Paid Clinical Trials in Indianapolis, IN

As of September 2026, 881 paid clinical trials are recruiting in Indianapolis, Indiana. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 17, 2026.

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779 clinical trials

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A Double Blind, Randomized Controlled Study, Evaluating the Safety and Efficacy of RD2 Ver.02 For the Management of Anal Fistulas

for Anal Fistula

Sites in Indianapolis +7 more locations

Sponsor: RedDress Ltd.

Sex: All·Age: 18+

Code: NCT05641844·Recruiting·Listed Dec 2022

Apply to this trial

AvertD Post-Approval Study

for Opioid Use Disorder

1 location in Indianapolis

Sponsor: Prescient Medicine Holdings, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07135323·Recruiting·Listed Aug 2025

Apply to this trial

Phase II Study of Artesunate Ointment for the Treatment of Vulvar High Grade Squamous Intraepithelial Lesions (Vulvar HSIL, VIN2/3)

for Vulvar Diseases

Sites in Indianapolis +4 more locations

Sponsor: Frantz Viral Therapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06075264·Phase 2·Recruiting·Listed Oct 2023

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Post-Market Clinical Study of Functional Motion Outcomes in Subjects Treated With the Minuteman Device

for Degenerative Conditions of the Lumbar Spine

Sites in Indianapolis +5 more locations

Sponsor: Spinal Simplicity LLC

Sex: All·Age: 18+

Code: NCT06355791·Recruiting·Listed Apr 2024

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Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Budesonide Extended-release Tablets in Pediatric Subjects Aged 5 to 17 Years With Active, Mild to Moderate Ulcerative Colitis

for Ulcerative Colitis

Sites in Indianapolis +3 more locations

Sponsor: Bausch Health Americas, Inc.

Sex: All·Age: 5 - 17

Code: NCT04314375·Phase 4·Recruiting·Listed Mar 2020

Apply to this trial

Non-Invasive Quantification of Liver Health in NASH (N-QUAN)

for NASH - Nonalcoholic Steatohepatitis

Sites in Indianapolis +5 more locations

Sponsor: Perspectum

Sex: All·Age: 18 - 75

Code: NCT04054310·Recruiting·Listed Aug 2019

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A Single-arm, Pivotal Study to Evaluate Acute Device and Technical Success of the CGuard Prime Carotid Stent System When Used in Conjunction to the ENROUTE Transcarotid Neuroprotection System in Patients Undergoing Carotid Artery Stenting Via the Transcarotid Artery Revascularization Approach

for Carotid Artery Diseases

Sites in Indianapolis +7 more locations

Sponsor: InspireMD

Sex: All·Age: 18 - 79

Code: NCT06653387·Recruiting·Listed Oct 2024

Apply to this trial

The KinematX Midcarpal Total Wrist Arthroplasty Registry

for Scapholunate Advanced Collapse (SLAC)

Sites in Indianapolis +3 more locations

Sponsor: Extremity Medical

Sex: All·Age: 18 - 85

Code: NCT05719935·Recruiting·Listed Feb 2023

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An Observational Study of Carbaglu® for the Treatment of MMA and PA in Adults and Pediatrics

for Hyperammonemia

Sites in Indianapolis +4 more locations

Sponsor: RECORDATI GROUP

Sex: All·Age: All ages

Code: NCT05040178·Recruiting·Listed Sep 2021

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Clinical Evaluation of BCDx for Monitoring of Recurrence in Non-Muscle Invasive Bladder Cancer

for Bladder Cancer

Sites in Indianapolis +2 more locations

Sponsor: Early is Good Inc.

Sex: All·Age: 18+

Code: NCT05982561·Recruiting·Listed Aug 2023

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PSMA-PET to Guide Prostatectomy

for Prostate Cancer

1 location in Indianapolis

Sponsor: Five Eleven Pharma, Inc.

Sex: Male·Age: 40 - 80

Code: NCT05381103·Phase 2, Phase 3·Recruiting·Listed May 2022

Apply to this trial

A Study for the PanCystPro Assay in the Management of Pancreatic Cystic Lesions

for Pancreatic Cystic Lesions

Sites in Indianapolis +2 more locations

Sponsor: Amplified Sciences Inc

Sex: All·Age: 18+

Code: NCT06894329·Recruiting·Listed Mar 2025

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A Study of LM-24C5 For Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Indianapolis +5 more locations

Sponsor: LaNova Medicines Limited

Sex: All·Age: 18+

Code: NCT06187402·Phase 1, Phase 2·Recruiting·Listed Jan 2024

Apply to this trial

CorMatrix Cor TRICUSPID ECM Valve Replacement Study

for Tricuspid Valve Disease

Sites in Indianapolis +3 more locations

Sponsor: Corvivo Cardiovascular, Inc.

Sex: All·Age: 1 - 85·Accepts healthy volunteers

Code: NCT02397668·Recruiting·Listed Mar 2015

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Comparison of Standard vs. Accelerated Corneal Crosslinking

for Keratoconus

1 location in Indianapolis

Sponsor: Price Vision Group

Sex: All·Age: 10+

Code: NCT03922542·Phase 2, Phase 3·Recruiting·Listed Apr 2019

Apply to this trial

Corneal Crosslinking for Treatment of Corneal Neovascularization

for Corneal Neovascularization

1 location in Indianapolis

Sponsor: Price Vision Group

Sex: All·Age: 18+

Code: NCT04787471·Phase 2, Phase 3·Recruiting·Listed Mar 2021

Apply to this trial

4-day Plaque Accumulation Model Evaluating Compound Containing Gum

for Dental Plaque Accumulation

1 location in Indianapolis

Sponsor: Lactea Therapeutics, LLC

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06984744·Recruiting·Listed May 2025

Apply to this trial

CorMatrix Cor TRICUSPID ECM Valve Replacement - Pivotal Study

for Tricuspid Valve Disease

Sites in Indianapolis +1 more location

Sponsor: Corvivo Cardiovascular, Inc.

