Paid Clinical Trials in Little Rock, AR

As of August 2026, 495 paid clinical trials are recruiting in Little Rock, Arkansas. Compensation typically covers time, travel, and study visits, with stipends ranging from modest amounts for short outpatient studies to several thousand dollars for long or inpatient protocols.

Both patients with specific conditions and healthy volunteers can qualify. Most trials offer free study-related medical care alongside compensation.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: August 10, 2026.

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449 clinical trials

A Study of CREXONT (Carbidopa and Levodopa) Extended-Release Capsules in Participants With Parkinson's Disease

for Parkinson Disease

Sites in Little Rock +26 more locations

Sponsor: Impax Laboratories, LLC

Sex: All·Age: 18+

Code: NCT06765668·Phase 4·Recruiting·Listed Jan 2025

Apply to this trial

To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension

for Difficult to Control Hypertension

Sites in Little Rock +25 more locations

Sponsor: E-Star BioTech, LLC

Sex: All·Age: 18 - 80

Code: NCT06343298·Phase 2·Recruiting·Listed Apr 2024

Apply to this trial

Child and Adolescent Registry for Participants With Narcolepsy

for Narcolepsy

Sites in Little Rock, Fayetteville +23 more locations

Sponsor: Jazz Pharmaceuticals

Sex: All·Age: Up to 17

Code: NCT04899947·Recruiting·Listed May 2021

Apply to this trial

Impella RP Flex with Smart Assist

for Right Ventricular (RV) Dysfunction

Sites in Little Rock +30 more locations

Sponsor: Abiomed Inc.

Sex: All·Age: All ages

Code: NCT06637644·Recruiting·Listed Oct 2024

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Efficacy of PP-01 in Mitigating Cannabis Withdrawal Symptoms in Adults With Cannabis Use Disorder

for Cannabis Withdrawal

Sites in Little Rock, Rogers +20 more locations

Sponsor: PleoPharma, Inc.

Sex: All·Age: 18 - 55

Code: NCT07644052·Phase 3·Recruiting·Listed Jun 2026

Apply to this trial

RE104 Safety and Efficacy Study in Generalized Anxiety Disorder

for Generalized Anxiety Disorder

Sites in Little Rock +21 more locations

Sponsor: Reunion Neuroscience Inc

Sex: All·Age: 18 - 74

Code: NCT07489651·Phase 2·Recruiting·Listed Mar 2026

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DAREON ® -Lung-1: A Study in People With Advanced Small Cell Lung Cancer to Compare Obrixtamig Plus Atezolizumab, Carboplatin, and Etoposide Treatment With Standard Chemotherapy

for Small Cell Lung Cancer (SCLC)

Drug: Atezolizumab

Sites in Little Rock +16 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07472517·Phase 3·Recruiting·Listed Mar 2026

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A Study of MUC16-Directed Antibody Drug Conjugate HWK-016 in Participants With Advanced Solid Tumors.

for PROC

Sites in Little Rock +11 more locations

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07470853·Phase 1·Recruiting·Listed Mar 2026

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Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

for Endometrial Cancer

Sites in Little Rock +11 more locations

Sponsor: Whitehawk Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07444814·Phase 1·Recruiting·Listed Mar 2026

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Study to Evaluate LB-102 for the Treatment of Adult Patients With Acute Schizophrenia

for Schizophrenia

Sites in Little Rock, Bentonville +11 more locations

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07363577·Phase 3·Recruiting·Listed Jan 2026

Apply to this trial

Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)

for Hereditary Angioedema (HAE)

Sites in Little Rock +14 more locations

Sponsor: ADARx Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07428499·Phase 3·Recruiting·Listed Feb 2026

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A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

for Non-Muscle Invasive Bladder Neoplasms

Sites in Little Rock +15 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT07309445·Recruiting·Listed Dec 2025

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AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

for Corneal Edema

Sites in Little Rock +11 more locations

Sponsor: Aurion Biotech

Sex: All·Age: 18+

Code: NCT07368959·Phase 3·Recruiting·Listed Jan 2026

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A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy

for Spinal Muscular Atrophy (SMA)

