Paid Clinical Trials in Iowa

Iowa has 825 paid clinical trials enrolling now across cities including Iowa City, Des Moines and West Des Moines. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 18, 2026.

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825 clinical trials

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Edwards PASCAL Transcatheter Valve Repair System Pivotal Clinical Trial

for Tricuspid Regurgitation

73 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: 18+

Code: NCT04097145·Recruiting

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Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)

for Generalized Myasthenia Gravis

32 locations incl. Birmingham

Sponsor: Alexion Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT04202341·Recruiting

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Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)

for Vertebral Artery Stenosis

10 locations incl. Jacksonville

Sponsor: St. Louis University

Sex: All·Age: 18 - 90

Code: NCT03999983·Recruiting

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Measurement of Bladder Pressure With a Novel External Device (Cystomanometer) - Home Use

for Urinary Bladder, Neurogenic

1 location in Iowa City

Sponsor: Christopher Cooper

Sex: All·Age: 1 - 99

Code: NCT04128709·Recruiting

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Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

for Mild Cognitive Impairment

1 location in Iowa City

Sponsor: Natalie Denburg

Sex: All·Age: 56 - 85·Accepts healthy volunteers

Code: NCT03954899·Recruiting

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The Effects of AFO Heel Height and Stiffness on Gait

for Musculoskeletal Injury

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 70

Code: NCT04800484·Recruiting

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A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

for Acute Myeloid Leukemia

Drug: Revumenib

22 locations incl. Duarte

Sponsor: Syndax Pharmaceuticals

Sex: All·Age: 30 Days+

Code: NCT04065399·Phase 1, Phase 2·Recruiting

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Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

for B Acute Lymphoblastic Leukemia

203 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 365 Days - 25

Code: NCT03959085·Phase 3·Recruiting

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Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

for Chondrosarcoma

4 locations incl. Jacksonville

Sponsor: Medical College of Wisconsin

Sex: All·Age: 18+

Code: NCT04040205·Phase 2·Recruiting

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Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

for C3 Glomerulopathy

Drug: Iptacopan

5 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 100

Code: NCT03955445·Phase 3·Recruiting

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A Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension

for PAH

Drug: Ralinepag

48 locations incl. Phoenix

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT03683186·Phase 3·Enrolling By Invitation

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

for Colorectal Cancer

146 locations incl. Millville

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 60+

Code: NCT03998202·Recruiting

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Stroke Thrombectomy and Aneurysm Registry

for Stroke

54 locations incl. Birmingham

Sponsor: Medical University of South Carolina

Sex: All·Age: 1 - 120

Code: NCT04994756·Recruiting

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Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma

for Smoldering Plasma Cell Myeloma

Drug: Daratumumab

741 locations incl. Birmingham

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03937635·Phase 3·Recruiting

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Naive T Cell Depletion for Preventing Chronic Graft-versus-Host Disease in Children and Young Adults With Blood Cancers Undergoing Donor Stem Cell Transplant

for Acute Biphenotypic Leukemia

10 locations incl. Los Angeles

Sponsor: Fred Hutchinson Cancer Center

Sex: All·Age: 6 Months - 26·Accepts healthy volunteers

Code: NCT03779854·Phase 2·Recruiting

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GORE® CARDIOFORM Septal Occluder and Antiplatelet Medical Management for Reduction of Recurrent Stroke in Patients With Patent Foramen Ovale (PFO): the REDUCE Post Approval Study

for Stroke

45 locations incl. Tucson

Sponsor: W.L.Gore & Associates

Sex: All·Age: 18 - 70

Code: NCT03821129·Recruiting

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Safety and Preliminary Efficacy of OBT076 in Recurrent/Metastatic CD205+ Solid Tumors

for Solid Tumor

10 locations incl. Phoenix

Sponsor: Oxford BioTherapeutics Ltd

Sex: All·Age: 18+

Code: NCT04064359·Phase 1·Recruiting

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TMS - Intracranial Electrodes

for Epilepsy Intractable

1 location in Iowa City

Sponsor: Aaron Boes

Sex: All·Age: 18+

Code: NCT03702127·Enrolling By Invitation

Objectively Diagnose and Monitor Treatment of Light Sensitivity

for Photophobia

1 location in Iowa City

Sponsor: Randy Kardon

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03694626·Recruiting

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Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions

for Metastatic Uveal Melanoma

12 locations incl. Los Angeles

Sponsor: IDEAYA Biosciences

Sex: All·Age: 18+

Code: NCT03947385·Phase 1, Phase 2·Recruiting

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Androgen Deprivation Therapy (ADT) and Pembrolizumab for Advanced Stage Androgen Receptor-positive Salivary Gland Carcinoma

for Salivary Gland Carcinoma

7 locations incl. Chicago

Sponsor: Manish Patel

Sex: All·Age: 18+

Code: NCT03942653·Phase 2·Recruiting

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Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

for Lower Respiratory Tract Infection

49 locations incl. Duarte

Sponsor: Ansun Biopharma, Inc.

