Paid Clinical Trials in Duarte, CA

As of September 2026, 546 paid clinical trials are recruiting in Duarte, California. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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508 clinical trials

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Enfortumab Vedotin Plus Pembrolizumab With Selective Bladder Sparing for Treatment of Muscle-invasive Bladder Cancer

for Muscle Invasive Bladder Urothelial Carcinoma

Sites in Duarte +4 more locations

Sponsor: Matthew Galsky

Sex: All·Age: 18+

Code: NCT06809140·Phase 2·Recruiting·Listed Feb 2025

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Pacritinib in Combination With a BTK Inhibitor for the Treatment of Patients With Relapsed or Refractory Mantle Cell Lymphoma

for Recurrent Mantle Cell Lymphoma

Drug: Pacritinib

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06675123·Phase 1·Recruiting·Listed Nov 2024

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Immunotherapy (Nivolumab and Ipilimumab) With and Without a Live Biotherapeutic Product (EXL01) for the Treatment of Metastatic Renal Cell Cancer

for Advanced Clear Cell Renal Cell Carcinoma

Drug: Ipilimumab

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07128680·Phase 1·Recruiting·Listed Aug 2025

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Recombinant Erwinia Asparaginase and Venetoclax in Combination With Blinatumomab for the Treatment of Relapsed or Refractory CD19 Positive B-cell Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

Drug: Venetoclax

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 12 - 55

Code: NCT07133997·Phase 1·Recruiting·Listed Aug 2025

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Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte +2 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT06817889·Phase 2·Recruiting·Listed Feb 2025

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SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal Cancer

for Oropharyngeal Cancer

Sites in Duarte, Corona +21 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT05451004·Phase 3·Recruiting·Listed Jul 2022

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Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma

for AIDS-Related Diffuse Large B-cell Lymphoma

Sites in Duarte +6 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT05077527·Phase 1·Recruiting·Listed Oct 2021

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225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome

for Acute Lymphoblastic Leukemia

Drug: Daratumumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 70

Code: NCT06287944·Phase 1·Recruiting·Listed Mar 2024

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Durvalumab With or Without Lenalidomide in Treating Patients With Relapsed or Refractory Cutaneous or Peripheral T Cell Lymphoma

for Folliculotropic Mycosis Fungoides

Drug: Durvalumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT03011814·Phase 1, Phase 2·Recruiting·Listed Jan 2017

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AOH1996 for the Treatment of Refractory Solid Tumors

for Refractory Malignant Solid Neoplasm

Sites in Duarte, Long Beach +1 more location

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05227326·Phase 1·Recruiting·Listed Feb 2022

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Childhood Cancer Survivor Study

for Cancer

Sites in Duarte, Orange +25 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT01120353·Recruiting·Listed May 2010

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Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE Trial

for Locally Advanced Rectal Adenocarcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06834126·Phase 1·Recruiting·Listed Feb 2025

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Immunotherapy Biomarkers to Predict First-line PD(L)1-based Immunotherapy Response and Selection of Second-line Treatment in Stage IIIB-IV Non-small Cell Lung Cancer, IMMUNO-BIOMAP Trial

for Lung Non-Small Cell Carcinoma

Sites in Duarte, South Pasadena +11 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07288034·Phase 2·Recruiting·Listed Dec 2025

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Fisetin to Improve Physical Function in Stage I-III Breast Cancer Survivors

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Pasadena +5 more locations

Sponsor: Jonsson Comprehensive Cancer Center

Sex: Female·Age: All ages

Code: NCT05595499·Phase 2·Recruiting·Listed Oct 2022

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Tagraxofusp and Azacitidine for Maintenance Treatment in Patients With CD123 Positive AML and MDS Following Donor Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06498973·Phase 1·Recruiting·Listed Jul 2024

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Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells

for Metastatic Prostate Adenocarcinoma With Neuroendocrine Differentiation

Sites in Duarte, Los Angeles +9 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Male·Age: 18+

Code: NCT05691465·Phase 2·Recruiting·Listed Jan 2023

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Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma

for Recurrent Diffuse Large B-Cell Lymphoma

Drug: Mosunetuzumab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05672251·Phase 2·Recruiting·Listed Jan 2023

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Leflunomide in Combination With Steroids for the Treatment of Acute Graft-versus-Host Disease After Donor Stem Cell Transplant for Hematologic Malignancies

for Acute Graft Versus Host Disease

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05443425·Phase 1·Recruiting·Listed Jul 2022

