Clinical Trials at Mayo Clinic in Florida

As of August 2026, 142 paid clinical trials are recruiting at Mayo Clinic in Florida, located at 4500 SAN PABLO RD S, JACKSONVILLE, FL 32224-1865, phone (904) 953-2000 in Jacksonville, Florida. Compensation typically covers time, travel, and study visits — most studies also offer study-related medical care at no cost to participants.

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Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 27, 2026.

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144 clinical trials at Mayo Clinic in Florida

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Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform

for Early Stage Triple-Negative Breast Carcinoma

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06349642·Recruiting·Listed Apr 2024

Apply to this trial

Collecting Medical Information and Tissue Samples From Patients With Pancreatic Cancer or Other Pancreatic Disorders

for Islet Cell Tumor

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT00830557·Recruiting·Listed Jan 2009

Apply to this trial

A Vaccine (H2NVAC) Before Surgery for the Treatment of HER2-Expressing Ductal Carcinoma In Situ

for Breast Ductal Carcinoma In Situ

Sites in Jacksonville +1 more location

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT04144023·Phase 1·Recruiting·Listed Oct 2019

Apply to this trial

Knee Injections for Obese Patients With Knee Arthritis

for Osteoarthritis of Knee

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 55 - 85

Code: NCT06782529·Phase 4·Recruiting·Listed Jan 2025

Apply to this trial

Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC

for Pancreas Cancer

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04605913·Phase 1, Phase 2·Recruiting·Listed Oct 2020

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B-Cell Activating Factor Receptor (BAFFR)-Based Chimeric Antigen Receptor T-Cells With Fludarabine and Cyclophosphamide Lymphodepletion for the Treatment of Relapsed or Refractory B-cell Hematologic Malignancies

for B-Cell Non-Hodgkin Lymphoma

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06191887·Phase 1·Recruiting·Listed Jan 2024

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Shared Decision Making to Improve Goals of Care in the ED

for Goals

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 60+

Code: NCT03833622·Recruiting·Listed Feb 2019

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Lung Ultrasound Artefact Analysis for Exclusion of Acute Rejection in Lung Transplant Recipients

for Post-Lung Transplantation Bronchiectasis

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04582279·Recruiting·Listed Oct 2020

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Study of Human Brain-Gut Axis and Gut Microbiome in Patients With Brain Lesions - Repository for Neuroscience Research

for Malignant Central Nervous System Neoplasm

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06117930·Recruiting·Listed Nov 2023

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Golcadomide and Rituximab as Bridging Therapy for Relapsed or Refractory Aggressive B-cell Non-Hodgkin Lymphoma Before CAR T-cell Therapy

for Large B-Cell Lymphoma With IRF4 Rearrangement

Drug: Golcadomide

Sites in Jacksonville +6 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06834373·Phase 2·Recruiting·Listed Feb 2025

Apply to this trial

Functional Dyspepsia Treatment Using Virtual Reality

for Functional Dyspepsia

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18 - 75

Code: NCT05836597·Recruiting·Listed May 2023

Apply to this trial

Building Community Living Labs in Black Communities to Advance Prostate Health Equity and Reduce Prostate Cancer Disparities in Black Men

for Prostate Carcinoma

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 21 - 80·Accepts healthy volunteers

Code: NCT06541210·Recruiting·Listed Aug 2024

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Effect of Inspiratory Muscle Training on Physiological Function and Clinical Outcomes After Lung Transplant

for Post-Lung Transplantation Bronchiectasis

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT04783155·Recruiting·Listed Mar 2021

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Biospecimen Biorepository for the Study of ALS, ALS-FTD and Similar Neurodegenerative Disorders

for Amyotrophic Lateral Sclerosis

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT05116943·Recruiting·Listed Nov 2021

Apply to this trial

Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma

for Cutaneous Melanoma, Stage II

Sites in Jacksonville, Lakeland +128 more locations

Sponsor: Melanoma and Skin Cancer Trials Limited

Sex: All·Age: 18+

Code: NCT03860883·Recruiting·Listed Mar 2019

Apply to this trial

Globus Pallidus Stimulation to Treat Insomnia

for Parkinson Disease

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: All·Age: 40 - 80

Code: NCT04116996·Recruiting·Listed Oct 2019

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Understanding of Genetics by Men at Risk for Prostate Cancer

for Prostate Cancer

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: Male·Age: 40 - 95·Accepts healthy volunteers

Code: NCT04550845·Recruiting·Listed Sep 2020

Apply to this trial

Avacopan in Crescentic Immunoglobulin A Nephropathy (IgAN)

for IgA Nephropathy (IgAN)

Sites in Jacksonville +1 more location

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT06676579·Phase 2·Recruiting·Listed Nov 2024

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Folate Receptor Alpha Dendritic Cells (FRαDCs) or Placebo for the Treatment of Patients With Stage III or IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer, FAROUT Trial

for Advanced Fallopian Tube Carcinoma

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: Female·Age: 18+

Code: NCT06639074·Phase 2·Recruiting·Listed Oct 2024

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Pre-myeloid Cancer and Bone Marrow Failure Clinic Study

for Myeloid Malignancy

Sites in Jacksonville +2 more locations

Sponsor: Mayo Clinic

Sex: All·Age: 18+

Code: NCT02958462·Recruiting·Listed Nov 2016

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Feasibility of Patient-Centered Home Care (PCHC) to Reduce Disparities in High-Risk Black Men (BM) With Prostate Cancer (CaP)

for Prostate Adenocarcinoma

1 location in Jacksonville

Sponsor: Mayo Clinic

Sex: Male·Age: 18+·Accepts healthy volunteers

Code: NCT06470750·Recruiting·Listed Jun 2024

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Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer

for Clinical Stage III Gastric Cancer AJCC v8

Sites in Jacksonville, Weston +6 more locations

Sponsor: Academic and Community Cancer Research United

Sex: All·Age: 18+

Code: NCT04660760·Phase 2·Recruiting·Listed Dec 2020

Apply to this trial