Paid Clinical Trials in Iowa

Iowa has 819 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 16, 2026.

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819 clinical trials

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A Study to Evaluate the Risk of Tumor Lysis Syndrome (TLS) in Adult Participants Receiving Oral Venetoclax in Combination With Intravenously Infused Obinutuzumab or Oral Acalabrutinib for Previously Untreated Chronic Lymphocytic Leukemia (CLL)

for Chronic Lymphocytic Leukemia

Drug: Venetoclax

32 locations incl. Tucson

Sponsor: AbbVie

Sex: All·Age: 18+

Code: NCT06428019·Phase 3·Recruiting

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Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia

for Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

7 locations incl. Gilbert

Sponsor: MeiraGTx, LLC

Sex: All·Age: 18+

Code: NCT06544798·Phase 2·Enrolling By Invitation

Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

for Endothelial Function

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06499844·EARLY_Phase 1·Recruiting

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Real-time Personalized Brain State-dependent TMS After Stroke

for Stroke

1 location in Iowa City

Sponsor: Sara Hussain

Sex: All·Age: 18+

Code: NCT06533176·Recruiting

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Long-term Safety and Tolerability of BHV-7000

for Focal Epilepsy

Drug: BHV-7000

115 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 18 - 75

Code: NCT06443463·Phase 2·Enrolling By Invitation

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

for Peripheral Neuropathy

3 locations incl. San Francisco

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: All ages

Code: NCT06151600·Recruiting

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

for Advanced Lung Non-Small Cell Carcinoma

318 locations incl. Fayetteville

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 70+

Code: NCT06096844·Phase 3·Recruiting

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Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

for Diffuse Large B-Cell Lymphoma

Drug: Rituximab

14 locations incl. Berkeley

Sponsor: AstraZeneca

Sex: All·Age: 65 - 99

Code: NCT05952024·Phase 2·Recruiting

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Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer

for Metastatic Nasopharyngeal Carcinoma

Drug: Relatlimab

83 locations incl. Dublin

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06029270·Phase 2·Recruiting

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A Study of the Drug Letermovir as Prevention of Cytomegalovirus Infection After Stem Cell Transplant in Pediatric Patients

for Hematopoietic and Lymphoid Cell Neoplasm

29 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 2 - 18

Code: NCT05711667·Phase 3·Recruiting

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

50 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting

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Ivosidenib in Participants With Locally Advanced or Metastatic Conventional Chondrosarcoma Untreated or Previously Treated With 1 Systemic Treatment Regimen

for Locally Advanced or Metastatic Conventional Chondrosarcoma With an IDH1 Mutation, Untreated or Previously Treated With 1 Systemic Treatment Regimen

22 locations incl. Los Angeles

Sponsor: Servier Bio-Innovation LLC

Sex: All·Age: 18+

Code: NCT06127407·Phase 3·Recruiting

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Rigorous Evaluation of the READY to Stand Curriculum to Prevent the Commercial Sexual Exploitation of Children

for Sex Trafficking

1 location in Des Moines

Sponsor: University of Michigan

Sex: All·Age: 13 - 21·Accepts healthy volunteers

Code: NCT06587529·Recruiting

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From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

for Foot Injury

5 locations incl. San Diego

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65

Code: NCT06352788·Recruiting

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Dime La VerDAD: Verify, Debunk, and Disseminate

for Influenza

4 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06417762·Recruiting

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

117 locations incl. Goodyear

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting

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Behavioral Economic & Staffing Strategies in the ICU

for Implementation Science

3 locations incl. Iowa City

Sponsor: University of Nebraska

Sex: All·Age: 19+

Code: NCT06184945·Recruiting

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

13 locations incl. San Francisco

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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Paced Heart Rate Acceleration for Cardiac Conditioning

for Heart Failure, Systolic

1 location in Iowa City

Sponsor: Denice Hodgson-Zingman, MD

Sex: All·Age: 18 - 120

Code: NCT06332391·Recruiting

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ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

for Cardiovascular Risk

Drug: Ziltivekimab

208 locations incl. Alexander City

Sponsor: Novo Nordisk A/S

Sex: All·Age: 18+

Code: NCT06118281·Phase 3·Recruiting

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Adding Nivolumab to Usual Treatment for People With Advanced Stomach or Esophageal Cancer, PARAMUNE Trial

for Advanced Esophageal Adenocarcinoma

Drug: Nivolumab

372 locations incl. Little Rock

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06203600·Phase 2, Phase 3·Recruiting

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MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

for Acute Myeloid Leukemia

335 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05564390·Phase 2·Recruiting

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Essential Amino Acid Supplementation for Femoral Fragility Fractures

for Femoral Fracture

2 locations incl. Iowa City

Sponsor: Michael C Willey

Sex: All·Age: 65+

Code: NCT06050668·Phase 2·Recruiting

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A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

for Heart Failure

Drug: Empagliflozin

95 locations incl. Mobile

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06424288·Phase 3·Recruiting

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Cadisegliatin as Adjunctive Therapy to Insulin in Participants With Type 1 Diabetes

for Diabetes Mellitus, Type 1

60 locations incl. Scottsdale

Sponsor: vTv Therapeutics

Sex: All·Age: 18+

Code: NCT06334133·Phase 3·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

for Crohn's Disease

Drug: Tulisokibart

87 locations incl. Dothan

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 16 - 80

Code: NCT06430801·Phase 3·Recruiting

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Spastic Paraplegia - Centers of Excellence Research Network

for Hereditary Spastic Paraplegia

11 locations incl. Miami

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06553976·Recruiting

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Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

for Metastatic Breast Cancer

29 locations incl. Phoenix

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT06324357·Phase 1, Phase 2·Recruiting

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Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

for Myelofibrosis

Drug: Ruxolitinib

58 locations incl. Birmingham

Sponsor: Kartos Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06479135·Phase 3·Recruiting

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A Study to Customize Ibrutinib Treatment Regimens for Participants With Previously Untreated Chronic Lymphocytic Leukemia

for Leukemia, Lymphocytic, Chronic, B-Cell

Drug: Ibrutinib

32 locations incl. Cerritos

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05963074·Phase 2·Recruiting

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A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

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Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

11 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

135 locations incl. Birmingham

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting

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CSP #2026 - Beta Blocker Dialyzability on Cardiovascular Outcomes

for End-Stage Kidney Disease

8 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT05931276·Phase 3·Recruiting

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Neuronal and Network Mechanisms of Electrocortical Stimulation

for Epilepsy

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT06391294·Enrolling By Invitation

Treatment Targets in Spanish and English Bilingual Speech Intervention

for Speech Sound Disorder

1 location in Iowa City

Sponsor: Philip Combiths

Sex: All·Age: 3 - 8

Code: NCT06416306·Phase 1·Recruiting

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Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

for Malignant Female Reproductive System Neoplasm

186 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT06126276·Phase 2·Recruiting

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Preventing Injured Knees From osteoArthritis: Severity Outcomes

for Osteoarthritis, Knee

9 locations incl. Atlanta

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 45

Code: NCT06096259·Phase 2·Recruiting

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