Paid Clinical Trials in Greenville, SC

As of September 2026, 264 paid clinical trials are recruiting in Greenville, South Carolina. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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251 clinical trials

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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

for Ulcerative Colitis

Drug: Risankizumab

Sites in Greenville +11 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 17

Code: NCT07071519·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCD

for Sickle Cell Disease

Sites in Greenville, Simpsonville +33 more locations

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT05431088·Phase 2, Phase 3·Recruiting·Listed Jun 2022

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A Study of JNJ-88549968 for the Treatment of Calreticulin (CALR)-Mutated Myeloproliferative Neoplasms

for Neoplasms

Sites in Greenville +14 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT06150157·Phase 1·Recruiting·Listed Nov 2023

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Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

Sites in Greenville +20 more locations

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

for Non Small Cell Lung Cancer

Sites in Greenville +21 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT05983432·Phase 1·Recruiting·Listed Aug 2023

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FebriDx® Pediatric Validation Study

for Acute Respiratory Infections (ARIs)

Sites in Greenville, Charleston +8 more locations

Sponsor: Lumos Diagnostics

Sex: All·Age: 2 - 11

Code: NCT07211997·Recruiting·Listed Oct 2025

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Evaluating BL-M14D1 in Subjects With Locally Advanced or Metastatic Small Cell Lung Cancer and Neuroendocrine Tumors

for Small Cell Lung Cancer Metastatic or Locally Advanced

Sites in Greenville +23 more locations

Sponsor: SystImmune Inc.

Sex: All·Age: 18+

Code: NCT07080242·Phase 1·Recruiting·Listed Jul 2025

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A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis

for Multiple Sclerosis (MS) Primary Progressive

Sites in Greenville +17 more locations

Sponsor: Zenas BioPharma (USA), LLC

Sex: All·Age: 18 - 60

Code: NCT07067463·Phase 3·Recruiting·Listed Jul 2025

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Total Shoulder Arthroplasty Multi-Center Registry

for Shoulder Arthroplasty

Sites in Greenville +15 more locations

Sponsor: Arthrex, Inc.

Sex: All·Age: 18 - 100

Code: NCT03511586·Recruiting·Listed Apr 2018

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A Study of the Medicine Called Abrocitinib in Children 6 to Less Than 12 Years of Age With Moderate-to-Severe Eczema

for Eczema

Sites in Greenville, Charleston +11 more locations

Sponsor: Pfizer

Sex: All·Age: 6 - 11

Code: NCT06807268·Phase 3·Recruiting·Listed Feb 2025

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A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

for Pneumococcal Infection

Sites in Greenville, Spartanburg +12 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 2 Months - 15 Months·Accepts healthy volunteers

Code: NCT07300267·Phase 1·Recruiting·Listed Dec 2025

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Exactech Shoulder Post Market Clinical Follow-up Study

for Osteo Arthritis Shoulders

Sites in Greenville, Charleston +22 more locations

Sponsor: Exactech

Sex: All·Age: 21+

Code: NCT05603728·Recruiting·Listed Nov 2022

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A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

for Anemia, Sickle Cell

Sites in Greenville +17 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06481306·Phase 1, Phase 2·Recruiting·Listed Jul 2024

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A Study of CHS-114 (Tagmokitug) in Combination With Toripalimab and/or Other Treatments in Participants With Advanced Solid Tumors

for Metastatic Solid Tumor

Sites in Greenville +17 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 18+

Code: NCT06657144·Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Study of SLS009 (Formerly GFH009) a Potent Highly Selective CDK9 Inhibitor in Patients With Hematologic Malignancies and High-Risk Newly Diagnosed AML

for Hematologic Malignancies

Sites in Greenville +15 more locations

Sponsor: Sellas Life Sciences Group

Sex: All·Age: 12+

Code: NCT04588922·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

for Systemic Lupus Erythematosus (With and Without Nephritis)

Sites in Greenville, Charleston +14 more locations

Sponsor: Allogene Therapeutics

Sex: All·Age: 18 - 74

Code: NCT07085104·Phase 1·Recruiting·Listed Jul 2025

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The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease

for Sickle Cell Disease

Sites in Greenville +15 more locations

Sponsor: Sanofi

Sex: All·Age: 10 - 65

Code: NCT06975865·Phase 3·Recruiting·Listed May 2025

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The Artisse™ Intrasaccular Device is Indicated for the Treatment of Wide-neck Bifurcating Intracranial Aneurysms (IAs).

for Intracranial Aneurysm

Sites in Greenville +23 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 18 - 75

Code: NCT02998229·Recruiting·Listed Dec 2016

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A Study to Assess the Safety and Risk of Hypersensitivity Reactions of Sulbactam-durlobactam in Adults With Acinetobacter Baumannii-calcoaceticus (ABC) Complex Infection

for Acinetobacter Baumannii-calcoaceticus Complex Infection (ABC)

Sites in Greenville +11 more locations

Sponsor: Innoviva Specialty Therapeutics

Sex: All·Age: 18+

Code: NCT06746883·Recruiting·Listed Dec 2024

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A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors Cancer

Sites in Greenville +9 more locations

Sponsor: Nimbus Wadjet, Inc.

Sex: All·Age: 18 - 99

Code: NCT06898450·Phase 1, Phase 2·Recruiting·Listed Mar 2025

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities

for Actinic Keratosis

Sites in Greenville, Anderson +18 more locations

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144852·Phase 3·Recruiting·Listed Aug 2025

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Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp

for Actinic Keratosis

Sites in Greenville +9 more locations

Sponsor: Sun Pharmaceutical Industries, Inc.

