Clinical Trials at University of Iowa

As of June 2026, 196 paid clinical trials are recruiting at University of Iowa in Iowa City, Iowa. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 3, 2026.

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196 clinical trials at University of Iowa

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Real-time Personalized Brain State-dependent TMS After Stroke

for Stroke

1 location in Iowa City

Sponsor: Sara Hussain

Sex: All·Age: 18+

Code: NCT06533176·Recruiting

Apply to this trial

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

for Peripheral Neuropathy

3 locations incl. San Francisco

Sponsor: Elpida Therapeutics SPC

Sex: All·Age: All ages

Code: NCT06151600·Recruiting

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

50 locations incl. Gilbert

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting

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From Opinion to Evidence: Multi-site Evaluation of Custom Dynamic Orthosis Best Practices

for Foot Injury

5 locations incl. San Diego

Sponsor: Jason Wilken

Sex: All·Age: 18 - 65

Code: NCT06352788·Recruiting

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Dime La VerDAD: Verify, Debunk, and Disseminate

for Influenza

4 locations incl. Chicago

Sponsor: University of Chicago

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT06417762·Recruiting

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Parasitic Ulcer Treatment Trial

for Acanthamoeba Keratitis

13 locations incl. San Francisco

Sponsor: Jeremy Keenan, MD, MPH

Sex: All·Age: 8+

Code: NCT06213649·Phase 3·Recruiting

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Dichoptic Treatment for Amblyopia in Children 4 to 7 Years of Age

for Amblyopia

73 locations incl. Birmingham

Sponsor: Jaeb Center for Health Research

Sex: All·Age: 4 - 7

Code: NCT06380517·Phase 3·Recruiting

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A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

for Neutropenia

22 locations incl. Phoenix

Sponsor: X4 Pharmaceuticals

Sex: All·Age: 12+

Code: NCT06056297·Phase 3·Recruiting

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A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).

for Pediatric

Drug: Aficamten

26 locations incl. Phoenix

Sponsor: Cytokinetics

Sex: All·Age: 12 - 17

Code: NCT06412666·Phase 2, Phase 3·Recruiting

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Multi-Center Clean Air Randomized Controlled Trial in COPD

for Chronic Obstructive Pulmonary Disease (COPD)

11 locations incl. Birmingham

Sponsor: JHSPH Center for Clinical Trials

Sex: All·Age: 40+

Code: NCT06376994·Phase 3·Recruiting

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Neuronal and Network Mechanisms of Electrocortical Stimulation

for Epilepsy

3 locations incl. Chicago

Sponsor: Northwestern University

Sex: All·Age: 18 - 80

Code: NCT06391294·Enrolling By Invitation

Treatment Targets in Spanish and English Bilingual Speech Intervention

for Speech Sound Disorder

1 location in Iowa City

Sponsor: Philip Combiths

Sex: All·Age: 3 - 8

Code: NCT06416306·Phase 1·Recruiting

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Copper Cu 64 PSMA I&T PET Imaging in Men With Newly Diagnosed Prostate Cancer

for Prostate Cancer

43 locations incl. Little Rock

Sponsor: Curium US LLC

Sex: Male·Age: 18+

Code: NCT06235151·Phase 3·Recruiting

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A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

for Alzheimer Disease

47 locations incl. Phoenix

Sponsor: Alzheimer's Disease Cooperative Study (ADCS)

Sex: All·Age: 50 - 89

Code: NCT06223360·Phase 2·Recruiting

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

41 locations incl. Birmingham

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting

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Defactinib and Avutometinib, With or Without Encorafenib, for the Treatment of Patients With Brain Metastases From Cutaneous Melanoma

for Cutaneous Melanoma

Drug: Avutometinib

2 locations incl. Iowa City

Sponsor: University of Utah

Sex: All·Age: 18+

Code: NCT06194929·Phase 1, Phase 2·Recruiting

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VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

for Crohn's Disease

12 locations incl. Sun City

Sponsor: Alimentiv Inc.

Sex: All·Age: 18+

Code: NCT06249555·Recruiting

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Utilizing Novel Blood RNA Biomarkers as a Diagnostic Tool in the Identification of Long COVID-19

for Long COVID

3 locations incl. Iowa City

Sponsor: MaxWell Clinic, PLC

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06311435·Recruiting

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OLE Study of Carbetocin Nasal Spray for the Treatment of Hyperphagia in Prader-Willi Syndrome

for Hyperphagia in Prader-Willi Syndrome

19 locations incl. Birmingham

Sponsor: ACADIA Pharmaceuticals Inc.

