Paid Clinical Trials in Massachusetts

Massachusetts has 3,445 paid clinical trials enrolling now across cities including Boston, Worcester and Burlington. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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2,953 clinical trials

A Study to Understand How the Study Medicine (PF-06823859) Works in People With Active Idiopathic Inflammatory Myopathies [Dermatomyositis (DM) and Polymyositis (PM)]

for Myositis

Sites in Boston +37 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT05895786·Phase 3·Recruiting·Listed Jun 2023

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A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC

for Adenocarcinoma, Pancreatic Ductal

Drug: Atezolizumab

Sites in Boston +29 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT05968326·Phase 2·Recruiting·Listed Aug 2023

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Study of Erdafitinib Intravesical Delivery System for Localized Bladder Cancer

for Non-Muscle Invasive Bladder Neoplasms

Sites in Plymouth +20 more locations

Sponsor: Janssen Research & Development, LLC

Sex: All·Age: 18+

Code: NCT05316155·Phase 1, Phase 2·Recruiting·Listed Apr 2022

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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

for Ulcerative Colitis

Sites in Boston +25 more locations

Sponsor: Spyre Therapeutics, Inc.

Sex: All·Age: 18 - 75

Code: NCT07012395·Phase 2·Recruiting·Listed Jun 2025

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A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

for Generalized Myasthenia Gravis

Drug: Telitacicept

Sites in Foxborough +25 more locations

Sponsor: Vor Biopharma

Sex: All·Age: 18+

Code: NCT06456580·Phase 3·Recruiting·Listed Jun 2024

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A Study to Evaluate the Efficacy and Safety of Sefaxersen (RO7434656) in Participants With Primary Immunoglobulin A (IgA) Nephropathy at High Risk of Progression

for Primary IgA Nephropathy

Sites in Boston +30 more locations

Sponsor: Hoffmann-La Roche

Sex: All·Age: 18+

Code: NCT05797610·Phase 3·Recruiting·Listed Apr 2023

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Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects

for Breast Cancer

Sites in Boston +48 more locations

Sponsor: Greenwich LifeSciences, Inc.

Sex: All·Age: 18 - 100

Code: NCT05232916·Phase 3·Recruiting·Listed Feb 2022

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

Sites in Boston, Worcester +63 more locations

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting·Listed Jun 2022

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Strategy for Improving Stroke Treatment Response

for Ischemic Stroke

Sites in Boston +42 more locations

Sponsor: Translational Sciences, Inc.

Sex: All·Age: 18+

Code: NCT05948566·Phase 2·Recruiting·Listed Jul 2023

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A Study of Ifinatamab Deruxtecan Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer

for Small Cell Lung Cancer

Sites in Boston +29 more locations

Sponsor: Daiichi Sankyo

Sex: All·Age: 18+

Code: NCT06203210·Phase 3·Recruiting·Listed Jan 2024

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A Study to Learn About the Effects of the Combination of Elranatamab (PF-06863135) and Iberdomide in Patients With Relapsed or Refractory Multiple Myeloma (MagnetisMM-30)

for Multiple Myeloma

Drug: Elranatamab

Sites in Boston, Worcester +32 more locations

Sponsor: Pfizer

Sex: All·Age: 18+

Code: NCT06215118·Phase 1·Recruiting·Listed Jan 2024

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Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration

for Neovascular Age-Related Macular Degeneration (nAMD)

Sites in Springfield +53 more locations

Sponsor: 4D Molecular Therapeutics

Sex: All·Age: 50+

Code: NCT07064759·Phase 3·Recruiting·Listed Jul 2025

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

Sites in Burlington +75 more locations

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT05899608·Phase 3·Recruiting·Listed Jun 2023

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A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Biliary Cholangitis

for Primary Biliary Cholangitis

Sites in Boston +29 more locations

Sponsor: Mirum Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT05050136·Phase 2·Recruiting·Listed Sep 2021

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A Study to Compare the Efficacy and Safety of Golcadomide in Combination With Rituximab (Golca + R) vs Investigator's Choice in Participants With Relapsed/Refractory Follicular Lymphoma Who Have Received at Least 1 Prior Line of Systemic Therapy (GOLSEEK-4)

for Follicular Lymphoma

Drug: Golcadomide

Sites in Boston +30 more locations

Sponsor: Celgene

Sex: All·Age: 18+

Code: NCT06911502·Phase 3·Recruiting·Listed Apr 2025

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NBI-1117568-SCZ3032: Long-Term Evaluation of NBI-1117568 in Adults With Schizophrenia

for Schizophrenia

Drug: NBI-1117568

Sites in Boston, Watertown +47 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18 - 65

Code: NCT07114874·Phase 3·Recruiting·Listed Aug 2025

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Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

for Major Depressive Disorder

Drug: NBI-1065845

Sites in Boston, Watertown +40 more locations

Sponsor: Neurocrine Biosciences

Sex: All·Age: 18+

Code: NCT06966401·Phase 3·Recruiting·Listed May 2025

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A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

for Aortic Stenosis

Drug: Pelacarsen

Sites in Boston +32 more locations

Sponsor: Novartis Pharmaceuticals

Sex: All·Age: 50 - 80

Code: NCT05646381·Phase 2·Recruiting·Listed Dec 2022

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COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

for Complex Congenital Heart Defect

Sites in Boston +20 more locations

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT02744677·Recruiting·Listed Apr 2016

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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting

for Pneumonia

Sites in Worcester +38 more locations

Sponsor: Pfizer

Sex: All·Age: 65+

Code: NCT05452941·Recruiting·Listed Jul 2022

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Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

for Multiple Myeloma

Sites in Boston +37 more locations

Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

Sex: All·Age: 18+

Code: NCT06297226·Phase 2·Recruiting·Listed Mar 2024

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[18F]PI-2620 Phase 3 Histopathological Study

for Alzheimer Disease

Sites in Braintree +19 more locations

Sponsor: Lantheus Biosciences Ltd.

