Paid Clinical Trials in Illinois

Illinois has 2,847 paid clinical trials enrolling now across cities including Chicago, Peoria and Evanston. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Illinois include Northwestern Medicine, University of Chicago Medicine and Rush, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

Filter results

Filter results

State

City

Recruitment status

Phase

Study type

Intervention

Condition

Sex

Age

Healthy volunteers only

2,519 clinical trials

Get a weekly email when new trials open in Chicago, IL.

Renal Mass Biopsy, PEER, and 99mTc-sestamibi SPECT/CT for Patients With Clinically Localized Renal Tumors

for Kidney Tumor

1 location in Maywood

Sponsor: Loyola University

Sex: All·Age: 18+

Code: NCT05728957·Recruiting·Listed Feb 2023

Apply to this trial

Powered Prosthesis for Use With TF Osseointegration Recipients

for Amputation

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 70

Code: NCT06160882·Recruiting·Listed Dec 2023

Apply to this trial

The Dragon PLC Trial (DRAGON-PLC)

for Primary Liver Cancer

Sites in Chicago +4 more locations

Sponsor: Maastricht University

Sex: All·Age: 18+

Code: NCT06914648·Recruiting·Listed Apr 2025

Apply to this trial

Blood Pressure Variability and Ischemic Stroke Outcome

for Acute Ischemic Stroke

Sites in Chicago +2 more locations

Sponsor: Yale University

Sex: All·Age: 18+

Code: NCT05756257·Recruiting·Listed Mar 2023

Apply to this trial

Specimen and Data Study for Ovarian Cancer Early Detection and Prevention

for Cervical Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18 - 80·Accepts healthy volunteers

Code: NCT00005095·Recruiting·Listed Jan 2003

Apply to this trial

TREAT-BE Study (Treatment With Resection and Endoscopic Ablation Techniques for Barrett's Esophagus)

for Barrett's Esophagus

Sites in Chicago +3 more locations

Sponsor: University of Colorado, Denver

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT02634645·Recruiting·Listed Dec 2015

Apply to this trial

Simple Bone Cysts in Kids

for Bone Cyst

Sites in Chicago +3 more locations

Sponsor: The Hospital for Sick Children

Sex: All·Age: 2 - 21

Code: NCT02193841·Phase 3·Recruiting·Listed Jul 2014

Apply to this trial

Delivery Room Intervention and Evaluation Network

for Resuscitation

1 location in Itasca

Sponsor: American Academy of Pediatrics

Sex: All·Age: 0 Days - 1 Day

Code: NCT06803498·Recruiting·Listed Jan 2025

Apply to this trial

R01.Aim 2.Study 1: IsoReach

for Stroke

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06656754·EARLY_Phase 1·Recruiting·Listed Oct 2024

Apply to this trial

Lynch Syndrome Integrative Epidemiology and Genetics

for Lynch Syndrome

Sites in Chicago +1 more location

Sponsor: University of Colorado, Denver

Sex: All·Age: 18+

Code: NCT06582914·Recruiting·Listed Sep 2024

Apply to this trial

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

for Osteosarcoma

1 location in Chicago

Sponsor: Ann & Robert H Lurie Children's Hospital of Chicago

Sex: All·Age: 6 - 17

Code: NCT06235125·Phase 1·Recruiting·Listed Jan 2024

Apply to this trial

Noninvasive Brain Stimulation in Adult Amblyopia

for Amblyopia

1 location in Downers Grove

Sponsor: Midwestern University

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06712849·Recruiting·Listed Dec 2024

Apply to this trial

Ivosidenib Plus Durvalumab and Gemcitabine/Cisplatin as First-Line Therapy in Participants With Locally Advanced or Metastatic Cholangiocarcinoma With an IDH1 Mutation

for Locally Advanced, Unresectable or Metastatic Cholangiocarcinoma With an IDH1 Mutation

