Paid Clinical Trials in Massachusetts

Massachusetts has 3,593 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 17, 2026.

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3,593 clinical trials

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Assessing Optimal XRB Initiation Points in Jail

for Opioid Use Disorder

4 locations incl. Boston

Sponsor: NYU Langone Health

Sex: Male·Age: All ages

Code: NCT06051890·Phase 4·Recruiting

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Semaglutide for Helping Opioid Recovery

for Opioid Use Disorder

Drug: Semaglutide

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06639464·Phase 2·Recruiting

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Spray Cryotherapy for the Management of Benign Central Airway Stenosis (Cryo-BAS)

for Stenosis of Trachea

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: All ages

Code: NCT06761170·Phase 2·Recruiting

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TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

for Cystic Fibrosis (CF)

13 locations incl. Orange

Sponsor: State University of New York at Buffalo

Sex: All·Age: 18 Months - 11

Code: NCT07048574·Recruiting

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Preventing T2DM After GDM With Immediate Postpartum Screening

for Gestational Diabetes

1 location in Worcester

Sponsor: University of Massachusetts, Worcester

Sex: Female·Age: 18+

Code: NCT06457139·Recruiting

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Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

for Postoperative Pain

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: Female·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06483659·Phase 2·Recruiting

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A Double Blind Study Performed to Evaluate the Efficacy and the Safety of EscharEx in Debridement of VLU (VALUE)

for Venous Leg Ulcer (VLU)

14 locations incl. Fresno

Sponsor: MediWound Ltd

Sex: All·Age: 18+

Code: NCT06568627·Phase 3·Recruiting

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Assessing Tenapanor as a Treatment of CF-related Constipation.

for Cystic Fibrosis

Drug: Tenapanor

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 75

Code: NCT06810167·Phase 3·Recruiting

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Registry and Natural History of Epilepsy-Dyskinesia Syndromes

for Epilepsy-Dyskinesia

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 0 - 30

Code: NCT06967727·Recruiting

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A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down Syndrome

for Memory Replay

1 location in Chestnut Hill

Sponsor: Boston College

Sex: All·Age: 15 - 35

Code: NCT07008989·Recruiting

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The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity

for Sleep, Inadequate

1 location in Natick

Sponsor: United States Army Research Institute of Environmental Medicine

Sex: All·Age: 17 - 39·Accepts healthy volunteers

Code: NCT06784544·Not Yet Recruiting

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

for PDAC

18 locations incl. Scottsdale

Sponsor: Tango Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06922591·Phase 1, Phase 2·Recruiting

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Tolerance Through Mixed Chimerism (Sip-Tego)

for Kidney Failure

1 location in Boston

Sponsor: Tatsuo Kawai, MD, PhD

Sex: All·Age: 18 - 65

Code: NCT06972069·EARLY_Phase 1·Recruiting

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Glucose Consumption in MS Using [F-18]FDG-PET

for Multiple Sclerosis

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 70·Accepts healthy volunteers

Code: NCT07087106·Phase 4·Recruiting

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Evaluation of a Neural-Controlled Powered Prosthesis Across Diverse Real-World Tasks

for Transfemoral Amputation

1 location in Cambridge

Sponsor: Massachusetts Institute of Technology

Sex: All·Age: 18 - 70

Code: NCT07204912·Recruiting

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A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

for B Acute Lymphoblastic Leukemia

138 locations incl. Birmingham

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 366 Days - 46

Code: NCT06124157·Phase 2·Recruiting

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Music Use in Parturients Admitted to Labor & Delivery

for Anxiety

1 location in Boston

Sponsor: Tufts Medical Center

Sex: Female·Age: 18+·Accepts healthy volunteers

Code: NCT06969105·Recruiting

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Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery

for Retroperitoneal Sarcoma

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18+

Code: NCT06812052·Phase 1·Recruiting

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A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight and Chronic Low Back Pain

for Obesity

Drug: Retatrutide

25 locations incl. Chandler

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT07035093·Phase 3·Recruiting

