Paid Clinical Trials in Indianapolis, IN

As of June 2026, 928 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Indianapolis offers studies at sites including Indiana University for conditions such as Heart Failure, Breast Cancer, Prostate Cancer, Dementia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Indianapolis

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About research studies in Indianapolis

Indianapolis has approximately 928 recruiting research studies across a wide range of therapeutic areas. Indiana hosts a diverse network of universities, academic medical centers, and community hospitals that run clinical trials across oncology, cardiology, neurology, and many other therapeutic areas.

Top Research Study Locations in Indianapolis

Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
Indiana UniversityAlzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia115
Riley Hospital for ChildrenMalignant Solid Neoplasm, Neuroblastoma, Acute Myeloid Leukemia69
Indiana University School of MedicineDementia, Alzheimers Disease, Alzheimers Disease, Familial56
Indiana University/Melvin and Bren Simon Cancer CenterStage IV Lung Cancer AJCC v8, Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v842
Indiana University Melvin and Bren Simon Comprehensive Cancer CenterSmall Cell Lung Cancer, Breast Cancer, Extensive Stage Small Cell Lung Cancer31
Indiana University Health University HospitalEosinophilic Esophagitis, Gastroparesis, Obesity or Overweight22
IU Health Methodist HospitalCoronary Artery Disease, Atrial Fibrillation, Breast Cancer21
Indiana University HealthMyasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke21
Saint Catherine HospitalAnatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma20
Community Health NetworkColorectal Cancer, Head and Neck Squamous Cell Carcinoma, Metastatic Breast Cancer17
Dawes Fretzin Clinical Research Group, LLCAtopic Dermatitis, Plaque Psoriasis, Severe Alopecia Areata16
Indiana University HospitalGastroparesis, Abnormal Uterine Bleeding, Achalasia16
Sidney and Lois Eskenazi HospitalAnatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Breast Cancer16
Ascension Saint Vincent Indianapolis HospitalAcute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia15
Franciscan Health IndianapolisAnatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity15
Riley Children's HospitalBiliary Atresia, Bowel Incontinence, CLOVES Syndrome13
Indiana University Health Methodist HospitalAcute Ischemic Stroke, Acute Myocardial Infarction (AMI), Atherosclerotic Cardiovascular Disease (ASCVD)11
Richard L. Roudebush VA Medical Center, Indianapolis, INProstate Cancer, Cancer Survivor, Chronic Low Back Pain11
Franciscan HealthNeoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Anal Fistula9
Indiana University Melvin and Bren Simon Cancer CenterLocoregionally Recurrent Hormone-receptor Positive Breast Cancer, Metastatic Hormone Receptor Positive Breast Cancer, Neoplasm Metastasis9
Riley Hospital for Children at Indiana University HealthADHD - Attention Deficit Disorder With Hyperactivity, Adult Gynecological Procedures, Adult Surgical Procedures9
Ascension St. VincentAtrial Fibrillation, Aortic Valve Disease, Aortic Valve Stenosis8
IU Health University HospitalContraception, Crohn Disease, Graves Disease8
Community Cancer Center NorthBreast Cancer, Brain Metastases, Carcinoma, Non-Small-Cell Lung7
Price Vision GroupCataract, Corneal Edema, Corneal Endothelial Decompensation7

Active & Upcoming Studies in Indianapolis (2026)

Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cancer & tumors (248 active studies)

Mental health & behavior (28 active studies)

Common conditions studied in Indianapolis

  • Heart Failure (17 active studies). Heart failure trials explore SGLT-2 inhibitors, novel myosin modulators, and device-based therapies for both reduced and preserved ejection fraction.
  • Breast Cancer (13 active studies). Breast cancer trials evaluate new hormone therapies, targeted drugs, and immunotherapy combinations aimed at improving survival and reducing recurrence.
  • Prostate Cancer (12 active studies). Prostate cancer studies test next-generation hormone therapies, PARP inhibitors, and radioligand treatments for both localized and advanced disease.
  • Dementia (10 active studies). ENT (otolaryngology) trials evaluate new treatments for hearing loss, swallowing disorders, and head and neck cancers — covering pharmacologic, surgical, and rehabilitative approaches.
  • Obesity (10 active studies). Obesity trials evaluate GLP-1 and GIP receptor agonists, novel metabolic drugs, and combined lifestyle interventions for sustainable weight loss.
  • Alzheimer Disease (9 active studies). Alzheimer's research investigates anti-amyloid antibodies, tau-targeted therapies, and lifestyle interventions aimed at slowing cognitive decline.

Leading research sponsors in Indianapolis

  • Indiana University
  • Eli Lilly and Company
  • National Cancer Institute (NCI)
  • Children's Oncology Group
  • AbbVie

Local regulations and guidelines

Clinical trials in Indiana are governed by U.S. Food and Drug Administration (FDA) regulations, Office for Human Research Protections (OHRP) standards, and federal HIPAA privacy rules. Every study is reviewed by an Institutional Review Board (IRB) to protect participant safety and ensure informed consent. Indiana research additionally follows state public health department oversight and any applicable state privacy statutes.

Compensation & what to expect

How payment typically works
Compensation is most often provided through reloadable electronic study cards or direct deposit, paid out per completed visit rather than as a lump sum. Amounts vary by the time required, the number of visits, and the study's complexity — overnight stays and inpatient pharmacology studies generally pay more than short outpatient surveys. The exact amount is disclosed in writing during informed consent before any visit.
Healthy volunteers
Healthy participants aged 18 and older can earn compensation by joining vaccine, pharmacology, and biomarker studies in Indianapolis. These trials check how a new drug or vaccine behaves in healthy bodies before later-phase testing. Many sites maintain a healthy-volunteer registry so you hear about new opportunities first.
What's included beyond payment
Most trials cover study-related medical care at no cost — physical exams, lab work, imaging, the investigational treatment itself, and follow-up visits with the research team. Insurance is not required to participate. Free check-ups and access to specialists are common reasons participants return for additional studies.
Travel and time
Many sponsors reimburse travel, parking, mileage, and lost wages for visit days. Long-running studies and trials that require frequent visits often raise stipends accordingly. Ask the study coordinator for the visit schedule and reimbursement policy before you commit.
Asking about compensation
Compensation is set per protocol and per site, so figures are not published in trial registries. The fastest way to confirm payment for a specific study is to contact the recruiting site listed on the study record. Coordinators are accustomed to this question and will quote the per-visit and total amounts up front.

How to find a clinical trial in Indianapolis

Hipa.ai aggregates every recruiting study in Indianapolis from ClinicalTrials.gov and refreshes the list daily. Use the filters above to narrow by condition, facility, age, phase, or healthy-volunteer eligibility, then click any study title to view full details — eligibility criteria, intervention, location, and sponsor contact information. To enroll, reach out to the central study contact listed on the study detail page; the research coordinator will walk you through the screening process.

Frequently asked questions

How many paid clinical trials are currently recruiting in Indianapolis?

There are approximately 928 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Indianapolis pay participants?

Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Indianapolis?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Indianapolis?

The most common conditions under active study in Indianapolis include Heart Failure (17), Breast Cancer (13), Prostate Cancer (12), Dementia (10), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Indianapolis?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Indianapolis?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Indianapolis?

Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Indianapolis right now?

The largest active categories in Indianapolis are Cancer & tumors (248), Cardiovascular (69), Neurology & pain (50). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

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Related healthcare resources in Indiana

Trials by condition in Indianapolis