Paid Clinical Trials in Florida

Florida has 4,147 paid clinical trials enrolling now across cities including Miami, Tampa and Jacksonville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Florida include Mayo Clinic Jacksonville, Moffitt Cancer Center and University of Miami Health, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 29, 2026.

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3,687 clinical trials

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Personalized Antibody-Drug Conjugate Therapy Based on RNA and Protein Testing for the Treatment of Advanced or Metastatic Solid Tumors (The ADC MATCH Screening and Treatment Trial)

for Advanced Malignant Solid Neoplasm

Sites in Gainesville +26 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06311214·Phase 2·Recruiting·Listed Mar 2024

Apply to this trial

Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure

for Heart Failure

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 80

Code: NCT06979726·Phase 4·Recruiting·Listed May 2025

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Natural History of Wilson Disease

for Wilson Disease

Sites in Orlando +2 more locations

Sponsor: Yale University

Sex: All·Age: All ages

Code: NCT03334292·Recruiting·Listed Nov 2017

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Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

for Hodgkin Lymphoma

Sites in Miami +2 more locations

Sponsor: University College, London

Sex: All·Age: 16 - 69

Code: NCT04685616·Phase 3·Recruiting·Listed Dec 2020

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Implementing Depression and Adherence Treatment

for Depression

Sites in Miami +1 more location

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT07032363·Recruiting·Listed Jun 2025

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in Tampa, Jacksonville +28 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

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Outcomes in Pediatric and Young Adult B-Cell Malignancies After Commercially Available Immunotherapy

for Lymphoid Leukemia

Sites in Gainesville, St. Petersburg +20 more locations

Sponsor: Stanford University

Sex: All·Age: Up to 26

Code: NCT05865301·Recruiting·Listed May 2023

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Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

for Obesity

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18+

Code: NCT05561595·Recruiting·Listed Sep 2022

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in Miami, Coral Gables +36 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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Osimertinib Alone or With Chemotherapy for EGFR-Mutant Lung Cancers

for Metastatic Non-small Cell Lung Cancer

Drug: Osimertinib

Sites in Tampa +15 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT04410796·Phase 2·Recruiting·Listed Jun 2020

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Miami, Tampa +144 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

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Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

for Osteomyelitis Tibia

Sites in Gainesville, Temple Terrace +12 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05421741·Phase 4·Recruiting·Listed Jun 2022

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Zinc as an Adjunctive Therapy for Cervical Dystonia

for Cervical Dystonia

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 18 - 89

Code: NCT07140874·Phase 2·Recruiting·Listed Aug 2025

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Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients

for Heart Transplant Rejection

Sites in Gainesville, Hollywood +2 more locations

Sponsor: University of Florida

Sex: All·Age: 10 - 21

Code: NCT05732779·Recruiting·Listed Feb 2023

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Trifecta-Heart cfDNA-MMDx Study

for Heart Transplant Rejection

Sites in Tampa +5 more locations

Sponsor: University of Alberta

Sex: All·Age: All ages

Code: NCT04707872·Recruiting·Listed Jan 2021

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Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI

for Carcinoma, Hepatocellular

Sites in Miami +32 more locations

Sponsor: VA Office of Research and Development

Sex: All·Age: 18 - 75

Code: NCT05486572·Recruiting·Listed Aug 2022

Apply to this trial

A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Miami, Tampa +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

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Evaluating a New Therapy for Dry Eye in Patients With Sjögren's Syndrome

for Sjogren Syndrome With Keratoconjunctivitis

1 location in Venice

Sponsor: Center For Sight

Sex: All·Age: 18+

Code: NCT07277257·Phase 4·Recruiting·Listed Dec 2025

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ctDNA to Predict Response to Chemo-Immunotherapy and Detect Minimal Residual Disease in Non-Small Cell Lung Cancer

for Non Small Cell Lung Cancer

1 location in Miami

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT06902272·Phase 2·Recruiting·Listed Mar 2025

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I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer

for Breast Neoplasms

Sites in Tampa +32 more locations

Sponsor: QuantumLeap Healthcare Collaborative

Sex: All·Age: 18+

Code: NCT01042379·Phase 2·Recruiting·Listed Jan 2010

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Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

for Locally Advanced Lung Non-Small Cell Carcinoma

Drug: Sotorasib

Sites in Tampa, Wesley Chapel +7 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07012031·Phase 1, Phase 2·Recruiting·Listed Jun 2025

