Paid Clinical Trials in Iowa City, IA

As of August 2026, 554 paid clinical trials are recruiting in Iowa City, Iowa. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 13, 2026.

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Healthy volunteers only

510 clinical trials

Smartphone Flicker Fusion Test for Patients With Optic Disorders.

for Scotoma

1 location in Iowa City

Sponsor: Randy Kardon

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03475147·Recruiting·Listed Mar 2018

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New Non-invasive Modalities for Assessing Retinal Structure and Function

for Ischemic Optic Neuropathy

1 location in Iowa City

Sponsor: Randy Kardon

Sex: All·Age: 18 - 99·Accepts healthy volunteers

Code: NCT03475173·Recruiting·Listed Mar 2018

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Objectively Diagnose and Monitor Treatment of Light Sensitivity

for Photophobia

1 location in Iowa City

Sponsor: Randy Kardon

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03694626·Recruiting·Listed Oct 2018

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Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity

for Adverse Childhood Experience

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 29·Accepts healthy volunteers

Code: NCT07244809·Recruiting·Listed Nov 2025

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Prenatal Aspirin and Postpartum Vascular Function

for Preeclampsia

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50·Accepts healthy volunteers

Code: NCT05653973·EARLY_Phase 1·Recruiting·Listed Dec 2022

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Barriers and Facilitators to OTC Hearing Aids Success

for Hearing Loss, Sensorineural

Sites in Iowa City +1 more location

Sponsor: Yu-Hsiang Wu

Sex: All·Age: 18 - 89

Code: NCT06499805·Recruiting·Listed Jul 2024

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Biorepository and Registry for Plasma Exchange Patients

for Antibody-mediated Rejection

1 location in Iowa City

Sponsor: Charles M Knudson

Sex: All·Age: 12 - 99

Code: NCT05004493·Recruiting·Listed Aug 2021

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Metformin for the Treatment of Microvascular Dysfunction After Gestational Diabetes

for Gestational Diabetes

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05917587·EARLY_Phase 1·Recruiting·Listed Jun 2023

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Ramucirumab and Paclitaxel or FOLFIRI in Advanced Small Bowel Cancers

for Metastatic Small Intestinal Adenocarcinoma

Sites in Iowa City, Bettendorf +397 more locations

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT04205968·Phase 2·Recruiting·Listed Dec 2019

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Home-Based Monitoring in Parkinson's Disease

for Parkinson Disease

1 location in Iowa City

Sponsor: Jacob E. Simmering

Sex: All·Age: 50 - 110

Code: NCT06573762·Recruiting·Listed Aug 2024

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Preventing Injured Knees From osteoArthritis: Severity Outcomes

for Osteoarthritis, Knee

Sites in Iowa City +8 more locations

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 45

Code: NCT06096259·Phase 2·Recruiting·Listed Oct 2023

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Outcomes of Limited Postoperative Restrictions Following Sling Placement: A Randomized Controlled Trial

for Postoperative Restriction

1 location in Iowa City

Sponsor: University of Iowa

Sex: Female·Age: 18 - 99

Code: NCT06840093·Recruiting·Listed Feb 2025

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Characterizing the Impact of Presbyphonia on Social Interaction

for Presbyphonia

1 location in Iowa City

Sponsor: Matthew R. Hoffman

Sex: All·Age: 65+

Code: NCT06441136·Recruiting·Listed Jun 2024

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Stimulant Effects on Disruptive Behavior

for Attention Deficit Hyperactivity Disorder

1 location in Iowa City

Sponsor: Matthew J O'Brien, PhD, BCBA-D

Sex: All·Age: 48 Months - 12·Accepts healthy volunteers

Code: NCT03420339·Phase 4·Recruiting·Listed Feb 2018

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Can PLIA Reduce Early Post-operative Pain After PAO Surgery?

for Hip Dysplasia

1 location in Iowa City

Sponsor: Michael C Willey

Sex: All·Age: 13 - 50·Accepts healthy volunteers

Code: NCT06519955·Phase 2, Phase 3·Recruiting·Listed Jul 2024

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Essential Amino Acid Supplementation for Femoral Fragility Fractures

for Femoral Fracture

Sites in Iowa City +1 more location

Sponsor: Michael C Willey

Sex: All·Age: 65+

Code: NCT06050668·Phase 2·Recruiting·Listed Sep 2023

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Spastic Paraplegia - Centers of Excellence Research Network

for Hereditary Spastic Paraplegia

Sites in Iowa City +10 more locations

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06553976·Recruiting·Listed Aug 2024

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Intravenous Ascorbate Plus Gemcitabine/Carboplatin: A Novel and Cost-Effective Alternative With Evident Efficacy in Patients With Muscle Invasive Bladder Cancer

for Bladder Cancer

Sites in Iowa City +1 more location

Sponsor: University of Kansas Medical Center

Sex: All·Age: 18+

Code: NCT06493370·Phase 2·Recruiting·Listed Jul 2024

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VOICE-Early Response to Vedolizumab and IL-23 Antagonists in Participants With Crohn's Disease: A Prospective Observational Study

for Crohn's Disease

Sites in Iowa City +10 more locations

Sponsor: Alimentiv Inc.

Sex: All·Age: 18+

Code: NCT06249555·Recruiting·Listed Feb 2024

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Pulmonary Hypertension Association Registry

for Pulmonary Arterial Hypertension

Sites in Iowa City +51 more locations

Sponsor: Pulmonary Hypertension Association, Inc.

