Paid Clinical Trials in Iowa City, IA

As of August 2026, 554 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Iowa City offers studies at sites including University of Iowa for conditions such as Acute Myeloid Leukemia, Breast Cancer, Multiple Myeloma, Hearing Loss, Sensorineural. Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: .

Trials by specialty in Iowa City

Oncology· 203Blood cancer· 76Women's health· 32Neurology· 28Brain disorders· 27Cardiology· 24Breast oncology· 23Heart disease· 21Lung oncology· 20GI oncology· 16Autoimmune disease· 16Behavioral health· 15

Trials by drug in Iowa City

Methotrexate· 9Dexamethasone· 7Prednisone· 7Letrozole· 4Prednisolone· 4Acetylcholine· 3Anastrozole· 3Ketamine· 3Folinic acid· 3Palbociclib· 3SoC· 3Education· 2Exercise· 2Metformin· 2
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Newly added in Iowa City

Posted to ClinicalTrials.gov within the last 60 days — these studies are just starting to recruit.

510 clinical trials

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Nivolumab in Combination With Chemotherapy in Participants With Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma (ROSETTA Gastric-204)

for Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Drug: Nivolumab
Sites in Iowa City +33 more locations
Sponsor: Bristol-Myers Squibb
Sex: All·Age: 18+
Code: NCT07221149·Phase 2, Phase 3·Recruiting·Listed Oct 2025
Apply to this trial

Top Research Study Locations in Iowa City

Researchers run research studies in Iowa City, IA at 25 active sites. The clinics below currently host the largest number of recruiting studies — each name is followed by the conditions they focus on most.

SiteSpecializes inActive trials
University of IowaHearing Loss, Sensorineural, Multiple Myeloma, Cystic Fibrosis190
University of Iowa/Holden Comprehensive Cancer CenterAcute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, B Acute Lymphoblastic Leukemia71
University of Iowa Hospitals and ClinicsAtrial Fibrillation, Carrier State, Chronic Lymphocytic Leukemia55
University of Iowa Health CareCOVID-19, Glioblastoma, Major Depression43
University of Iowa Hospitals & ClinicsAML With Mutated NPM1, Acute Myeloid Leukemia, Hematologic Malignancy20
University of Iowa Hospital and ClinicsOvarian Cancer, Acute Myeloid Leukaemia (AML), Anesthesia10
University of Iowa Stead Family Children's HospitalAcute Myeloid Leukemia, Anesthesia, Cardiac Arrest7
Iowa City VA Health Care System, Iowa City, IAChronic Kidney Disease, Atherosclerosis, End-Stage Kidney Disease5
The University of IowaImmune Thrombocytopenic Purpura (ITP), Abdominal Abscess, Attention Deficit Disorder With Hyperactivity (ADHD)4
University of Iowa Children's HospitalAtrial Arrhythmia, Atrial Tachycardia, Congenital Heart Disease4
University of Iowa HospitalAcute Kidney Injury, Acute Leukemia of Ambiguous Lineage, Acute Lymphoblastic Leukemia4
Clinical Trial SiteATTR Amyloidosis, Generalized Myasthenia Gravis, Hereditary Transthyretin-mediated (hATTR) Amyloidosis3
Holden Comprehensive Cancer CenterAstrocytoma, IDH-Mutant, Grade 4, Diffuse Hemispheric Glioma, H3 G34-Mutant, Diffuse Midline Glioma (DMG)3
Integrative Laboratory of Applied Physiology and Lifestyle MedicineAdverse Childhood Experiences, Endothelial Dysfunction, Oxidative Stress3
University of Iowa Carver College of MedicineDelirium, Depression, Early Onset Hereditary Spastic Paraplegia3
University of Iowa College of Dentistry and Dental ClinicsDental Pulp Necroses, Gingival Recession, Wound Healing3
University of Iowa HealthcareCardiovascular Diseases, Cochlear Implantation, Cognitive Impairment, Mild3
University of Iowa Medical CenterAtrial Fibrillation, Coronary Artery Disease, Intracerebral Hemorrhage3
89bio Clinical Study SiteMetabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis, Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis2
Ascendis Investigational SiteGrowth Hormone Deficiency2
GSK Investigational SiteGastrointestinal Neoplasms, Neoplasms, Head and Neck2
Iowa Bioscience Innovation FacilityElectronic Cigarette Use, Endothelial Dysfunction, Gestational Diabetes Mellitus (GDM)2
Research FacilityCarcinoid, Carcinoid Tumor, GEP-NET2
Stead Family Children's HospitalCardiac Arrest (CA), Deep Venous Thrombosis2
The University of Iowa Hospitals & ClinicsCrohn's Disease, Primary Immune Thrombocytopenia (ITP)2