Apply to this trial

Effectiveness of Interventions to Promote Physical Activity During Pregnancy

for Pregnancy

1 location in Orlando

Sponsor: University of Central Florida

Sex: Female·Age: 18 - 45

Code: NCT07223112·Recruiting·Listed Oct 2025

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Incremental Hemodialysis: The TwoPlus Trial

for End-Stage Kidney Disease

Sites in Jacksonville +9 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05828823·Recruiting·Listed Apr 2023

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A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV

for MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease

Sites in West Palm Beach +9 more locations

Sponsor: Naga P. Chalasani

Sex: All·Age: 18+

Code: NCT07143968·Phase 2·Recruiting·Listed Aug 2025

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Clevidipine for the Antihypertensive Treatment of Acute Intracerebral Hemorrhage

for Intracerebral Hemorrhage

Sites in Tampa, Weston +16 more locations

Sponsor: Zeenat Qureshi Stroke Institute

Sex: All·Age: 18 - 100

Code: NCT06402968·Recruiting·Listed May 2024

Apply to this trial

Functional Incremental Stepping in Place Test (F-IST) Validation

for Intensive Care Medicine

Sites in Boca Raton +1 more location

Sponsor: Kirby Mayer

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06853236·Recruiting·Listed Feb 2025

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Tampa +24 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy

for Metastatic Urothelial Carcinoma

Sites in Miami +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06439836·Phase 1·Recruiting·Listed Jun 2024

Apply to this trial

Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty

for Sleep

1 location in Miami

Sponsor: University of Miami

Sex: All·Age: 18+

Code: NCT06902285·Phase 4·Recruiting·Listed Mar 2025

Apply to this trial

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

for Metastatic Prostate Cancer

Sites in Orlando, Gainesville +15 more locations

Sponsor: VA Office of Research and Development

Sex: Male·Age: 18+

Code: NCT05011383·Phase 2·Recruiting·Listed Aug 2021

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Belatacept in Heart Transplantation

for Heart Transplant

Sites in Tampa +5 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 71

Code: NCT06478017·Phase 2·Recruiting·Listed Jun 2024

Apply to this trial

Abatacept for the Treatment of Common Variable Immunodeficiency With Interstitial Lung Disease

for Interstitial Lung Disease

Sites in Tampa +5 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 4+

Code: NCT04925375·Phase 2·Recruiting·Listed Jun 2021

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Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

for HIV Infection

Sites in Jacksonville +10 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: Up to 48 Hours

Code: NCT02140255·Phase 1, Phase 2·Recruiting·Listed May 2014

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Belimumab With Rituximab for Primary Membranous Nephropathy

for Membranous Nephropathy

Drug: Rituximab

Sites in Miami, Jacksonville +18 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18 - 75

Code: NCT03949855·Phase 2·Recruiting·Listed May 2019

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Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial

for Recurrent Castration-Sensitive Prostate Carcinoma

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: Male·Age: 18+

Code: NCT06378866·Phase 2·Recruiting·Listed Apr 2024

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Dominantly Inherited Alzheimer Network (DIAN)

for Alzheimer's Disease

Sites in Jacksonville +6 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00869817·Recruiting·Listed Mar 2009

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Trial of Exercise and Lifestyle for Women With Ovarian and Endometrial Cancer

for Ovarian Cancer

Sites in Miami +1 more location

Sponsor: Yale University

Sex: Female·Age: 18+

Code: NCT05761561·Recruiting·Listed Mar 2023

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A First-in-Human Study of FID-022 in Solid Tumor Patients

for Pancreatic Cancer

1 location in Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18+

Code: NCT07249775·Recruiting·Listed Nov 2025

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Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease

for Muscle-Invasive Bladder Carcinoma

Sites in Orlando +2 more locations

Sponsor: Washington University School of Medicine

Sex: All·Age: 18+

Code: NCT06529822·Phase 1·Recruiting·Listed Jul 2024

Apply to this trial

Biomechanics/Motion Analysis Laboratory Data Bank

for Kinematics

1 location in Gainesville

Sponsor: University of Florida

Sex: All·Age: 2 - 75·Accepts healthy volunteers

Code: NCT00160771·Recruiting·Listed Sep 2005

Apply to this trial