Paid Clinical Trials in Kentucky

Kentucky has 960 paid clinical trials enrolling now across cities including Louisville, Lexington and Edgewood. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: September 14, 2026.

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875 clinical trials

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A Study to Compare the Combination of Navlimetostat (BMS-986504) With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

for Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Drug: Navlimetostat

Sites in Lexington +33 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07063745·Phase 2, Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

JAGUAR Trial: ObJective Analysis to GaUge EVAR Outcomes Through Randomization

for AAA

Sites in Louisville +24 more locations

Sponsor: Endologix

Sex: All·Age: 21+

Code: NCT05064540·Recruiting·Listed Oct 2021

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Phase 2/3 Trial of Izalontamab Brengitecan vs Platinum-based Chemotherapy for Metastatic Urothelial Cancer With Disease Progression on or After Immunotherapy

for Urothelial Cancer

Sites in Lexington +32 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07106762·Phase 2, Phase 3·Recruiting·Listed Aug 2025

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Evaluation of Efficacy and Safety of Suzetrigine for Pain Associated With Diabetic Peripheral Neuropathy

for Diabetic Peripheral Neuropathic Pain

Sites in Lexington +58 more locations

Sponsor: Vertex Pharmaceuticals Incorporated

Sex: All·Age: 18 - 80

Code: NCT06628908·Phase 3·Recruiting·Listed Oct 2024

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

Sites in Edgewood +36 more locations

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting·Listed Mar 2025

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A Study of Raludotatug Deruxtecan (R-DXd) in Subjects With Platinum-resistant, High-grade Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

for Solid Cancer

Sites in Edgewood +24 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06161025·Phase 2, Phase 3·Recruiting·Listed Dec 2023

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Study of Rondecabtagene Autoleucel in Aggressive Large B-Cell Lymphoma

for Relapsed Non-Hodgkin Lymphoma

Sites in Louisville +31 more locations

Sponsor: Lyell Immunopharma, Inc.

Sex: All·Age: 18+

Code: NCT05826535·Phase 1, Phase 2·Recruiting·Listed Apr 2023

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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

for Heart Failure With Preserved Ejection Fraction

Sites in Lexington +109 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07037459·Phase 3·Recruiting·Listed Jun 2025

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A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%

for Non-small Cell Lung Cancer

Drug: Relatlimab

Sites in Lexington, Edgewood +38 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT06561386·Phase 3·Recruiting·Listed Aug 2024

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A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)

for Type 2 Diabetes

Drug: Dulaglutide

Sites in Louisville +40 more locations

Sponsor: Eli Lilly and Company

Sex: All·Age: 10 - 17

Code: NCT06739122·Phase 3·Recruiting·Listed Dec 2024

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Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

for Metastatic Colorectal Cancer

Drug: Bevacizumab

Sites in Pikeville +10 more locations

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT06252649·Phase 3·Recruiting·Listed Feb 2024

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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

for Moderately to Severely Active Ulcerative Colitis

Drug: Afimkibart

Sites in Louisville +69 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 16 - 80

Code: NCT06588855·Phase 3·Recruiting·Listed Sep 2024

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JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

for Carcinoma, Squamous Cell

Sites in Lexington +21 more locations

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 60+

Code: NCT04892173·Phase 3·Recruiting·Listed May 2021

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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)

for Pulmonary Hypertension Due to Lung Diseases and Hypoxia

Sites in Louisville +69 more locations

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT06388421·Recruiting·Listed Apr 2024

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A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

for Crohn's Disease

Drug: TAK-279

Sites in Louisville +25 more locations

Sponsor: Takeda

Sex: All·Age: 18 - 75

Code: NCT06233461·Phase 2·Recruiting·Listed Jan 2024

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

Sites in Louisville, Lexington +38 more locations

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting·Listed Jul 2023

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A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes

for Type 1 Diabetes Mellitus

Sites in Louisville +28 more locations

Sponsor: Sanofi

Sex: All·Age: 1 - 25

Code: NCT07088068·Phase 3·Recruiting·Listed Jul 2025

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Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

for Moderate Aortic Valve Stenosis

Drug: Ataciguat

Sites in Louisville +68 more locations

Sponsor: Kardigan, Inc.

Sex: All·Age: 50+

Code: NCT07001800·Phase 2, Phase 3·Recruiting·Listed Jun 2025

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VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

for Advanced Melanoma

Drug: Nivolumab

Sites in Louisville +43 more locations

Sponsor: Replimune, Inc.

Sex: All·Age: 12+

Code: NCT06264180·Phase 3·Recruiting·Listed Feb 2024

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Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles)

for Brain Tumor, Recurrent

Sites in Louisville +50 more locations

Sponsor: GT Medical Technologies, Inc.

