Paid Clinical Trials in Iowa

Iowa has 761 paid clinical trials enrolling now across cities including Iowa City, Des Moines and Waukee. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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Healthy volunteers only

701 clinical trials

Project: Every Child for Younger Patients With Cancer

for Adrenal Gland Pheochromocytoma

Sites in Iowa City, Des Moines +231 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 25

Code: NCT02402244·Recruiting·Listed Mar 2015

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Frontline T-cell Engager vs Autologous Stem Cell Transplant (ASCT) and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma

for Multiple Myeloma, Newly Diagnosed

Sites in Iowa City +9 more locations

Sponsor: SCRI Development Innovations, LLC

Sex: All·Age: 19+

Code: NCT06974786·Phase 2·Recruiting·Listed May 2025

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Venetoclax in Children With Relapsed Acute Myeloid Leukemia (AML)

for Acute Myeloid Leukemia

Drug: Venetoclax

Sites in Iowa City +44 more locations

Sponsor: PedAL BCU, LLC

Sex: All·Age: 29 Days - 21

Code: NCT05183035·Phase 3·Recruiting·Listed Jan 2022

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

Sites in Iowa City, Des Moines +169 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting·Listed Mar 2020

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

Sites in Iowa City +70 more locations

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting·Listed May 2020

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Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

for Breast Carcinoma

Sites in Iowa City, Des Moines +462 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT06418204·Recruiting·Listed May 2024

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TSC Biosample Repository and Natural History Database

for Tuberous Sclerosis

Sites in Iowa City +22 more locations

Sponsor: National Tuberous Sclerosis Association

Sex: All·Age: All ages

Code: NCT05676099·Recruiting·Listed Jan 2023

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

Sites in Iowa City, Council Bluffs +471 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting·Listed Jan 2020

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The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

Sites in Iowa City +6 more locations

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting·Listed Apr 2021

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Thoracotomy Versus Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

for Metastatic Malignant Neoplasm in the Lung

Sites in Iowa City, Des Moines +209 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT05235165·Phase 3·Recruiting·Listed Feb 2022

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Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR

for Proliferative Diabetic Retinopathy (PDR)

Sites in West Des Moines +29 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT06790784·Phase 3·Recruiting·Listed Jan 2025

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

Sites in Des Moines +37 more locations

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting·Listed Jun 2018

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A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

for Stage I Mixed Cell Type Kidney Wilms Tumor

Sites in Iowa City, Des Moines +144 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT06401330·Phase 3·Recruiting·Listed May 2024

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Type 1 Diabetes Extension Study

for Type 1 Diabetes Mellitus

Sites in Iowa City +7 more locations

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: 8 - 35

Code: NCT02734277·Recruiting·Listed Apr 2016

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

Sites in Iowa City, Des Moines +132 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting·Listed Dec 2020

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Cybersickness Prevention and Mitigation in Virtual Reality for Healthy Volunteers

for Healthy Volunteers

Sites in Ames +1 more location

Sponsor: National Human Genome Research Institute (NHGRI)

Sex: All·Age: 18 - 60

Code: NCT06552754·Recruiting·Listed Aug 2024

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Role of ET-1, Physical Activity, and Sedentary Behavior in Microvascular Dysfunction Following GDM

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT06547619·EARLY_Phase 1·Recruiting·Listed Aug 2024

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Evaluation of Pirfenidone as a Novel Therapeutic Strategy Against Recurrent Acute Pancreatitis.

for Recurrent Acute Pancreatitis

Sites in Iowa City +2 more locations

Sponsor: University of Alabama at Birmingham

Sex: All·Age: 18 - 85

Code: NCT06253117·Phase 2·Recruiting·Listed Feb 2024

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Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05946785·EARLY_Phase 1·Recruiting·Listed Jul 2023

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Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

for Chondrosarcoma

Sites in Iowa City +3 more locations

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT04040205·Phase 2·Recruiting·Listed Jul 2019

