Paid Clinical Trials in Maryland

Maryland has 2,752 paid clinical trials enrolling now across cities including Baltimore, Bethesda and Rockville. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Research sites in Maryland include Johns Hopkins Medicine and NIH Clinical Center, running studies across oncology, cardiology, neurology, and more. Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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2,407 clinical trials

Acoustic Stimulation During Restricted Sleep After Sleep Deprivation

for Sleep Deprivation

1 location in Silver Spring

Sponsor: Walter Reed Army Institute of Research (WRAIR)

Sex: All·Age: 18 - 39·Accepts healthy volunteers

Code: NCT05309473·Recruiting·Listed Apr 2022

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The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

for Thyroid Eye Disease

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT06275373·Recruiting·Listed Feb 2024

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Evaluation of the SafeSpace App Intervention

for Health Behavior

1 location in Bethesda

Sponsor: Child Trends

Sex: Female·Age: 14 - 18·Accepts healthy volunteers

Code: NCT06043596·Recruiting·Listed Sep 2023

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Phase 2 Safety and Immunogenicity Study of Rift Valley Fever Vaccine

for Rift Valley Fever

1 location in Fort Deterick

Sponsor: U.S. Army Medical Research and Development Command

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT03609398·Phase 2·Recruiting·Listed Aug 2018

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Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder

for Overactive Bladder

1 location in Bethesda

Sponsor: Walter Reed National Military Medical Center

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT04020510·Phase 4·Recruiting·Listed Jul 2019

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A Study To Assess the Safety, Tolerability, and Efficacy of Imzokitug in Combination With Pumitamig and Platinum-Doublet Chemotherapy (PDCT) Versus Pumitamig and PDCT as First-line Treatment for Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)

for Locally Advanced Non-Small Cell Lung Cancer (NSCLC)

Drug: Pumitamig

Sites in Baltimore +10 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07680764·Phase 2·Recruiting·Listed Jul 2, 2026

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A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM

for Weight Management

Sites in Baltimore, Potomac +53 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07667803·Phase 3·Recruiting·Listed Jun 25, 2026

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A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Bowie +23 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662044·Phase 3·Recruiting·Listed Jun 23, 2026

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A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Dapagliflozin

Sites in Annapolis, Oxon Hill +37 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662109·Phase 3·Recruiting·Listed Jun 23, 2026

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A Study to Find Out if the Study Drug Elecoglipron Helps Adults With Type 2 Diabetes Mellitus by Comparing it With Semaglutide, a Medicine Already Used to Treat Type 2 Diabetes Mellitus

for Type 2 Diabetes Mellitus

Drug: Semaglutide

Sites in Rockville +62 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07662213·Phase 3·Recruiting·Listed Jun 23, 2026

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DReAMzz- Dronabinol and Acetazolamide Medication for Sleep Apnea (ZZ). Dose Confirmation Crossover Study for IHL-42X in Subjects With Obstructive Sleep Apnea.

for Obstructive Sleep Apnea (OSA)

Sites in Rockville +13 more locations

Sponsor: Incannex Healthcare Ltd

Sex: All·Age: 18 - 65

Code: NCT07635563·Phase 2·Recruiting·Listed Jun 9, 2026

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A Phase IIb Study to Evaluate AZD8965 in Participants With IPF.

for Idiopathic Pulmonary Fibrosis (IPF)

Sites in Baltimore +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 40+

Code: NCT07652658·Phase 2·Recruiting·Listed Jun 17, 2026

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A Phase 2 Study to Evaluate the Pharmacodynamics, Safety and Tolerability of BGE-102 in Participants With Obesity and Cardiovascular Risk Factors

for Obesity and Cardiovascular Risk

Sites in Rockville +11 more locations

Sponsor: BioAge Labs, Inc.

