Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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2,519 clinical trials

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Personalized Autologous Transplant for Multiple Myeloma

for Multiple Myeloma

Sites in Chicago +1 more location

Sponsor: Emory University

Sex: All·Age: 18+

Code: NCT04483206·Phase 1·Recruiting·Listed Jul 2020

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The Radiation Oncology-Biology Integration Network (ROBIN) Molecular Characterization Trial (MCT) of Standard Short Course Radiotherapy for Rectal Cancer

for Rectal Cancer

Sites in Chicago +4 more locations

Sponsor: Weill Medical College of Cornell University

Sex: All·Age: 18 - 90

Code: NCT05943210·Recruiting·Listed Jul 2023

Apply to this trial

Trial-Ready Cohort-Down Syndrome (TRC-DS)

for Down Syndrome

Sites in Park Ridge +17 more locations

Sponsor: University of Southern California

Sex: All·Age: 25 - 55

Code: NCT04165109·Recruiting·Listed Nov 2019

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Evaluating the Communication Between Patients and Providers in Cancer Clinics

for Cancer

Sites in Chicago +2 more locations

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 18+

Code: NCT06985953·Recruiting·Listed May 2025

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STM-06: POLARIS-POlymetastic Lesion Ablative Radiotherapy With Immunotherapy Study

for Advanced Solid Tumor

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT07269080·Phase 1·Recruiting·Listed Dec 2025

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Safety Study of Unlicensed IND Cord Blood Units Manufactured by the National Cord Blood Program for Unrelated Transplantation

for Infusion Reactions

Sites in Chicago +59 more locations

Sponsor: New York Blood Center

Sex: All·Age: All ages

Code: NCT01656603·Phase 2·Recruiting·Listed Aug 2012

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Pemetrexed Response in Relation to Tumor Alterations of Gene Status for the Treatment of Patients With Metastatic Urothelial Bladder Cancer and Other Solid Tumors

for Metastatic Bladder Urothelial Carcinoma

Sites in Chicago & Orland Park

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06630416·Phase 2·Recruiting·Listed Oct 2024

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Novel Visual Education Tool to Improve Recognition and Reporting of Postpartum Urgent Maternal Warning Signs

for Postpartum

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18+

Code: NCT06912776·Recruiting·Listed Apr 2025

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Study of Individuals Affected With Hypoplasminogenemia

for Plasminogen Deficiency

Sites in Chicago +10 more locations

Sponsor: Indiana Hemophilia &Thrombosis Center, Inc.

Sex: All·Age: All ages

Code: NCT03797495·Recruiting·Listed Jan 2019

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Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy

for Pediatric Patients Treated With Radiation Therapy

Sites in Warrenville +22 more locations

Sponsor: Massachusetts General Hospital

Sex: All·Age: Up to 21

Code: NCT01696721·Recruiting·Listed Oct 2012

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Pupillometry in Delayed Sleep Wake Phase Disorder

for Delayed Sleep-Wake Phase Disorder

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 16+

Code: NCT06949644·Recruiting·Listed Apr 2025

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Pancreatic Enzyme Replacement Therapy for Acute Pancreatitis-Associated Exocrine Pancreatic Insufficiency

for Exocrine Pancreatic Insufficiency

Sites in Chicago +4 more locations

Sponsor: Ohio State University

Sex: All·Age: 18+

Code: NCT06477159·Phase 4·Recruiting·Listed Jun 2024

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NEPTUNE Match Study

for Nephrotic Syndrome in Children

Sites in Chicago +15 more locations

Sponsor: University of Michigan

Sex: All·Age: 1 - 80

Code: NCT04571658·Recruiting·Listed Oct 2020

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A Study of the Natural Progression of Interstitial Lung Disease (ILD)

for Interstitial Lung Diseases

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT00470327·Recruiting·Listed May 2007

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Intrathecal Morphine for Analgesia in Video-assisted and Robotic-assisted Thoracic Surgery

for Pain, Postoperative

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT05351229·Phase 4·Recruiting·Listed Apr 2022

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J-Tip Use for Paracentesis in Adults With Ascites

for Evaluate Patient Comfort Level During Paracentesis by Numbing Skin With a Needle-less Device, Instead of Using a Needle to Numb the Skin

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06996379·Recruiting·Listed May 2025

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Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

for Graft Vs Host Disease

Sites in Chicago +3 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: 2+

Code: NCT04380740·Phase 2·Recruiting·Listed May 2020

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CLOZAPINE Response in Biotype-1

for Schizophrenia

Sites in Chicago +4 more locations

Sponsor: University of Texas Southwestern Medical Center

Sex: All·Age: 18 - 60

Code: NCT04580134·Phase 4·Recruiting·Listed Oct 2020

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Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence

for Stress Urinary Incontinence

Sites in Chicago +6 more locations

Sponsor: NICHD Pelvic Floor Disorders Network

Sex: Female·Age: 21+

Code: NCT06480227·Recruiting·Listed Jun 2024

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Genomic Predictors of Recurrent Pregnancy Loss

for Recurrent Pregnancy Loss

Sites in Chicago +8 more locations

Sponsor: Yale University

Sex: All·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05444283·Recruiting·Listed Jul 2022

