Paid Clinical Trials in Houston, TX
As of September 2026, 3,048 paid clinical trials are recruiting in Houston, Texas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Houston offers studies at sites including MD Anderson Cancer Center for conditions such as Breast Cancer, Acute Myeloid Leukemia, Advanced Solid Tumor, Colorectal Cancer. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Houston
Trials by drug in Houston
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Newly added in Houston
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
Prospective Observational Study Of Geniculate Artery Embolization For Symptomatic Knee Osteoarthritis In A Cancer Population
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
Nasal Dilator Therapy for Patulous Eustachian Tube Dysfunction
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
2,718 clinical trials
A Study to Evaluate the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of Migraine
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
Study to Learn About Safety, Tolerability, and Immune Response of a Catch-up Pneumococcal Vaccine in Children and Adolescents
A Study to Learn About How a New Pneumococcal Vaccine Works in Infants.
A Study to Evaluate Efficacy, Safety, and Immunogenicity With ABP 938 8 mg Versus EYLEA® HD (Aflibercept) in Participants With Neovascular Age-related Macular Degeneration
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight
A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
Implementation Study of Lenacapavir Pre-exposure Prophylaxis for HIV Prevention
Phase 3 Study of Telitacicept in Active Primary Sjögren's Disease
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study of Brenipatide in Participants With Opioid Use Disorder
A Trial to Investigate Safety, Exposure, and Efficacy of HU6 Compared With Placebo in Adult Participants With Metabolic Dysfunction-associated Steatohepatitis (MASH)
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
A Study to Test Whether Different Doses of BI 3000202 Help People With Systemic Lupus Erythematosus (SLE)
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
An Evaluation of the Safety and Efficacy of TSND-201 for the Treatment of PTSD (EMPOWER-1)
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
A Study to Evaluate Pumitamig Versus Durvalumab Following Concurrent Chemoradiation Therapy in Participants With Unresectable Stage III Non-small Cell Lung Cancer (NSCLC) (ROSETTA Lung-201)
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
PODOMOUNT-Basket, a Study to Test Whether BI 764198 Helps Adults and Adolescents With Different Types of Kidney Disease
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
A Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)
A Study to Learn About a Clostridioides Difficile Vaccine in People 65 Years of Age and Older
Trial Against INtractable Type 2 Diabetes (CAPTAIN-T2D)
A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
Effectiveness and Adverse-effect Switch Evaluation of Xanomeline and Trospium Chloride (KarXT)
A Study to Test Whether BI 3802876 is Tolerated in People With Compensated Liver Cirrhosis Due to Metabolic Dysfunction- Associated Steatohepatitis (MASH)
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Top Research Study Locations in Houston
Researchers run research studies in Houston, TX at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| MD Anderson Cancer Center | Colorectal Cancer, Ovarian Cancer, Acute Myeloid Leukemia | 409 |
| M D Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Acute Myeloid Leukemia, Malignant Solid Neoplasm | 251 |
| Baylor College of Medicine | Epilepsy, Heart Failure, Anxiety Disorders | 193 |
| The University of Texas Health Science Center at Houston | Cluster Headache, HIV Infections, Systemic Sclerosis | 184 |
| The University of Texas MD Anderson Cancer Center | Advanced Solid Tumor, Breast Cancer, Colorectal Cancer | 135 |
| Houston Methodist Hospital | Acute Respiratory Distress Syndrome, ARDS, ARDS (Acute Respiratory Distress Syndrome) | 128 |
| Texas Children's Hospital | Diffuse Intrinsic Pontine Glioma, High Grade Glioma, WHO Grade III Glioma | 110 |
| The University of Texas M. D. Anderson Cancer Center | Cancer, Breast Cancer, Prostate Cancer | 85 |
| University of Texas MD Anderson Cancer Center | Breast Cancer, Non-small Cell Lung Cancer, Chronic Lymphocytic Leukemia | 81 |
| UT MD Anderson Cancer Center | Metastatic Malignant Solid Neoplasm, Unresectable Malignant Solid Neoplasm, Malignant Solid Neoplasm | 75 |
| Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Anatomic Stage II Breast Cancer AJCC v8 | 57 |
| MD Anderson | Myelodysplastic Syndromes, Myelofibrosis, Acute Myeloid Leukemia | 39 |
| Houston Methodist | Heart Failure, Cardiovascular Diseases, Heart Valve Diseases | 33 |
| Michael E. DeBakey VA Medical Center, Houston, TX | Spinal Cord Injury, Metastatic Prostate Cancer, Stress Disorders, Post-Traumatic | 31 |
| University of Texas Health Science Center at Houston | Infant, Small for Gestational Age, Infant, Low Birth Weight, Infant, Newborn | 29 |
| UT MD Anderson | Breast Cancer, Pancreatic Cancer, AML | 27 |
| Ben Taub General Hospital | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8 | 25 |
| Houston Methodist Research Institute | Hepatocellular Carcinoma, AAA, AAA - Abdominal Aortic Aneurysm | 22 |
