Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 19, 2026.

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3,602 clinical trials

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Developing a Telehealth + mHealth Cannabis Use Intervention for Young Adults

for Cannabis Use Disorder

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: 18 - 26

Code: NCT06661031·Enrolling By Invitation

Driving Inclusivity, Validity, and Equity in Research Through Strategic Engagement (DIVERSE)

for Blood Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06469307·Recruiting

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A Clinical Registry to Demonstrate the Safety and Performance of Teleflex Vascular Access Devices

for Vascular Access Device

3 locations incl. Huntsville

Sponsor: Teleflex

Sex: All·Age: All ages

Code: NCT06604039·Recruiting

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A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

for COVID-19 SARS-CoV-2 Infection

85 locations incl. Little Rock

Sponsor: Pfizer

Sex: All·Age: 12+

Code: NCT06679140·Phase 3·Recruiting

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Revumenib in Combination With 7+3 + Midostaurin in AML

for Acute Myeloid Leukemia

Drug: Revumenib

2 locations incl. New Haven

Sponsor: Richard Stone, MD

Sex: All·Age: 18 - 75

Code: NCT06313437·Phase 1·Recruiting

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Epcoritamab in Previously Treated WM

for Waldenstrom Macroglobulinemia

Drug: Epcoritamab

3 locations incl. Boston

Sponsor: Gottfried von Keudell, MD PhD

Sex: All·Age: 18+

Code: NCT06510491·Phase 2·Recruiting

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A Study of JNJ-90301900 in Combination With Chemoradiation Followed by Consolidation Immunotherapy for Non-Small Cell Lung Cancer (NSCLC)

for Carcinoma, Non-Small-Cell Lung

16 locations incl. Farmington

Sponsor: Johnson & Johnson Enterprise Innovation Inc.

Sex: All·Age: 18+

Code: NCT06667908·Phase 2·Recruiting

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Testing the mHealth App Intervention for Nondaily Smokers "SiS4"

for Smoking Cessation

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT06678243·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

39 locations incl. Little Rock

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06706674·Phase 3·Recruiting

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A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

for Recurrent Mycosis Fungoides

10 locations incl. Duarte

Sponsor: City of Hope Medical Center

Sex: All·Age: 18+

Code: NCT07003100·Recruiting

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CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial

for Chronic Pain

4 locations incl. Stanford

Sponsor: Stanford University

Sex: All·Age: 18 - 75

Code: NCT06027099·Phase 3·Recruiting

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Validation of a Novel Cerebellar-striatal Satiety Circuit in Humans

for Appetitive Behavior

2 locations incl. Belmont

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT06105164·Recruiting

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Confirmatory Trial for Alleviating Fatigue in Multiple Sclerosis

for Multiple Sclerosis

6 locations incl. Washington D.C.

Sponsor: Accelerated Cure Project for Multiple Sclerosis

Sex: All·Age: 22+

Code: NCT06441617·Recruiting

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Kidney Blood Flow During Exercise in Older African American Adults

for Healthy

1 location in Boston

Sponsor: University of Massachusetts, Boston

Sex: All·Age: 55 - 79·Accepts healthy volunteers

Code: NCT07029165·Recruiting

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A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

for Neurofibromatosis 1

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: All ages

Code: NCT06262113·Recruiting

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Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

for Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS)

9 locations incl. Denver

Sponsor: Institut de Recherches Internationales Servier

Sex: All·Age: 18+

Code: NCT06465953·Phase 3·Recruiting

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Trial of Therapeutic Cancer Vaccine OSE2101 in Patients With Non-Small Cell Lung Cancer and Secondary Resistance to Immune Checkpoint Inhibitor

for Patients With Non-Small Cell Lung Cancer

79 locations incl. Beverly Hills

Sponsor: OSE Immunotherapeutics

Sex: All·Age: 18+

Code: NCT06472245·Phase 3·Recruiting

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OurSleepKit To Support CPAP Adherence

for Obstructive Sleep Apnea

2 locations incl. Boston

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

Sex: All·Age: 18+

Code: NCT06621511·Recruiting

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A Study to Evaluate Vutrisiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

for Transthyretin Amyloidosis (ATTR) With Cardiomyopathy

24 locations incl. Phoenix

Sponsor: Alnylam Pharmaceuticals

Sex: All·Age: 18+

Code: NCT06679946·Phase 3·Enrolling By Invitation

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

for HIV Infections

41 locations incl. Birmingham

Sponsor: ViiV Healthcare

Sex: All·Age: 12+

Code: NCT06694805·Phase 3·Recruiting

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Drug Screening Using Novel IMD in Renal Cell Carcinoma

for Renal Cell Carcinoma

1 location in Boston

Sponsor: Oliver Jonas

Sex: All·Age: 18+

Code: NCT05700461·Phase 1·Recruiting

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A Study of RSLV-132 in Females With Sjögren's Disease

for Primary Sjögren Syndrome

24 locations incl. Chula Vista

Sponsor: Resolve Therapeutics

Sex: Female·Age: 18 - 75

Code: NCT06440525·Phase 2·Recruiting

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Streamlined Treatment of Pulmonary Exacerbations in Pediatrics

for Cystic Fibrosis

31 locations incl. Birmingham

Sponsor: University of Washington, the Collaborative Health Studies Coordinating Center