Active & Upcoming Studies in Iowa City (2026)

Recruiting trials in Iowa City grouped by therapeutic area, drawn from ClinicalTrials.gov. Each bucket shows the most recent example studies.

Cancer & tumors (176 active studies)

Neurology & pain (33 active studies)

Cardiovascular (28 active studies)

Diabetes & metabolic (18 active studies)

Mental health & behavior (11 active studies)

Pediatric (9 active studies)

Vaccines (4 active studies)

Eye & vision (2 active studies)

HIV / STI (1 active study)

Common conditions studied in Iowa City

Leading research sponsors in Iowa City

  • University of Iowa
  • National Cancer Institute (NCI)
  • Children's Oncology Group
  • Novartis Pharmaceuticals
  • Anna Stanhewicz, PhD

Frequently asked questions

How many paid clinical trials are currently recruiting in Iowa City?

There are approximately 554 recruiting clinical trials in Iowa City, Iowa listed on ClinicalTrials.gov. The number changes weekly as new studies open and others close enrollment.

Do clinical trials in Iowa City pay participants?

Most recruiting trials in Iowa City compensate participants for their time, travel, and study visits. Compensation varies by sponsor, study phase, and visit requirements — the exact amount is disclosed by the study team during the informed consent process.

Who can participate in a clinical trial in Iowa City?

Eligibility depends on the specific study. Each trial defines its own inclusion criteria (age, diagnosis, medical history, prior treatments) and exclusion criteria. Both patients with specific conditions and healthy volunteers can qualify, depending on the study design.

What conditions are most commonly studied in Iowa City?

The most common conditions under active study in Iowa City include Acute Myeloid Leukemia (11), Breast Cancer (10), Multiple Myeloma (8), Hearing Loss, Sensorineural (5), among many others. Browse the list above to explore every recruiting trial.

Are there clinical trials for healthy volunteers in Iowa City?

Yes. Healthy-volunteer studies — often early-phase pharmacology or vaccine trials — recruit in Iowa City on an ongoing basis. Use the "Healthy volunteers only" filter above to view trials that accept participants without the study's target condition.

How do I enroll in a clinical trial in Iowa City?

Click any study title above to see the full study record, including eligibility criteria, visit schedule, and the study team's contact information. Reach out to the central contact or recruiting site directly — they will guide you through screening and informed consent.

Where can I take part in paid clinical trials in Iowa City?

Recruiting research sites in Iowa City include University of Iowa, University of Iowa/Holden Comprehensive Cancer Center, University of Iowa Hospitals and Clinics, among others. Each site lists its open studies and contact information on the study record above — call or email the site coordinator to ask about screening for a specific protocol.

What kinds of studies are recruiting in Iowa City right now?

The largest active categories in Iowa City are Cancer & tumors (176), Neurology & pain (33), Cardiovascular (28). Use the filters above to narrow by therapeutic area, phase, age, or healthy-volunteer eligibility.

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Related healthcare resources in Iowa

Latest Iowa City, IA clinical trials research report

Trials by condition in Iowa City

Acute Myeloid Leukemia· 11Breast Cancer· 10Multiple Myeloma· 8Non-Hodgkin Lymphoma· 5Stroke· 5Atrial Fibrillation· 4Bladder Cancer· 4