Paid Clinical Trials in Iowa City, IA

As of June 2026, 592 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 29, 2026.

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592 clinical trials

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Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer

for Extensive Stage Lung Small Cell Carcinoma

Drug: Atezolizumab

5 locations incl. Chicago

Sponsor: Dwight Owen

Sex: All·Age: 18+

Code: NCT04919382·Phase 2·Recruiting

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COVID-19 Coagulopathy Extension Study

for COVID-19

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 99

Code: NCT05334615·Recruiting

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Proact: A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease

for Type 2 Diabetes Mellitus

79 locations incl. Huntsville

Sponsor: Prokidney

Sex: All·Age: 30 - 80

Code: NCT05099770·Phase 3·Recruiting

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The Effects of the CF Carrier State on the Kidneys and Pancreas

for Carrier State

1 location in Iowa City

Sponsor: Philip Polgreen

Sex: All·Age: 18 - 100

Code: NCT05474417·Recruiting

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Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity

for Carrier State

1 location in Iowa City

Sponsor: Philip Polgreen

Sex: All·Age: 18 - 100

Code: NCT05474430·Recruiting

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Long-term Follow-up Study for Participants of Kite-Sponsored Interventional Studies Treated With Gene-Modified Cells

for Solid and Hematological Malignancies

49 locations incl. Gilbert

Sponsor: Kite, A Gilead Company

Sex: All·Age: All ages

Code: NCT05041309·Enrolling By Invitation

Autoimmune Intervention Mastery Course Study

for Multiple Sclerosis

1 location in Iowa City

Sponsor: Terry L. Wahls

Sex: All·Age: 18 - 100

Code: NCT05057676·Recruiting

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Open-Label Extension Study of Marstacimab in Hemophilia Participants With or Without Inhibitors

for Hemophilia A

4 locations incl. Iowa City

Sponsor: Pfizer

Sex: Male·Age: 1 - 74

Code: NCT05145127·Phase 3·Recruiting

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Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer

for Renal Pelvis and Ureter Urothelial Carcinoma

Drug: Durvalumab

258 locations incl. Kingman

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04628767·Phase 2, Phase 3·Recruiting

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Ceribell Delirium Data Collection Study

for Delirium

7 locations incl. Stanford

Sponsor: Ceribell Inc.

Sex: All·Age: 18+

Code: NCT04962815·Recruiting

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American Lung Association (ALA) Lung Health Cohort

for Lung Diseases

37 locations incl. Birmingham

Sponsor: Johns Hopkins University

Sex: All·Age: 25 - 35·Accepts healthy volunteers

Code: NCT04543461·Recruiting

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

44 locations incl. Coronado

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting

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JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

29 locations incl. Huntsville

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting

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A Dose-Escalation and Expansion Study of BGB-16673 in Participants With B-Cell Malignancies

for B-cell Malignancy

31 locations incl. Birmingham

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT05006716·Phase 1, Phase 2·Recruiting

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SPIROMICS Study of Early COPD Progression (SOURCE)

for COPD, Early-Onset

14 locations incl. Birmingham

Sponsor: University of Massachusetts, Worcester

Sex: All·Age: 30 - 55·Accepts healthy volunteers

Code: NCT05033990·Recruiting

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A Comparison Of Primary TKA Rehabilitation Using A Smart Orthotic Versus Outpatient Physical Therapy

for Arthropathy of Knee

1 location in Iowa City

Sponsor: Nicolas Noiseux, MD, MS, FRCSC

Sex: All·Age: 18 - 100

Code: NCT04924205·Recruiting

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Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy

for Congenital Myotonic Dystrophy

10 locations incl. Little Rock

Sponsor: AMO Pharma Limited

Sex: All·Age: 6 - 45

Code: NCT05004129·Phase 2, Phase 3·Recruiting

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Evaluation of Lymphoma Prognosis and Survivorship in Recently Diagnosed Patients, LEO Study

for Lymphoma, Non-Hodgkin

12 locations incl. Scottsdale

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04996706·Enrolling By Invitation