Sex: All·Age: 18 - 85

Code: NCT07144345·Phase 3·Recruiting·Listed Aug 2025

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The MIRROR Registry: Minimally Invasive IntRaceRebral HemORrhage Evacuation

for Supratentorial Hemorrhage

Sites in Greenville +17 more locations

Sponsor: Integra LifeSciences Corporation

Sex: All·Age: 18+

Code: NCT04494295·Recruiting·Listed Jul 2020

Apply to this trial

Pompe Pregnancy Sub-Registry

for Glycogen Storage Disease Type II (GSD-II)

Sites in Greenville +13 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: Female·Age: All ages

Code: NCT00567073·Recruiting·Listed Dec 2007

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Long-Term Stability of the Glide Control Strategy

for Upper Limb Amputation Above Elbow

Sites in Greenville, Anderson +8 more locations

Sponsor: Infinite Biomedical Technologies

Sex: All·Age: 18+

Code: NCT07222085·Recruiting·Listed Oct 2025

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A Study to Evaluate the Safety and Effectiveness of the InnAVasc Arteriovenous Graft for Hemodialysis Access in Patients With End-Stage Renal Disease

for End Stage Renal Disease (ESRD)

Sites in Greenville, Orangeburg +18 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 90

Code: NCT04671771·Recruiting·Listed Dec 2020

Apply to this trial

Maturation of Arteriovenous Fistula With Automated Sonography Assessments Trial

for Diabetes

Sites in Greenville, Orangeburg +18 more locations

Sponsor: Sonavex, Inc.

Sex: All·Age: 18 - 84

Code: NCT06190717·Recruiting·Listed Jan 2024

Apply to this trial

Serranator POINT FORCE Registry

for Peripheral Artery Disease (PAD)

Sites in Greenville +17 more locations

Sponsor: Cagent Vascular LLC

Sex: All·Age: 18+

Code: NCT06687590·Recruiting·Listed Nov 2024

Apply to this trial

Safety, PK, and Preliminary Efficacy of MBRC-101 in Advanced Refractory Solid Tumors

for Cancer

Sites in Greenville, Charleston +13 more locations

Sponsor: MBrace Therapeutics

Sex: All·Age: 18+

Code: NCT06014658·Phase 1, Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

for Myasthenia Gravis

Sites in Greenville +5 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07673744·Phase 2·Recruiting·Listed Jun 2026

Apply to this trial

A Phase 1/2 Study of KK2430 in Participants With Hematologic Neoplasms

for Hematologic Neoplasms

1 location in Greenville

Sponsor: Kyowa Kirin Co., Ltd.

Sex: All·Age: 18+

Code: NCT07629726·Phase 1, Phase 2·Recruiting·Listed Jun 2026

Apply to this trial

A Phase 1 Study of the Safety and Tolerability of CTX-10726

for Gastroesophageal Cancer (GC)

Drug: CTX-10726

Sites in Greenville +4 more locations

Sponsor: Compass Therapeutics

Sex: All·Age: 18+

Code: NCT07419841·Phase 1·Recruiting·Listed Feb 2026

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Managing Pain Using Optimized Sequences by Adjusting Parameters With Independent Current Control

for Chronic Pain

Sites in Greenville +6 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07190807·Recruiting·Listed Sep 2025

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A Long-term Study of the Medicine Called Abrocitinib in Children Aged 2 Years and Older With Moderate to Severe Eczema

for Atopic Dermatitis

Sites in Greenville, Charleston +9 more locations

Sponsor: Pfizer

Sex: All·Age: 2 - 11

Code: NCT06807281·Phase 3·Recruiting·Listed Feb 2025

Apply to this trial

EVERO Drug-coated Balloon (DCB) Randomized Trial

for Peripheral Vascular Disease

Sites in Greenville +9 more locations

Sponsor: Cook Research Incorporated

Sex: All·Age: 18+

Code: NCT07144150·Recruiting·Listed Aug 2025

Apply to this trial

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

for Amputation

Sites in Greenville +5 more locations

Sponsor: AtriCure, Inc.

Sex: All·Age: 18+

Code: NCT06908538·Recruiting·Listed Apr 2025

Apply to this trial

GORE® ENFORM Biomaterial Product Study

for Hernia, Ventral

Sites in Greenville +6 more locations

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18+

Code: NCT04718168·Recruiting·Listed Jan 2021

Apply to this trial

NV PSR INSPIRE-A Pipeline™ Vantage Post Approval Study

for Intracranial Aneurysm

Sites in Greenville +7 more locations

Sponsor: Medtronic Neurovascular Clinical Affairs

Sex: All·Age: 22+

Code: NCT06604884·Recruiting·Listed Sep 2024

Apply to this trial

Integrity Implant System Post Market Clinical Follow-Up Study

for Rotator Cuff Tears of the Shoulder

Sites in Greenville +8 more locations

Sponsor: Anika Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06741527·Recruiting·Listed Dec 2024

Apply to this trial

Study of Patritumab Deruxtecan With Other Anticancer Agents in Participants With HER2 Positive Breast Cancer That Has Spread and Cannot Be Surgically Removed (MK-1022-009)

for Breast Neoplasms

Sites in Greenville +4 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06686394·Phase 1, Phase 2·Recruiting·Listed Nov 2024

Apply to this trial