Sex: All·Age: 18+

Code: NCT07656727·Phase 2·Recruiting·Listed Jun 18, 2026

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Psilocybin Efficacy With or Without Pimavanserin Pretreatment

for Mood (Psychological Function)

1 location in Baltimore

Sponsor: Johns Hopkins University

Sex: All·Age: 21 - 65·Accepts healthy volunteers

Code: NCT07610135·Phase 1, Phase 2·Recruiting·Listed May 2026

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A Study to Identify and Characterize Patients With Type 2 Diabetes Mellitus for Possible Participation in Ongoing or Future Type 2 Diabetes Mellitus Clinical Studies

for Type 2 Diabetes

Sites in Potomac +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07606066·Recruiting·Listed May 2026

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Adaptive Mobile Interventions to Reduce Cancer Risk Behaviors

for Smoking Cessation

1 location in Baltimore

Sponsor: Johns Hopkins Bloomberg School of Public Health

Sex: All·Age: 18 - 40·Accepts healthy volunteers

Code: NCT07585357·Recruiting·Listed May 2026

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A Study to Assess the Effect of Surovatamig in Adult Participants With Antibody-mediated Kidney Disease

for Primary Membranous Nephropathy

Sites in Bethesda +5 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 75

Code: NCT07571746·Phase 2·Recruiting·Listed May 2026

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DAREON®-NEC-1: A Study in People With Advanced Extrapulmonary Neuroendocrine Cancer (epNEC) to Compare Obrixtamig Plus Carboplatin and Etoposide Treatment With Standard Chemotherapy

for Extrapulmonary Neuroendocrine Cancer (epNEC)

Drug: Obrixtamig

Sites in Baltimore +20 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 18+

Code: NCT07544654·Phase 3·Recruiting·Listed Apr 2026

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A Study to Investigate the Safety and PK of VH4770359 in Healthy Participants

for HIV Infections

1 location in Baltimore

Sponsor: ViiV Healthcare

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07525544·Phase 1·Recruiting·Listed Apr 2026

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ALTO-207 in Adults With Treatment-resistant Depression (TRD)

for Treatment-resistant Depression (TRD)

Sites in Annapolis, Pikesville +36 more locations

Sponsor: Alto Neuroscience

Sex: All·Age: 18 - 75

Code: NCT07553637·Phase 2·Recruiting·Listed Apr 2026

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A Study to Investigate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD1043 in Healthy Adult Participants Living With Overweight and/or Obesity.

for Healthy Participants

Sites in Brooklyn +1 more location

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65·Accepts healthy volunteers

Code: NCT07511205·Phase 1·Recruiting·Listed Apr 2026

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A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

for Solid Tumors

Sites in Baltimore +15 more locations

Sponsor: Bristol-Myers Squibb

Sex: All·Age: 18+

Code: NCT07492680·Phase 2·Recruiting·Listed Mar 2026

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Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

for Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms

Drug: Solriamfetol

Sites in Pikesville +39 more locations

Sponsor: Axsome Therapeutics, Inc.

Sex: All·Age: 18 - 65

Code: NCT07484217·Phase 3·Recruiting·Listed Mar 2026

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A Study Comparing Higher Dose Chemotherapy Over a Shorter Amount of Time to Lower Dose Chemotherapy Plus Maintenance Over a Longer Amount of Time in Patients With Newly Diagnosed Intermediate-Risk Rhabdomyosarcoma (IR RMS)

for Rhabdomyosarcoma

Sites in Baltimore +61 more locations

Sponsor: Children's Oncology Group

Sex: All·Age: Up to 50

Code: NCT07466316·Phase 3·Recruiting·Listed Mar 2026

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An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis

for Plaque Psoriasis

Sites in Rockville +15 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07449702·Phase 2·Recruiting·Listed Mar 2026

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52-week Open Label Safety-Tolerability Study

for Schizophrenia

Sites in Gaithersburg +22 more locations

Sponsor: LB Pharmaceuticals Inc.