Sex: All·Age: All ages

Code: NCT04427384·Recruiting·Listed Jun 2020

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A Study of EPX-100 (Clemizole Hydrochloride) in Participants With Dravet Syndrome

for Dravet Syndrome

Sites in Louisville +20 more locations

Sponsor: Epygenix

Sex: All·Age: 2+

Code: NCT04462770·Phase 3·Recruiting·Listed Jul 2020

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Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure

for Heart Failure - NYHA II - IV

Sites in Louisville +39 more locations

Sponsor: Boston Scientific Corporation

Sex: All·Age: 18+

Code: NCT07069738·Recruiting·Listed Jul 2025

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A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)

for Lower Extremity Acute Limb Ischemia

Sites in Lexington +33 more locations

Sponsor: Penumbra Inc.

Sex: All·Age: 18+

Code: NCT06747117·Recruiting·Listed Dec 2024

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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease

for High Risk Cardiovascular Disease

Drug: Zilebesiran

Sites in Lexington, Bowling Green +272 more locations

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT07181109·Phase 3·Recruiting·Listed Sep 2025

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ELEVATE High-Risk PCI Pivotal Study

for High-Risk Percutaneous Coronary Intervention (High-risk PCI)

Sites in Edgewood +32 more locations

Sponsor: Magenta Medical Ltd.

Sex: All·Age: 18 - 88

Code: NCT07001332·Recruiting·Listed Jun 2025

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A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Lexington +29 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06203210·Phase 3·Recruiting·Listed Jan 2024

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A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

for Parkinsons Disease (PD)

Sites in Louisville +33 more locations

Sponsor: BlueRock Therapeutics

Sex: All·Age: 45 - 75

Code: NCT06944522·Phase 3·Recruiting·Listed Apr 2025

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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

for Progressive Pulmonary Fibrosis

Sites in Louisville, Lexington +72 more locations

Sponsor: United Therapeutics

Sex: All·Age: 18+

Code: NCT05943535·Phase 3·Recruiting·Listed Jul 2023

Apply to this trial

SELUTION 4 De Novo Small Vessel IDE Trial

for Coronary Artery Disease

Sites in Lexington +63 more locations

Sponsor: M.A. Med Alliance S.A.

Sex: All·Age: 18+

Code: NCT05946629·Recruiting·Listed Jul 2023

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ELEVATE-HFpEF Clinical Study

for Heart Failure With Preserved Ejection Fraction (HFpEF)

Sites in Louisville +25 more locations

Sponsor: Medtronic Cardiac Rhythm and Heart Failure

Sex: All·Age: 40+

Code: NCT06678841·Recruiting·Listed Nov 2024

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Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

for Crohn's Disease

Sites in Lexington +55 more locations

Sponsor: AbbVie

Sex: All·Age: 18 - 75

Code: NCT06548542·Phase 2·Recruiting·Listed Aug 2024

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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

for Pulmonary Hypertension

Sites in Lexington +36 more locations

Sponsor: Tempus AI

Sex: All·Age: 18+

Code: NCT06911632·Recruiting·Listed Apr 2025

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A Study to Assess Adverse Events and Change in Disease Activity Comparing Oral Upadacitinib to Subcutaneous Dupilumab in Children From 2 to Less Than 12 Years of Age With Moderate to Severe Atopic Dermatitis

for Atopic Dermatitis

Drug: Upadacitinib

Sites in Bowling Green +25 more locations

Sponsor: AbbVie

Sex: All·Age: 2 - 11

Code: NCT06461897·Phase 3·Recruiting·Listed Jun 2024

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Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial

for Abdominal Aortic Aneurysm

Sites in Lexington +27 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 20+

Code: NCT05378347·Recruiting·Listed May 2022

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Frankfort +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

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Neutrophil and Monocyte Deactivation Via the SeLective CytopheretIc Device - A Randomized Clinical Trial in Acute Kidney Injury

for Acute Kidney Injury

Sites in Lexington +31 more locations

Sponsor: SeaStar Medical

Sex: All·Age: 18+

Code: NCT05758077·Recruiting·Listed Mar 2023

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VE303 for Prevention of Recurrent Clostridioides Difficile Infection

for Clostridium Difficile

Sites in Louisville +55 more locations

Sponsor: Vedanta Biosciences, Inc.

Sex: All·Age: 12+

Code: NCT06237452·Phase 3·Recruiting·Listed Feb 2024

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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

for Ulcerative Colitis

Sites in Louisville +25 more locations

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07012395·Phase 2·Recruiting·Listed Jun 2025

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

Sites in Louisville +157 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting·Listed Jul 2024

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A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

for Systemic Lupus Erythematosus

Sites in Louisville +61 more locations

Sponsor: UCB Biopharma SRL

Sex: All·Age: 16+

Code: NCT06617325·Phase 3·Recruiting·Listed Sep 2024

Apply to this trial