Paid Clinical Trials in Iowa

Iowa has 825 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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825 clinical trials

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The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

10 locations incl. San Diego

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting

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Randomized Study in Children and Adolescents With Migraine: Acute Treatment

for Pediatric Migraine

169 locations incl. Birmingham

Sponsor: Pfizer

Sex: All·Age: 6 - 17

Code: NCT04649242·Phase 3·Recruiting

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Testing the Addition of Radiation Therapy to the Usual Immune Therapy Treatment (Atezolizumab) for Extensive Stage Small Cell Lung Cancer, The RAPTOR Trial

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

416 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04402788·Phase 2, Phase 3·Recruiting

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A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

for Acral Lentiginous Melanoma

Drug: Ipilimumab

331 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04511013·Phase 2·Recruiting

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Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

for Advanced Lung Non-Squamous Non-Small Cell Carcinoma

Drug: Bevacizumab

603 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04181060·Phase 3·Recruiting

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A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

for Advanced Solid Tumors

Drug: Cemiplimab

21 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04626635·Phase 1, Phase 2·Recruiting

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

54 locations incl. Birmingham

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

209 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting

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Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

for FSHD

16 locations incl. Los Angeles

Sponsor: University of Kansas Medical Center

Sex: All·Age: All ages

Code: NCT04635891·Recruiting

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A Randomized Trial to Evaluate Sequential vs Simultaneous Patching

for Amblyopia

68 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 3 - 13

Code: NCT04378790·Phase 3·Recruiting

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ConTTRibute: A Global Observational Study of Patients With Transthyretin (TTR)-Mediated Amyloidosis (ATTR Amyloidosis)

for Transthyretin-Mediated Amyloidosis

13 locations incl. La Jolla

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: All ages

Code: NCT04561518·Recruiting

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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

for Cystic Fibrosis

35 locations incl. Birmingham

Sponsor: Sonya Heltshe

Sex: All·Age: Up to 10

Code: NCT04509050·Recruiting

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MMP-9 Inhibition for Recalcitrant Wet AMD

for Exudative Macular Degeneration

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 50 - 99

Code: NCT04504123·Phase 2·Recruiting

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University of Iowa Interventional Psychiatry Service Patient Registry

for Treatment Resistant Depression

1 location in Iowa City

Sponsor: Mark Niciu

Sex: All·Age: 18 - 99

Code: NCT04480918·Recruiting

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A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

for Anaplastic Kidney Wilms Tumor

177 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 30

Code: NCT04322318·Phase 2·Recruiting

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Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

for Biochemically Recurrent Prostate Carcinoma

Drug: Apalutamide

342 locations incl. Anchorage

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: Male·Age: 18+

Code: NCT04423211·Phase 3·Recruiting

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Ferritin and Iron Burden in SAH sIRB

for SAH

2 locations incl. Iowa City

Sponsor: Duke University

Sex: All·Age: 18 - 75

Code: NCT03754725·Phase 1, Phase 2·Recruiting

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ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders

for Hematologic Disorder

71 locations incl. Phoenix

Sponsor: American Thrombosis and Hemostasis Network

Sex: All·Age: All ages

Code: NCT04398628·Recruiting

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A Stepped Care Approach to Treating Tobacco Use in Rural Veterans

for Tobacco Cessation

1 location in Iowa City

Sponsor: Iowa City Veterans Affairs Medical Center

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT04501016·Phase 2, Phase 3·Not Yet Recruiting

A Phase 1/2, Open-label, Safety and Dosing Study of Autologous CART Cells (Desmoglein 3 Chimeric Autoantibody Receptor T Cells [DSG3-CAART] or CD19-specific Chimeric Antigen Receptor T Cells [CABA-201]) in Subjects With Active, Pemphigus Vulgaris (RESET-PV)

for Pemphigus Vulgaris

13 locations incl. Redwood City

Sponsor: Cabaletta Bio

Sex: All·Age: 18+

Code: NCT04422912·Phase 1, Phase 2·Recruiting

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Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

for Buccal Mucosa Squamous Cell Carcinoma

105 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT04333537·Phase 2, Phase 3·Recruiting