Sex: All·Age: 0+

Code: NCT04071327·Recruiting·Listed Aug 2019

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The Effects of the CF Carrier State on the Kidneys and Pancreas

for Carrier State

1 location in Iowa City

Sponsor: Philip Polgreen

Sex: All·Age: 18 - 100

Code: NCT05474417·Recruiting·Listed Jul 2022

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Estimating Risk of Respiratory Infections Attributable to CFTR Heterozygosity

for Carrier State

1 location in Iowa City

Sponsor: Philip Polgreen

Sex: All·Age: 18 - 100

Code: NCT05474430·Recruiting·Listed Jul 2022

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Parkinson's Foundation PD GENEration Genetic Registry

for Parkinson's Disease

Sites in Iowa City +52 more locations

Sponsor: Parkinson's Foundation

Sex: All·Age: 18+

Code: NCT04994015·Recruiting·Listed Aug 2021

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The Effects of Heel Distraction Height on Foot Loading With Carbon Fiber Custom Dynamic Orthoses

for Traumatic Lower Limb Injury

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 65

Code: NCT06127316·Recruiting·Listed Nov 2023

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Diabetic Foot Ulcer Imaging- Study 2

for Foot Ulcer

1 location in Iowa City

Sponsor: Linnea Polgreen

Sex: All·Age: 21 - 100

Code: NCT03942081·Recruiting·Listed May 2019

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Role of Inflammation in Vascular Phenotype Associated With E-cigarette Use

for Electronic Cigarette Use

2 locations in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 24·Accepts healthy volunteers

Code: NCT06489249·EARLY_Phase 1·Recruiting·Listed Jul 2024

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Daily Aspirin Treatment After Preeclampsia

for Preeclampsia

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 50

Code: NCT06168461·EARLY_Phase 1·Recruiting·Listed Dec 2023

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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

for Hypoplastic Left Heart Syndrome (HLHS)

Sites in Iowa City +58 more locations

Sponsor: Children's Hospital Medical Center, Cincinnati

Sex: All·Age: Up to 15 Months

Code: NCT02852031·Recruiting·Listed Aug 2016

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Limited-duration Teclistamab

for Myeloma Multiple

Drug: Teclistamab

Sites in Iowa City +4 more locations

Sponsor: Abramson Cancer Center at Penn Medicine

Sex: All·Age: 18+

Code: NCT05932680·Phase 2·Recruiting·Listed Jul 2023

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E-Tailored Pain Management Support for Dementia Family Caregivers: Feasibility of the PACE-app

for Care Giving Burden

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 100·Accepts healthy volunteers

Code: NCT07032350·Recruiting·Listed Jun 2025

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Comparing Approaches to Assess Nitric Oxide-dependent Cutaneous Vasodilation

for Endothelial Function

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 30·Accepts healthy volunteers

Code: NCT06499844·EARLY_Phase 1·Recruiting·Listed Jul 2024

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Sensitivity of Angiotensin II Type II Receptors in Women Following Preeclampsia

for Preeclampsia Postpartum

1 location in Iowa City

Sponsor: Anna Stanhewicz, PhD

Sex: Female·Age: 18 - 45·Accepts healthy volunteers

Code: NCT05937841·EARLY_Phase 1·Recruiting·Listed Jul 2023

Apply to this trial

Acceptance and Commitment Therapy for Patients Undergoing Coronary Artery Bypass Graft Surgery

for Coronary Artery Disease

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 80

Code: NCT06207318·Recruiting·Listed Jan 2024

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Oxytocin and Fetal Heart Rate Changes

for Fetal Bradycardia Complicating Labor and Delivery

Sites in Iowa City +1 more location

Sponsor: Unyime Ituk

Sex: Female·Age: 18 - 55·Accepts healthy volunteers

Code: NCT03232918·Phase 4·Recruiting·Listed Jul 2017

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Preop Laxatives in Robotic Urologic Surgery

for Prostate Cancer

1 location in Iowa City

Sponsor: Chad R. Tracy

Sex: All·Age: 30 - 100·Accepts healthy volunteers

Code: NCT05805436·Phase 4·Recruiting·Listed Apr 2023

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COVID-19 Coagulopathy Extension Study

for COVID-19

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 18 - 99

Code: NCT05334615·Recruiting·Listed Apr 2022

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Language Outcomes, Mechanisms, and Trajectories in Adults With and Without Developmental Language Disorder

for Developmental Language Disorder

1 location in Iowa City

Sponsor: University of Iowa

Sex: All·Age: 30 - 35·Accepts healthy volunteers

Code: NCT06898671·Recruiting·Listed Mar 2025

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Disease Modifying Potential of 5mg of Melatonin on Cognition and Brain Health in Aging

for Mild Cognitive Impairment

1 location in Iowa City

Sponsor: Natalie Denburg

Sex: All·Age: 56 - 85·Accepts healthy volunteers

Code: NCT03954899·Recruiting·Listed May 2019

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Vertebral Artery Origin Treatment Via Endovascular Techniques Registry (VOTER)

for Vertebral Artery Stenosis

Sites in Iowa City +9 more locations

Sponsor: St. Louis University

Sex: All·Age: 18 - 90

Code: NCT03999983·Recruiting·Listed Jun 2019

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Antibiotic Irrigations for Intra-Abdominal Drains

for Abdominal Abscess

1 location in Iowa City

Sponsor: Paolo Goffredo

Sex: All·Age: 18 - 80·Accepts healthy volunteers

Code: NCT03476941·Phase 2·Recruiting·Listed Mar 2018

Apply to this trial