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A Study to Assess Adverse Events and Change in Disease Activity in Participants With Platinum-Resistant Advanced High-Grade Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancers With High Folate Receptor-Alpha Expression Treated With Intravenously (IV) Infused Mirvetuximab Soravtansine

for Advanced High-Grade Epithelial Ovarian Cancer

7 locations incl. Sarasota

Sponsor: AbbVie

Sex: Female·Age: 18+

Code: NCT06682988·Phase 2·Recruiting

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A Study to Assess the Effectiveness and Safety of Pacritinib in Patients With VEXAS Syndrome (PAXIS)

for VEXAS

Drug: Pacritinib

9 locations incl. Scottsdale

Sponsor: Swedish Orphan Biovitrum

Sex: All·Age: 18+

Code: NCT06782373·Phase 2·Recruiting

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Investigation of Ubamatamab Combination Therapy in Adult Participants With Platinum-Resistant Ovarian Cancer

for Ovarian Cancer

21 locations incl. Birmingham

Sponsor: Regeneron Pharmaceuticals

Sex: Female·Age: 18+

Code: NCT06787612·Phase 2·Recruiting

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A Study to Determine if BHV-8000 is Effective, Safe and Tolerable as a Treatment for Adults Living With Early Parkinson's Disease

for Parkinson Disease

15 locations incl. Birmingham

Sponsor: Biohaven Therapeutics Ltd.

Sex: All·Age: 40 - 85

Code: NCT06976268·Phase 2, Phase 3·Recruiting

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Treatment of UC With Novel Therapeutics

for Ulcerative Colitis Mild

1 location in Chestnut Hill

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 75

Code: NCT06420375·Phase 2·Recruiting

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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

for Ulcerative Colitis

25 locations incl. Canoga Park

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07012395·Phase 2·Recruiting

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Study to Assess the Efficacy and Safety of IMVT-1402 in Participants With Mild to Severe Generalized Myasthenia Gravis

for Generalized Myasthenia Gravis

Drug: IMVT-1402

47 locations incl. Huntsville

Sponsor: Immunovant Sciences GmbH

Sex: All·Age: 18 - 80

Code: NCT07039916·Phase 3·Recruiting

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Assessment of Circuit Rebreathing During CPAP Therapy

for Obstructive Sleep Apnea (OSA)

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 21 - 70

Code: NCT07062770·Recruiting

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A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)

for Malignant Neoplasm

17 locations incl. Los Angeles

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 1 Month - 17

Code: NCT06941272·Phase 1, Phase 2·Recruiting

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Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

for Lung Cancer (NSCLC)

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 65+

Code: NCT06987890·Recruiting

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Pleural Irrigation With a Novel Devise.

for Pleural Effusion Disorder

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06727578·Recruiting

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Small Cell Lung Cancer Community Engagement to Eliminate Research Discepancies

for Small-cell Lung Cancer

52 locations incl. Multiple Locations

Sponsor: Addario Lung Cancer Medical Institute

Sex: All·Age: 18+

Code: NCT06486428·Recruiting

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Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions

for Hypertension

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: Female·Age: 18+

Code: NCT06557005·Recruiting

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Single Use Bronchoscopes for Interventional Pulmonology

for Bronchoscopic Interventions

1 location in Boston

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06596655·Recruiting

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Glycemic Regulation as Endometriosis Adjunct Treatment

for Pelvic Pain

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: Female·Age: 15 - 35

Code: NCT06611501·Phase 2·Recruiting

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Adding the Immunotherapy Drug Cemiplimab to Usual Treatment for People With Advanced Non-Small Cell Lung Cancer Who Had Previous Treatment With Platinum Chemotherapy and Immunotherapy (An Expanded Lung-MAP Treatment Trial)

for Recurrent Lung Non-Small Cell Carcinoma

Drug: Cemiplimab

386 locations incl. Daphne

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06616584·Phase 2, Phase 3·Recruiting

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A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer

for Locally Advanced Unresectable Gastroesophageal Junction (GEJ) Adenocarcinoma or Cancer

Drug: zolbetuximab

36 locations incl. Birmingham

Sponsor: Astellas Pharma Global Development, Inc.

Sex: All·Age: 18+

Code: NCT06901531·Phase 3·Recruiting

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Minima Stent System Post- Approval Study (PAS)

for Pulmonary Artery Stenosis

15 locations incl. Los Angeles

Sponsor: Renata Medical

Sex: All·Age: All ages

Code: NCT06828770·Recruiting

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A Study to Compare Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone as Treatment in Participants With Mismatch Repair Proficient Endometrial Cancer (MK-2870-033/TroFuse-033/GOG-3119/ENGOT-en29)

for Endometrial Cancer

44 locations incl. Mobile

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT06952504·Phase 3·Recruiting

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Flotufolastat F 18 PET in Men With Very Low PSA Recurrence

for Prostate Cancer (Adenocarcinoma)

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: Male·Age: 18+

Code: NCT06862856·Recruiting

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A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

for Chronic Lymphocytic Leukemia

20 locations incl. Jacksonville

Sponsor: Eli Lilly and Company

Sex: All·Age: 18+

Code: NCT06876649·Phase 4·Recruiting

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