Paid Clinical Trials in Maine

Maine has 213 paid clinical trials enrolling now across cities including Scarborough, Portland and Bangor. Search by condition, age, or phase to find compensated research studies accepting participants near you.

Both patients and healthy volunteers may qualify. Most studies offer compensation for time and travel.

Recruiting trial data synced daily from ClinicalTrials.gov. Last sync: July 31, 2026.

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196 clinical trials

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

for Aortic Stenosis

Sites in Portland +70 more locations

Sponsor: Medtronic Cardiovascular

Sex: All·Age: 18 - 105

Code: NCT06777368·Recruiting·Listed Jan 2025

Apply to this trial

The THOR IDE Study

for Peripheral Artery Disease

Sites in Portland +28 more locations

Sponsor: Philips Clinical & Medical Affairs Global

Sex: All·Age: 18+

Code: NCT05916950·Recruiting·Listed Jun 2023

Apply to this trial

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

for Breast Cancer

Drug: Palazestrant

Sites in Scarborough +22 more locations

Sponsor: Olema Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT07085767·Phase 3·Recruiting·Listed Jul 2025

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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD

for AMD

Sites in Portland +64 more locations

Sponsor: AbbVie

Sex: All·Age: 50 - 89

Code: NCT05407636·Phase 3·Recruiting·Listed Jun 2022

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Nectero EAST System Clinical Study

for Abdominal Aortic Aneurysm

Sites in Scarborough +32 more locations

Sponsor: Nectero Medical, Inc.

Sex: All·Age: 21 - 85

Code: NCT06001918·Phase 2, Phase 3·Recruiting·Listed Aug 2023

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Study to evaLuate the effIcacy and Safety of abeLacimab in High-risk Patients With Atrial Fibrillation Who Have Been Deemed Unsuitable for Oral antiCoagulation (LILAC-TIMI 76)

for Atrial Fibrillation (AF)

Drug: Abelacimab

Sites in Bangor +132 more locations

Sponsor: Anthos Therapeutics, Inc.

Sex: All·Age: 65+

Code: NCT05712200·Phase 3·Recruiting·Listed Feb 2023

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International Collaborative Gaucher Group (ICGG) Gaucher Disease Registry & Pregnancy Sub-registry

for Gaucher Disease

Sites in Portland +69 more locations

Sponsor: Genzyme, a Sanofi Company

Sex: All·Age: All ages

Code: NCT00358943·Recruiting·Listed Aug 2006

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A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

for Metastatic Head-and-neck Squamous-cell Carcinoma

Sites in South Portland +24 more locations

Sponsor: AVEO Pharmaceuticals, Inc.

Sex: All·Age: 18+

Code: NCT06064877·Phase 3·Recruiting·Listed Oct 2023

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MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

for Breast Cancer

Sites in Portland +112 more locations

Sponsor: Agendia

Sex: All·Age: 18+

Code: NCT03053193·Recruiting·Listed Feb 2017

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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

for Bladder Carcinoma

Sites in Lewiston +26 more locations

Sponsor: Guardant Health, Inc.

Sex: All·Age: 18+

Code: NCT05059444·Recruiting·Listed Sep 2021

Apply to this trial

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

for Cancer, Metastatic

Sites in Scarborough +66 more locations

Sponsor: Massive Bio, Inc.

Sex: All·Age: All ages

Code: NCT03452774·Recruiting·Listed Mar 2018

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Prevalence of Antibodies and Cytokines in Participants With Chronic Granulomatous Disease

for Chronic Granulomatous Disease (CGD)

Sites in Augusta +49 more locations

Sponsor: Ensoma

Sex: All·Age: All ages

Code: NCT06605378·Recruiting·Listed Sep 2024

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A Study to Learn About the Safety, Tolerability, and Immunogenicity of a Fifth Dose of 6-Valent OspA-Based Lyme Disease Vaccine

for Lyme Disease

Sites in Bangor +18 more locations

Sponsor: Pfizer

Sex: All·Age: 7+·Accepts healthy volunteers

Code: NCT07500506·Phase 3·Recruiting·Listed Mar 2026

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A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

for Ovarian Neoplasms

Sites in Scarborough +13 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: Female·Age: 18+

Code: NCT07318558·Phase 3·Recruiting·Listed Jan 2026

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Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects

for Asthma

Sites in Bangor +12 more locations

Sponsor: Biometry Inc

Sex: All·Age: 5 - 100

Code: NCT07228026·Recruiting·Listed Nov 2025

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A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

for Non-small Cell Lung Cancer

Drug: Calderasib

Sites in Westbrook +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07190248·Phase 3·Recruiting·Listed Sep 2025

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A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer

for Breast Cancer

Drug: Giredestrant

Sites in Detroit +19 more locations

Sponsor: Genentech, Inc.