Sex: All·Age: All ages

Code: NCT05742906·Recruiting·Listed Feb 2023

Apply to this trial

Study to Assess the Use of Tezampanel for Opioid Withdrawal Syndrome in Treatment-Seeking Patients With Opioid Use Disorder

for Opioid Use Disorder

1 location in Indianapolis

Sponsor: Proniras Corporation

Sex: All·Age: 18 - 65

Code: NCT06538558·Phase 1·Recruiting·Listed Aug 2024

Apply to this trial

Post-Market Clinical Investigation of the IotaSOFT Insertion System

for Hearing Loss, Cochlear

Sites in Indianapolis +2 more locations

Sponsor: iotaMotion, Inc.

Sex: All·Age: 12+

Code: NCT06664697·Recruiting·Listed Oct 2024

Apply to this trial

CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting

for Cardiac Valve Disease

Sites in Indianapolis +6 more locations

Sponsor: Corcym S.r.l

Sex: All·Age: All ages

Code: NCT05002543·Recruiting·Listed Aug 2021

Apply to this trial

Overground Virtual Reality (VR) Gait Rehabilitation for Stroke

for Stroke

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07676578·Recruiting·Listed Jun 2026

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Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

for Duchenne Muscular Dystrophy (DMD)

Sites in Indianapolis +8 more locations

Sponsor: Vanderbilt University Medical Center

Sex: All·Age: All ages

Code: NCT07674758·Recruiting·Listed Jun 2026

Apply to this trial

CAMPR-II RWE TRIAL: A Saline-hydrated Allogeneic Dual-layer Amniotic Membrane Product or a Synthetic, Resorbable Polymeric Wound Matrix to a Coarsened Exact Matched Retrospective Control Cohort of Hard to Heal DFUs and VLUs

for Wound, Foot

Sites in Indianapolis +6 more locations

Sponsor: Capsicure, LLC

Sex: All·Age: 18+

Code: NCT07701590·Recruiting·Listed Jul 2026

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Miniaturized Breath-based Sensor for the Detection of Hypo- and Hyperglycemia

for Diabetes

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 7 - 25

Code: NCT07696273·Recruiting·Listed Jul 2026

Apply to this trial

Effect of Gastric Electrical Stimulation on Serum Insulin Levels

for Gastroparesis Nondiabetic

2 locations in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 70

Code: NCT07635576·Recruiting·Listed Jun 2026

Apply to this trial

Point-of-care Ultrasound Utility in the Free Clinic Setting

for Point of Care Ultrasound (POCUS)

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07556341·Recruiting·Listed Apr 2026

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rTMS Induced Reduction in M1 Excitability

for Cortical Excitability

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 45·Accepts healthy volunteers

Code: NCT07588113·Recruiting·Listed May 2026

Apply to this trial

Pharmacokinetics and Placental Transfer of Caffeine

for Preterm Labor With Preterm Delivery

1 location in Indianapolis

Sponsor: Indiana University

Sex: Female·Age: 18+

Code: NCT07570121·Phase 1·Recruiting·Listed May 2026

Apply to this trial

A Study of Methylprednisolone in People Having Liver Surgery

for Hepatectomy

Sites in Indianapolis +18 more locations

Sponsor: Memorial Sloan Kettering Cancer Center

Sex: All·Age: 18+

Code: NCT07507643·Phase 3·Recruiting·Listed Apr 2026

Apply to this trial

Testing Whether Hormone Therapy With Ribociclib is as Effective as Chemotherapy Followed by Hormone Therapy With Ribociclib for the Treatment of High Anatomic Stage Breast Cancer With Low Recurrence Risk, The RxFINE-Low Trial

for Anatomic Stage II Breast Cancer AJCC v8

Drug: Ribociclib

Sites in Indianapolis +175 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07391774·Phase 3·Recruiting·Listed Feb 2026

Apply to this trial

Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

Sites in Indianapolis, Valparaiso +346 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting·Listed Dec 2025

Apply to this trial

My Path to Quit Tobacco

for Smoking Cessation

Sites in Indianapolis +4 more locations

Sponsor: University of Wisconsin, Madison

Sex: All·Age: 21+·Accepts healthy volunteers

Code: NCT07419425·Phase 4·Recruiting·Listed Feb 2026

Apply to this trial

Clinical Trial Comparing the Efficacy of Two Teletherapy Programs at Improving Psychological Health in People With Brain Injury

for Mild Traumatic Brain Injury

Sites in Indianapolis +2 more locations

Sponsor: Hackensack Meridian Health

Sex: All·Age: 18+

Code: NCT07436754·Recruiting·Listed Feb 2026

Apply to this trial

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

for Mild Cognitive Impairment

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 65+

Code: NCT07499570·Recruiting·Listed Mar 2026

Apply to this trial

Caring for Caregivers of Individuals With Alzheimer's Disease

for Intervention Group

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT07486037·Recruiting·Listed Mar 2026

Apply to this trial

Virtual Reality Cognitive Intervention for Critically Ill Delirium Survivors (VR-Cog)

for Intensive Care Unit Delirium

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 50+

Code: NCT07496255·Recruiting·Listed Mar 2026

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Indianapolis, Carmel +1087 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Indianapolis, New Albany +625 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

Apply to this trial

Circulating Tumor DNA in Stage I, II, and III Germ-Cell Tumors

for Germ Cell Cancer Metastatic

1 location in Indianapolis

Sponsor: Indiana University

Sex: All·Age: 18+

Code: NCT07401316·Recruiting·Listed Feb 2026

Apply to this trial