Sex: All·Age: 50+

Code: NCT05641688·Phase 3·Recruiting·Listed Dec 2022

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

Sites in Boston, Worcester +31 more locations

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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A Long-term Extension Study of Dazodalibep in Participants With Sjögren's Syndrome (SS)

for Sjögren's Syndrome

Drug: Dazodalibep

Sites in Boston +30 more locations

Sponsor: Amgen

Sex: All·Age: 18+

Code: NCT06747949·Phase 3·Recruiting·Listed Dec 2024

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Rollover Study for Participants Previously Enrolled in Clinical Trials of Povorcitinib

for Hidradenitis Suppurativa (HS)

Drug: Povorcitinib

Sites in Boston, Brighton +93 more locations

Sponsor: Incyte Corporation

Sex: All·Age: 18+

Code: NCT06855498·Phase 3·Recruiting·Listed Mar 2025

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Pan Tumor Rollover Study

for Cancer

Sites in Boston +6 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT03899155·Phase 2·Recruiting·Listed Apr 2019

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A Study Evaluating Efruxifermin in Subjects With Non-Cirrhotic Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH) and Fibrosis

for NASH With Fibrosis

Drug: Efruxifermin

Sites in New Bedford +173 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06215716·Phase 3·Recruiting·Listed Jan 2024

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Clinical Study of Ivonescimab for First-line Treatment of Metastatic NSCLC Patients With High PD-L1

for Non-Small Cell Lung Cancer

Drug: Ivonescimab

Sites in Boston, Worcester +92 more locations

Sponsor: Summit Therapeutics

Sex: All·Age: 18+

Code: NCT06767514·Phase 3·Recruiting·Listed Jan 2025

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A Study of Azenosertib (ZN-c3) in Subjects With Platinum-Resistant High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

for High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer

Sites in Boston, Burlington +32 more locations

Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc

Sex: Female·Age: 18+

Code: NCT05128825·Phase 2·Recruiting·Listed Nov 2021

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A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

for Relapsing Multiple Sclerosis

Sites in Boston, Burlington +88 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT06433752·Recruiting·Listed May 2024

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A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)

for Major Depressive Disorder

Sites in Boston, Worcester +31 more locations

Sponsor: Xenon Pharmaceuticals Inc.

Sex: All·Age: 18 - 74

Code: NCT07076407·Phase 3·Recruiting·Listed Jul 2025

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Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

for Relapsing Multiple Sclerosis

Sites in Boston, Foxborough +32 more locations

Sponsor: TG Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT05877963·Phase 3·Recruiting·Listed May 2023

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A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH

for NASH - Nonalcoholic Steatohepatitis

Drug: Efruxifermin

Sites in South Dartmouth +154 more locations

Sponsor: Akero Therapeutics, Inc

Sex: All·Age: 18 - 80

Code: NCT06528314·Phase 3·Recruiting·Listed Jul 2024

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A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis

for Non-cystic Fibrosis Bronchiectasis

Sites in Boston +27 more locations

Sponsor: Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA

Sex: All·Age: 18 - 80

Code: NCT06559150·Phase 2·Recruiting·Listed Aug 2024

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A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH

for Metabolic Dysfunction-Associated Steatohepatitis (MASH) / Nonalcoholic Steatohepatitis (NASH) With Compensated Cirrhosis

Sites in Burlington +132 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 75

Code: NCT06419374·Phase 3·Recruiting·Listed May 2024

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A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis)

for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASH) / Nonalcoholic Steatohepatitis (NASH) With Fibrosis

Sites in Burlington +140 more locations

Sponsor: 89bio, Inc.

Sex: All·Age: 18 - 80

Code: NCT06318169·Phase 3·Recruiting·Listed Mar 2024

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

Sites in Boston, Fall River +131 more locations

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023

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CCM OPEN HF Registry

for Heart Failure

Sites in Boston +27 more locations

Sponsor: Impulse Dynamics

Sex: All·Age: 18+

Code: NCT07112924·Recruiting·Listed Aug 2025

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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II

for Refractory Angina

Sites in Boston, Springfield +63 more locations

Sponsor: Shockwave Medical, Inc.

Sex: All·Age: 18+

Code: NCT05102019·Recruiting·Listed Nov 2021

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Once Daily Versus Twice Daily Budesonide Orodispersible Tablets for Induction of Remission in EoE

for Eosinophilic Esophagitis

Sites in Boston +21 more locations

Sponsor: Dr. Falk Pharma GmbH

Sex: All·Age: 18 - 75

Code: NCT06596252·Phase 3·Recruiting·Listed Sep 2024

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