Solid tumor Clinical Trials in Houston, TX

As of July 2026, 184 paid clinical trials are recruiting for Solid tumor in Houston, Texas. Recruiting Solid tumor studies evaluate investigational treatments, diagnostics, and supportive care approaches to improve patient outcomes. Compensation typically covers time, travel, and study visits, and many studies also include study-related medical care at no cost.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 17, 2026.

Related specialties in Houston

Oncology· 1,560

Filter results

Filter results

State

City

Facility

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

184 clinical trials for Solid tumor

·Clear filters·↓ Download CSV

Safety, Pharmacokinetics, and Efficacy of AI-081, a Bispecific Antibody for PD-1 And VEGF in Advanced Solid Tumors

for Advanced Solid Tumor

Drug: AI-081

Sites in Houston +18 more locations

Sponsor: OncoC4, Inc.

Sex: All·Age: 18+

Code: NCT06635785·Phase 1, Phase 2·Recruiting·Listed Oct 2024

Apply to this trial

A Study of YL201 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston, Tyler +17 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT05434234·Phase 1, Phase 2·Recruiting·Listed Jun 2022

Apply to this trial

A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors

for Advanced Solid Tumors With KRAS G12C Mutations

Sites in Houston, San Antonio +10 more locations

Sponsor: Frontier Medicines Corporation

Sex: All·Age: 18+

Code: NCT06244771·Phase 1, Phase 2·Recruiting·Listed Feb 2024

Apply to this trial

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

for Non Small Cell Lung Cancer

Sites in Houston +14 more locations

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06810544·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

for Locally Advanced Solid Tumor

Sites in Houston +16 more locations

Sponsor: Nuvalent Inc.

Sex: All·Age: 18+

Code: NCT06521554·Phase 1·Recruiting·Listed Jul 2024

Apply to this trial

A Study of Valemetostat Tosylate in Combination With DXd ADCs in Subjects With Solid Tumors

for Advanced Solid Tumor

Sites in Houston, Dallas +14 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06244485·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

for Advanced Solid Tumor

Sites in Houston, Dallas +19 more locations

Sponsor: Clasp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06778863·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

JZP898 Intravenous Infusion as Monotherapy and Combination With Pembrolizumab in Adults With Advanced/Metastatic Solid Tumors

for Advanced Solid Tumor

Sites in Houston, Dallas +8 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06108050·Phase 1·Recruiting·Listed Oct 2023

Apply to this trial

Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston, San Antonio +7 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT05007782·Phase 1·Recruiting·Listed Aug 2021

Apply to this trial

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

for Ovarian Cancer

Sites in Houston, San Antonio +12 more locations

Sponsor: OnCusp Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06234423·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

A Study to Evaluate the Safety of INCA33890 in Participants With Advanced or Metastatic Solid Tumors

for Solid Tumors

Sites in Houston, San Antonio +9 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT05836324·Phase 1·Recruiting·Listed May 2023

Apply to this trial

A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston, San Antonio +11 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT06859762·Phase 1·Recruiting·Listed Mar 2025

Apply to this trial

First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer

for PIK3CA Mutation

Sites in Houston, Dallas +21 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05216432·Phase 1·Recruiting·Listed Jan 2022

Apply to this trial

Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer

for Advanced Solid Tumor

Sites in Houston, Austin +9 more locations

Sponsor: Aulos Bioscience, Inc.

Sex: All·Age: 18+

Code: NCT05267626·Phase 1, Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

for Advanced Solid Tumor

Sites in Houston, San Antonio +8 more locations

Sponsor: Circle Pharma

Sex: All·Age: 12+

Code: NCT06577987·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Houston, San Antonio +16 more locations

Sponsor: Marengo Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05592626·Phase 1, Phase 2·Recruiting·Listed Oct 2022

Apply to this trial

A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

Sites in Houston +19 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting·Listed Jun 2021

Apply to this trial

A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies

for Solid Tumor, Adult

Sites in Houston +12 more locations

Sponsor: GV20 Therapeutics

Sex: All·Age: 18+

Code: NCT05669430·Phase 1, Phase 2·Recruiting·Listed Dec 2022

Apply to this trial

FT825/ONO-8250, an Off-the-Shelf, HER2 CAR-T, With or Without Monoclonal Antibodies in Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston +13 more locations

Sponsor: Fate Therapeutics

Sex: All·Age: 18+

Code: NCT06241456·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

A Study to Evaluate Tovorafenib in Pediatric and Young Adult Participants With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors

for Low-grade Glioma

Sites in Houston +11 more locations

Sponsor: Day One Biopharmaceuticals, Inc.

