Paid Clinical Trials in Hershey, PA

As of September 2026, 268 paid clinical trials are recruiting in Hershey, Pennsylvania. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 24, 2026.

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246 clinical trials

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VIBRANT: VIB4920 for Active Lupus Nephritis

for Lupus Nephritis

Sites in Hershey, Philadelphia +14 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 18+

Code: NCT05201469·Phase 2·Recruiting·Listed Jan 2022

Apply to this trial

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

Sites in Hershey, Philadelphia +33 more locations

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting·Listed Aug 2020

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Trial of Pre-operative Neratinib and Endocrine Therapy With Trastuzumab in ER-Positive, HER-2 Positive Breast Cancers

for Breast Cancer

Sites in Hershey +3 more locations

Sponsor: Ruth O'Regan

Sex: All·Age: 18+

Code: NCT04886531·Phase 2·Recruiting·Listed May 2021

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Safety and Efficacy of AGN-INM176 in Prostate Patients With Rising PSA

for Prostate Cancer

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: Male·Age: 40+

Code: NCT06600698·Phase 1, Phase 2·Recruiting·Listed Sep 2024

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Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

for Rectal Cancer

Sites in Hershey, Chadds Ford +101 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT06205485·Phase 3·Recruiting·Listed Jan 2024

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

Sites in Hershey, Lebanon +705 more locations

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting·Listed Apr 2021

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Ribociclib And Endocrine Treatment of Physician's Choice for Locoregional Recurrent, Resected Hormone Receptor Positive HER2 Negative Breast Cancer

for Locoregional Recurrence

Drug: Ribociclib

Sites in Hershey +18 more locations

Sponsor: Oana Danciu

Sex: All·Age: 18+

Code: NCT05467891·Phase 2·Recruiting·Listed Jul 2022

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Evaluation of Structural and Functional Integrity of the Rotator Cuff After Total Shoulder Arthroplasty

for Osteoarthritis of Shoulder

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 45+

Code: NCT03921944·Recruiting·Listed Apr 2019

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ASSESS ALL ALS Study

for Amyotrophic Lateral Sclerosis

Sites in Hershey, Philadelphia +34 more locations

Sponsor: St. Joseph's Hospital and Medical Center, Phoenix

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06578195·Recruiting·Listed Aug 2024

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Optimizing Pain Treatment in Children On Mechanical Ventilation

for Mechanical Ventilation

Sites in Hershey, Philadelphia +14 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 2 Months - 17

Code: NCT06994442·Phase 3·Recruiting·Listed May 2025

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Impact of Brief Daily Functional Resistance Training on Lower Extremity Physical Performance

for Mobility Limitation

Sites in Hershey & Pittsburgh

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 65+

Code: NCT06396247·Phase 2, Phase 3·Recruiting·Listed May 2024

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Limiting Emergence Phenomena After General Anesthesia With Combined LMA and ETT Airway Management Technique

for Limit Emergence Phenomena After General Anesthesia

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT02708836·Recruiting·Listed Mar 2016

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

Sites in Hershey, Philadelphia +140 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting·Listed Apr 2019

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Health-E You Efficacy Trial for Male Adolescents

for Sexually Transmitted Diseases

Sites in Hershey, Philadelphia +6 more locations

Sponsor: Johns Hopkins University

Sex: Male·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06525064·Recruiting·Listed Jul 2024

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TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II

for Lymphoblastic Leukemia

Sites in Hershey +16 more locations

Sponsor: Tanja Andrea Gruber

Sex: All·Age: Up to 1

Code: NCT05848687·Phase 1, Phase 2·Recruiting·Listed May 2023

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The Venous Distension Reflex and Orthostatic Hypertension

for Blood Pressure

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03496792·Recruiting·Listed Apr 2018

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Autonomic Control of the Circulation and VDR

for Venous Distension Reflex

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 35·Accepts healthy volunteers

Code: NCT03513770·EARLY_Phase 1·Recruiting·Listed May 2018

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A Clinical Trial of Early Ventilation in Amyotrophic Lateral Sclerosis (EVENT ALS)

for Amyotrophic Lateral Sclerosis (ALS)

Sites in Hershey, Philadelphia & Philadelphi

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT07071935·Phase 2·Recruiting·Listed Jul 2025

