Paid Clinical Trials in Iowa

Iowa has 825 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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825 clinical trials

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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Immune Checkpoint Inhibitor Toxicity Risk Prediction in Solid Tumors

for Malignant Solid Neoplasm

843 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04871542·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

14 locations incl. Birmingham

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting

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A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

for Arthropathy of Knee

1 location in Iowa City

Sponsor: Nicolas Noiseux, MD, MS, FRCSC

Sex: All·Age: 18 - 100

Code: NCT04924205·Recruiting

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Study in Parkinson Disease of Exercise

for Parkinson Disease

24 locations incl. Birmingham

Sponsor: Northwestern University

Sex: All·Age: 40 - 80

Code: NCT04284436·Recruiting

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Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

10 locations incl. Little Rock

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting

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Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

for Lymphoma, Non-Hodgkin

12 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04996706·Enrolling By Invitation

Long-Term Follow-up of Subjects Who Were Treated With ST-920

for Fabry Disease

8 locations incl. Irvine

Sponsor: Sangamo Therapeutics

Sex: All·Age: 18+

Code: NCT05039866·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

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Mitral Valve Screening Survey

for Mitral Valve Disease

14 locations incl. Phoenix

Sponsor: Medstar Health Research Institute

Sex: All·Age: 18+

Code: NCT04736667·Recruiting

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

for C3G

Drug: Iptacopan

13 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT04817618·Phase 3·Recruiting

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Biorepository and Registry for Plasma Exchange Patients

for Antibody-mediated Rejection

1 location in Iowa City

Sponsor: Charles M Knudson

Sex: All·Age: 12 - 99

Code: NCT05004493·Recruiting

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Registry of Arthrex Hand and Wrist Products

for Ulnar/Radial Collateral Ligament Reconstruction

5 locations incl. Phoenix

Sponsor: Arthrex, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05046600·Recruiting

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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CureDuchenne Link®: A Resource for Research

for Duchenne Muscular Dystrophy

10 locations incl. Little Rock

Sponsor: CureDuchenne

Sex: All·Age: 4 Weeks+

Code: NCT04972604·Recruiting

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De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

for Stage I Breast Cancer

812 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 50 - 70

Code: NCT04852887·Phase 3·Recruiting

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APOLLO: A Randomized Phase II Double-Blind Study of Olaparib Versus Placebo Following Curative Intent Therapy in Patients With Resected Pancreatic Cancer and a Pathogenic BRCA1, BRCA2 or PALB2 Mutation

for Pancreatic Acinar Cell Carcinoma

Drug: Olaparib

451 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04858334·Phase 2·Recruiting

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Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability

for Metastatic Lung Small Cell Carcinoma

223 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04804644·Phase 3·Recruiting

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A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for Cervical Cancer

11 locations incl. Clovis

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT04895709·Phase 1, Phase 2·Recruiting

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Testing the Addition of Lenalidomide and Nivolumab to the Usual Treatment for Primary CNS Lymphoma

for Primary Diffuse Large B-Cell Lymphoma of the Central Nervous System

Drug: Nivolumab

54 locations incl. Los Angeles

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04609046·Phase 1·Recruiting

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An Internet-based Program to Help Cancer Survivors Manage Pain

for Cancer

149 locations incl. Fort Smith

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+

Code: NCT04462302·Recruiting

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Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine

for Acute Treatment of Migraine

Drug: Rimegepant

116 locations incl. Scottsdale

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04743141·Phase 3·Recruiting

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Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

for Recurrent Head and Neck Squamous Cell Carcinoma

178 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18 - 79

Code: NCT04671667·Phase 2·Recruiting

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Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer

Drug: Durvalumab

5 locations incl. Chicago

Sponsor: Muhammad Furqan

Sex: All·Age: 18+

Code: NCT04699838·Phase 2·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial

for Metastatic Clear Cell Renal Cell Carcinoma

387 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04510597·Phase 3·Recruiting

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Fenofibrate for Prevention of DR Worsening

for Diabetic Retinopathy

66 locations incl. Glendale

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 18 - 80

Code: NCT04661358·Phase 3·Recruiting

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

31 locations incl. Phoenix

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting

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Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

10 locations incl. Iowa City

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting

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Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

620 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting

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Adjuvant Effect of Physical Exercise on Immune Response to COVID-19 Vaccination and Interactions With Stress

for Immunization

1 location in Ames

Sponsor: Iowa State University

Sex: All·Age: 18 - 64·Accepts healthy volunteers

Code: NCT05213000·Recruiting

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Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

for Plasma Cell Myeloma

642 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT04566328·Phase 3·Recruiting

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Single-Sided Deafness and Asymmetric Hearing Loss

for Hearing Loss, Unilateral

5 locations incl. Chicago

Sponsor: Med-El Corporation

Sex: All·Age: 5+

Code: NCT04506853·Recruiting

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Study to Test OBI-3424 in Patients With T-Cell Acute Lymphoblastic Leukemia (T-ALL) or T-Cell Lymphoblastic Lymphoma (T-LBL)

for Recurrent T Acute Lymphoblastic Leukemia

163 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 12+

Code: NCT04315324·Phase 1, Phase 2·Recruiting

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ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

for Acute Respiratory Distress Syndrome

76 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 14 Days - 20

Code: NCT05388708·Recruiting

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Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

18 locations incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting

Apply to this trial