| GSK Investigational Site | Chickenpox, HIV Infections, Gastrointestinal Neoplasms | 19 |
| The University of Texas M.D. Anderson Cancer Center | Advanced Breast Cancer, Breast Cancer, Metastatic Breast Cancer | 17 |
| Houston Methodist West Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, AL Amyloidosis | 16 |
| UTHealth Houston | Acute Suicidal Depression (ASD), Charcot-Marie-Tooth Disease Type 2D, Emergency Department Visits | 16 |
| Michael E. DeBakey VA Medical Center | Gulf War Syndrome, Adult Growth Hormone Deficiency, Alzheimer Disease | 15 |
| Memorial Hermann Texas Medical Center | Acute Kidney Injury, Ischemic Stroke, Ovarian Carcinoma | 14 |
| Md Anderson Cancer Center | Solid Tumors, Chronic Lymphocytic Leukemia, Mantle Cell Lymphoma | 13 |
Active & Upcoming Studies in Houston (2026)
Recruiting trials in Houston grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (1,179 active studies)
- A Phase 1 Open-Label, Dose-Ranging Safety and Pharmacokinetics Study of Oral Cladribine in Patients With Acute Myeloid Leukemia (AML) · Phase 1, Phase 2 · M.D. Anderson Cancer Center
- Randomized Phase 2 Study Of Epcoritamab Vs Watch And Wait InPatients With Previously Untreated Low Tumor Burden FollicularLymphoma · Phase 2 · M.D. Anderson Cancer Center
Neurology & pain (139 active studies)
- Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction in Chronic Stroke · EARLY_Phase 1 · University of Houston
- Prospective Randomized Study of TPS + CBT VS TPS Alone: Readmission, Opioid Use, and Chronic Pain · M.D. Anderson Cancer Center
Diabetes & metabolic (105 active studies)
- Benefits of Insoles With Real-Time Alert and Foot Self-Care Education · Texas Woman's University
- Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study · Endogenex, Inc.
Cardiovascular (103 active studies)
- Novel Technologies to Improve Echocardiographic Estimates of Left Ventricular Filling Pressure in Heart Failure Combined With Atrial Fibrillation · Oslo University Hospital
- HiCM-188 Cell Therapy in Adults With Advanced Heart Failure Undergoing Heart Bypass Surgery · Phase 1, Phase 2 · HELP Therapeutics Co., Ltd.
Mental health & behavior (81 active studies)
- ACT for Veterans With IBD and Mental Health Challenges · VA Office of Research and Development
- Pilot Randomized Trial of BA-GSH in VA PC-MHI · VA Office of Research and Development
Pediatric (45 active studies)
- Food is Medicine in Survivorship: Examining the Feasibility and Impact of a Scalable Food Delivery and Culinary Medicine Program (FoodiiS) Among Pediatric Cancer Survivors and Their Families · M.D. Anderson Cancer Center
- Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements · Kenneth Moise MD
HIV / STI (34 active studies)
- Improving HIV Prevention and Substance Use Post-Sexual Assault Services · The University of Texas Health Science Center, Houston
- A Study to Evaluate the Safety and Antiviral Activity of Two Human Monoclonal Antibodies (VRC07-523LS and PGT121.414.LS) During Analytic Treatment Interruption in Participants Living With HIV Who Initiated ART During Acute/Early HIV-1 Infection · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
Vaccines (26 active studies)
- A Safety, Reactogenicity and Immunogenicity Trial of RVX-sCPD9 Booster Intranasal COVID-19 Vaccine · Phase 1 · National Institute of Allergy and Infectious Diseases (NIAID)
- A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age · Phase 3 · GlaxoSmithKline
Eye & vision (23 active studies)
- Treating Contact Lens Discomfort With Varenicline Solution Nasal Spray 0.03mg · Ocular Aesthetics, LLC dba Ocular Clinical Trials
- A Comparative, Randomized, Investigator-blind, Active-controlled, Parallel-group, Multicenter, Clinical Endpoint Study · Phase 3 · YS Life Science Co., Ltd.
Common conditions studied in Houston
- Breast Cancer (77 active studies)
- Acute Myeloid Leukemia (54 active studies)
- Advanced Solid Tumor (52 active studies)
- Colorectal Cancer (48 active studies)
- Ovarian Cancer (47 active studies)
- Prostate Cancer (45 active studies)
Leading research sponsors in Houston
- M.D. Anderson Cancer Center
- The University of Texas Health Science Center, Houston
- Baylor College of Medicine
- AstraZeneca
- The Methodist Hospital Research Institute
Frequently asked questions
How many paid clinical trials are currently recruiting in Houston?
There are approximately 3,048 recruiting clinical trials in Houston, Texas listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Houston pay participants?
Most recruiting trials in Houston compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Houston?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Houston?
The most common conditions under active study in Houston include Breast Cancer (77), Acute Myeloid Leukemia (54), Advanced Solid Tumor (52), Colorectal Cancer (48), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Houston?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Houston on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Houston?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Houston?
Recruiting research sites in Houston include MD Anderson Cancer Center, M D Anderson Cancer Center, Baylor College of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Houston right now?
The largest active categories in Houston are Cancer & tumors (1,179), Neurology & pain (139), Diabetes & metabolic (105). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.