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Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

for Deep Venous Thrombosis

Sites in Hershey, Philadelphia +18 more locations

Sponsor: Yale University

Sex: All·Age: Up to 17

Code: NCT04924322·Phase 2, Phase 3·Recruiting·Listed Jun 2021

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Development of a College Student-Delivered Cognitive-Behavioral Therapy (CBT) Intervention for Rural High School Students

for Depression

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 13 - 18

Code: NCT07240792·Recruiting·Listed Nov 2025

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Developing an Artificial Intelligence (AI) Chatbot for Adolescents and Young Adults With Eating Disorders

for Eating Disorders

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 12 - 26

Code: NCT07237607·Recruiting·Listed Nov 2025

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Hershey, Lebanon +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Hershey, Philadelphia +58 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Little Cigar Oxidants

for Tobacco Use

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21 - 65

Code: NCT06310187·Recruiting·Listed Mar 2024

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Left Atrial Imaging Prior to Cardioversion: Leveraging Computed Tomography to Rule Out Thrombus in The Emergency Department (LA CLOTTED)

for Atrial Fibrillation (AF)

1 location in Hershey

Sponsor: Ottawa Heart Institute Research Corporation

Sex: All·Age: 18+

Code: NCT07002450·Recruiting·Listed Jun 2025

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Liposomal Bupivacaine Versus Plain Bupivacaine After Intercostal Injections For Pain Management After Thoracoscopy

for Pain, Postoperative

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT03737292·Phase 4·Recruiting·Listed Nov 2018

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Intramedullary Calcium Sulfate Antibiotic Depot

for Open tíbia Fracture

Sites in Hershey +9 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT05766670·Phase 3·Recruiting·Listed Mar 2023

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in Hershey +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

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Ultrasound (US) Guided External Ventricular Catheter Placement

for Hydrocephalus

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06253858·Recruiting·Listed Feb 2024

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Study of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and Efficacy

for Acute Myeloid Leukemia

Sites in Hershey +8 more locations

Sponsor: Norman J. Lacayo

Sex: All·Age: Up to 21

Code: NCT05101551·Phase 1·Recruiting·Listed Nov 2021

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

Sites in Hershey +12 more locations

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting·Listed Mar 2020

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Single Versus Dual Implant Fixation of Distal Femur Fractures

for Articular Fractures

Sites in Hershey +15 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06286670·Recruiting·Listed Feb 2024

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CBG/CBD Oil for Chemotherapy-Induced Peripheral Neuropathy

for Chemotherapy-Induced Peripheral Neuropathy

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 21+

Code: NCT07016971·Phase 1·Recruiting·Listed Jun 2025

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S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for Cardiotoxicity

Sites in Hershey, Allentown +142 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03418961·Phase 3·Recruiting·Listed Feb 2018

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Comparison of EVAR and ESAR for Infrarenal Aortic Aneurysms With a Wide Proximal Neck

for Aortic Aneurysm, Abdominal

Sites in Hershey +15 more locations

Sponsor: Rijnstate Hospital

Sex: All·Age: 18+

Code: NCT05484115·Recruiting·Listed Aug 2022

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Adapting Exposure for Adolescent AN

for Anorexia Nervosa

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 14 - 17

Code: NCT07188155·Recruiting·Listed Sep 2025

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A Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention for Improving Physical Activity in Hispanic or Latino/Latina Adolescent and Young Adult Childhood Cancer Survivors, Walking Juntos Study

for Hematopoietic and Lymphatic System Neoplasm

Sites in Hershey, Philadelphia +74 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 15 - 20

Code: NCT06410209·Phase 2·Recruiting·Listed May 2024

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Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

for Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

Sites in Hershey, Philadelphia +30 more locations

Sponsor: Nationwide Children's Hospital

Sex: All·Age: 1 Day - 17

Code: NCT05267821·Phase 2, Phase 3·Recruiting·Listed Mar 2022

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SSVC-CI During CABG

for Coronary Artery Bypass Grafting Surgery (CABG)

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18+

Code: NCT06645327·Recruiting·Listed Oct 2024

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Pain and Disability Outcomes in Post Amputation Patients

for Limb Pain, Phantom

1 location in Hershey

Sponsor: Milton S. Hershey Medical Center

Sex: All·Age: 18 - 89

Code: NCT05716321·Recruiting·Listed Feb 2023

Apply to this trial