Sex: All·Age: 18 - 65

Code: NCT07369154·Phase 3·Recruiting·Listed Jan 2026

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A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)

for Fibrosing Interstitial Lung Disease

Drug: Nerandomilast

Sites in Baltimore +6 more locations

Sponsor: Boehringer Ingelheim

Sex: All·Age: 2 - 17

Code: NCT07366034·Phase 3·Recruiting·Listed Jan 2026

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An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer.

for Stomatitis

Sites in Glenn Dale +29 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07357597·Phase 4·Recruiting·Listed Jan 2026

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Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

for Clostridioides Difficile Infection

Sites in Glen Burnie, Potomac +32 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07285213·Phase 2·Recruiting·Listed Dec 2025

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A Study to Investigate Safety, Tolerability, and Pharmacokinetics of AZD3974 in Healthy Participants

for Healthy Participants

Sites in Baltimore +1 more location

Sponsor: AstraZeneca

Sex: All·Age: 18 - 55·Accepts healthy volunteers

Code: NCT07290283·Phase 1·Recruiting·Listed Dec 2025

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Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis

for Plaque Psoriasis

Sites in Rockville +19 more locations

Sponsor: Oruka Therapeutics, Inc.

Sex: All·Age: 18+

Code: NCT07290569·Phase 2·Recruiting·Listed Dec 2025

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Phase III Study of Datopotamab Deruxtecan Versus Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous NSCLC Without Actionable Genomic Alterations

for Non-small Cell Lung Cancer (NSCLC)

Sites in Baltimore, Brandywine +46 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07291037·Phase 3·Recruiting·Listed Dec 2025

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A Study to Investigate Efficacy and Safety of AZD1163 in Participants With Rheumatoid Arthritis

for Rheumatoid Arthritis

Sites in Baltimore +21 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07276581·Phase 2·Recruiting·Listed Dec 2025

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PRE-EMPT: Prospective RandomizEd Evaluation and Management of Premature aTherosclerosis

for Coronary Artery Disease Risk Factors Multiple

Sites in Baltimore +22 more locations

Sponsor: Duke University

Sex: All·Age: 30 - 60

Code: NCT07232069·Phase 3·Recruiting·Listed Nov 2025

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Safety, Tolerability and Pharmacokinetics of AZD1613 in Adults With Autosomal Dominant Polycystic Kidney Disease

for Autosomal Dominant Polycystic Kidney Disease

Sites in Baltimore +7 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 65

Code: NCT07228364·Phase 1·Recruiting·Listed Nov 2025

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A Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin in Combination With Standard of Care in Participants With Relapsed-Refractory Multiple Myeloma (RRMM)

for Multiple Myeloma

Drug: Belantamab mafodotin

Sites in Bethesda +10 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18+

Code: NCT07227311·Phase 2·Recruiting·Listed Nov 2025

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A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02)

for Biliary Tract Cancer

Drug: Rilvegostomig

Sites in Baltimore +34 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18+

Code: NCT07221253·Phase 3·Recruiting·Listed Oct 2025

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AZD5335 vs. Mirvetuximab Soravtansine in FRα-high and AZD5335 vs. Chemotherapy in FRα-low Platinum-resistant Ovarian Cancer

for Epithelial Ovarian Cancer

Sites in Towson +38 more locations

Sponsor: AstraZeneca

Sex: Female·Age: 18+

Code: NCT07218809·Phase 3·Recruiting·Listed Oct 2025

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A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

for Sepsis

Sites in Baltimore +13 more locations

Sponsor: AstraZeneca

Sex: All·Age: 18 - 80

Code: NCT07215702·Phase 2·Recruiting·Listed Oct 2025

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A Study to Assess the Effectiveness and Safety of GSK3862995B in Adults With Bronchiectasis

for Bronchiectasis

Sites in Rockville +13 more locations

Sponsor: GlaxoSmithKline

Sex: All·Age: 18 - 85

Code: NCT07201051·Phase 2·Recruiting·Listed Oct 2025

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