Sites in Little Rock +16 more locations

Sponsor: argenx

Sex: All·Age: 5 - 17

Code: NCT07287982·Phase 2·Recruiting·Listed Dec 2025

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A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)

for Gout

Sites in Little Rock +17 more locations

Sponsor: Protalix

Sex: All·Age: 18+

Code: NCT07280156·Phase 2·Recruiting·Listed Dec 2025

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A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression

for Major Depressive Disorder (MDD)

Sites in Little Rock, Bentonville +21 more locations

Sponsor: Draig Therapeutics Ltd

Sex: All·Age: 18 - 75

Code: NCT07300969·Phase 2·Recruiting·Listed Dec 2025

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Phase 2b Study of RPT904 as Monotherapy in Participants With IgE-Mediated Food Allergy

for Ig-E Mediated Food Allergy

Drug: RPT904

Sites in Little Rock +21 more locations

Sponsor: RAPT Therapeutics, Inc.

Sex: All·Age: 12 - 55

Code: NCT07220811·Phase 2·Recruiting·Listed Oct 2025

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A Study to Evaluate the Effect of KarXT on Urological Safety

for Schizophrenia

Drug: KarXT

Sites in Little Rock +12 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07221877·Phase 4·Recruiting·Listed Oct 2025

Apply to this trial

A Study to Evaluate KYN-5356 in Adults With Cognitive Impairment Associated With Schizophrenia

for Cognitive Impairment Associated With Schizophrenia (CIAS)

Sites in Little Rock +13 more locations

Sponsor: Kynexis B.V.

Sex: All·Age: 18 - 55

Code: NCT07191483·Phase 2·Recruiting·Listed Sep 2025

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A Study to Learn About Ritlecitinib for the Potential Treatment of Chronic Spontaneous Urticaria in Adults.

for Chronic Spontaneous Urticaria

Drug: Ritlecitinib

Sites in Little Rock +14 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT07219615·Phase 2·Recruiting·Listed Oct 2025

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A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

for Mania

Drug: KarXT

Sites in Little Rock, Bentonville +18 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT07140913·Phase 3·Recruiting·Listed Aug 2025

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A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder

for Bipolar-I Disorder With Mania or Mania With Mixed Features

Drug: KarXT

Sites in Little Rock +19 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18 - 65

Code: NCT06951698·Phase 3·Recruiting·Listed Apr 2025

Apply to this trial

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder

for Bipolar 1 Disorder

Sites in Little Rock, Rogers +14 more locations

Sponsor: Rapport Therapeutics Inc.

Sex: All·Age: 18 - 65

Code: NCT07046494·Phase 2·Recruiting·Listed Jul 2025

Apply to this trial

Pembrolizumab With or Without Maintenance Sacituzumab Tirumotecan (Sac-TMT; MK-2870) in Metastatic Squamous Non-small Cell Lung Cancer (NSCLC) [MK-2870-023]

for Non-small Cell Lung Cancer

Sites in Little Rock +15 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06422143·Phase 3·Recruiting·Listed May 2024

Apply to this trial

Safety and Efficacy of APC-0101 in Preterm Infants With Respiratory Distress Syndrome

for Respiratory Distress Syndrome

Sites in Little Rock +11 more locations

Sponsor: Aerogen Pharma Limited

Sex: All·Age: 1 Hour - 24 Hours

Code: NCT06776783·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

The Ailliance Post-Market Clinical Study

for Spinal Deformity

Sites in Little Rock +22 more locations

Sponsor: Medtronic Spinal and Biologics

Sex: All·Age: 18+

Code: NCT05856370·Recruiting·Listed May 2023

Apply to this trial

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

for Dravet Syndrome

Sites in Little Rock +21 more locations

Sponsor: Longboard Pharmaceuticals

Sex: All·Age: 2 - 65

Code: NCT06660394·Phase 3·Recruiting·Listed Oct 2024

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A Phase 2 Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, in Adults and Children With PIK3CA Related Overgrowth Spectrum and Malformations Driven by PIK3CA Mutation (The ReInspire Study)

for PIK3CA-Related Overgrowth Spectrum (PROS)

Sites in Little Rock +19 more locations

Sponsor: Relay Therapeutics, Inc.

