Paid Clinical Trials in Massachusetts

Massachusetts has 3,602 paid clinical trials enrolling now across cities including Boston, Worcester and Springfield. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Massachusetts include Mass General Hospital, Dana-Farber and Brigham and Women's, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: June 23, 2026.

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3,605 clinical trials

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Study Evaluating Safety and Efficacy of JCAR017 in Subjects With Relapsed or Refractory Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)

for Leukemia, Lymphocytic, Chronic, B-Cell

84 locations incl. Birmingham

Sponsor: Juno Therapeutics, a Subsidiary of Celgene

Sex: All·Age: 18+

Code: NCT03331198·Phase 1, Phase 2·Recruiting

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Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

for Heart Failure With Preserved Ejection Fraction

38 locations incl. Alexander City

Sponsor: Uppsala University

Sex: All·Age: 50 - 99

Code: NCT02901184·Phase 3·Recruiting

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Study of the CDK4/6 Inhibitor Abemaciclib in Solid Tumors Harboring Genetic Alterations in Genes Encoding D-Type Cyclins or Amplification of CDK4 or CDK6

for Cancer

1 location in Boston

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03310879·Phase 2·Recruiting

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Modern Immunotherapy in BCG-Unresponsive, BCG-Relapsing and High Risk BCG-Naive Non-Muscle Invasive Urothelial Carcinoma of the Bladder

for Urothelial Carcinoma

12 locations incl. Phoenix

Sponsor: Noah Hahn, M.D.

Sex: All·Age: 18+

Code: NCT03317158·Phase 1, Phase 2·Recruiting

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S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

for Cardiotoxicity

577 locations incl. Anchorage

Sponsor: SWOG Cancer Research Network

Sex: All·Age: 18+

Code: NCT03418961·Phase 3·Recruiting

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Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation.

for Mitral Valve Regurgitation

78 locations incl. Birmingham

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18+

Code: NCT03242642·Recruiting

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Molecular Imaging of NET Using [C-11]MRB-PET in MS

for Multiple Sclerosis

1 location in Boston

Sponsor: Brigham and Women's Hospital

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT03207464·Phase 1, Phase 2·Recruiting

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Genes and Environment in Multiple Sclerosis

for Multiple Sclerosis

5 locations incl. Bethesda

Sponsor: Columbia University

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT01353547·Recruiting

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APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

for Solid Tumors

6 locations incl. Los Angeles

Sponsor: Apollomics Inc.

Sex: All·Age: 18+

Code: NCT03175224·Phase 2·Recruiting

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OCT Guided Trans Nasal Imaging of the Small Intestine in Adults

for Environmental Enteric Dysfunction

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 60·Accepts healthy volunteers

Code: NCT04984447·Enrolling By Invitation

Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia

for B Acute Lymphoblastic Leukemia

455 locations incl. Birmingham

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18 - 39

Code: NCT03150693·Phase 3·Recruiting

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Fecal Microbiota Transplant National Registry

for Fecal Microbiota Transplantation

52 locations incl. Phoenix

Sponsor: American Gastroenterological Association

Sex: All·Age: All ages

Code: NCT03325855·Recruiting

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Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery

for Grade 2 Meningioma

197 locations incl. Birmingham

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT03180268·Phase 3·Recruiting

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CorEvitas Multiple Sclerosis (MS) Registry

for Multiple Sclerosis

1 location in Waltham

Sponsor: CorEvitas

Sex: All·Age: 18+

Code: NCT03291756·Enrolling By Invitation

Turmeric for Patients With Basal Joint Arthritis

for Thumb Osteoarthritis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 40+

Code: NCT03017118·Recruiting

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Transplantation of Autologously Derived Mitochondria Following Ischemia

for Extracorporeal Membrane Oxygenation Complication

1 location in Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: Up to 17

Code: NCT02851758·Recruiting

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Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

for Cardiac Arrest

5 locations incl. San Francisco

Sponsor: Boston Medical Center

Sex: All·Age: 18 - 89

Code: NCT03261089·Recruiting

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Inotuzumab Ozogamicin Post-Transplant For Acute Lymphocytic Leukemia

for Acute Lymphocytic Leukemia

7 locations incl. Westwood

Sponsor: Leland Metheny

Sex: All·Age: 16 - 75

Code: NCT03104491·Phase 1, Phase 2·Recruiting

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International Registry for Men With Advanced Prostate Cancer (IRONMAN)

for Prostate Cancer

48 locations incl. Birmingham

Sponsor: Prostate Cancer Clinical Trials Consortium

Sex: Male·Age: 21+

Code: NCT03151629·Recruiting

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Diffusion MRI in Heart Failure

for Heart Failure

1 location in Charlestown

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 85·Accepts healthy volunteers