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Evaluation of Geriatric Assessment and Management for Older Adults With Non-small Cell Lung Cancer Receiving Chemotherapy Radiation Therapy

for Lung Non-Small Cell Carcinoma

Sites in Duarte +2 more locations

Sponsor: City of Hope Medical Center

Sex: All·Age: 60+·Accepts healthy volunteers

Code: NCT06139627·Recruiting·Listed Nov 2023

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Acolbifene Versus Low Dose Tamoxifen for the Prevention of Breast Cancer in Premenopausal Women at High Risk for Development of Breast Cancer

for Breast Atypical Hyperplasia

Sites in Duarte +3 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 35+

Code: NCT05941520·Phase 2·Recruiting·Listed Jul 2023

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Early Onset Colorectal Cancer Detection

for Colorectal Cancer

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06342401·Recruiting·Listed Apr 2024

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An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

for Hepatocellular Carcinoma

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06342414·Recruiting·Listed Apr 2024

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

Sites in Duarte, Palo Alto +20 more locations

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting·Listed May 2023

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in Duarte, South Pasadena +36 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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Metformin for the Treatment of Insulin Resistance in Women With Stage I-III Breast Cancer Completing Chemotherapy

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Riverside & La Jolla

Sponsor: City of Hope Medical Center

Sex: Female·Age: 18+

Code: NCT06763328·Phase 3·Recruiting·Listed Jan 2025

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Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant

for Acute Myeloid Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 75

Code: NCT06996119·Phase 1·Recruiting·Listed May 2025

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An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis

for Anatomic Stage IV Breast Cancer AJCC v8

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT05376878·Phase 4·Recruiting·Listed May 2022

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Testing the Combination of Anti-cancer Drugs Mosunetuzumab, Polatuzumab Vedotin, and Lenalidomide for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma

for Diffuse Large B-Cell Lymphoma, Not Otherwise Specified

Drug: Polatuzumab Vedotin

Sites in Duarte, Sacramento +6 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06015880·Phase 1·Recruiting·Listed Aug 2023

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Papaverine in Combination With Chemoradiation for the Treatment of Stage II-III Non-small Cell Lung Cancer

for Locally Advanced Lung Non-Small Cell Carcinoma

Sites in Duarte +1 more location

Sponsor: Ohio State University Comprehensive Cancer Center

Sex: All·Age: 18+

Code: NCT05136846·Phase 1·Recruiting·Listed Nov 2021

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Vedolizumab Plus Post-transplant Cyclophosphamide and Short Course Tacrolimus for the Prevention of Graft Versus Host Disease in Patients Undergoing Allogeneic Hematopoietic Cell Transplantation After Reduced Intensity Conditioning

for Acute Lymphoblastic Leukemia

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18 - 80

Code: NCT06815003·Phase 2·Recruiting·Listed Feb 2025

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Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma

for Recurrent Astrocytoma, IDH-Mutant, Grade 3

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06815029·Phase 1·Recruiting·Listed Feb 2025

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FOLFOX, Botensilimab, and Balstilimab for the Treatment of Localized Rectal Cancer Before Surgery

for Rectal Adenocarcinoma

Drug: Botensilimab

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT06780787·Phase 2·Recruiting·Listed Jan 2025

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IVIG for Infection Prevention After CAR-T-Cell Therapy

for Hematologic Malignancies

Sites in Duarte +6 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 18+

Code: NCT05952804·Phase 2·Recruiting·Listed Jul 2023

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Duarte, Los Angeles +31 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Asciminib as Maintenance Treatment After Cellular Therapies for Adults With Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia With t(9

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07040982·Phase 1·Recruiting·Listed Jun 2025

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L-Theanine to Support Relaxation and Mood for Cancer Patients in Surveillance

for Hematopoietic and Lymphatic System Neoplasm

Sites in Duarte, Huntington Beach & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07220447·EARLY_Phase 1·Recruiting·Listed Oct 2025

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Circulating Biomarkers in the Development of Type 1 Diabetes

for Diabetes

1 location in Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT05505669·Recruiting·Listed Aug 2022

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Duarte, La Jolla +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Adding a Live Biotherapeutic Product (CBM588) to Pembrolizumab for the Treatment of Renal Cell Cancer After Surgery

for Clear Cell Renal Cell Carcinoma

Sites in Duarte & Irvine

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07037004·Phase 2·Recruiting·Listed Jun 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Duarte, Baldwin Park +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial