Paid Clinical Trials in Indianapolis, IN
As of July 2026, 861 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Indianapolis offers studies at sites including Indiana University for conditions such as Heart Failure, Obesity, Prostate Cancer, Dementia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Indianapolis
Trials by drug in Indianapolis
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Newly added in Indianapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study of MZE782 in Adults With PKU
Miniaturized Breath-based Sensor for the Detection of Hypo- and Hyperglycemia
To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment
Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials
Overground Virtual Reality (VR) Gait Rehabilitation for Stroke
766 clinical trials
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
A Study of Brenipatide in Participants With Opioid Use Disorder
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Buntanetap in Participants With PD
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Study to Investigate Safety and Efficacy of Tapinarof Cream, 1% in Participants Ages 3 Months to < 24 Months With Atopic Dermatitis
A 16-Week Study to Learn About the Study Medicine Called Ritlecitinib in Adults With Long Lasting Painful Red Skin Lumps, Known by the Medical Term, Hidradenitis Suppurativa, or HS.
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
GATEWAY: Safety Evaluation of the MiniMed™ NMX8-AID System in Children and Adults Living With Diabetes
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
Top Research Study Locations in Indianapolis
Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Indiana University | Alzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia | 101 |
| Riley Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 65 |
| Indiana University School of Medicine | Dementia, Alzheimers Disease, Alzheimers Disease, Familial | 53 |
| Indiana University/Melvin and Bren Simon Cancer Center | Acute Myeloid Leukemia, Anatomic Stage II Breast Cancer AJCC v8, Stage IV Lung Cancer AJCC v8 | 33 |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Small Cell Lung Cancer, Germ Cell Tumor, Prostate Cancer | 27 |
| Indiana University Health | Myasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke | 21 |
| Saint Catherine Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 21 |
| Indiana University Health University Hospital | Eosinophilic Esophagitis, Gastroparesis, Obesity or Overweight | 20 |
| Community Health Network | Colorectal Cancer, Head and Neck Squamous Cell Carcinoma, Metastatic Breast Cancer | 19 |
| Indiana University Hospital | Gastroparesis, Abnormal Uterine Bleeding, Achalasia | 17 |
| IU Health Methodist Hospital | Coronary Artery Disease, Atrial Fibrillation, Breast Implant; Complications | 15 |
| Ascension Saint Vincent Indianapolis Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 14 |
| Dawes Fretzin Clinical Research Group, LLC | Atopic Dermatitis, Plaque Psoriasis, Alopecia | 14 |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Prostate Cancer, Actinic Keratosis, Anxiety | 14 |
| Sidney and Lois Eskenazi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 14 |
| Franciscan Health Indianapolis | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 11 |
| Riley Children's Hospital | Becker Muscular Dystrophy, Bowel Incontinence, CLOVES Syndrome | 11 |
| Franciscan Health | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms | 10 |
| Indiana University Health Methodist Hospital | Diabetic Foot Ulcer (DFU), Acute Ischemic Stroke, Atherosclerotic Cardiovascular Disease (ASCVD) | 10 |
| IU Health University Hospital | Contraception, Crohn Disease, Graves Disease | 9 |
| Ascension St. Vincent | Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Stenosis | 8 |
| Indiana University Melvin and Bren Simon Cancer Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 8 |
| Riley Hospital for Children at Indiana University Health | ADHD - Attention Deficit Disorder With Hyperactivity, Anxiety Disorders, Aortic Coarctation | 8 |
| Eskenazi Health | Hypertension, Aerobic Exercise, Alzheimer's Disease (Incl Subtypes) | 6 |
| Indiana University Medical Center | Benign Prostate Hypertrophy(BPH), Birth Defect, Borderline-resectable Pancreatic Cancer | 6 |
Active & Upcoming Studies in Indianapolis (2026)
Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (220 active studies)
- ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) · Indiana University
- Therapeutic Induction of Dermal Remodeling in Veterans to Prevent Actinic Neoplasia Caused by Chronic Environmental Exposure to Ultraviolet Radiation · VA Office of Research and Development
Cardiovascular (64 active studies)
- Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease · Indiana University
- LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial · Phase 2 · VA Office of Research and Development
Diabetes & metabolic (52 active studies)
- Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 · Indiana University
- A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide · Phase 3 · Novo Nordisk A/S
Neurology & pain (48 active studies)
- Overground Virtual Reality (VR) Gait Rehabilitation for Stroke · Indiana University
- Automated, Assistive, Non-Contact Sleep Quality Monitor for Individuals With Alzheimer's Disease · Indiana University
Mental health & behavior (25 active studies)
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, Phase 2 · Indiana University
Pediatric (13 active studies)
Eye & vision (6 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
HIV / STI (5 active studies)
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
- The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · Indiana University
Vaccines (2 active studies)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS) · Duke University
Common conditions studied in Indianapolis
- Heart Failure (15 active studies)
- Obesity (13 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Multiple Myeloma (9 active studies)
- Acute Myeloid Leukemia (8 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- National Cancer Institute (NCI)
- Eli Lilly and Company
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 861 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Heart Failure (15), Obesity (13), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (220), Cardiovascular (64), Diabetes & metabolic (52). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.