Paid Clinical Trials in Indianapolis, IN
As of September 2026, 881 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.
Indianapolis offers studies at sites including Indiana University for conditions such as Obesity, Heart Failure, Prostate Cancer, Dementia. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.
Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .
Trials by specialty in Indianapolis
Trials by drug in Indianapolis
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Newly added in Indianapolis
Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.
A Study to Assess the Efficacy and Safety of GIA632 Across a Range of Doses in Participants With Moderate to Severe Cutaneous Lichen Planus
A Study to Evaluate the Safety and Effectiveness of Upadacitinib in Pediatric Participants With Alopecia Areata
Non-invasive Prediction of EArly Cardiac rEjection
Study of Resmetirom in Children and Adolescents With MASH
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
779 clinical trials
A Research Study Comparing How Well Different Doses of the Medicine UBT251 Lower Blood Sugar in People With Type 2 Diabetes
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
A Phase 2b Study of the Effects of Camoteskimab in Adults With Moderate-to-Severe Atopic Dermatitis
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
An Open Label Extension (OLE) Study (Following Completion of CTQJ230A12301) to Evaluate Long-term Safety and Tolerability of Pelacarsen (TQJ230)
A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma
A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (PD) Participants With Motor Fluctuations
A Study of Brenipatide in Participants With Opioid Use Disorder
Study to Evaluate the Safety and Efficacy of Larsucosterol in Participants With Alcohol-associated Hepatitis (AH)
A Study to Assess the Effectiveness and Safety of IPN10200 Over Time in Adults With Moderate to Severe Wrinkle-like Lines Between the Eyebrows
A Study to Evaluate the Effectiveness and Safety of Setidegrasib, Given With Either mFOLFIRINOX or NALIRIFOX Chemotherapies, in People With Pancreatic Cancer
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults
Symbiotic-Lung-01 : A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer
Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
A Master Protocol of Multiple Agents in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (SYNERGY-Outcomes)
Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease
A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)
Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)
A Study of Buntanetap in Participants With PD
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events
A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer
Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer
Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
Ocular Assessments in Patients Treated With Tivdak® in Recurrent or Metastatic Cervical Cancer
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
REGN7508 Versus Acetylsalicylic Acid (ASA) for Venous Thromboprophylaxis After Total Knee Arthroplasty in Adult Participants
A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy
Top Research Study Locations in Indianapolis
Researchers run research studies in Indianapolis, IN at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.
| Site | Specializes in | Active trials |
|---|---|---|
| Indiana University | Alzheimer Disease, Amyotrophic Lateral Sclerosis, Dementia | 102 |
| Riley Hospital for Children | Malignant Solid Neoplasm, Acute Myeloid Leukemia, B Acute Lymphoblastic Leukemia | 65 |
| Indiana University School of Medicine | Dementia, Alzheimers Disease, Alzheimers Disease, Familial | 50 |
| Indiana University/Melvin and Bren Simon Cancer Center | Anatomic Stage II Breast Cancer AJCC v8, Acute Myeloid Leukemia, Anatomic Stage IIIA Breast Cancer AJCC v8 | 33 |
| Indiana University Melvin and Bren Simon Comprehensive Cancer Center | Small Cell Lung Cancer, Germ Cell Tumor, Prostate Cancer | 28 |
| Indiana University Health | Myasthenia Gravis, Acetabulum Fractures, Acute Ischemic Stroke | 21 |
| Saint Catherine Hospital | Anatomic Stage II Breast Cancer AJCC v8, Stage IIIB Lung Cancer AJCC v8, Advanced Esophageal Adenocarcinoma | 21 |
| Community Health Network | Colorectal Cancer, Pancreatic Ductal Adenocarcinoma, Head and Neck Squamous Cell Carcinoma | 19 |
| Indiana University Health University Hospital | Eosinophilic Esophagitis, Gastroparesis, Obesity or Overweight | 19 |
| Indiana University Hospital | Gastroparesis, Abnormal Uterine Bleeding, Achalasia | 16 |
| Ascension Saint Vincent Indianapolis Hospital | Acute Myeloid Leukemia, Malignant Solid Neoplasm, Mixed Phenotype Acute Leukemia | 14 |
| Dawes Fretzin Clinical Research Group, LLC | Atopic Dermatitis, Alopecia Areata, Eczema | 14 |
| IU Health Methodist Hospital | Coronary Artery Disease, Atrial Fibrillation, Breast Implant; Complications | 14 |
| Richard L. Roudebush VA Medical Center, Indianapolis, IN | Prostate Cancer, Actinic Keratosis, Anxiety | 14 |
| Sidney and Lois Eskenazi Hospital | Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIIA Breast Cancer AJCC v8, Anatomic Stage IIIB Breast Cancer AJCC v8 | 13 |
| Franciscan Health Indianapolis | Anatomic Stage IV Breast Cancer AJCC v8, Breast Cancer, Cardiotoxicity | 12 |
| Riley Children's Hospital | Becker Muscular Dystrophy, Bowel Incontinence, CLOVES Syndrome | 12 |
| Franciscan Health | Neoplasm Metastasis, Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms | 11 |
| Indiana University Health Methodist Hospital | Diabetic Foot Ulcer (DFU), Acute Ischemic Stroke, Atherosclerotic Cardiovascular Disease (ASCVD) | 11 |
| Ascension St. Vincent | Coronary Artery Disease, Aortic Valve Disease, Aortic Valve Stenosis | 9 |
| IU Health University Hospital | Colitis, Ulcerative, Contraception, Crohn Disease | 9 |
| Riley Hospital for Children at Indiana University Health | ADHD - Attention Deficit Disorder With Hyperactivity, Anxiety Disorders, Aortic Coarctation | 8 |
| Indiana University Melvin and Bren Simon Cancer Center | Neoplasm Metastasis, Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | 7 |
| Eskenazi Health | Hypertension, Aerobic Exercise, Alzheimer's Disease (Incl Subtypes) | 6 |
| Indiana University Medical Center | BPH (Benign Prostatic Hyperplasia), Birth Defect, Borderline-resectable Pancreatic Cancer | 6 |
Active & Upcoming Studies in Indianapolis (2026)
Recruiting trials in Indianapolis grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.