Drug: Durvalumab

Sites in Chicago +7 more locations

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06501625·Phase 1, Phase 2·Recruiting·Listed Jul 2024

Apply to this trial

Improving Adherence to Spinal Cord Injury Exercise Guidelines Using Smartphone Technology and E-coaching

for Spinal Cord Injuries

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 80

Code: NCT05424172·Recruiting·Listed Jun 2022

Apply to this trial

DREAM: Double Lung Transplant REgistry Aimed for Lung-limited Malignancies

for Lung Cancer

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 75

Code: NCT05671887·Recruiting·Listed Jan 2023

Apply to this trial

Comparison of Two Sedation Regimens for Awake Fiberoptic Intubation

for Awake Fiberoptic Intubation

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 18+

Code: NCT05736198·Recruiting·Listed Feb 2023

Apply to this trial

Non-invasive Brain Stimulation for Treating Symptomatic Convergence Insufficiency

for Convergence Insufficiency

1 location in Downers Grove

Sponsor: Midwestern University

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT05877560·Recruiting·Listed May 2023

Apply to this trial

Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)

for Cognitive Change

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 45 - 64·Accepts healthy volunteers

Code: NCT06605898·Recruiting·Listed Sep 2024

Apply to this trial

Antibiotics for Delirium in Older Adults With No Clear Urinary Tract Infection

for Infectious Disease

1 location in Chicago

Sponsor: Mount Sinai Hospital, Canada

Sex: All·Age: 60+

Code: NCT06004739·Recruiting·Listed Aug 2023

Apply to this trial

MANAGE-VT Registry - MANAGEment of Ventricular Tachycardia Outcomes Registry

for Ventricular Tachycardia

1 location in Chicago

Sponsor: CorVita Science Foundation

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06455488·Recruiting·Listed Jun 2024

Apply to this trial

Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy

for Cerebral Palsy

Sites in Chicago +3 more locations

Sponsor: University of California, Los Angeles

Sex: All·Age: Up to 18

Code: NCT06189781·Phase 4·Recruiting·Listed Jan 2024

Apply to this trial

Understanding How Powered Componentry Impacts K2-Level Transfemoral Amputee Gait

for Amputation

1 location in Chicago

Sponsor: Shirley Ryan AbilityLab

Sex: All·Age: 18 - 95

Code: NCT06433648·Recruiting·Listed May 2024

Apply to this trial

Prostate Single Port & Laser Enucleation Comparison Trial

for Prostate Hyperplasia

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: Male·Age: 18 - 88

Code: NCT06224218·Recruiting·Listed Jan 2024

Apply to this trial

Plants Optimizing Development Study (PODS)

for Healthy Children

1 location in Urbana

Sponsor: University of Illinois at Urbana-Champaign

Sex: All·Age: 8 - 11·Accepts healthy volunteers

Code: NCT06276426·Recruiting·Listed Feb 2024

Apply to this trial

VR and Cooled Genicular Nerve Radio Frequency Ablation for Chronic Knee Pain

for Pain, Chronic

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT06336447·Recruiting·Listed Mar 2024

Apply to this trial

Decitabine and Selinexor in Combination to Reverse Drug Resistance With Standard Chemotherapy in Ovarian Cancer

for Ovarian Cancer

Drug: Selinexor

1 location in Maywood

Sponsor: Loyola University

Sex: All·Age: 18+

Code: NCT05983276·Phase 2·Recruiting·Listed Aug 2023

Apply to this trial

MANAGE-AF Registry -MANAGEment of Atrial Fibrillation Outcomes Registry (MANAGE-AF)

for Atrial Fibrillation

1 location in Chicago

Sponsor: CorVita Science Foundation

Sex: All·Age: 18+

Code: NCT05978466·Recruiting·Listed Aug 2023

Apply to this trial

The Pediatric Lupus Nephritis Mycophenolate Mofetil (PLUMM) Study

for Lupus Nephritis

Sites in Chicago +18 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: 8 - 20