Sex: All·Age: 3 - 18

Code: NCT06654752·Recruiting

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Deep Brain Stimulation (DBS) MatchMaker

for TOR1A

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT06912841·Enrolling By Invitation

Integrated Treatment for Enhancing Growth in Recovery During Adolescence

for Alcohol Use Disorder

2 locations incl. Farmington

Sponsor: Massachusetts General Hospital

Sex: All·Age: 14 - 21

Code: NCT06395467·Recruiting

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Evaluation of the Safety and Effectiveness of the CereVasc® eShunt® System in Normal Pressure Hydrocephalus

for Normal Pressure Hydrocephalus

28 locations incl. Los Angeles

Sponsor: CereVasc Inc

Sex: All·Age: 60+

Code: NCT06498960·Recruiting

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BCL2i CLAG-M in R/R Acute Myeloid Leukemia

for Relapsed or Refractory Acute Myeloid Leukemia (AML)

2 locations incl. Tampa

Sponsor: H. Lee Moffitt Cancer Center and Research Institute

Sex: All·Age: 18 - 80

Code: NCT06660368·Phase 2·Recruiting

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A Phase 0 Window of Opportunity Trial of Intratumoral Seasonal Influenza Immunization in Cutaneous Squamous Cell Carcinoma (CSCC) Patients Awaiting Curative Excision

for Skin Cancer

2 locations incl. Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT06664151·EARLY_Phase 1·Recruiting

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Promoting Early Intervention Timing and Attention to Language

for MONITOR

2 locations incl. Los Angeles

Sponsor: University of California, Los Angeles

Sex: All·Age: 6 Months - 8 Months

Code: NCT05853861·Recruiting

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ADCE-T02, a Tissue Factor Targeted Antibody-Drug Conjugate, in Patients With Selected Advanced Solid Tumours

for Advanced Solid Tumor

5 locations incl. Rogers

Sponsor: Adcendo ApS

Sex: All·Age: 18+

Code: NCT06597721·Phase 1·Recruiting

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A Study of Vosoritide in Children With Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

for Noonan Syndrome

Drug: Vosoritide

22 locations incl. Los Angeles

Sponsor: BioMarin Pharmaceutical

Sex: All·Age: 3 - 11

Code: NCT06668805·Phase 2·Recruiting

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Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients

for Irritability Associated With Autism Spectrum Disorder

37 locations incl. Dothan

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 5 - 17

Code: NCT06690398·Phase 3·Recruiting

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A U.S. Registry of Eosinophilic Esophagitis Pediatric, Adolescent and Adult Patients Treated With DUPIXENT® As Standard of Care

for Eosinophilic Esophagitis (EoE)

55 locations incl. Phoenix

Sponsor: Regeneron Pharmaceuticals

Sex: All·Age: 1+

Code: NCT06693531·Recruiting

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A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

for Chronic Graft-Versus-Host Disease (cGVHD)

26 locations incl. Duarte

Sponsor: Deciphera Pharmaceuticals, LLC

Sex: All·Age: 18+

Code: NCT06619561·Phase 2·Recruiting

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A Safety and Efficacy Study of One-time SAR402663 in Adults With Neovascular Age-related Macular Degeneration

for Neovascular Age-related Macular Degeneration

18 locations incl. Phoenix

Sponsor: Sanofi

Sex: All·Age: 50 - 90

Code: NCT06660667·Phase 1, Phase 2·Recruiting

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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder

for Generalized Anxiety Disorder

30 locations incl. Birmingham

Sponsor: Intra-Cellular Therapies, Inc.

Sex: All·Age: 18+

Code: NCT06701903·Phase 2·Recruiting

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Epcoritamab in Patients With Follicular Lymphoma Not Accomplishing a CR With Upfront Chemoimmunotherapy

for Lymphoma

Drug: Epcoritamab

3 locations incl. Stanford

Sponsor: Beth Israel Deaconess Medical Center

Sex: All·Age: 18+

Code: NCT06510361·Phase 2·Recruiting

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CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

for Epithelial Ovarian Cancer

26 locations incl. Phoenix

Sponsor: TORL Biotherapeutics, LLC

Sex: Female·Age: 18+

Code: NCT06690775·Phase 2·Recruiting

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Just-in-time Interventions for Reducing Short-term Suicide Risk

for Suicide

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT05793541·Recruiting

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Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)

for Lung Non-Small Cell Carcinoma

248 locations incl. Jonesboro

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT06116682·Phase 2·Recruiting

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