Sex: All·Age: 5 - 30

Code: NCT06420297·Phase 3·Enrolling By Invitation

Reliability of Force Measurement Within the Carbon Fiber Orthosis Proximal Cuff

for Healthy

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 90·Accepts healthy volunteers

Code: NCT06127264·Recruiting

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The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

for Cesarean Delivery

34 locations incl. Little Rock

Sponsor: Yale University

Sex: Female·Age: 15 - 55·Accepts healthy volunteers

Code: NCT06030063·Recruiting

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An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

for Friedreich Ataxia

8 locations incl. Los Angeles

Sponsor: Larimar Therapeutics, Inc.

Sex: All·Age: 2 - 60

Code: NCT06447025·Phase 2·Recruiting

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Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery

for Hearing Loss, Sensorineural

1 location in Iowa City

Sponsor: iotaMotion, Inc.

Sex: All·Age: 12+

Code: NCT06664710·Recruiting

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Complex Aneurysm Registry - Real-World Evidence Data Collection Intracranial Aneurysm Treatment Devices

for Aneurysm Cerebral

5 locations incl. Hollywood

Sponsor: Microvention-Terumo, Inc.

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT06215105·Enrolling By Invitation

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

for Delirium

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 65+

Code: NCT05461092·EARLY_Phase 1·Recruiting

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Sex Differences in the Vascular Effects of E-cigarette Use

for E-cigarette Use

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT06159608·EARLY_Phase 1·Recruiting

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Hyperpolarized 129Xe MRI Lung Health Cohort

for Healthy

6 locations incl. Chicago

Sponsor: University of Kansas Medical Center

Sex: All·Age: 25 - 35

Code: NCT05766384·Recruiting

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Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

for Soft Tissue Sarcoma

26 locations incl. Phoenix

Sponsor: Polaris Group

Sex: All·Age: 18 - 99

Code: NCT05712694·Phase 3·Recruiting

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Open-Label Extension of EDG-5506 in Participants With Becker Muscular Dystrophy

for Becker Muscular Dystrophy

24 locations incl. Little Rock

Sponsor: Edgewise Therapeutics, Inc.

Sex: Male·Age: All ages

Code: NCT06066580·Phase 2·Enrolling By Invitation

Daily Aspirin Treatment After Preeclampsia

for Preeclampsia

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50

Code: NCT06168461·EARLY_Phase 1·Recruiting

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Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive Tumors

for Neuroendocrine Tumors Unresectable

19 locations incl. Jacksonville

Sponsor: Perspective Therapeutics

Sex: All·Age: 18 - 90

Code: NCT05636618·Phase 1, Phase 2·Recruiting

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Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss

for Sensorineural Hearing Loss, Bilateral

6 locations incl. San Francisco

Sponsor: Akouos, Inc.

Sex: All·Age: All ages

Code: NCT05821959·Phase 1, Phase 2·Recruiting

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Role of NADPH Oxidase in Microvascular Dysfunction Following GDM

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05946798·EARLY_Phase 1·Recruiting

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Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

for Sepsis

10 locations incl. Gainesville

Sponsor: University of Minnesota

Sex: All·Age: 65+

Code: NCT05758246·Phase 2·Recruiting

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A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

for Primary IgA Nephropathy

40 locations incl. Alabaster

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05797610·Phase 3·Recruiting

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A Long-Term Safety Trial of LUM-201 in Children With Idiopathic Growth Hormone Deficiency Who Have Previously Completed a LUM-201 Clinical Trial (OraGrowtH211)

for Growth Hormone Deficiency

6 locations incl. Iowa City

Sponsor: Lumos Pharma

Sex: All·Age: 5 - 14

Code: NCT05796440·Phase 2·Enrolling By Invitation

Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

for Pulmonary Embolism

40 locations incl. Birmingham

Sponsor: NYU Langone Health

Sex: All·Age: 18+

Code: NCT05591118·Phase 3·Recruiting

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Emergency Preparedness for Caregivers of Persons With Dementia: Disaster PrepWise

for Caregiver Resilience and Stress

1 location in Iowa City

Sponsor: Sato Ashida

Sex: All·Age: 18+

Code: NCT05619263·Recruiting

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Oxidative Stress in Microvascular Dysfunction Following Gestational Diabetes

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05946785·EARLY_Phase 1·Recruiting

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Pregnancy 24/7 Offspring Study

for Healthy

3 locations incl. Iowa City

Sponsor: Kara Whitaker

Sex: All·Age: 0 - 47·Accepts healthy volunteers

Code: NCT07172880·Recruiting

Apply to this trial