Sex: All·Age: All ages

Code: NCT03808922·Phase 3·Recruiting

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Sleep Apnea in Patients With MGUS and MM

for Multiple Myeloma

1 location in Iowa City

Sponsor: Michael Tomasson

Sex: All·Age: 18 - 99

Code: NCT04114084·Recruiting

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Activity Levels in Bone Marrow Transplant Patients

for Bone Marrow Transplant

1 location in Iowa City

Sponsor: Michael Tomasson

Sex: All·Age: 18 - 99

Code: NCT04115241·Recruiting

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Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

for Bladder Adenocarcinoma

Drug: Cabozantinib

577 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT03866382·Phase 2·Recruiting

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New Non-invasive Modalities for Assessing Retinal Structure and Function

for Ischemic Optic Neuropathy

1 location in Iowa City

Sponsor: Randy Kardon

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT03475173·Recruiting

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Cell Free DNA in Cardiac Sarcoidosis

for Sarcoidosis With Myocarditis

2 locations incl. Iowa City

Sponsor: Nabeel Hamzeh

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT03858777·Recruiting

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Antibiotic Irrigations for Intra-Abdominal Drains

for Abdominal Abscess

1 location in Iowa City

Sponsor: Paolo Goffredo

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03476941·Phase 2·Recruiting

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Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery

for Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7

140 locations incl. Tucson

Sponsor: ECOG-ACRIN Cancer Research Group

Sex: All·Age: 18+

Code: NCT03493425·Phase 2·Recruiting

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Volume Support/Assist Control Mode Ventilation and Diaphragmatic Atrophy

for Mechanical Ventilation Complication

2 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT03901924·Recruiting

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Two Dose Levels of Privigen in Pediatric CIDP

for Pediatric Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

9 locations incl. Phoenix

Sponsor: CSL Behring

Sex: All·Age: 2 - 17

Code: NCT03684018·Phase 4·Recruiting

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Oxytocin and Fetal Heart Rate Changes

for Fetal Bradycardia Complicating Labor and Delivery

2 locations incl. Iowa City

Sponsor: Unyime Ituk

Sex: Female·Age: 18 - 55·Accepts healthy volunteers

Code: NCT03232918·Phase 4·Recruiting

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Lung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer

for Previously Treated Non-Small Cell Lung Cancer

1229 locations incl. Birmingham

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03851445·Phase 2, Phase 3·Recruiting

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A Long-term Observational Study Evaluating Eteplirsen, Golodirsen, or Casimersen in Routine Clinical Practice

for Duchenne Muscular Dystrophy

20 locations incl. Little Rock

Sponsor: Sarepta Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06606340·Enrolling By Invitation

Estab Biomarkers and Clinical Endpoints in Myotonic Dystrophy Type 1 (END-DM1)

for Myotonic Dystrophy 1

10 locations incl. La Jolla

Sponsor: Virginia Commonwealth University

Sex: All·Age: 18 - 70

Code: NCT03981575·Recruiting

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Multisite Inventory of Neonatal-Perinatal Interventions (MINI) Minimum Dataset

for Infant, Extremely Premature

37 locations incl. Birmingham

Sponsor: The University of Texas Health Science Center, Houston

Sex: All·Age: 0 - 1

Code: NCT05685745·Recruiting

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Stereotactic Radiosurgery Compared With Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) Plus Memantine for 5 or More Brain Metastases

for Brain Metastases

73 locations incl. Tucson

Sponsor: Canadian Cancer Trials Group

Sex: All·Age: 18+

Code: NCT03550391·Phase 3·Recruiting

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Regional Radiotherapy in Biomarker Low-Risk Node Positive and T3N0 Breast Cancer

for Breast Cancer

451 locations incl. Fairbanks

Sponsor: Canadian Cancer Trials Group

Sex: Female·Age: 35+

Code: NCT03488693·Phase 3·Recruiting

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Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants

for Lactating Women on Select DOI

20 locations incl. La Jolla

Sponsor: Duke University

Sex: All·Age: All ages

Code: NCT03511118·Recruiting

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Stimulant Effects on Disruptive Behavior

for Attention Deficit Hyperactivity Disorder

1 location in Iowa City

Sponsor: Matthew J O'Brien, PhD, BCBA-D

Sex: All·Age: 48 Months - 12·Accepts healthy volunteers

Code: NCT03420339·Phase 4·Recruiting

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