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Intravitreal Faricimab Injections or Fluocinolone Acetonide (0.19 mg) Intravitreal Implants vs Observation for Prevention of VA Loss Due to Radiation Retinopathy

for Radiation Retinopathy

Sites in Iowa City +24 more locations

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18+

Code: NCT05844982·Phase 3·Recruiting·Listed May 2023

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

Sites in Iowa City +7 more locations

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting·Listed Dec 2018

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Harnessing Communication Preferences

for Intellectual Disability

Sites in Iowa City +1 more location

Sponsor: Joel E. Ringdahl

Sex: All·Age: 2 - 90

Code: NCT07278544·Recruiting·Listed Dec 2025

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Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

for Mechanical Ventilation Complication

Sites in Iowa City +1 more location

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT03901924·Recruiting·Listed Apr 2019

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Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

for Deep Venous Thrombosis

Sites in Iowa City +19 more locations

Sponsor: Yale University

Sex: All·Age: Up to 17

Code: NCT04924322·Phase 2, Phase 3·Recruiting·Listed Jun 2021

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PERceptions of Diltiazem Versus ADEnosine for Treatment of Supraventricular Tachycardia in the Emergency Department

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 100

Code: NCT07086560·Recruiting·Listed Jul 2025

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Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

for Recurrent Endometrial Carcinoma

Sites in Iowa City +10 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05950464·Phase 1·Recruiting·Listed Jul 2023

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Abemaciclib Dose Escalation to Maintain Intensity (ADE-MI)

for Breast Cancer

Sites in Iowa City +2 more locations

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT06169371·Phase 4·Recruiting·Listed Dec 2023

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

Sites in Iowa City +13 more locations

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting·Listed Sep 2021

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The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

for Atrial Fibrillation

Sites in Iowa City +86 more locations

Sponsor: Johns Hopkins University

Sex: All·Age: 22 - 85

Code: NCT05836987·Phase 3·Recruiting·Listed May 2023

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Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

for Extensive Stage Lung Small Cell Carcinoma

Sites in Des Moines, Waukee +144 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06769126·Phase 2·Recruiting·Listed Jan 2025

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Integrated Cancer Repository for Cancer Research

for Pancreatic Cancer

Sites in Council Bluffs, Waterloo +40 more locations

Sponsor: University of Nebraska

Sex: All·Age: 19 - 110·Accepts healthy volunteers

Code: NCT02012699·Recruiting·Listed Dec 2013

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Testing a Standardized Approach to Surgery and Chemotherapy for Type I Pleuropulmonary Blastoma or the Addition of an Anti-cancer Drug, Topotecan, to the Usual Treatment for Types II and III Pleuropulmonary Blastoma

for Pleuropulmonary Blastoma

Sites in Iowa City +75 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT06647953·Phase 3·Recruiting·Listed Oct 2024

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Paced Heart Rate Acceleration for Cardiac Conditioning

for Heart Failure, Systolic

1 location in Iowa City

Sponsor: Denice Hodgson-Zingman, MD

Sex: All·Age: 18 - 120

Code: NCT06332391·Recruiting·Listed Mar 2024

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Carbon Dioxide (CO2) Chemosensitivity and SUDEP

for Epilepsy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 99

Code: NCT04134754·Recruiting·Listed Oct 2019

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Neoadjuvant Weekly Paclitaxel and Biomarkers of Therapy Response

for Breast Neoplasm Female

Sites in Iowa City +1 more location

Sponsor: University of Wisconsin, Madison

Sex: Female·Age: 18+

Code: NCT03096418·Phase 4·Recruiting·Listed Mar 2017

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Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative Rhabdomyosarcoma

for Embryonal Rhabdomyosarcoma

Sites in Iowa City, Des Moines +161 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT05304585·Phase 3·Recruiting·Listed Mar 2022

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Single Arm Study of Neoadjuvant Dostarlimab in Stage II and III Deficient Mismatch Repair Colon Cancers

for Colon Cancer

Drug: Dostarlimab

Sites in Iowa City +1 more location

Sponsor: University of Iowa

Sex: All·Age: 18+

Code: NCT05239546·Phase 2·Recruiting·Listed Feb 2022

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Adenosine vs Diltiazem for Treatment of SVT in the ED

for Supraventricular Tachycardia (SVT)

1 location in Iowa City

Sponsor: Anne E. Zepeski

Sex: All·Age: 18 - 100

Code: NCT06993038·Phase 4·Recruiting·Listed May 2025

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Des Moines, Waukee +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

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