Oncology Clinical Trials in Duarte, CA

As of July 2026, 263 paid clinical trials are recruiting for Oncology in Duarte, California. Oncology trials evaluate immunotherapies, targeted therapies, antibody-drug conjugates, and combination regimens across solid tumors and blood cancers — from early-phase first-in-human studies to phase 3 registration trials. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

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267 clinical trials for Oncology

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Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06498973·Phase 1·Recruiting·Listed Jul 2024

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Phase II Study of Second- Line Pembrolizumab Plus GVD for Relapsed or Refractory Hodgkin Lymphoma

for Hodgkin Lymphoma

Sites in Duarte, Stanford +8 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT03618550·Phase 2·Recruiting·Listed Aug 2018

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

Sites in Duarte +6 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting·Listed Oct 2021

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Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Mosunetuzumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672251·Phase 2·Recruiting·Listed Jan 2023

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Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for Acute Graft Versus Host Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05443425·Phase 1·Recruiting·Listed Jul 2022

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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for Lung Non-Small Cell Carcinoma

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06139627·Recruiting·Listed Nov 2023

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Early Onset Colorectal Cancer Detection

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06342401·Recruiting·Listed Apr 2024

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An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for Hepatocellular Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06342414·Recruiting·Listed Apr 2024

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

Sites in Duarte +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting·Listed Jul 2023

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Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT06815003·Phase 2·Recruiting·Listed Feb 2025

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Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for Recurrent Astrocytoma, IDH-Mutant, Grade 3

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06815029·Phase 1·Recruiting·Listed Feb 2025

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Pancreatic Cancer Early Detection Consortium

for Pancreas Cancer

Sites in Duarte, Burbank +41 more locations

Sponsor: Arbor Research Collaborative for Health

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT04970056·Recruiting·Listed Jul 2021

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Comparing the Impact of Four Types of Meditation Practices for Relaxation in Cancer Survivors

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06500377·Recruiting·Listed Jul 2024

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An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05376878·Phase 4·Recruiting·Listed May 2022

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IVIG for Infection Prevention After CAR-T-Cell Therapy

for Hematologic Malignancies

Sites in Duarte +6 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05952804·Phase 2·Recruiting·Listed Jul 2023

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8-Chloroadenosine in Combination With Venetoclax for the Treatment of Patients With Relapsed/Refractory Acute Myeloid Leukemia

for Acute Myeloid Leukemia

Drug: Venetoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05263284·Phase 1·Recruiting·Listed Mar 2022

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Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte +2 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2·Recruiting·Listed Feb 2025

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Duarte, Stanford +7 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

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Triptorelin for the Prevention of Ovarian Damage in Adolescents and Young Adults With Cancer

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte, Orange +178 more locations

Sponsor: Children's Oncology Group

Sex: Female·Age: Up to 39

Code: NCT06513962·Phase 3·Recruiting·Listed Jul 2024

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Clinical Trial of Approaches to Prostate Cancer Surgery

for Prostate Cancer

Sites in Duarte +8 more locations

Sponsor: Weill Medical College of Cornell University

Sex: Male·Age: 40 - 80

Code: NCT05155501·Recruiting·Listed Dec 2021

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Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer

for Anatomic Stage IV Breast Cancer AJCC v8

Drug: Cemiplimab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06860815·Phase 2·Recruiting·Listed Mar 2025

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Enasidenib (AG-221) Maintenance Post Allogeneic HCT in Patients With IDH2 Mutation

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03728335·Phase 2·Recruiting·Listed Nov 2018

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Association Between Exercise, Patient-Reported Outcomes, and Clinical Events in Adult Cancer Survivors

for Survivorship

Sites in Duarte, Los Angeles +2 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07030686·Recruiting·Listed Jun 2025

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06287944·Phase 1·Recruiting·Listed Mar 2024

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Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

for Prostate Carcinoma

Sites in Duarte, San Francisco +5 more locations

Sponsor: University of Washington

Sex: Male·Age: 40+·Accepts healthy volunteers

Code: NCT04472338·Recruiting·Listed Jul 2020

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Testing the Combination of Nivolumab and ASTX727 for Relapsed or Refractory B-Cell Lymphoma

for Recurrent B-Cell Non-Hodgkin Lymphoma

Drug: Nivolumab

Sites in Duarte, Sacramento +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05272384·Phase 1·Recruiting·Listed Mar 2022

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Intermittent Fasting Using a Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

for Prostate Adenocarcinoma

Sites in Duarte, Los Angeles +1 more location

Sponsor: Stephen Freedland

Sex: Male·Age: All ages

Code: NCT05832086·Phase 2·Recruiting·Listed Apr 2023

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Metabolic Interventions (Time-Restricted Eating, GLP1 Receptor Agonist, and Heart Healthy Diet) to Improve Cardiometabolic Health in Prostate Cancer Patients During Androgen Deprivation Therapy, IMPACT-ADT Trial

for Prostate Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 30 - 79

Code: NCT07202247·Phase 2·Recruiting·Listed Oct 2025

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Abemaciclib and Endocrine Therapy in Older Patients With Breast Cancer.

