Paid Clinical Trials in Kentucky

Kentucky has 961 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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871 clinical trials

Fibromyalgia Response With Esreboxetine Evaluated Using a Randomized Withdrawal Research Design

for Fibromyalgia

Sites in Louisville +50 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07398417·Phase 3·Recruiting·Listed Feb 2026

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A Study of YL201 in Combination With Other Anti-Cancer Therapies in Patients With Advanced Solid Tumors

for Thoracic Neoplasms, Lung Diseases, Small Cell Lung Carcinoma

Sites in Louisville +3 more locations

Sponsor: MediLink Therapeutics (Suzhou) Co., Ltd.

Sex: All·Age: 18+

Code: NCT07407933·Phase 1, Phase 2·Recruiting·Listed Feb 2026

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A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

for Relapsed Refractory Multiple Myeloma

Sites in Louisville +33 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07391657·Phase 3·Recruiting·Listed Feb 2026

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An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

Sites in Louisville, Lexington +28 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Recruiting·Listed Jan 2026

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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma

for Eosinophilic Asthma

Sites in Louisville +26 more locations

Sponsor: Kymera Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07323654·Phase 2·Recruiting·Listed Jan 2026

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ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults

for Asthma

Sites in Owensboro +17 more locations

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07301255·Phase 2·Recruiting·Listed Dec 2025

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Study of ENV-294 in Adults With Moderate-to-Severe Atopic Dermatitis

for Atopic Dermatitis (AD)

Sites in Louisville +31 more locations

Sponsor: Enveda Therapeutics

Sex: All·Age: 18 - 75

Code: NCT07298395·Phase 2·Recruiting·Listed Dec 2025

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Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for Clostridioides Difficile Infection

Sites in Louisville, Lexington +32 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07285213·Phase 2·Recruiting·Listed Dec 2025

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Louisville +47 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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Animal Assisted Therapy

for Anxiety

1 location in Lexington

Sponsor: Andrew Bernard

Sex: All·Age: 4 - 99

Code: NCT07227181·Recruiting·Listed Nov 2025

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Louisville +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025

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AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for Epithelial Ovarian Cancer

Sites in Louisville +38 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07218809·Phase 3·Recruiting·Listed Oct 2025

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A Phase 2b Study Evaluating Oral VH4524184 Regimens in Treatment Naïve Persons With HIV-1 (INNOVATE Study)

for HIV Infections

Sites in Louisville +34 more locations

Sponsor: ViiV Healthcare

Sex: All·Age: 18+

Code: NCT07202546·Phase 2·Recruiting·Listed Oct 2025

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eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

for Pulmonary Disease, Chronic Obstructive

Drug: Depemokimab

Sites in Bowling Green +41 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 40 - 75

Code: NCT07177339·Phase 3·Recruiting·Listed Sep 2025

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A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of MBX 4291 in Adult Participants With Obesity

for Obesity

Sites in Lexington +3 more locations

Sponsor: MBX Biosciences

Sex: All·Age: 18 - 65

Code: NCT07142707·Phase 1·Recruiting·Listed Aug 2025

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Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: IMVT-1402

Sites in Lexington, Nicholasville +46 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 80

Code: NCT07039916·Phase 3·Recruiting·Listed Jun 2025

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Imeroprubart in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

for Chronic Inflammatory Demyelinating Polyneuropathy

Sites in Nicholasville +32 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18+

Code: NCT07032662·Phase 2·Recruiting·Listed Jun 2025

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

Sites in Louisville +32 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT07018323·Phase 2·Recruiting·Listed Jun 2025

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A Long-term Safety and Efficacy Study Evaluating APG777 in Atopic Dermatitis

for Atopic Dermatitis

Sites in Bowling Green +21 more locations

Sponsor: Apogee Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07003425·Phase 2·Recruiting·Listed Jun 2025

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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids

for Asthma

Sites in Louisville +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT06932263·Phase 2·Recruiting·Listed Apr 2025

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A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

for Cardiovascular Disease

Drug: AZD0780

Sites in Lexington, Bowling Green +294 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07000357·Phase 3·Recruiting·Listed Jun 2025

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Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma

for Metastatic Clear Cell Renal Cell Carcinoma

Drug: Cabozantinib

Sites in Louisville +41 more locations

Sponsor: Arcus Biosciences, Inc.