Sex: All·Age: 2+

Code: NCT06789913·Phase 2·Recruiting·Listed Jan 2025

Apply to this trial

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

for Duchenne Muscular Dystrophy

Sites in Little Rock +11 more locations

Sponsor: Solid Biosciences Inc.

Sex: Male·Age: 0 - 17

Code: NCT06138639·Phase 1, Phase 2·Recruiting·Listed Nov 2023

Apply to this trial

A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer

for Metastatic Castration-resistant Prostate Cancer

Sites in Little Rock +22 more locations

Sponsor: Syncromune, Inc.

Sex: Male·Age: 18+

Code: NCT06533644·Phase 2·Recruiting·Listed Aug 2024

Apply to this trial

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy

for Muscular Atrophy, Spinal

Sites in Little Rock +9 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Months - 24 Months

Code: NCT05861986·Phase 4·Recruiting·Listed May 2023

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A Study to Investigate the Safety and Biodistribution of a Single Intrathecal (IT) Injection of INS1201 in Ambulatory Males With Duchenne Muscular Dystrophy (DMD)

for Duchenne Muscular Dystrophy

Sites in Little Rock +9 more locations

Sponsor: Insmed Gene Therapy LLC

Sex: Male·Age: 2 - 4

Code: NCT06817382·Phase 1·Recruiting·Listed Feb 2025

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A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

for Nasopharyngeal Cancer Recurrent

Sites in Little Rock +10 more locations

Sponsor: Coherus Oncology, Inc.

Sex: All·Age: 12+

Code: NCT06457503·Phase 4·Recruiting·Listed Jun 2024

Apply to this trial

ARC-IM System to Manage Symptomatic Blood Pressure Instability Secondary to Chronic Spinal Cord Injury

for Spinal Cord Injuries

Sites in Little Rock +11 more locations

Sponsor: ONWARD Medical, Inc.

Sex: All·Age: 18 - 75

Code: NCT07147296·Recruiting·Listed Aug 2025

Apply to this trial

A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease

for Thyroid Eye Disease

Sites in Little Rock +11 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06401044·Phase 1, Phase 2·Recruiting·Listed May 2024

Apply to this trial

A Study Evaluating the Effectiveness and Safety of Risdiplam Administered in Pediatric Patients With Spinal Muscular Atrophy Who Experienced a Plateau or Decline in Function After Gene Therapy

for Muscular Atrophy, Spinal

Sites in Little Rock +8 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 3 Months - 24 Months

Code: NCT05861999·Phase 4·Recruiting·Listed May 2023

Apply to this trial

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

for Ulcerative Colitis

Sites in Little Rock +19 more locations

Sponsor: Pfizer

Sex: All·Age: 12 - 17

Code: NCT05287126·Phase 2·Recruiting·Listed Mar 2022

Apply to this trial

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

for Hematological Malignancies

Drug: Talquetamab

Sites in Little Rock +9 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT04634552·Phase 2·Recruiting·Listed Nov 2020

Apply to this trial

Open-label, Long-term Safety, Efficacy, and Pharmacokinetics Study of Vibegron in Pediatric Subjects 2 Years to < 18 Years of Age With NDO and on CIC

for Neurogenic Detrusor Overactivity

Sites in Little Rock +6 more locations

Sponsor: Urovant Sciences GmbH

Sex: All·Age: 2 - 17

Code: NCT05491525·Phase 2, Phase 3·Recruiting·Listed Aug 2022

Apply to this trial

A First-in-human Study of PARP1 Selective Inhibitor, IMP1734, in Participants With Advanced Solid Tumors

for Advanced Solid Tumor

Sites in Little Rock +13 more locations

Sponsor: Eikon Therapeutics

Sex: All·Age: 18 - 89

Code: NCT06253130·Phase 1, Phase 2·Recruiting·Listed Feb 2024

Apply to this trial