Sex: All·Age: 18+

Code: NCT07100106·Phase 1, Phase 2·Recruiting·Listed Aug 2025

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A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma

for Metastatic Gastric Adenocarcinoma

Sites in Westbrook +18 more locations

Sponsor: BeOne Medicines

Sex: All·Age: 18+

Code: NCT07043400·Phase 3·Recruiting·Listed Jun 2025

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Sacituzumab Tirumotecan (MK-2870) in Combination With Pembrolizumab Versus Pembrolizumab Alone in Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥ 50% (MK-2870-007)

for Non-small Cell Lung Cancer (NSCLC)

Sites in Westbrook +9 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT06170788·Phase 3·Recruiting·Listed Dec 2023

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Study of Sacituzumab Govitecan Versus Standard of Care in Participants With Previously Treated Extensive Stage Small Cell Lung Cancer

for Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Sites in Scarborough +20 more locations

Sponsor: Gilead Sciences

Sex: All·Age: 18+

Code: NCT06801834·Phase 3·Recruiting·Listed Jan 2025

Apply to this trial

Registry on NeVa VS for CerebraL VAsospasm ManagemenT in Post SAH PatiEnts

for Cerebral Vasospasm

Sites in Portland +15 more locations

Sponsor: Vesalio

Sex: All·Age: 22+

Code: NCT06893588·Recruiting·Listed Mar 2025

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A Study to Investigate Efficacy and Safety of Pegtibatinase Compared With Placebo in Participants ≥12 to ≤65 Years of Age With Classical Homocystinuria (HCU) Due to Cystathionine Beta Synthase Deficiency Receiving Standard of Care Treatment

for Homocystinuria

Sites in Portland +12 more locations

Sponsor: Travere Therapeutics, Inc.

Sex: All·Age: 12 - 65

Code: NCT06247085·Phase 3·Recruiting·Listed Feb 2024

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A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

for Locally Advanced Solid Tumors

Drug: Repotrectinib

Sites in Scarborough +11 more locations

Sponsor: Turning Point Therapeutics, Inc.

Sex: All·Age: Up to 25

Code: NCT04094610·Phase 1, Phase 2·Recruiting·Listed Sep 2019

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A Clinical Trial to Evaluate Efficacy, Safety, and Pharmacokinetics of Gamunex in Participants With Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma

for Chronic Lymphocytic Leukemia, Multiple Myeloma, or Non-Hodgkin Lymphoma

Sites in Westbrook +4 more locations

Sponsor: Grifols Biologicals, LLC

Sex: All·Age: 18+

Code: NCT07582432·Phase 3·Recruiting·Listed May 2026

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AMG 436 as Monotherapy and Combination Therapy in Participants With MSI-H/dMMR Solid Tumors

for Metastatic or Locally Advanced Solid Tumors With Microsatellite Instability-high (MSI-H) or Mismatched Repair Deficiency (dMMR)

Drug: AMG 436

Sites in Westbrook +5 more locations

Sponsor: Amgen

Sex: All·Age: 18 - 99

Code: NCT07403721·Phase 1·Recruiting·Listed Feb 2026

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A Clinical Study of Belzutifan and Zanzalintinib in People With Recurrent Kidney Cancer Following Adjuvant Therapy (MK-6482-033)

for Renal Cell Carcinoma

Sites in Westbrook +8 more locations

Sponsor: Merck Sharp & Dohme LLC

Sex: All·Age: 18+

Code: NCT07227402·Phase 3·Recruiting·Listed Nov 2025

Apply to this trial

Clinical Outcome Measure at Stryker Spine

for Degenerative Disc Disease

Sites in Scarborough +6 more locations

Sponsor: VB Spine, LLC

Sex: All·Age: 18+

Code: NCT06226272·Recruiting·Listed Jan 2024

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Outcomes Following Combined Adductoplasty™ and Lapiplasty® (MTA3D)

for Metatarsus Adductus

Sites in Yarmouth +8 more locations

Sponsor: Treace Medical Concepts, Inc.