Code: NCT02973633·EARLY_Phase 1·Recruiting

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SL-401 in Combination With Azacitidine or Azacitidine/Venetoclax in Acute Myeloid Leukemia (AML), High-Risk Myelodysplastic Syndrome (MDS) or Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN)

for Acute Myeloid Leukemia

Drug: Venetoclax

3 locations incl. Duarte

Sponsor: Dana-Farber Cancer Institute

Sex: All·Age: 18+

Code: NCT03113643·Phase 1·Recruiting

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Inotuzumab Ozogamicin in Treating Younger Patients With B-Lymphoblastic Lymphoma or Relapsed or Refractory CD22 Positive B Acute Lymphoblastic Leukemia

for Recurrent B Acute Lymphoblastic Leukemia

156 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: 1 - 21

Code: NCT02981628·Phase 2·Recruiting

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Stroke Motor Rehabilitation and Recovery Study

for Stroke, Ischemic

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18 - 90

Code: NCT03485040·Recruiting

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Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

for Childhood Extracranial Germ Cell Tumor

566 locations incl. Birmingham

Sponsor: Children's Oncology Group

Sex: All·Age: All ages

Code: NCT03067181·Phase 3·Recruiting

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Precision Diagnostics in Inflammatory Bowel Disease, Cellular Therapy and Transplantation (The PREDICT Trial)

for Graft Vs Host Disease

4 locations incl. Boston

Sponsor: Boston Children's Hospital

Sex: All·Age: All ages

Code: NCT03369353·Enrolling By Invitation

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

for Breast Cancer

130 locations incl. Birmingham

Sponsor: Agendia

Sex: All·Age: 18+

Code: NCT03053193·Recruiting

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Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

for Malignant Peripheral Nerve Sheath Tumors

9 locations incl. Tampa

Sponsor: Washington University School of Medicine

Sex: All·Age: All ages

Code: NCT03141021·Recruiting

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Veterans Affairs Lung Cancer Surgery Or Stereotactic Radiotherapy

for Lung Neoplasm

17 locations incl. Long Beach

Sponsor: VA Office of Research and Development

Sex: All·Age: 18+

Code: NCT02984761·Recruiting

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CorEvitas Inflammatory Bowel Disease (IBD) Registry

for Inflammatory Bowel Diseases

1 location in Waltham

Sponsor: CorEvitas

Sex: All·Age: 18+

Code: NCT03162549·Enrolling By Invitation

MILD® Percutaneous Image-Guided Lumbar Decompression: A Medicare Claims Study

for Lumbar Spinal Stenosis

2307 locations incl. Athens

Sponsor: Stryker Instruments

Sex: All·Age: 18+

Code: NCT03072927·Recruiting

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A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

for Locally Advanced Solid Tumors

Drug: Repotrectinib

49 locations incl. Duarte

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: 12+

Code: NCT03093116·Phase 1, Phase 2·Recruiting

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INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

for Glioblastoma

12 locations incl. Birmingham

Sponsor: Patrick Wen, MD

Sex: All·Age: 18+

Code: NCT02977780·Phase 2·Recruiting

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Palbociclib and Pembrolizumab In Central Nervous System Metastases

for Metastatic Malignant Neoplasm to Brain

2 locations incl. Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT02896335·Phase 2·Recruiting

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Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

for Homocystinuria Due to CBS Deficiency

7 locations incl. Culver City

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 1 - 65

Code: NCT02998710·Recruiting

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Clinical Transcriptomics in Systemic Vasculitis (CUTIS)

for Cryoglobulinemic Vasculitis (CV)

8 locations incl. Los Angeles

Sponsor: Peter Merkel

Sex: All·Age: 5+

Code: NCT03004326·Recruiting

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Partners Calciphylaxis Biobank

for Calciphylaxis

1 location in Boston

Sponsor: Massachusetts General Hospital

Sex: All·Age: 18+

Code: NCT03032835·Recruiting

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Imaging Genetics of Laryngeal Dystonia

for Laryngeal Dystonia

1 location in Boston

Sponsor: Kristina Simonyan

Sex: All·Age: All ages

Code: NCT03042975·Recruiting

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PARTNER 3 Trial - Aortic Valve-in-Valve

for Aortic Stenosis

50 locations incl. Phoenix

Sponsor: Edwards Lifesciences

Sex: All·Age: All ages

Code: NCT03003299·Recruiting

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A Randomized Multicenter Study for Isolated Skin Vasculitis

for Primary Cutaneous Vasculitis

12 locations incl. Kansas City

Sponsor: University of Pennsylvania

Sex: All·Age: 18+

Code: NCT02939573·Phase 2·Recruiting

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The Myelin Disorders Biorepository Project

for Leukodystrophy

23 locations incl. Los Angeles

Sponsor: Children's Hospital of Philadelphia

Sex: All·Age: All ages

Code: NCT03047369·Recruiting

Apply to this trial