Sex: All·Age: 6 Months - 25

Code: NCT04775485·Phase 2·Recruiting·Listed Mar 2021

Apply to this trial

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

for Advanced Solid Tumor

Sites in Houston +12 more locations

Sponsor: Volastra Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT05902988·Phase 1, Phase 2·Recruiting·Listed Jun 2023

Apply to this trial

Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors

for Advanced Solid Tumors

Drug: Ivonescimab

Sites in Houston, San Antonio +4 more locations

Sponsor: Revolution Medicines, Inc.

Sex: All·Age: 18+

Code: NCT07397338·Phase 1, Phase 2·Recruiting·Listed Feb 2026

Apply to this trial

Study in Advanced Solid Tumor Patients

for Advanced Solid Tumor

Sites in Houston, San Antonio +3 more locations

Sponsor: Callio Therapeutics

Sex: All·Age: 18+

Code: NCT07300943·Phase 1, Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

A Study of PARG Inhibitor FORX-428 in Patients With Advanced Solid Tumors.

for Advanced Solid Tumors

Sites in Houston, San Antonio +6 more locations

Sponsor: FoRx Therapeutics AG

Sex: All·Age: 18+

Code: NCT07356453·Phase 1·Recruiting·Listed Jan 2026

Apply to this trial

A Study of BG-75098 Alone and in Combination With Other Agents in Adults With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston +5 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07226349·Phase 1·Recruiting·Listed Nov 2025

Apply to this trial

A Study to Assess the Safety, Tolerability, Pharmacokinetic, Pharmacodynamic, Immunogenicity and Antitumour Activity of IPN60300 in Adults With Locally Advanced or Metastatic Solid Tumours

for Locally Advanced Solid Tumor

Sites in Houston, San Antonio +4 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213817·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

for Advanced Solid Tumor

Sites in Houston, San Antonio +4 more locations

Sponsor: Ipsen

Sex: All·Age: 18+

Code: NCT07213830·Phase 1, Phase 2·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Evaluate INCA036873 in Participants With Advanced Solid Tumors and Hematological Malignancies

for Solid Tumors

Sites in Houston +7 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT07195916·Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

EIK1005-002: A Clinical Research Study Evaluating EIK1005, a Werner Helicase Inhibitor, as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors Including Microsatellite Instability High (MSI-H) Tumors

for Advanced Solid Tumors

Sites in Houston +2 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18+

Code: NCT07262619·Phase 1, Phase 2·Recruiting·Listed Dec 2025

Apply to this trial

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

for Breast Cancer

Sites in Houston, Austin +4 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07222267·Phase 1·Recruiting·Listed Oct 2025

Apply to this trial

A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies

for Advanced Solid Tumors

Sites in Houston +5 more locations

Sponsor: SEED Therapeutics, Inc.

Sex: All·Age: 16+

Code: NCT07197554·Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

A First-in-Human Study of BG-C0902 Alone and in Combination With Other Therapeutic Agents in Patients With Advanced Solid Tumors

for Solid Tumors

Sites in Houston, San Antonio +1 more location

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07181681·Phase 1·Recruiting·Listed Sep 2025

Apply to this trial

A Rollover Study Evaluating Sotorasib With or Without Panitumumab in Participants With KRAS p.G12C Mutation

for Advanced Solid Tumors

Drug: Sotorasib

Sites in Houston +1 more location

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT07172919·Phase 2·Recruiting·Listed Sep 2025

Apply to this trial

A Study to Evaluate the Safety and Efficacy of MK-3120 in Participants With Advanced Solid Tumors (MK-3120-002)

for Advanced Solid Tumors

Sites in Houston, Austin +5 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06818643·Phase 1, Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer

for Advanced Solid Tumors

Sites in Houston, San Antonio +4 more locations

Sponsor: Accent Therapeutics

Sex: All·Age: 18+

Code: NCT06799065·Phase 1·Recruiting·Listed Jan 2025

Apply to this trial

BTM-3566 in Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Houston & San Antonio

Sponsor: Bantam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07266285·Phase 1·Recruiting·Listed Dec 2025

Apply to this trial

SNV1521 in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston +4 more locations

Sponsor: Synnovation Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06220864·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

for Advanced Solid Tumor

Sites in Houston, San Antonio +3 more locations

Sponsor: Adcendo ApS

Sex: All·Age: 18+

Code: NCT06597721·Phase 1·Recruiting·Listed Sep 2024

Apply to this trial

SW-682 in Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Houston, Dallas +6 more locations

Sponsor: SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany

Sex: All·Age: 18+

Code: NCT06251310·Phase 1·Recruiting·Listed Feb 2024

Apply to this trial

A Study of BG-C477 in Participants With Advanced Solid Tumors

for Advanced Solid Tumors

Sites in Houston, Longview +7 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT06596473·Phase 1·Recruiting·Listed Sep 2024

Apply to this trial