Sex: All·Age: 14 - 65·Accepts healthy volunteers

Code: NCT05587569·Recruiting·Listed Oct 2022

Apply to this trial

Improving Health Outcomes Through Investigations of Wabanaki Food Systems in Maine

for Food Insecurity

1 location in Bangor

Sponsor: Wabanaki Public Health and Wellness

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07561593·Recruiting·Listed May 2026

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Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays

for Ampulla of Vater Carcinoma

Sites in Scarborough, South Portland +330 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+·Accepts healthy volunteers

Code: NCT07283939·Recruiting·Listed Dec 2025

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Testing the Addition of an Antiangiogenic Drug (Bevacizumab) to Chemotherapy (Carboplatin and Paclitaxel) Combined With Immunotherapy (Pembrolizumab) for pMMR, TP53 Mutated Endometrial Cancer

for Advanced Endometrial Carcinoma

Drug: Bevacizumab

Sites in Scarborough, Brewer +235 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07198074·Phase 3·Recruiting·Listed Sep 2025

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Testing Addition of an Anti-cancer Drug, Vorasidenib to Temozolomide, After Radiation for Advanced Brain Cancer

for Astrocytoma, IDH-Mutant, Grade 3

Drug: Vorasidenib

Sites in Scarborough, Portland +80 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 12+

Code: NCT07215910·Phase 3·Recruiting·Listed Oct 2025

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Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer

for Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8

Sites in Brewer +100 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT07195734·Phase 2·Recruiting·Listed Sep 2025

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Testing the Addition of a Type of Drug Called Immunotherapy to the Usual Chemotherapy Treatment for Non-small Cell Lung Cancer, an ALCHEMIST Treatment Trial (Chemo-IO [ACCIO])

for Lung Non-Small Cell Carcinoma

Sites in Scarborough, Bangor +633 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04267848·Phase 3·Recruiting·Listed Feb 2020

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Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

for Breast Cancer

Sites in Scarborough, South Portland +1103 more locations

Sponsor: NRG Oncology

Sex: Female·Age: 18 - 60

Code: NCT05879926·Phase 3·Recruiting·Listed May 2023

Apply to this trial

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

for Stage III Colon Cancer

Sites in Scarborough, South Portland +920 more locations

Sponsor: NRG Oncology

Sex: All·Age: 18+

Code: NCT05174169·Phase 2, Phase 3·Recruiting·Listed Dec 2021

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Induction Pembrolizumab and Chemotherapy Followed by Pembrolizumab Before Chemoradiation and Pembrolizumab Maintenance Compared to Standard Chemoradiation With Pembrolizumab Followed by Pembrolizumab Maintenance in High-Risk Cervical Cancer

for Locally Advanced Cervical Adenocarcinoma

Sites in Scarborough, Portland +294 more locations

Sponsor: National Cancer Institute (NCI)

Sex: Female·Age: 18+

Code: NCT07061977·Phase 3·Recruiting·Listed Jul 2025

Apply to this trial

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

for Chronic Lymphocytic Leukemia

Sites in Scarborough, Portland +296 more locations

Sponsor: National Cancer Institute (NCI)

Sex: All·Age: 18+

Code: NCT04269902·Phase 3·Recruiting·Listed Feb 2020

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ShortStop-HER2: 12 Months vs. 6 Months of HER2-targeted Medications for People With HER2+ Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Trastuzumab

for Anatomic Stage I Breast Cancer AJCC v8

Sites in Scarborough, South Portland +583 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 18+

Code: NCT06876714·Phase 3·Recruiting·Listed Mar 2025

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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

for Acute Lymphoblastic Leukemia

Sites in Scarborough, Portland +629 more locations

Sponsor: Alliance for Clinical Trials in Oncology

Sex: All·Age: 40 - 75·Accepts healthy volunteers

Code: NCT05334069·Recruiting·Listed Apr 2022

Apply to this trial