· 3 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Neuroendocrine tumors· 3 Chronic myelomonocytic leukemia· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Rhabdomyosarcoma· 1 Neuroblastoma· 1