Long-Term Follow-up of Subjects Who Were Treated With ST-920

for Fabry Disease

8 locations incl. Irvine

Sponsor: Sangamo Therapeutics

Sex: All·Age: 18+

Code: NCT05039866·Enrolling By Invitation

Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)

for Pheochromocytoma/Paraganglioma

14 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 12+

Code: NCT04924075·Phase 2·Recruiting

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Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

for Focal Segmental Glomerulosclerosis

Drug: Sparsentan

23 locations incl. Los Angeles

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 17

Code: NCT05003986·Phase 2·Recruiting

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A Study of 177Lu-FAP-2286 in Advanced Solid Tumors

for Solid Tumor

20 locations incl. Birmingham

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04939610·Phase 1, Phase 2·Recruiting

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Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

for C3G

Drug: Iptacopan

13 locations incl. Aurora

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 12 - 60

Code: NCT04817618·Phase 3·Recruiting

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Biorepository and Registry for Plasma Exchange Patients

for Antibody-mediated Rejection

1 location in Iowa City

Sponsor: Charles M Knudson

Sex: All·Age: 12 - 99

Code: NCT05004493·Recruiting

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Registry of Arthrex Hand and Wrist Products

for Ulnar/Radial Collateral Ligament Reconstruction

5 locations incl. Phoenix

Sponsor: Arthrex, Inc.

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05046600·Recruiting

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A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT

for Central Nervous System Nongerminomatous Germ Cell Tumor

149 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 3 - 29

Code: NCT04684368·Phase 2·Recruiting

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CureDuchenne Link®: A Resource for Research

for Duchenne Muscular Dystrophy

10 locations incl. Little Rock

Sponsor: CureDuchenne

Sex: All·Age: 4 Weeks+

Code: NCT04972604·Recruiting

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A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

for Cervical Cancer

11 locations incl. Clovis

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT04895709·Phase 1, Phase 2·Recruiting

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Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer

Drug: Durvalumab

5 locations incl. Chicago

Sponsor: Muhammad Furqan

Sex: All·Age: 18+

Code: NCT04699838·Phase 2·Recruiting

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Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

for Chronic Pancreatitis

22 locations incl. Los Angeles

Sponsor: M.D. Anderson Cancer Center

Sex: All·Age: Up to 17

Code: NCT06651580·Recruiting

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Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on RecoverY

for Ischemic Stroke

31 locations incl. Phoenix

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT04916210·Recruiting

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Genetic Epidemiology of Rotator Cuff Tears: The cuffGEN Study

for Rotator Cuff Tears

10 locations incl. Iowa City

Sponsor: University of Michigan

Sex: All·Age: 40 - 85

Code: NCT04831164·Recruiting

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Single-Sided Deafness and Asymmetric Hearing Loss

for Hearing Loss, Unilateral

5 locations incl. Chicago

Sponsor: Med-El Corporation

Sex: All·Age: 5+

Code: NCT04506853·Recruiting

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ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment (ASCEND)

for Acute Respiratory Distress Syndrome

76 locations incl. Birmingham

Sponsor: University of Michigan

Sex: All·Age: 14 Days - 20

Code: NCT05388708·Recruiting

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Beat Childhood Cancer Specimen Banking and Data Registry

for Pediatric Cancer

18 locations incl. Little Rock

Sponsor: Giselle Sholler

Sex: All·Age: All ages·Accepts healthy volunteers

Code: NCT04715178·Recruiting

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The Biomarkers in the Hyperbaric Oxygen Brain Injury Treatment Trial (BioHOBIT)

for Traumatic Brain Injury

10 locations incl. San Diego

Sponsor: University of Michigan

Sex: All·Age: 16 - 65

Code: NCT04855396·Recruiting

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A Trial to Find Out How Safe REGN7075 is and How Well it Works in Combination With Cemiplimab for Adult Participants With Advanced Cancers

for Advanced Solid Tumors

Drug: Cemiplimab

21 locations incl. Los Angeles

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 18+

Code: NCT04626635·Phase 1, Phase 2·Recruiting

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

54 locations incl. Birmingham

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting

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A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)

for Down Syndrome

Drug: Nivolumab

209 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 1 - 30

Code: NCT04546399·Phase 2·Recruiting

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Motor Outcomes to Validate Evaluations in FSHD (MOVE FSHD)

for FSHD

16 locations incl. Los Angeles

Sponsor: University of Kansas Medical Center

Sex: All·Age: All ages

Code: NCT04635891·Recruiting

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