Cancer & tumors (232 active studies)
- ImmuNe ParameTERs to Predict Immunotherapy REsponse and Toxicity (INTERPRET) · Indiana University
- Safety and Efficacy of OTL78 (Zopocianine) · Phase 2, Phase 3 · Clinton Bahler
Cardiovascular (70 active studies)
- Utilizing Carbon Dioxide for Assessing Coronary Blood Flow in Subjects With Coronary Artery Disease · Indiana University
- LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial · Phase 2 · VA Office of Research and Development
Diabetes & metabolic (54 active studies)
- Effect Of Percutaneous Electrical Nerve Field Stimulation on Symptom Control/Nervous System Activity in Patients w/Diabetes Types 1/2 · Indiana University
- Supplementation of Gut-brain Axis (GLP-1)-Activating Carbohydrates for Increasing Satiety in Adolescents With Obesity · Phase 2 · Indiana University
Neurology & pain (50 active studies)
Mental health & behavior (22 active studies)
- Improving Mental Healthcare Outcomes for Minoritized Veterans Through a Peer-led, Patient Navigation Program (PARTNER-MH 2.0) · VA Office of Research and Development
- Psilocybin Assisted Psychotherapy for Treatment Resistant Depression and Co-occurring Substance Use Disorder · Phase 1, Phase 2 · Indiana University
Pediatric (14 active studies)
HIV / STI (5 active studies)
- A Study to Evaluate the Use of Resmetirom in Participants With MASLD and HIV · Phase 2 · Naga P. Chalasani
- The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · Indiana University
Eye & vision (5 active studies)
- An Exploratory Efficacy and Safety Study of DFL24498 Topical Ophthalmic Solution Compared With Vehicle in Participants With Dry Eye Disease · Phase 2 · Dompé Farmaceutici S.p.A
- A Phase 2, Randomized, Placebo Controlled, Multicenter, Masked Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamics of Multidose APL 3007 in Combination With Syfovre/Pegcetacoplan (APL-2) in Patients Diagnosed With Geographic Atrophy Secondary to Age Related Macular Degeneratio · Phase 2 · Apellis Pharmaceuticals, Inc.
Vaccines (1 active study)
- Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children · Phase 3 · University of Alabama at Birmingham
Common conditions studied in Indianapolis
- Obesity (16 active studies)
- Heart Failure (15 active studies)
- Prostate Cancer (11 active studies)
- Dementia (10 active studies)
- Coronary Artery Disease (9 active studies)
- Multiple Myeloma (9 active studies)
Leading research sponsors in Indianapolis
- Indiana University
- Eli Lilly and Company
- National Cancer Institute (NCI)
- Children's Oncology Group
- VA Office of Research and Development
Frequently asked questions
How many paid clinical trials are currently recruiting in Indianapolis?
There are approximately 881 recruiting clinical trials in Indianapolis, Indiana listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.
Do clinical trials in Indianapolis pay participants?
Most recruiting trials in Indianapolis compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.
Who can participate in a clinical trial in Indianapolis?
Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.
What conditions are most commonly studied in Indianapolis?
The most common conditions under active study in Indianapolis include Obesity (16), Heart Failure (15), Prostate Cancer (11), Dementia (10), among many others. Browse the list above to explore every recruiting trial.
Are there clinical trials for healthy volunteers in Indianapolis?
Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Indianapolis on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.
How do I enroll in a clinical trial in Indianapolis?
Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.
Where can I take part in paid clinical trials in Indianapolis?
Recruiting research sites in Indianapolis include Indiana University, Riley Hospital for Children, Indiana University School of Medicine, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.
What kinds of studies are recruiting in Indianapolis right now?
The largest active categories in Indianapolis are Cancer & tumors (232), Cardiovascular (70), Diabetes & metabolic (54). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.