Code: NCT05538208·Phase 2·Recruiting·Listed Sep 2022

Apply to this trial

A Prospective Analysis of Long-Term Clinical Outcomes and 3D Spine Growth in Anterior Vertebral Body Tethering

for Scoliosis Idiopathic

Sites in Chicago +10 more locations

Sponsor: Pediatric Spine Foundation

Sex: All·Age: Up to 18

Code: NCT04914507·Recruiting·Listed Jun 2021

Apply to this trial

Alzheimer's National Registry for Treatment and Diagnostics(ALZ-NET)

for Alzheimer Disease

1 location in Chicago

Sponsor: Alzheimer's Disease and Related Disorders Association, Inc

Sex: All·Age: 18+

Code: NCT06170268·Recruiting·Listed Dec 2023

Apply to this trial

Keeping it LITE: Exploring HIV Risk in Vulnerable Youth With Limited Interaction and Digital Health Intervention

for HIV Infections

1 location in Chicago

Sponsor: Hektoen Institute for Medical Research

Sex: All·Age: 13 - 34·Accepts healthy volunteers

Code: NCT05848570·Recruiting·Listed May 2023

Apply to this trial

CPI-613 (Devimistat) in Combination With Hydroxychloroquine and 5-fluorouracil or Gemcitabine in Treating Patients With Advanced Chemorefractory Solid Tumors

for Advanced Biliary Tract Carcinoma

1 location in Chicago

Sponsor: Northwestern University

Sex: All·Age: 18+

Code: NCT05733000·Phase 2·Recruiting·Listed Feb 2023

Apply to this trial

SVS VQI TransCarotid Revascularization Surveillance Project

for Carotid Artery Disease

1 location in Chicago

Sponsor: Society for Vascular Surgery Patient Safety Organization

Sex: All·Age: 18+

Code: NCT02850588·Recruiting·Listed Aug 2016

Apply to this trial

Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital Toxoplasmosis

for Toxoplasmosis

1 location in Chicago

Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Sex: All·Age: All ages

Code: NCT00004317·Phase 4·Recruiting·Listed Oct 1999

Apply to this trial

Adoptive T Cell Immunotherapy for Advanced Melanoma Using Engineered Lymphocytes

for Melanoma

1 location in Maywood

Sponsor: Loyola University

Sex: All·Age: 18 - 89

Code: NCT02870244·Phase 1·Recruiting·Listed Aug 2016

Apply to this trial

Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function

for Overactive Bladder (OAB)

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18+

Code: NCT06944392·Recruiting·Listed Apr 2025

Apply to this trial

Sleep, Diabetic Retinopathy and Melatonin

for Diabetes Mellitus

1 location in Chicago

Sponsor: University of Illinois at Chicago

Sex: All·Age: 40 - 65

Code: NCT04547439·Phase 2·Recruiting·Listed Sep 2020

Apply to this trial

Shockwave in Postoperative Breast Reconstruction Fibrosis

for Fibrosis Breast

1 location in Chicago

Sponsor: Northwestern University

Sex: Female·Age: 18+

Code: NCT06919042·Recruiting·Listed Apr 2025

Apply to this trial

Development of a Mobile Health Intervention for Electronic Cigarette Use Among Young Adults

for Electronic Nicotine Delivery Systems

1 location in Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 26·Accepts healthy volunteers

Code: NCT06395415·Recruiting·Listed May 2024

Apply to this trial

Proximal Internal Carotid Artery Acute Stroke Secondary to Tandem or Local Occlusion Thrombectomy Trial

for Acute Ischemic Stroke

Sites in Chicago, Winfield +49 more locations

Sponsor: Mercy Health Ohio

Sex: All·Age: 18 - 79

Code: NCT05611242·Phase 3·Recruiting·Listed Nov 2022

Apply to this trial