Sex: All·Age: 18+

Code: NCT07011719·Phase 3·Recruiting·Listed Jun 2025

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A Phase 2 Study of MZE829 in Adults With APOL1 Kidney Disease

for Proteinuric Kidney Disease

Drug: MZE829

Sites in Louisville, Bowling Green +66 more locations

Sponsor: Maze Therapeutics

Sex: All·Age: 18 - 68

Code: NCT06830629·Phase 2·Recruiting·Listed Feb 2025

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Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

for Endometrial Carcinoma

Sites in Lexington, Edgewood +325 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT05256225·Phase 3·Recruiting·Listed Feb 2022

Apply to this trial

AZD0901 in Participants With Advanced Solid Tumours Expressing Claudin18.2

for Gastric Cancer

Sites in Louisville +6 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06219941·Phase 2·Recruiting·Listed Jan 2024

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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)

for Pulmonary Arterial Hypertension

Sites in Louisville +28 more locations

Sponsor: Gossamer Bio USA, Inc.

Sex: All·Age: 18 - 75

Code: NCT06274801·Phase 3·Recruiting·Listed Feb 2024

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Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

for Solid Tumor

Drug: INBRX-106

Sites in Louisville +12 more locations

Sponsor: Inhibrx Biosciences, Inc

Sex: All·Age: 18+

Code: NCT04198766·Phase 1, Phase 2·Recruiting·Listed Dec 2019

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Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis

for Ulcerative Colitis (UC)

Sites in Louisville +28 more locations

Sponsor: Xencor, Inc.

Sex: All·Age: 18 - 75·Accepts healthy volunteers

Code: NCT06619990·Phase 1, Phase 2·Recruiting·Listed Oct 2024

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Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

for Metastatic Malignant Solid Neoplasm

Sites in Lexington +17 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT05372614·Phase 1·Recruiting·Listed May 2022

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A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)

for Heart Failure

Drug: Finerenone

Sites in Louisville, Lexington +31 more locations

Sponsor: Colorado Prevention Center

Sex: All·Age: 18+

Code: NCT06024746·Phase 3·Recruiting·Listed Sep 2023

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Efficacy and Safety of Tozorakimab in Patients Hospitalised for Viral Lung Infection Requiring Supplemental Oxygen

for Viral Lung Infection and Acute Respiratory Failure

Sites in Louisville +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT05624450·Phase 3·Recruiting·Listed Nov 2022

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FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

for Metastatic Head and Neck Squamous Cell Carcinoma

Sites in Louisville +49 more locations

Sponsor: Bicara Therapeutics

Sex: All·Age: 18+

Code: NCT06788990·Phase 2, Phase 3·Recruiting·Listed Jan 2025

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A Study of Surovatamig (AZD0486) Plus Rituximab in Previously Untreated Follicular Lymphoma Patients

for Untreated Follicular Lymphoma

Drug: Rituximab

Sites in Louisville, Lexington +51 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 130

Code: NCT06549595·Phase 3·Recruiting·Listed Aug 2024

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A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma

for Asthma

Sites in Owensboro +17 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 12 - 17

Code: NCT05757102·Phase 3·Recruiting·Listed Mar 2023

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Phase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic Alterations

for Non-Small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Paducah +48 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06357533·Phase 3·Recruiting·Listed Apr 2024

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

for Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Louisville, Lexington +61 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06692738·Phase 3·Recruiting·Listed Nov 2024

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A Study to Evaluate AZD7760 Safety and Pharmacokinetics in Healthy Adults (Phase I) and Adults With End-stage Kidney Disease on Hemodialysis With a Central Venous Catheter (Phase IIa)

for Staphylococcus Aureus

Drug: AZD7760

Sites in Lexington +38 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT06749457·Phase 1, Phase 2·Recruiting·Listed Dec 2024

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A Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Non-Squamous NSCLC

for Non-squamous Non-small Cell Lung Cancer

Drug: Rilvegostomig

Sites in Louisville, Lexington +59 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT06627647·Phase 3·Recruiting·Listed Oct 2024

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Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma

for Asthma

Sites in Louisville +89 more locations

Sponsor: AstraZeneca

Sex: All·Age: 12 - 17

Code: NCT06307665·Phase 3·Recruiting·Listed Mar 2024

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A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease

for Graves' Disease

Drug: IMVT-1402

Sites in Bowling Green, Florence +56 more locations

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 75

Code: NCT06727604·Phase 2·Recruiting·Listed Dec 2024

Apply to this trial