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IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

for Type B Aortic Dissection

Sites in Chicago, Springfield +50 more locations

Sponsor: Duke University

Sex: All·Age: 21+

Code: NCT06087029·Recruiting·Listed Oct 2023

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Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Chicago, Peoria +913 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05929768·Phase 3·Recruiting·Listed Jul 2023

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A Registry for People With T-cell Lymphoma

for T-cell Lymphoma

Sites in Chicago +25 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: All ages

Code: NCT05978141·Recruiting·Listed Aug 2023

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Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

for Lymphoblastic Leukemia

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18+

Code: NCT04747912·Phase 2·Recruiting·Listed Feb 2021

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Sickle Cell Clinical Research and Intervention Program

for Sickle Cell Disease

Sites in Peoria +4 more locations

Sponsor: St. Jude Children's Research Hospital

Sex: All·Age: All ages

Code: NCT02098863·Recruiting·Listed Mar 2014

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Exercise Training for Managing Major Depressive Disorder in Multiple Sclerosis

for Multiple Sclerosis

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18 - 64

Code: NCT05051618·Recruiting·Listed Sep 2021

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Gut Microbiota-Mediated Inflammatory Interactions Between AUD and HIV Infection

for Alcohol Use Disorder

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 45 - 75·Accepts healthy volunteers

Code: NCT06139224·Recruiting·Listed Nov 2023

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Late Onset Alzheimer's Disease

for Alzheimer Disease

Sites in Aurora +11 more locations

Sponsor: Columbia University

Sex: All·Age: 55+·Accepts healthy volunteers

Code: NCT05010603·Recruiting·Listed Aug 2021

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A Phase I Feasibility Study of an Intracortical Visual Prosthesis (ICVP) for People With Blindness

for Ocular Injury

1 location in Chicago

Sponsor: Illinois Institute of Technology

Sex: All·Age: 19 - 70

Code: NCT04634383·Recruiting·Listed Nov 2020

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Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

for Pediatric Cancer

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: All ages

Code: NCT05120518·Recruiting·Listed Nov 2021

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Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors

for Metastatic Malignant Neoplasm in the Liver

Sites in Chicago, Urbana +378 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT05040360·Phase 2·Recruiting·Listed Sep 2021

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Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial

for Prostate Adenocarcinoma

Drug: Relugolix

1 location in Chicago

Sponsor: Sean Sachdev

Sex: Male·Age: 18+

Code: NCT06499870·Phase 2·Recruiting·Listed Jul 2024

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Education & Mentorship of Advanced Practice Providers to Increase Community-based Research Within the NCORP Network, COACH-APP Trial

for Other

Sites in Peoria, Bloomington +29 more locations

Sponsor: Wake Forest University Health Sciences

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06904391·Recruiting·Listed Apr 2025

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The Gut and Skin Microbiome in Vitiligo Disease Progression

for Vitiligo

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 89·Accepts healthy volunteers

Code: NCT03577327·Recruiting·Listed Jul 2018

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Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections

for Gonorrhea

Sites in Chicago +12 more locations

Sponsor: Westat

Sex: Female·Age: 13 - 29

Code: NCT06738407·Phase 4·Recruiting·Listed Dec 2024

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Lanreotide Versus Placebo Before Surgery to Prevent a Surgical Complication Called a Pancreatic Fistula

for Pancreatic Carcinoma

Sites in Chicago +17 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06807437·Phase 3·Recruiting·Listed Feb 2025

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Evaluating The Efficacy Of Combined Cognitive Processing Therapy and Stellate Ganglion Blocks for PTSD

for PTSD

1 location in Chicago

Sponsor: Rush University Medical Center

Sex: All·Age: 18+

Code: NCT06570213·EARLY_Phase 1·Recruiting·Listed Aug 2024

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Adaptive Mechanisms Responsible for Weight Change in Youth With Obesity

for Childhood Obesity

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 11 - 15

Code: NCT05125822·Recruiting·Listed Nov 2021

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Comparing Dara-VCD Chemotherapy Plus Stem Cell Transplant to Dara-VCD Chemotherapy Alone for People Who Have Newly Diagnosed AL Amyloidosis

for AL Amyloidosis

Sites in Chicago, Urbana +114 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06022939·Phase 3·Recruiting·Listed Sep 2023

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A Study of Daratumumab and Dose-Adjusted EPOCH in Plasmablastic Lymphoma

for Plasmablastic Lymphoma

Drug: Daratumumab

Sites in Chicago +7 more locations

Sponsor: AIDS Malignancy Consortium

Sex: All·Age: 18+

Code: NCT04139304·EARLY_Phase 1·Recruiting·Listed Oct 2019

Apply to this trial