Oncology Clinical Trials in Duarte, CA

As of September 2026, 276 paid clinical trials are recruiting for Oncology in Duarte, California. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 1, 2026.

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280 clinical trials for Oncology

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Positron Emission Tomography (PET) Guided Stereotactic Body Radiation Therapy for the Treatment of Oligoprogressive Non-small Cell Lung Cancer, Melanoma, and Renal Cell Carcinoma

for Lung Non-Small Cell Carcinoma

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05830058·Phase 2·Recruiting·Listed Apr 2023

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PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric Cancer

for Clinical Stage IV Gastric Cancer AJCC v8

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT04329494·Phase 1·Recruiting·Listed Apr 2020

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Actinium 225 Labeled Anti-CEA Antibody (Ac225-DOTA-M5A) for the Treatment of CEA Producing Advanced or Metastatic Cancers

for Advanced Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05204147·Phase 1·Recruiting·Listed Jan 2022

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8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05263284·Phase 1·Recruiting·Listed Mar 2022

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Spatiotemporal Stereotactic Body Radiation Therapy for the Treatment of Patients With Polymetastatic Solid Tumors

for Metastatic Malignant Solid Neoplasm

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05733949·EARLY_Phase 1·Recruiting·Listed Feb 2023

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

Sites in Duarte +6 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting·Listed Oct 2021

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Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

for Prostate Adenocarcinoma

Sites in Duarte, Los Angeles +1 more location

Sponsor: Stephen Freedland

Sex: Male·Age: All ages

Code: NCT05832086·Phase 2·Recruiting·Listed Apr 2023

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Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

for Hodgkin Lymphoma

Sites in Duarte, Stanford +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT03618550·Phase 2·Recruiting·Listed Aug 2018

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Childhood Cancer Survivor Study

for Cancer

Sites in Duarte, Orange +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Biologically Guided Radiation Therapy (BgRT) and Stereotactic Body Radiation Therapy (SBRT) to Tyrosine Kinase Inhibitor in Oligoprogressive Oncogenic Positive Non-Small Cell Lung Carcinoma

for Lung Non-Small Cell Carcinoma

Sites in Duarte +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06014827·Phase 2·Recruiting·Listed Aug 2023

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Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte +2 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2·Recruiting·Listed Feb 2025

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 70

Code: NCT06287944·Phase 1·Recruiting·Listed Mar 2024

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AOH1996 for the Treatment of Refractory Solid Tumors

for Refractory Malignant Solid Neoplasm

Sites in Duarte, Long Beach +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05227326·Phase 1·Recruiting·Listed Feb 2022

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Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

for Hematopoietic and Lymphatic System Neoplasm

Drug: Ruxolitinib

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07025538·Phase 1·Recruiting·Listed Jun 2025

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Glofitamab With Obinutuzumab, Venetoclax, and Lenalidomide for the Treatment of Patients With Newly Diagnosed High Risk Mantle Cell Lymphoma

for Blastoid Variant Mantle Cell Lymphoma

Drug: Glofitamab

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT05861050·Phase 1, Phase 2·Recruiting·Listed May 2023

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L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte, Huntington Beach & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07220447·EARLY_Phase 1·Recruiting·Listed Oct 2025

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Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06498973·Phase 1·Recruiting·Listed Jul 2024

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Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Mosunetuzumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672251·Phase 2·Recruiting·Listed Jan 2023

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Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for Acute Graft Versus Host Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05443425·Phase 1·Recruiting·Listed Jul 2022

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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for Lung Non-Small Cell Carcinoma

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06139627·Recruiting·Listed Nov 2023

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Early Onset Colorectal Cancer Detection

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06342401·Recruiting·Listed Apr 2024

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An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for Hepatocellular Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06342414·Recruiting·Listed Apr 2024

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

Sites in Duarte +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting·Listed Jul 2023

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in Duarte, South Pasadena +36 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06996119·Phase 1·Recruiting·Listed May 2025

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Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Riverside & La Jolla

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT06763328·Phase 3·Recruiting·Listed Jan 2025

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Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06500377·Recruiting·Listed Jul 2024

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An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05376878·Phase 4·Recruiting·Listed May 2022

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Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT06815003·Phase 2·Recruiting·Listed Feb 2025

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Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for Recurrent Astrocytoma, IDH-Mutant, Grade 3

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06815029·Phase 1·Recruiting·Listed Feb 2025

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IVIG for Infection Prevention After CAR-T-Cell Therapy

for Hematologic Malignancies

Sites in Duarte +6 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05952804·Phase 2·Recruiting·Listed Jul 2023

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Duarte, Los Angeles +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Duarte, Stanford +7 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

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Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Cemiplimab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06860815·Phase 2·Recruiting·Listed Mar 2025

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A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

for Multiple Myeloma

Sites in Duarte, West Covina +9 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07225738·Recruiting·Listed Nov 2025

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

Sites in Duarte +8 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting·Listed Dec 2021

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Venetoclax and Obinutuzumab Followed by Epcoritamab for the Treatment of Untreated Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, LonGEVity Trial

for Chronic Lymphocytic Leukemia

Drug: Epcoritamab

Sites in Duarte, Long Beach +5 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07218510·Phase 2·Recruiting·Listed Oct 2025

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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for Prostate Carcinoma

Sites in Duarte, San Francisco +5 more locations

Sponsor: University of Washington

Sex: Male·Age: 40+·Accepts healthy volunteers

Code: NCT04472338·Recruiting·Listed Jul 2020

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Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for Recurrent B-Cell Non-Hodgkin Lymphoma

Drug: Nivolumab

Sites in Duarte, Sacramento +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05272384·Phase 1·Recruiting·Listed Mar 2022

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

Sites in Duarte, Burbank +130 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting·Listed Apr 2023

Apply to this trial

Conditions in Oncology (Duarte, CA)

Solid tumor· 50 Acute myeloid leukemia (AML)· 30 Non-small cell lung cancer (NSCLC)· 29 Breast cancer· 26 Hematologic malignancy· 26 Myelodysplastic syndromes (MDS)· 25 Colorectal cancer· 19 Prostate cancer· 18 Ovarian cancer· 17 Pancreatic cancer· 15 Multiple myeloma· 14 Non-Hodgkin lymphoma· 14 Cancer (any)· 14 Metastatic breast cancer· 13 Gastric cancer· 13 Esophageal cancer· 13 Head and neck cancer· 13 Endometrial cancer· 11 Acute lymphoblastic leukemia· 11 Bladder cancer· 10 Diffuse large B-cell lymphoma (DLBCL)· 10 Chronic lymphocytic leukemia (CLL)· 9 Leukemia (other)· 9 Lung cancer· 8 Kidney cancer· 8 Myelofibrosis· 8 Mantle cell lymphoma· 8 Melanoma· 8 Cervical cancer· 7 Hodgkin lymphoma· 7 Gastroesophageal junction cancer· 6 Liver cancer· 6 Biliary tract cancer· 6 Triple-negative breast cancer· 5 Metastatic prostate cancer· 5 Glioblastoma· 5 Myeloproliferative neoplasm· 5 Marginal zone lymphoma· 5 Small lymphocytic lymphoma· 5 Follicular lymphoma· 4 Sarcoma· 4 Small cell lung cancer· 3 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Neuroendocrine tumors· 3 Chronic myelomonocytic leukemia· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Rhabdomyosarcoma· 1 Neuroblastoma· 1