for Anatomic Stage IV Breast Cancer AJCC v8

Sites in Duarte, South Pasadena +4 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 70+

Code: NCT04305834·Phase 2·Recruiting·Listed Mar 2020

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Phase II Non-Randomized Study Evaluating POSLUMA-PSMA PET Response After Oligo- Metastatic/Progressive-directed Treatment With Radiotherapy (PROMPT-R)

for Prostate Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: Male·Age: 18+

Code: NCT07210086·Phase 2·Recruiting·Listed Oct 2025

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Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

for End of Life

Sites in Duarte, Fullerton +10 more locations

Sponsor: Stanford University

Sex: All·Age: 18+

Code: NCT05297734·Recruiting·Listed Mar 2022

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Orca-T Following Chemotherapy and Total Marrow and Lymphoid Irradiation for the Treatment of Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia or Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06195891·Phase 1·Recruiting·Listed Jan 2024

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Allogeneic CMV-Specific CD19-CAR T Cells Plus CMV-MVA Triplex Vaccine After Matched Related Donor Hematopoietic Cell Transplant for the Treatment of Patients With High-Risk Acute Lymphoblastic Leukemia

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06735690·EARLY_Phase 1·Recruiting·Listed Dec 2024

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Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

for Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Drug: Sonrotoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06859008·Phase 1·Recruiting·Listed Mar 2025

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Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

for Mantle Cell Lymphoma

Drug: Venetoclax

Sites in Duarte +3 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03523975·Phase 1, Phase 2·Recruiting·Listed May 2018

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte, Downey +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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A Platform Protocol to Investigate Post-Transplant Cyclophosphamide-Based Graft-Versus-Host Disease Prophylaxis in Patients With Hematologic Malignancies Undergoing Mismatched Unrelated Donor Peripheral Blood Stem Cell Transplantation

for AML (Acute Myelogenous Leukemia)

Sites in Duarte, Palo Alto +11 more locations

Sponsor: Center for International Blood and Marrow Transplant Research

Sex: All·Age: 18 - 66

Code: NCT06859424·Phase 2·Recruiting·Listed Mar 2025

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Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

for Prostate Adenocarcinoma

Sites in Duarte, Burbank +130 more locations

Sponsor: SWOG Cancer Research Network

Sex: Male·Age: 18+

Code: NCT05806515·Phase 2·Recruiting·Listed Apr 2023

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Digital Health Intervention for Self-Management and Telemonitoring in Chimeric Antigen Receptor (CAR-T) Therapy

for Hematologic Malignancies

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07186192·Phase 3·Recruiting·Listed Sep 2025

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Mezigdomide (CC-92480) Post Idecabtagene Vicleucel in Treating Patients With Relapsed Multiple Myeloma

for Multiple Myeloma

Drug: Mezigdomide

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06048250·Phase 1·Recruiting·Listed Sep 2023

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Conditions in Oncology (Duarte, CA)

Solid tumor· 45 Acute myeloid leukemia (AML)· 30 Non-small cell lung cancer (NSCLC)· 27 Myelodysplastic syndromes (MDS)· 25 Hematologic malignancy· 23 Breast cancer· 22 Prostate cancer· 19 Colorectal cancer· 17 Pancreatic cancer· 15 Ovarian cancer· 15 Esophageal cancer· 14 Non-Hodgkin lymphoma· 14 Cancer (any)· 14 Metastatic breast cancer· 13 Multiple myeloma· 13 Gastric cancer· 12 Acute lymphoblastic leukemia· 11 Head and neck cancer· 11 Endometrial cancer· 10 Leukemia (other)· 10 Diffuse large B-cell lymphoma (DLBCL)· 10 Bladder cancer· 9 Myelofibrosis· 9 Lung cancer· 8 Gastroesophageal junction cancer· 7 Kidney cancer· 7 Chronic lymphocytic leukemia (CLL)· 7 Hodgkin lymphoma· 7 Mantle cell lymphoma· 7 Melanoma· 7 Liver cancer· 6 Biliary tract cancer· 6 Cervical cancer· 6 Triple-negative breast cancer· 5 Myeloproliferative neoplasm· 5 Small lymphocytic lymphoma· 5 Metastatic prostate cancer· 4 Follicular lymphoma· 4 Marginal zone lymphoma· 4 Sarcoma· 4 Metastatic colorectal cancer· 3 Colon cancer· 3 Fallopian tube cancer· 3 Glioblastoma· 3 Neuroendocrine tumors· 3 Small cell lung cancer· 2 Chronic myelomonocytic leukemia· 2 Thyroid cancer· 2 Osteosarcoma· 2 Ewing sarcoma· 2 HER2-positive breast cancer· 1 HER2-negative breast cancer· 1 Brain cancer· 1 Brain metastases· 1 Burkitt lymphoma· 1 Neuroblastoma· 1