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A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

for Ovarian Carcinoma

539 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: Female·Age: 35 - 50

Code: NCT04251052·Recruiting

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Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

for Cognitive Impairment, Mild

102 locations incl. Birmingham

Sponsor: Duke University

Sex: All·Age: 75+·Accepts healthy volunteers

Code: NCT04262206·Phase 4·Recruiting

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Hydrus® Microstent New Enrollment Post-Approval Study

for Primary Open Angle Glaucoma

22 locations incl. Irvine

Sponsor: Alcon Research

Sex: All·Age: 45+

Code: NCT04553523·Recruiting

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Patisiran-Lipid Nanoparticle (LNP) Pregnancy Surveillance Program

for Hereditary Transthyretin-mediated (hATTR) Amyloidosis

1 location in Iowa City

Sponsor: Alnylam Pharmaceuticals

Sex: Female·Age: All ages

Code: NCT05040373·Recruiting

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A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations

for Acute Myeloid Leukemia

185 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 21

Code: NCT04293562·Phase 3·Recruiting

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Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

for Pancreatic Neoplasm

408 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 50 - 75

Code: NCT04239573·Recruiting

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

1149 locations incl. Anchorage

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting

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HEALEY ALS Platform Trial - Master Protocol

for Amyotrophic Lateral Sclerosis

81 locations incl. Phoenix

Sponsor: Merit E. Cudkowicz, MD

Sex: All·Age: 18+

Code: NCT04297683·Phase 2, Phase 3·Recruiting

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Antibiotic Prophylaxis in High-Risk Arthroplasty Patients

for Infections Joint Prosthetic

2 locations incl. Iowa City

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 99

Code: NCT04297592·Phase 4·Enrolling By Invitation

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

for Acute Stroke

1 location in Iowa City

Sponsor: Enrique Leira

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03481205·Recruiting

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Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for Metastatic Small Intestinal Adenocarcinoma

536 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04205968·Phase 2·Recruiting

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Adjuvant Pembrolizumab vs Observation Following Curative Resection for Stage I Non-small Cell Lung Cancer (NSCLC) With Primary Tumors Between 1-4 cm

for NSCLC, Stage I

13 locations incl. Tampa

Sponsor: Greg Durm, MD

Sex: All·Age: 18+

Code: NCT04317534·Phase 2·Recruiting

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Testing the Addition of the Drug Apalutamide to the Usual Hormone Therapy and Radiation Therapy After Surgery for Prostate Cancer, INNOVATE Trial

for Prostate Adenocarcinoma

Drug: Apalutamide

345 locations incl. Phoenix

Sponsor: NRG Oncology

Sex: Male·Age: 18+

Code: NCT04134260·Phase 3·Recruiting

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Collection of Research Data and Samples From Patients Who Experience Immunotherapy Side Effects

for Malignancy

626 locations incl. Anchorage

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: All ages

Code: NCT04242095·Recruiting

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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

for Coronavirus Infection (COVID-19)

49 locations incl. Phoenix

Sponsor: Duke University

Sex: All·Age: 0 - 20·Accepts healthy volunteers

Code: NCT04278404·Recruiting

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A Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

for Low Grade Astrocytoma

Drug: Selumetinib

124 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 2 - 21

Code: NCT04166409·Phase 3·Recruiting

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Anticoagulation in ICH Survivors for Stroke Prevention and Recovery

for Intracerebral Hemorrhage

187 locations incl. Birmingham

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT03907046·Phase 3·Recruiting

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The Heartland Study

for Pregnancy Related

4 locations incl. Indianapolis

Sponsor: Heartland Health Research Alliance

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT05492708·Recruiting

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Carbon Dioxide (CO2) Chemosensitivity and SUDEP

for Epilepsy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 99

Code: NCT04134754·Recruiting

Apply to this trial